4-aminobutyric acid is a lipid of Fatty Acyls (FA) class. 4-aminobutyric acid is associated with abnormalities such as Epilepsy and Premenstrual syndrome. The involved functions are known as Binding (Molecular Function), neuron survival, Process, Uptake and physiological aspects. 4-aminobutyric acid often locates in Microglial, Neurofilament, Neuraxis, Brain region and Neurites. The associated genes with 4-aminobutyric acid are arginine methyl ester, SLC33A1 gene, NKS1 gene, P4HTM gene and ITSN2 gene. The related lipids are pregnenolone sulfate, pregnane-20-one, Pregnanes, Steroids and endogenous steroids.
To understand associated biological information of 4-aminobutyric acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
4-aminobutyric acid is suspected in Premenstrual syndrome, Epilepsy and other diseases in descending order of the highest number of associated sentences.
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We collected disease MeSH terms mapped to the references associated with 4-aminobutyric acid
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
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Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Gene | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Enna SJ et al. | Alterations of brain neurotransmitter receptor binding in Huntington's chorea. | 1976 | Brain Res. | pmid:10053 |
Bertrand S and Cazalets JR | Presynaptic GABAergic control of the locomotor drive in the isolated spinal cord of neonatal rats. | 1999 | Eur. J. Neurosci. | pmid:10051758 |
Marvizón JC et al. | Substance P release in the dorsal horn assessed by receptor internalization: NMDA receptors counteract a tonic inhibition by GABA(B) receptors. | 1999 | Eur. J. Neurosci. | pmid:10051742 |
Brünig I et al. | Dopamine receptor subtypes modulate olfactory bulb gamma-aminobutyric acid type A receptors. | 1999 | Proc. Natl. Acad. Sci. U.S.A. | pmid:10051664 |
Hansen SL et al. | Differential blockade of gamma-aminobutyric acid type A receptors by the neuroactive steroid dehydroepiandrosterone sulfate in posterior and intermediate pituitary. | 1999 | Mol. Pharmacol. | pmid:10051532 |
Amin J | A single hydrophobic residue confers barbiturate sensitivity to gamma-aminobutyric acid type C receptor. | 1999 | Mol. Pharmacol. | pmid:10051524 |
Wong AC et al. | D1- and D2-like dopamine receptors are co-localized on the presynaptic varicosities of striatal and nucleus accumbens neurons in vitro. | 1999 | Neuroscience | pmid:10051231 |
Arimatsu Y et al. | Area- and lamina-specific organization of a neuronal subpopulation defined by expression of latexin in the rat cerebral cortex. | 1999 | Neuroscience | pmid:10051192 |
Katona I et al. | Postsynaptic targets of somatostatin-immunoreactive interneurons in the rat hippocampus. | 1999 | Neuroscience | pmid:10051188 |
Zeng XJ and Tietz EI | Benzodiazepine tolerance at GABAergic synapses on hippocampal CA1 pyramidal cells. | 1999 | Synapse | pmid:10051107 |