| MeSH term | MeSH ID | Detail |
|---|---|---|
| Hemolysis | D006461 | 131 associated lipids |
| Uremia | D014511 | 33 associated lipids |
| Stomach Ulcer | D013276 | 75 associated lipids |
| Kidney Failure, Chronic | D007676 | 51 associated lipids |
| Sarcoma, Experimental | D012513 | 13 associated lipids |
| Arrhythmias, Cardiac | D001145 | 42 associated lipids |
| Adenocarcinoma | D000230 | 166 associated lipids |
| Pain | D010146 | 64 associated lipids |
| Autoimmune Diseases | D001327 | 27 associated lipids |
| Acidosis, Lactic | D000140 | 8 associated lipids |
4-aminobutyric acid
4-aminobutyric acid is a lipid of Fatty Acyls (FA) class. 4-aminobutyric acid is associated with abnormalities such as Epilepsy and Premenstrual syndrome. The involved functions are known as Binding (Molecular Function), neuron survival, Process, Uptake and physiological aspects. 4-aminobutyric acid often locates in Microglial, Neurofilament, Neuraxis, Brain region and Neurites. The associated genes with 4-aminobutyric acid are arginine methyl ester, SLC33A1 gene, NKS1 gene, P4HTM gene and ITSN2 gene. The related lipids are pregnenolone sulfate, pregnane-20-one, Pregnanes, Steroids and endogenous steroids.
Cross Reference
Introduction
To understand associated biological information of 4-aminobutyric acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with 4-aminobutyric acid?
4-aminobutyric acid is suspected in Premenstrual syndrome, Epilepsy and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with 4-aminobutyric acid
PubChem Associated disorders and diseases
What pathways are associated with 4-aminobutyric acid
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with 4-aminobutyric acid?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with 4-aminobutyric acid?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with 4-aminobutyric acid?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
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What genes are associated with 4-aminobutyric acid?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with 4-aminobutyric acid?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with 4-aminobutyric acid
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Luca G et al. | Central and peripheral metabolic changes induced by gamma-hydroxybutyrate. | 2015 | Sleep | pmid:25515097 |
| Tao W et al. | Brainstem brain-derived neurotrophic factor signaling is required for histone deacetylase inhibitor-induced pain relief. | 2015 | Mol. Pharmacol. | pmid:25852071 |
| Cui SQ et al. | Puerarin protects against damage to spatial learning and memory ability in mice with chronic alcohol poisoning. | 2015 | Braz. J. Med. Biol. Res. | pmid:25831201 |
| Kardamakis AA et al. | Tectal microcircuit generating visual selection commands on gaze-controlling neurons. | 2015 | Proc. Natl. Acad. Sci. U.S.A. | pmid:25825743 |
| Alatorre A et al. | The local application of a flavonoid, (-)-epicatechin, increases the spiking of globus pallidus neurons in a dose-dependent manner and diminishes the catalepsy induced by haloperidol. | 2015 | Behav Pharmacol | pmid:25503260 |
| Yan X et al. | Activation of toll like receptor 4 attenuates GABA synthesis and postsynaptic GABA receptor activities in the spinal dorsal horn via releasing interleukin-1 beta. | 2015 | J Neuroinflammation | pmid:25571780 |
| Montserrat-de la Paz S et al. | Validation and additional support for an experimental animal model of fibromyalgia. | 2015 | Mod Rheumatol | pmid:24983406 |
| Brown AR et al. | Developmentally regulated neurosteroid synthesis enhances GABAergic neurotransmission in mouse thalamocortical neurones. | 2015 | J. Physiol. (Lond.) | pmid:25556800 |
| Sabaliauskas N et al. | Neurosteroid effects at α4βδ GABAA receptors alter spatial learning and synaptic plasticity in CA1 hippocampus across the estrous cycle of the mouse. | 2015 | Brain Res. | pmid:25542386 |
| Chen B et al. | Cosmetic side effects of antiepileptic drugs in adults with epilepsy. | 2015 | Epilepsy Behav | pmid:25513768 |
| Zhang Y et al. | Decreased carbon shunting from glucose toward oxidative metabolism in diet-induced ketotic rat brain. | 2015 | J. Neurochem. | pmid:25314677 |
| Mettang T and Kremer AE | Uremic pruritus. | 2015 | Kidney Int. | pmid:24402092 |
| Kumar A et al. | Hesperidin potentiates the neuroprotective effects of diazepam and gabapentin against pentylenetetrazole-induced convulsions in mice: Possible behavioral, biochemical and mitochondrial alterations. | 2014 May-Jun | Indian J Pharmacol | pmid:24987179 |
| Rizk NN et al. | Use of topical lidocaine, diphenhydramine hydrochloride, nystatin, and gabapentin swish in treatment for post-radiation neuropathy and oral mucositis. | 2014 May-Jun | Pain Physician | pmid:24850125 |
| Thompson AJ et al. | Phenylalanine in the pore of the Erwinia ligand-gated ion channel modulates picrotoxinin potency but not receptor function. | 2014 | Biochemistry | pmid:25238029 |
| Peng Q et al. | Activation of gab cluster transcription in Bacillus thuringiensis by γ-aminobutyric acid or succinic semialdehyde is mediated by the Sigma 54-dependent transcriptional activator GabR. | 2014 | BMC Microbiol. | pmid:25527261 |
| Kang YM et al. | Chronic infusion of enalaprilat into hypothalamic paraventricular nucleus attenuates angiotensin II-induced hypertension and cardiac hypertrophy by restoring neurotransmitters and cytokines. | 2014 | Toxicol. Appl. Pharmacol. | pmid:24342267 |
| Naito A et al. | Glycine and GABA(A) ultra-sensitive ethanol receptors as novel tools for alcohol and brain research. | 2014 | Mol. Pharmacol. | pmid:25245406 |
| Baniasadi M et al. | Effect of pregabalin augmentation in treatment of patients with combat-related chronic posttraumatic stress disorder: a randomized controlled trial. | 2014 | J Psychiatr Pract | pmid:25406046 |
| Gassel M et al. | The novel isoxazoline ectoparasiticide fluralaner: selective inhibition of arthropod γ-aminobutyric acid- and L-glutamate-gated chloride channels and insecticidal/acaricidal activity. | 2014 | Insect Biochem. Mol. Biol. | pmid:24365472 |