4-aminobutyric acid

4-aminobutyric acid is a lipid of Fatty Acyls (FA) class. 4-aminobutyric acid is associated with abnormalities such as Epilepsy and Premenstrual syndrome. The involved functions are known as Binding (Molecular Function), neuron survival, Process, Uptake and physiological aspects. 4-aminobutyric acid often locates in Microglial, Neurofilament, Neuraxis, Brain region and Neurites. The associated genes with 4-aminobutyric acid are arginine methyl ester, SLC33A1 gene, NKS1 gene, P4HTM gene and ITSN2 gene. The related lipids are pregnenolone sulfate, pregnane-20-one, Pregnanes, Steroids and endogenous steroids.

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Introduction

To understand associated biological information of 4-aminobutyric acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with 4-aminobutyric acid?

4-aminobutyric acid is suspected in Premenstrual syndrome, Epilepsy and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with 4-aminobutyric acid

MeSH term MeSH ID Detail
Acidosis, Lactic D000140 8 associated lipids
Adenocarcinoma D000230 166 associated lipids
Adenoma D000236 40 associated lipids
Adrenal Cortex Diseases D000303 1 associated lipids
Adrenoleukodystrophy D000326 29 associated lipids
Alcohol Amnestic Disorder D000425 2 associated lipids
Alcoholic Intoxication D000435 15 associated lipids
Alcoholism D000437 27 associated lipids
Alzheimer Disease D000544 76 associated lipids
Renal Aminoacidurias D000608 2 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with 4-aminobutyric acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with 4-aminobutyric acid?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with 4-aminobutyric acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with 4-aminobutyric acid?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with 4-aminobutyric acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with 4-aminobutyric acid?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with 4-aminobutyric acid

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Authors Title Published Journal PubMed Link
Stefanova N et al. Sex and age differences of neurons expressing GABA-immunoreactivity in the rat bed nucleus of the stria terminalis. 1998 Int. J. Dev. Neurosci. pmid:9881292
Szabat E et al. The ontogenic appearance of tyrosine hydroxylase-, serotonin-, gamma-aminobutyric acid-, calcitonin gene-related peptide-, substance P-, and synaptophysin-immunoreactivity in rat pituitary gland. 1998 Int. J. Dev. Neurosci. pmid:9881293
Gravielle MC et al. GABA-stimulated chloride uptake during avian CNS development: modulation by neurosteroids. 1998 Int. J. Dev. Neurosci. pmid:9881295
Hilbig H et al. Cytoarchitecture of the tectum opticum in the Japanese quail. 1998 Neuroscience pmid:9881878
Jouvenceau A et al. Alteration of NMDA receptor-mediated synaptic responses in CA1 area of the aged rat hippocampus: contribution of GABAergic and cholinergic deficits. 1998 Hippocampus pmid:9882020
Aistrup GL et al. Ethanol modulation of nicotinic acetylcholine receptor currents in cultured cortical neurons. 1999 Mol. Pharmacol. pmid:9882696
Neelands TR et al. Spontaneous and gamma-aminobutyric acid (GABA)-activated GABA(A) receptor channels formed by epsilon subunit-containing isoforms. 1999 Mol. Pharmacol. pmid:9882711
Bulfone A et al. An olfactory sensory map develops in the absence of normal projection neurons or GABAergic interneurons. 1998 Neuron pmid:9883721
Wilner AN New medication options for patients with epilepsy. 1998 Med Health R I pmid:9884541
Abi-Saab WM et al. 5-HT2 receptor regulation of extracellular GABA levels in the prefrontal cortex. 1999 Neuropsychopharmacology pmid:9885788