| MeSH term | MeSH ID | Detail |
|---|---|---|
| Acidosis, Lactic | D000140 | 8 associated lipids |
| Adenocarcinoma | D000230 | 166 associated lipids |
| Adenoma | D000236 | 40 associated lipids |
| Adrenal Cortex Diseases | D000303 | 1 associated lipids |
| Adrenoleukodystrophy | D000326 | 29 associated lipids |
| Alcohol Amnestic Disorder | D000425 | 2 associated lipids |
| Alcoholic Intoxication | D000435 | 15 associated lipids |
| Alcoholism | D000437 | 27 associated lipids |
| Alzheimer Disease | D000544 | 76 associated lipids |
| Renal Aminoacidurias | D000608 | 2 associated lipids |
4-aminobutyric acid
4-aminobutyric acid is a lipid of Fatty Acyls (FA) class. 4-aminobutyric acid is associated with abnormalities such as Epilepsy and Premenstrual syndrome. The involved functions are known as Binding (Molecular Function), neuron survival, Process, Uptake and physiological aspects. 4-aminobutyric acid often locates in Microglial, Neurofilament, Neuraxis, Brain region and Neurites. The associated genes with 4-aminobutyric acid are arginine methyl ester, SLC33A1 gene, NKS1 gene, P4HTM gene and ITSN2 gene. The related lipids are pregnenolone sulfate, pregnane-20-one, Pregnanes, Steroids and endogenous steroids.
Cross Reference
Introduction
To understand associated biological information of 4-aminobutyric acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with 4-aminobutyric acid?
4-aminobutyric acid is suspected in Premenstrual syndrome, Epilepsy and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with 4-aminobutyric acid
PubChem Associated disorders and diseases
What pathways are associated with 4-aminobutyric acid
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with 4-aminobutyric acid?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with 4-aminobutyric acid?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with 4-aminobutyric acid?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
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What genes are associated with 4-aminobutyric acid?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with 4-aminobutyric acid?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with 4-aminobutyric acid
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Meye FJ et al. | Morphine withdrawal enhances constitutive μ-opioid receptor activity in the ventral tegmental area. | 2012 | J. Neurosci. | pmid:23152596 |
| Geng Y et al. | Triptolide down-regulates COX-2 expression and PGE2 release by suppressing the activity of NF-κB and MAP kinases in lipopolysaccharide-treated PC12 cells. | 2012 | Phytother Res | pmid:21717513 |
| Perego C et al. | Neurosteroid allopregnanolone regulates EAAC1-mediated glutamate uptake and triggers actin changes in Schwann cells. | 2012 | J. Cell. Physiol. | pmid:21688266 |
| Lin PP et al. | Inhibition of cardiac hypertrophy by probiotic-fermented purple sweet potato yogurt in spontaneously hypertensive rat hearts. | 2012 | Int. J. Mol. Med. | pmid:23064753 |
| Bracamontes JR et al. | A neurosteroid potentiation site can be moved among GABAA receptor subunits. | 2012 | J. Physiol. (Lond.) | pmid:22988137 |
| Garrido P et al. | Aging impairs the control of prefrontal cortex on the release of corticosterone in response to stress and on memory consolidation. | 2012 | Neurobiol. Aging | pmid:21794953 |
| Omoto JJ et al. | Functional consequences of sulfhydryl modification of the γ-aminobutyric acid transporter 1 at a single solvent-exposed cysteine residue. | 2012 | J. Membr. Biol. | pmid:22918627 |
| Osaka T | Thermoregulatory responses elicited by microinjection of L-glutamate and its interaction with thermogenic effects of GABA and prostaglandin E2 in the preoptic area. | 2012 | Neuroscience | pmid:22986159 |
| Huo S et al. | Cultivation of Chlorella zofingiensis in bench-scale outdoor ponds by regulation of pH using dairy wastewater in winter, South China. | 2012 | Bioresour. Technol. | pmid:22858469 |
| Lecker I et al. | Tranexamic acid concentrations associated with human seizures inhibit glycine receptors. | 2012 | J. Clin. Invest. | pmid:23187124 |
| Bellance N et al. | Oncosecretomics coupled to bioenergetics identifies α-amino adipic acid, isoleucine and GABA as potential biomarkers of cancer: Differential expression of c-Myc, Oct1 and KLF4 coordinates metabolic changes. | 2012 | Biochim. Biophys. Acta | pmid:22842522 |
| Shameem M and Patel AB | Glutamatergic and GABAergic metabolism in mouse brain under chronic nicotine exposure: implications for addiction. | 2012 | PLoS ONE | pmid:22848621 |
| Al-Wadei HA et al. | Celecoxib and GABA cooperatively prevent the progression of pancreatic cancer in vitro and in xenograft models of stress-free and stress-exposed mice. | 2012 | PLoS ONE | pmid:22916251 |
| Benjaminsen E et al. | A man in his seventies with prolonged myasthenic crisis. | 2012 | Tidsskr. Nor. Laegeforen. | pmid:23076489 |
| Sumracki NM et al. | The effects of pregabalin and the glial attenuator minocycline on the response to intradermal capsaicin in patients with unilateral sciatica. | 2012 | PLoS ONE | pmid:22685578 |
| Uetake K et al. | Calming effect of orally administered γ-aminobutyric acid in Shih Tzu dogs. | 2012 | Anim. Sci. J. | pmid:23216545 |
| Kilic FS et al. | Antinociceptive effects of gabapentin & its mechanism of action in experimental animal studies. | 2012 | Indian J. Med. Res. | pmid:22771591 |
| Maschio M et al. | Effect of pregabalin add-on treatment on seizure control, quality of life, and anxiety in patients with brain tumour-related epilepsy: a pilot study. | 2012 | Epileptic Disord | pmid:23248037 |
| Toyokura K et al. | Adaxial-abaxial patterning: a novel function of the GABA shunt. | 2012 | Plant Signal Behav | pmid:22751326 |
| Rossi S et al. | Interleukin-1β causes anxiety by interacting with the endocannabinoid system. | 2012 | J. Neurosci. | pmid:23035099 |