4-aminobutyric acid

4-aminobutyric acid is a lipid of Fatty Acyls (FA) class. 4-aminobutyric acid is associated with abnormalities such as Epilepsy and Premenstrual syndrome. The involved functions are known as Binding (Molecular Function), neuron survival, Process, Uptake and physiological aspects. 4-aminobutyric acid often locates in Microglial, Neurofilament, Neuraxis, Brain region and Neurites. The associated genes with 4-aminobutyric acid are arginine methyl ester, SLC33A1 gene, NKS1 gene, P4HTM gene and ITSN2 gene. The related lipids are pregnenolone sulfate, pregnane-20-one, Pregnanes, Steroids and endogenous steroids.

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Introduction

To understand associated biological information of 4-aminobutyric acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with 4-aminobutyric acid?

4-aminobutyric acid is suspected in Premenstrual syndrome, Epilepsy and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with 4-aminobutyric acid

MeSH term MeSH ID Detail
Dysarthria D004401 2 associated lipids
Neck Pain D019547 2 associated lipids
Diplopia D004172 2 associated lipids
Epilepsy, Tonic-Clonic D004830 2 associated lipids
Low Back Pain D017116 2 associated lipids
Hamartoma D006222 2 associated lipids
Psychoses, Alcoholic D011604 2 associated lipids
Earache D004433 2 associated lipids
Esophageal and Gastric Varices D004932 2 associated lipids
Gyrate Atrophy D015799 2 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with 4-aminobutyric acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with 4-aminobutyric acid?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with 4-aminobutyric acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with 4-aminobutyric acid?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with 4-aminobutyric acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with 4-aminobutyric acid?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with 4-aminobutyric acid

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Authors Title Published Journal PubMed Link
Burkhart CN and Burkhart CG Another look at ivermectin in the treatment of scabies and head lice. 1999 Int. J. Dermatol. pmid:10208630
Boyd BW and Kennedy RT Determination of trace level gamma-aminobutyric acid using an improved OPA pre-column derivatization and on-column preconcentration capillary liquid chromatography with electrochemical detection. 1998 Analyst pmid:10209896
Erdal J et al. Changes in plasma GABA concentration during vigabatrin treatment of epilepsy: a prospective study. 1999 Epilepsy Res. pmid:10210029
Brodie MJ and Mumford JP Double-blind substitution of vigabatrin and valproate in carbamazepine-resistant partial epilepsy. 012 Study group. 1999 Epilepsy Res. pmid:10210035
pmid:10210670
Amabeoku GJ Gamma-aminobutyric acid and glutamic acid receptors may mediate theophylline-induced seizures in mice. 1999 Gen. Pharmacol. pmid:10211593
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Arndt CF et al. Outer retinal dysfunction in patients treated with vigabatrin. 1999 Neurology pmid:10214744
Papp EC et al. Medial septal and median raphe innervation of vasoactive intestinal polypeptide-containing interneurons in the hippocampus. 1999 Neuroscience pmid:10215142
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Rapallino MV et al. Stimulation of chloride in-->out permeation across the Deiters' neuron membrane by pentobarbital on the cytoplasmic side: additional evidence of GABA(A) receptors acting as chloride extrusion pumps. 1999 Neurochem. Res. pmid:10215521
Hu LA and King SC Identification of the amine-polyamine-choline transporter superfamily 'consensus amphipathic region' as the target for inactivation of the Escherichia coli GABA transporter GabP by thiol modification reagents. Role of Cys-300 in restoring thiol sensitivity to Gabp lacking Cys. 1999 Biochem. J. pmid:10215604
Xiong H et al. Mutual regulation between the intercellular messengers nitric oxide and brain-derived neurotrophic factor in rodent neocortical neurons. 1999 Eur. J. Neurosci. pmid:10215909
Ali AB et al. IPSPs elicited in CA1 pyramidal cells by putative basket cells in slices of adult rat hippocampus. 1999 Eur. J. Neurosci. pmid:10215927
Maruyama S and Kawasaki T Further electrophysiological evidence for the GABA-like effect of droperidol in the Purkinje cells of the cat cerebellum. 1976 Jpn. J. Pharmacol. pmid:1021614