4-aminobutyric acid is a lipid of Fatty Acyls (FA) class. 4-aminobutyric acid is associated with abnormalities such as Epilepsy and Premenstrual syndrome. The involved functions are known as Binding (Molecular Function), neuron survival, Process, Uptake and physiological aspects. 4-aminobutyric acid often locates in Microglial, Neurofilament, Neuraxis, Brain region and Neurites. The associated genes with 4-aminobutyric acid are arginine methyl ester, SLC33A1 gene, NKS1 gene, P4HTM gene and ITSN2 gene. The related lipids are pregnenolone sulfate, pregnane-20-one, Pregnanes, Steroids and endogenous steroids.
To understand associated biological information of 4-aminobutyric acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
4-aminobutyric acid is suspected in Premenstrual syndrome, Epilepsy and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
---|
We collected disease MeSH terms mapped to the references associated with 4-aminobutyric acid
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
---|
Function | Cross reference | Weighted score | Related literatures |
---|
Lipid concept | Cross reference | Weighted score | Related literatures |
---|
Gene | Cross reference | Weighted score | Related literatures |
---|
There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
---|---|---|---|---|
Cotrufo R and Bonavita V | [Neurochemical and pharmacological principles in the therapy of epilepsies]. | 1976 Mar-Apr | Acta Neurol (Napoli) | pmid:1007978 |
Subramanian P and Balamurugan E | Temporal oscillations of serum electrolytes in N-phthaloyl GABA-treated rats. | 1999 | Pharmacol. Biochem. Behav. | pmid:10080244 |
Zahner B et al. | Once-daily versus twice-daily vigabatrin: is there a difference? The results of a double-blind pilot study. | 1999 | Epilepsia | pmid:10080511 |
Bianchi L et al. | Simultaneous determination of basal and evoked output levels of aspartate, glutamate, taurine and 4-aminobutyric acid during microdialysis and from superfused brain slices. | 1999 | J. Chromatogr. B Biomed. Sci. Appl. | pmid:10080632 |
Skvortsova VI et al. | [Levels of neurotransmitter amino acids in the cerebrospinal fluid of patients with acute ischemic stroke]. | 1999 | Zh Nevrol Psikhiatr Im S S Korsakova | pmid:10081133 |
Meldrum B and Horton R | Blockade of epileptic responses in the photosensitive baboon, Papio papio, by two irreversible inhibitors of GABA-transaminase, gamma-acetylenic GABA (4-amino-hex-5-ynoic acid) and gamma-vinyl GABA (4-amino-hex-5-enoic acid). | 1978 | Psychopharmacology (Berl.) | pmid:100812 |
Kamardin N et al. | Distinct responses of osphradial neurons to chemical stimuli and neurotransmitters in Lymnaea stagnalis L. | 1999 | Cell. Mol. Neurobiol. | pmid:10081607 |
Honjo K et al. | GABA may function tonically via GABA(A) receptors to inhibit hypotension and bradycardia by L-DOPA microinjected into depressor sites of the nucleus tractus solitarii in anesthetized rats. | 1999 | Neurosci. Lett. | pmid:10081935 |
Goshima Y et al. | The evidence for tonic GABAergic regulation of basal L-DOPA release via activation of inhibitory GABA(A) receptors in the nucleus tractus solitarii of anesthetized rats. | 1999 | Neurosci. Lett. | pmid:10081972 |
Bloms-Funke P et al. | Extracellular single-unit recordings of piriform cortex neurons in rats: influence of different types of anesthesia and characterization of neurons by pharmacological manipulation of serotonin receptors. | 1999 | J. Neurosci. Res. | pmid:10082083 |