| MeSH term | MeSH ID | Detail |
|---|---|---|
| Acidosis, Lactic | D000140 | 8 associated lipids |
| Adenocarcinoma | D000230 | 166 associated lipids |
| Adenoma | D000236 | 40 associated lipids |
| Adrenal Cortex Diseases | D000303 | 1 associated lipids |
| Adrenoleukodystrophy | D000326 | 29 associated lipids |
| Alcohol Amnestic Disorder | D000425 | 2 associated lipids |
| Alcoholic Intoxication | D000435 | 15 associated lipids |
| Alcoholism | D000437 | 27 associated lipids |
| Alzheimer Disease | D000544 | 76 associated lipids |
| Renal Aminoacidurias | D000608 | 2 associated lipids |
4-aminobutyric acid
4-aminobutyric acid is a lipid of Fatty Acyls (FA) class. 4-aminobutyric acid is associated with abnormalities such as Epilepsy and Premenstrual syndrome. The involved functions are known as Binding (Molecular Function), neuron survival, Process, Uptake and physiological aspects. 4-aminobutyric acid often locates in Microglial, Neurofilament, Neuraxis, Brain region and Neurites. The associated genes with 4-aminobutyric acid are arginine methyl ester, SLC33A1 gene, NKS1 gene, P4HTM gene and ITSN2 gene. The related lipids are pregnenolone sulfate, pregnane-20-one, Pregnanes, Steroids and endogenous steroids.
Cross Reference
Introduction
To understand associated biological information of 4-aminobutyric acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with 4-aminobutyric acid?
4-aminobutyric acid is suspected in Premenstrual syndrome, Epilepsy and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with 4-aminobutyric acid
PubChem Associated disorders and diseases
What pathways are associated with 4-aminobutyric acid
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with 4-aminobutyric acid?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with 4-aminobutyric acid?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with 4-aminobutyric acid?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
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What genes are associated with 4-aminobutyric acid?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with 4-aminobutyric acid?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with 4-aminobutyric acid
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Bickford PC et al. | Effect of normobaric hyperoxia on two indexes of synaptic function in Fisher 344 rats. | 1999 | Free Radic. Biol. Med. | pmid:10232824 |
| Bonci A and Malenka RC | Properties and plasticity of excitatory synapses on dopaminergic and GABAergic cells in the ventral tegmental area. | 1999 | J. Neurosci. | pmid:10234004 |
| Smith Y et al. | CART peptide-immunoreactive neurones in the nucleus accumbens in monkeys: ultrastructural analysis, colocalization studies, and synaptic interactions with dopaminergic afferents. | 1999 | J. Comp. Neurol. | pmid:10235641 |
| Kozhechkin SN and Ostrovskaia RU | [Increase in the sensitivity of rabbit sensomotor cortex neurons to gamma-aminobutyric acid under the influence of diazepam (microiontophoretic study)]. | 1976 | Biull Eksp Biol Med | pmid:1023972 |
| Collins RC and Mehta S | Effect of amino-oxyacetic acid (AOAA) on focal penicillin seizures. | 1978 | Brain Res. | pmid:102408 |
| Szydlowska H and Kaluza J | Attempts at inhibition of autooxidation of catecholamines in vitro. | 1976 | Folia Histochem Cytochem (Krakow) | pmid:1024955 |
| Moiseenok AG et al. | [Characteristics of the antivitamin effect of pyriditol, a disulfide pyridoxine derivative, on animal body]. | 1976 May-Jun | Farmakol Toksikol | pmid:1026514 |
| Saad SF | The effect of certain parasympathomimetic and parasympatholytic drugs on the gamma-aminobutyric acid content in the cerebral hemispheres of mice. | 1976 | Mater Med Pol | pmid:1027954 |
| MaÄsov NI et al. | [Liberation of H3-GABA from isolated nerve endings of the cerebral cortex of rats under the effect of psychotropic drugs]. | 1976 Sep-Oct | Farmakol Toksikol | pmid:1028577 |
| Godovalova LA | [Effect of gamma-aminobutyric acid on peripheral mechanisms regulating autonomic functions]. | 1976 Nov-Dec | Farmakol Toksikol | pmid:1030668 |
| Pigareva ZD et al. | [Effect of early visual deprivation on the free amino acid and protein content in the brain formations of dogs]. | 1976 Mar-Apr | Vopr. Med. Khim. | pmid:1030888 |
| Komáromi I | The central effect of 5-hydroxytryptamine, gamma-amino-butyric acid and carbachol on thermoregulation in the neonatal guinea pig. | 1976 | Acta Physiol Acad Sci Hung | pmid:1031240 |
| Kobayashi K and Okada Y | Excitatory effects of adenosine are not mediated by inhibition of GABAergic system in slices of superior colliculus and hippocampus from guinea pig. | 1999 | Neurosci. Lett. | pmid:10320008 |
| He Y et al. | Differential synaptic distribution of the AMPA-GluR2 subunit on GABAergic and non-GABAergic neurons in the basolateral amygdala. | 1999 | Brain Res. | pmid:10320693 |
| Phillis JW et al. | Effects of hyperosmolarity and ion substitutions on amino acid efflux from the ischemic rat cerebral cortex. | 1999 | Brain Res. | pmid:10320719 |
| Freda BJ et al. | Cardiovascular responses to muscle contraction following microdialysis of nitric oxide precursor into ventrolateral medulla. | 1999 | Brain Res. | pmid:10320724 |
| Hayashi Y et al. | Pentylenetetrazol-induced kindling stimulates the polyamine interconversion pathway in rat brain. | 1999 | Brain Res. | pmid:10320741 |
| Wang LH and Tsai CL | Effects of gonadal steroids on the GABA and glutamate contents of the early developing tilapia brain. | 1999 | Brain Res. Dev. Brain Res. | pmid:10320768 |
| Koós T and Tepper JM | Inhibitory control of neostriatal projection neurons by GABAergic interneurons. | 1999 | Nat. Neurosci. | pmid:10321252 |
| Gessi S et al. | Temperature dependence and GABA modulation of beta-carboline binding to rat cerebellum benzodiazepine receptors. | 1999 | Life Sci. | pmid:10321727 |
| Caddick SJ et al. | Excitatory but not inhibitory synaptic transmission is reduced in lethargic (Cacnb4(lh)) and tottering (Cacna1atg) mouse thalami. | 1999 | J. Neurophysiol. | pmid:10322048 |
| Bolea S et al. | Glutamate controls the induction of GABA-mediated giant depolarizing potentials through AMPA receptors in neonatal rat hippocampal slices. | 1999 | J. Neurophysiol. | pmid:10322051 |
| Kapur J et al. | Physiological properties of GABAA receptors from acutely dissociated rat dentate granule cells. | 1999 | J. Neurophysiol. | pmid:10322081 |
| Bernasconi R et al. | Gamma-hydroxybutyric acid: an endogenous neuromodulator with abuse potential? | 1999 | Trends Pharmacol. Sci. | pmid:10322498 |
| Ali HI et al. | Effect of glucose on the action of some anaesthetics. | 1976 | J Egypt Med Assoc | pmid:1032312 |
| Eid T et al. | Ultrastructure and immunocytochemical distribution of GABA in layer III of the rat medial entorhinal cortex following aminooxyacetic acid-induced seizures. | 1999 | Exp Brain Res | pmid:10323293 |
| Skoglösa Y et al. | Pituitary adenylate cyclase activating polypepetide is expressed by developing rat Purkinje cells and decreases the number of cerebellar gamma-amino butyric acid positive neurons in culture. | 1999 | Neurosci. Lett. | pmid:10327167 |
| D'Hooge R et al. | Uraemic guanidino compounds inhibit gamma-aminobutyric acid-evoked whole cell currents in mouse spinal cord neurones. | 1999 | Neurosci. Lett. | pmid:10327174 |
| Zamponi N and Cardinali C | Open comparative long-term study of vigabatrin vs carbamazepine in newly diagnosed partial seizures in children. | 1999 | Arch. Neurol. | pmid:10328256 |
| Lawson SN et al. | The effect of electrophoretically applied GABA on cultured dissociated spinal cord and sensory ganglion neurones of the rat. | 1976 | Brain Res. | pmid:1033023 |
| Quaglino E et al. | Immunocytochemical localization of glutamate and gamma-aminobutyric acid in the accessory olfactory bulb of the rat. | 1999 | J. Comp. Neurol. | pmid:10331580 |
| Sankar R and Wasterlain CG | Is the devil we know the lesser of two evils? Vigabatrin and visual fields. | 1999 | Neurology | pmid:10331674 |
| Cossette P et al. | ACTH versus vigabatrin therapy in infantile spasms: a retrospective study. | 1999 | Neurology | pmid:10331702 |
| Vanhatalo S et al. | Visual field constriction in children treated with vigabatrin. | 1999 | Neurology | pmid:10331710 |
| Letterman L and Markowitz JS | Gabapentin: a review of published experience in the treatment of bipolar disorder and other psychiatric conditions. | 1999 | Pharmacotherapy | pmid:10331819 |
| Fucile S et al. | Comparison of glycine and GABA actions on the zebrafish homomeric glycine receptor. | 1999 | J. Physiol. (Lond.) | pmid:10332088 |
| Hyder F et al. | Localized 1H NMR measurements of 2-pyrrolidinone in human brain in vivo. | 1999 | Magn Reson Med | pmid:10332870 |
| Jongen-Rêlo AL et al. | Distribution of GABAergic cells and fibers in the hippocampal formation of the macaque monkey: an immunohistochemical and in situ hybridization study. | 1999 | J. Comp. Neurol. | pmid:10333273 |
| Bizon JL et al. | Subpopulations of striatal interneurons can be distinguished on the basis of neurotrophic factor expression. | 1999 | J. Comp. Neurol. | pmid:10333275 |
| Essman WB | Regional differences in GABA uptake. | 1976 | Neurology | pmid:1033490 |
| von Krosigk M et al. | Dynamic properties of corticothalamic excitatory postsynaptic potentials and thalamic reticular inhibitory postsynaptic potentials in thalamocortical neurons of the guinea-pig dorsal lateral geniculate nucleus. | 1999 | Neuroscience | pmid:10336055 |
| Rudkin TM and Sadikot AF | Thalamic input to parvalbumin-immunoreactive GABAergic interneurons: organization in normal striatum and effect of neonatal decortication. | 1999 | Neuroscience | pmid:10336127 |
| Nitsos I and Walker DW | Characterization of pontine neurons which respond to hypoxia in fetal sheep. | 1999 | Neurosci. Lett. | pmid:10336177 |
| Nielsen EO et al. | SPD 502: a water-soluble and in vivo long-lasting AMPA antagonist with neuroprotective activity. | 1999 | J. Pharmacol. Exp. Ther. | pmid:10336544 |
| Walsh LA et al. | Acute pentylenetetrazol injection reduces rat GABAA receptor mRNA levels and GABA stimulation of benzodiazepine binding with No effect on benzodiazepine binding site density. | 1999 | J. Pharmacol. Exp. Ther. | pmid:10336561 |
| Jourdain P et al. | Visualization of local afferent inputs to magnocellular oxytocin neurons in vitro. | 1999 | Eur. J. Neurosci. | pmid:10336665 |
| Manunta Y and Edeline JM | Effects of noradrenaline on frequency tuning of auditory cortex neurons during wakefulness and slow-wave sleep. | 1999 | Eur. J. Neurosci. | pmid:10336682 |
| Maxwell DJ and Riddell JS | Axoaxonic synapses on terminals of group II muscle spindle afferent axons in the spinal cord of the cat. | 1999 | Eur. J. Neurosci. | pmid:10336683 |
| Cunha RA and Ribeiro JA | Facilitation of GABA release by arachidonic acid in rat hippocampal synaptosomes. | 1999 | Eur. J. Neurosci. | pmid:10336686 |
| Eaton MJ et al. | Transplants of neuronal cells bioengineered to synthesize GABA alleviate chronic neuropathic pain. | 1999 Jan-Feb | Cell Transplant | pmid:10338278 |
| Davis AM et al. | Developmental sex differences in amino acid neurotransmitter levels in hypothalamic and limbic areas of rat brain. | 1999 | Neuroscience | pmid:10338313 |
| Boyce S et al. | Selective NMDA NR2B antagonists induce antinociception without motor dysfunction: correlation with restricted localisation of NR2B subunit in dorsal horn. | 1999 | Neuropharmacology | pmid:10340299 |
| Richter K et al. | Presynaptic cytomatrix protein bassoon is localized at both excitatory and inhibitory synapses of rat brain. | 1999 | J. Comp. Neurol. | pmid:10340516 |
| Zappulla JP et al. | Cloning and characterization of Aplysia neutral endopeptidase, a metallo-endopeptidase involved in the extracellular metabolism of neuropeptides in Aplysia californica. | 1999 | J. Neurosci. | pmid:10341232 |
| Katona I et al. | Presynaptically located CB1 cannabinoid receptors regulate GABA release from axon terminals of specific hippocampal interneurons. | 1999 | J. Neurosci. | pmid:10341254 |
| RodrÃguez M and González-Hernández T | Electrophysiological and morphological evidence for a GABAergic nigrostriatal pathway. | 1999 | J. Neurosci. | pmid:10341266 |
| Stutzmann GE and LeDoux JE | GABAergic antagonists block the inhibitory effects of serotonin in the lateral amygdala: a mechanism for modulation of sensory inputs related to fear conditioning. | 1999 | J. Neurosci. | pmid:10341269 |
| Beckman ML et al. | Multiple G protein-coupled receptors initiate protein kinase C redistribution of GABA transporters in hippocampal neurons. | 1999 | J. Neurosci. | pmid:10341270 |
| Guirado S and Dávila JC | GABAergic cell types in the lizard hippocampus. | 1999 | Eur J Morphol | pmid:10342435 |
| Doldán MJ et al. | Distribution of GABA-immunolabeling in the early zebrafish (Danio rerio) brain. | 1999 | Eur J Morphol | pmid:10342443 |
| Semiginovský B et al. | The cerebral GABA, beta-alanine, lysine and ethanolamine content and conversion of 14C from U 14C D glucose into their molecule during emotional stress in rats; effect of pyrithioxin and diazepam pretreatment. | 1976 | Act Nerv Super (Praha) | pmid:1034392 |
| Squires RF and Saederup E | Clozapine's antipsychotic effects do not depend on blockade of 5-HT3 receptors. | 1999 | Neurochem. Res. | pmid:10344595 |
| Pal S et al. | Neuropsychopharmacological profile of the methanolic fraction of Bryophyllum pinnatum leaf extract. | 1999 | J. Pharm. Pharmacol. | pmid:10344633 |
| Wegerhoff R | GABA and serotonin immunoreactivity during postembryonic brain development in the beetle Tenebrio molitor. | 1999 | Microsc. Res. Tech. | pmid:10344767 |
| Bicker G | Histochemistry of classical neurotransmitters in antennal lobes and mushroom bodies of the honeybee. | 1999 | Microsc. Res. Tech. | pmid:10344769 |
| Kurata Y et al. | Agonist and potentiation actions of n-octanol on gamma-aminobutyric acid type A receptors. | 1999 | Mol. Pharmacol. | pmid:10347242 |
| Ma D et al. | Simultaneous determination of gamma-aminobutyric acid and glutamic acid in the brain of 3-mercaptopropionic acid-treated rats using liquid chromatography-atmospheric pressure chemical ionization mass spectrometry. | 1999 | J. Chromatogr. B Biomed. Sci. Appl. | pmid:10348197 |
| Forray MI et al. | Noradrenaline inhibits glutamate release in the rat bed nucleus of the stria terminalis: in vivo microdialysis studies. | 1999 | J. Neurosci. Res. | pmid:10348662 |
| Tennison M | Focal lesion in the splenium of the corpus callosum in epileptic patients: antiepileptic drug toxicity? | 1999 | AJNR Am J Neuroradiol | pmid:10348730 |
| Dantzler WH and Silbernagl S | Renal tubular reabsorption of taurine, gamma-aminobutyric acid (GABA) and beta-alanine studied by continuous microperfusion. | 1976 | Pflugers Arch. | pmid:1034908 |
| Hattori A et al. | Bone morphogenetic protein-2 promotes survival and differentiation of striatal GABAergic neurons in the absence of glial cell proliferation. | 1999 | J. Neurochem. | pmid:10349834 |
| Bouzier AK et al. | [1-(13)C]glucose metabolism in the tumoral and nontumoral cerebral tissue of a glioma-bearing rat. | 1999 | J. Neurochem. | pmid:10349854 |
| Connaughton VP et al. | Immunocytochemical localization of excitatory and inhibitory neurotransmitters in the zebrafish retina. | 1999 May-Jun | Vis. Neurosci. | pmid:10349969 |
| Wassef AA et al. | Critical review of GABA-ergic drugs in the treatment of schizophrenia. | 1999 | J Clin Psychopharmacol | pmid:10350028 |
| pmid:10350162 | ||||
| Redecker P | Immunoreactivity for multiple GABA transporters (GAT-1, GAT-2, GAT-3) in the gerbil pineal gland. | 1999 | Neurosci. Lett. | pmid:10353341 |
| Sakai S and Tosaka T | Analysis of hyposmolarity-induced taurine efflux pathways in the bullfrog sympathetic ganglia. | 1999 | Neurochem. Int. | pmid:10355487 |
| Hasegawa K | [Changes in the substantia nigal self-stimulation behavior caused by intraventricular injection of norepinephrine, dopamine and GABA]. | 1976 | Nippon Yakurigaku Zasshi | pmid:1035566 |
| pmid:10356377 | ||||
| pmid:10356378 | ||||
| Gatzonis S et al. | A case of fever following antiepileptic treatment. | 1999 | Seizure | pmid:10356380 |
| Hamer HM and Morris HH | Successful treatment with gabapentin in the presence of hypersensitivity syndrome to phenytoin and carbamazepine: a report of three cases. | 1999 | Seizure | pmid:10356381 |
| Rite Gracia S et al. | [Non-ketotic hyperglycinemia: clinical and therapeutic course in three patients]. | 1999 | An. Esp. Pediatr. | pmid:10356838 |
| Van Rijn CM et al. | A molecular model for the synergic interaction between gamma-aminobutyric acid and general anaesthetics. | 1999 | Eur. J. Pharmacol. | pmid:10357259 |
| Stryker MP | Sensory maps on the move. | 1999 | Science | pmid:10357679 |
| Matskevitch I et al. | Functional characterization of the Betaine/gamma-aminobutyric acid transporter BGT-1 expressed in Xenopus oocytes. | 1999 | J. Biol. Chem. | pmid:10358010 |
| Jones GA et al. | Conduction velocities and membrane properties of different classes of rat septohippocampal neurons recorded in vitro. | 1999 | J. Physiol. (Lond.) | pmid:10358125 |
| Breitkreuz KE et al. | Identification and characterization of GABA, proline and quaternary ammonium compound transporters from Arabidopsis thaliana. | 1999 | FEBS Lett. | pmid:10359089 |
| Sun MK et al. | Calexcitin transformation of GABAergic synapses: from excitation filter to amplifier. | 1999 | Proc. Natl. Acad. Sci. U.S.A. | pmid:10359832 |
| Makara GB et al. | 3H-GABA uptake and acetylcholinesterase activity in dissociated cell cultures of the medial hypothalamus. | 1976 | Acta Biol Acad Sci Hung | pmid:1036000 |
| Behar KL et al. | Preliminary evidence of low cortical GABA levels in localized 1H-MR spectra of alcohol-dependent and hepatic encephalopathy patients. | 1999 | Am J Psychiatry | pmid:10360140 |
| Labbate LA and Rubey RN | Gabapentin-induced ejaculatory failure and anorgasmia. | 1999 | Am J Psychiatry | pmid:10360150 |
| Lovell RW | Mood stabilizer combinations for bipolar disorder. | 1999 | Am J Psychiatry | pmid:10360163 |
| Jiang Q and Li S | Rapid high-performance liquid chromatographic determination of serum gabapentin. | 1999 | J. Chromatogr. B Biomed. Sci. Appl. | pmid:10360430 |
| Tang PH et al. | Automated microanalysis of gabapentin in human serum by high-performance liquid chromatography with fluorometric detection. | 1999 | J. Chromatogr. B Biomed. Sci. Appl. | pmid:10360431 |
| Nishikawa K and Kidokoro Y | Halothane presynaptically depresses synaptic transmission in wild-type Drosophila larvae but not in halothane-resistant (har) mutants. | 1999 | Anesthesiology | pmid:10360868 |
| Pascual M et al. | Expression of neurotrophins in hippocampal interneurons immunoreactive for the neuropeptides somatostatin, neuropeptide-Y, vasoactive intestinal polypeptide and cholecystokinin. | 1999 | Neuroscience | pmid:10362297 |
| Consolo S et al. | Increased striatal expression of glutamate decarboxylase 67 after priming of 6-hydroxydopamine-lesioned rats. | 1999 | Neuroscience | pmid:10362306 |
| Kawai Y and Senba E | Electrophysiological and morphological characterization of cytochemically-defined neurons in the caudal nucleus of tractus solitarius of the rat. | 1999 | Neuroscience | pmid:10362319 |
| Hydén H et al. | Chloride permeation across the Deiters' neuron plasma membrane: activation by GABA on the membrane cytoplasmic side. | 1999 | Neuroscience | pmid:10362323 |