4-aminobutyric acid is a lipid of Fatty Acyls (FA) class. 4-aminobutyric acid is associated with abnormalities such as Epilepsy and Premenstrual syndrome. The involved functions are known as Binding (Molecular Function), neuron survival, Process, Uptake and physiological aspects. 4-aminobutyric acid often locates in Microglial, Neurofilament, Neuraxis, Brain region and Neurites. The associated genes with 4-aminobutyric acid are arginine methyl ester, SLC33A1 gene, NKS1 gene, P4HTM gene and ITSN2 gene. The related lipids are pregnenolone sulfate, pregnane-20-one, Pregnanes, Steroids and endogenous steroids.
To understand associated biological information of 4-aminobutyric acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
4-aminobutyric acid is suspected in Premenstrual syndrome, Epilepsy and other diseases in descending order of the highest number of associated sentences.
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We collected disease MeSH terms mapped to the references associated with 4-aminobutyric acid
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
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Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Gene | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Tredway TL et al. | N-type voltage-dependent calcium channels mediate the nicotinic enhancement of GABA release in chick brain. | 1999 | J. Neurophysiol. | pmid:10036250 |
Dumoulin A et al. | Presence of the vesicular inhibitory amino acid transporter in GABAergic and glycinergic synaptic terminal boutons. | 1999 | J. Cell. Sci. | pmid:10036231 |
Lake N and Voaden MJ | Exchange versus net uptake of exogenously-applied gamma-aminobutyric acid in retina. | 1976 | J. Neurochem. | pmid:1003234 |
Lodge D et al. | The uptake of GABA and beta-alanine in slices of cat and rat CNS tissue: regional differences in susceptibility to inhibitors. | 1976 | J. Neurochem. | pmid:1003233 |
Perry TL and Hansen S | Is GABA detectable in human CSF? | 1976 | J. Neurochem. | pmid:1003229 |
Corrigall WA et al. | Electrophysiological studies of fetal mouse olifactory bulb explants during development of synaptic functions in culture. | 1976 | J. Neurobiol. | pmid:1003199 |
Mikati MA et al. | Gabapentin in the treatment of refractory partial epilepsy in children with intellectual disability. | 1998 | J Intellect Disabil Res | pmid:10030434 |
Ylinen A | Antiepileptic efficacy of vigabatrin in people with severe epilepsy and intellectual disability. | 1998 | J Intellect Disabil Res | pmid:10030432 |
Renno WM et al. | Quantitative immunoelectron microscopic colocalization of GABA and enkephalin in the ventrocaudal periaqueductal gray of the rat. | 1999 | Synapse | pmid:10029240 |
Bird M and Owen A | Neurite outgrowth-regulating properties of GABA and the effect of serum on mouse spinal cord neurons in culture. | 1998 | J. Anat. | pmid:10029183 |