4-aminobutyric acid

4-aminobutyric acid is a lipid of Fatty Acyls (FA) class. 4-aminobutyric acid is associated with abnormalities such as Epilepsy and Premenstrual syndrome. The involved functions are known as Binding (Molecular Function), neuron survival, Process, Uptake and physiological aspects. 4-aminobutyric acid often locates in Microglial, Neurofilament, Neuraxis, Brain region and Neurites. The associated genes with 4-aminobutyric acid are arginine methyl ester, SLC33A1 gene, NKS1 gene, P4HTM gene and ITSN2 gene. The related lipids are pregnenolone sulfate, pregnane-20-one, Pregnanes, Steroids and endogenous steroids.

Cross Reference

Introduction

To understand associated biological information of 4-aminobutyric acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with 4-aminobutyric acid?

4-aminobutyric acid is suspected in Premenstrual syndrome, Epilepsy and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with 4-aminobutyric acid

MeSH term MeSH ID Detail
Hemolysis D006461 131 associated lipids
Uremia D014511 33 associated lipids
Stomach Ulcer D013276 75 associated lipids
Kidney Failure, Chronic D007676 51 associated lipids
Sarcoma, Experimental D012513 13 associated lipids
Arrhythmias, Cardiac D001145 42 associated lipids
Adenocarcinoma D000230 166 associated lipids
Pain D010146 64 associated lipids
Autoimmune Diseases D001327 27 associated lipids
Acidosis, Lactic D000140 8 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with 4-aminobutyric acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with 4-aminobutyric acid?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with 4-aminobutyric acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with 4-aminobutyric acid?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with 4-aminobutyric acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with 4-aminobutyric acid?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with 4-aminobutyric acid

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Authors Title Published Journal PubMed Link
Tasker JG et al. Local glutamatergic and GABAergic synaptic circuits and metabotropic glutamate receptors in the hypothalamic paraventricular and supraoptic nuclei. 1998 Adv. Exp. Med. Biol. pmid:10026791
Thomas A and Amico JA Progesterone regulates hypothalamic oxytocin mRNA levels through gamma aminobutyric acid. 1998 Adv. Exp. Med. Biol. pmid:10026792
Wilke RA et al. Membrane excitability in the neurohypophysis. 1998 Adv. Exp. Med. Biol. pmid:10026805
Abe M and Matsuda M A correlation between changes in gamma-aminobutyric acid metabolism and seizures induced by antivitamin B6. 1976 J. Biochem. pmid:1002683
Pan HL et al. Gabapentin suppresses ectopic nerve discharges and reverses allodynia in neuropathic rats. 1999 J. Pharmacol. Exp. Ther. pmid:10027839
Nomura M et al. Novel characteristic for distinguishing Lactococcus lactis subsp. lactis from subsp. cremoris. 1999 Int. J. Syst. Bacteriol. pmid:10028257
Rocha ES et al. An analysis of low level doses of cholinesterase inhibitors in cultured neurons and hippocampal slices of rats. 1998 Drug Chem Toxicol pmid:10028411
Patte C et al. GABA inhibits endozepine release from cultured rat astrocytes. 1999 Glia pmid:10028922
Bird M and Owen A Neurite outgrowth-regulating properties of GABA and the effect of serum on mouse spinal cord neurons in culture. 1998 J. Anat. pmid:10029183
Renno WM et al. Quantitative immunoelectron microscopic colocalization of GABA and enkephalin in the ventrocaudal periaqueductal gray of the rat. 1999 Synapse pmid:10029240