4-aminobutyric acid

4-aminobutyric acid is a lipid of Fatty Acyls (FA) class. 4-aminobutyric acid is associated with abnormalities such as Epilepsy and Premenstrual syndrome. The involved functions are known as Binding (Molecular Function), neuron survival, Process, Uptake and physiological aspects. 4-aminobutyric acid often locates in Microglial, Neurofilament, Neuraxis, Brain region and Neurites. The associated genes with 4-aminobutyric acid are arginine methyl ester, SLC33A1 gene, NKS1 gene, P4HTM gene and ITSN2 gene. The related lipids are pregnenolone sulfate, pregnane-20-one, Pregnanes, Steroids and endogenous steroids.

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Introduction

To understand associated biological information of 4-aminobutyric acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with 4-aminobutyric acid?

4-aminobutyric acid is suspected in Premenstrual syndrome, Epilepsy and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with 4-aminobutyric acid

MeSH term MeSH ID Detail
Meningitis, Aseptic D008582 1 associated lipids
Gangliosidosis, GM1 D016537 1 associated lipids
Serotonin Syndrome D020230 1 associated lipids
Athetosis D001264 1 associated lipids
Syringomyelia D013595 1 associated lipids
Arachnoid Cysts D016080 1 associated lipids
Torticollis D014103 1 associated lipids
Meige Syndrome D008538 1 associated lipids
Carcinoma, Acinar Cell D018267 1 associated lipids
Meningitis, Viral D008587 1 associated lipids
alpha-Mannosidosis D008363 1 associated lipids
Hiccup D006606 1 associated lipids
Chorea D002819 1 associated lipids
Congenital Disorders of Glycosylation D018981 1 associated lipids
Tongue, Fissured D014063 1 associated lipids
Neuroectodermal Tumors, Primitive D018242 1 associated lipids
Polyradiculopathy D011128 1 associated lipids
Muscle Hypertonia D009122 1 associated lipids
Causalgia D002422 1 associated lipids
Iatrogenic Disease D007049 1 associated lipids
Vision, Low D015354 1 associated lipids
Presbycusis D011304 1 associated lipids
Dandy-Walker Syndrome D003616 1 associated lipids
Hypernatremia D006955 1 associated lipids
Nelson Syndrome D009347 1 associated lipids
Mitral Valve Prolapse D008945 1 associated lipids
Gigantism D005877 1 associated lipids
Hemifacial Spasm D019569 1 associated lipids
High Pressure Neurological Syndrome D006610 1 associated lipids
Hypophosphatasia D007014 1 associated lipids
Phantom Limb D010591 1 associated lipids
Dystonia Musculorum Deformans D004422 1 associated lipids
Angelman Syndrome D017204 1 associated lipids
Esotropia D004948 1 associated lipids
Choristoma D002828 1 associated lipids
Motion Sickness D009041 1 associated lipids
Tooth Abnormalities D014071 1 associated lipids
Arachnoiditis D001100 1 associated lipids
Adrenal Cortex Diseases D000303 1 associated lipids
Respiratory Paralysis D012133 1 associated lipids
Strabismus D013285 1 associated lipids
Bulbar Palsy, Progressive D010244 1 associated lipids
Cranial Nerve Diseases D003389 1 associated lipids
Epilepsy, Post-Traumatic D004834 1 associated lipids
Paraparesis D020335 1 associated lipids
Aphakia D001035 1 associated lipids
Illusions D007088 1 associated lipids
Somatostatinoma D013005 1 associated lipids
Tension-Type Headache D018781 1 associated lipids
Postpoliomyelitis Syndrome D016262 1 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with 4-aminobutyric acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with 4-aminobutyric acid?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with 4-aminobutyric acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with 4-aminobutyric acid?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with 4-aminobutyric acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with 4-aminobutyric acid?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with 4-aminobutyric acid

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Authors Title Published Journal PubMed Link
Tasker JG et al. Local glutamatergic and GABAergic synaptic circuits and metabotropic glutamate receptors in the hypothalamic paraventricular and supraoptic nuclei. 1998 Adv. Exp. Med. Biol. pmid:10026791
Thomas A and Amico JA Progesterone regulates hypothalamic oxytocin mRNA levels through gamma aminobutyric acid. 1998 Adv. Exp. Med. Biol. pmid:10026792
Wilke RA et al. Membrane excitability in the neurohypophysis. 1998 Adv. Exp. Med. Biol. pmid:10026805
Abe M and Matsuda M A correlation between changes in gamma-aminobutyric acid metabolism and seizures induced by antivitamin B6. 1976 J. Biochem. pmid:1002683
Pan HL et al. Gabapentin suppresses ectopic nerve discharges and reverses allodynia in neuropathic rats. 1999 J. Pharmacol. Exp. Ther. pmid:10027839
Nomura M et al. Novel characteristic for distinguishing Lactococcus lactis subsp. lactis from subsp. cremoris. 1999 Int. J. Syst. Bacteriol. pmid:10028257
Rocha ES et al. An analysis of low level doses of cholinesterase inhibitors in cultured neurons and hippocampal slices of rats. 1998 Drug Chem Toxicol pmid:10028411
Patte C et al. GABA inhibits endozepine release from cultured rat astrocytes. 1999 Glia pmid:10028922
Bird M and Owen A Neurite outgrowth-regulating properties of GABA and the effect of serum on mouse spinal cord neurons in culture. 1998 J. Anat. pmid:10029183
Renno WM et al. Quantitative immunoelectron microscopic colocalization of GABA and enkephalin in the ventrocaudal periaqueductal gray of the rat. 1999 Synapse pmid:10029240