4-aminobutyric acid

4-aminobutyric acid is a lipid of Fatty Acyls (FA) class. 4-aminobutyric acid is associated with abnormalities such as Epilepsy and Premenstrual syndrome. The involved functions are known as Binding (Molecular Function), neuron survival, Process, Uptake and physiological aspects. 4-aminobutyric acid often locates in Microglial, Neurofilament, Neuraxis, Brain region and Neurites. The associated genes with 4-aminobutyric acid are arginine methyl ester, SLC33A1 gene, NKS1 gene, P4HTM gene and ITSN2 gene. The related lipids are pregnenolone sulfate, pregnane-20-one, Pregnanes, Steroids and endogenous steroids.

Cross Reference

Introduction

To understand associated biological information of 4-aminobutyric acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with 4-aminobutyric acid?

4-aminobutyric acid is suspected in Premenstrual syndrome, Epilepsy and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with 4-aminobutyric acid

MeSH term MeSH ID Detail
Hemolysis D006461 131 associated lipids
Uremia D014511 33 associated lipids
Stomach Ulcer D013276 75 associated lipids
Kidney Failure, Chronic D007676 51 associated lipids
Sarcoma, Experimental D012513 13 associated lipids
Arrhythmias, Cardiac D001145 42 associated lipids
Adenocarcinoma D000230 166 associated lipids
Pain D010146 64 associated lipids
Autoimmune Diseases D001327 27 associated lipids
Acidosis, Lactic D000140 8 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with 4-aminobutyric acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with 4-aminobutyric acid?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with 4-aminobutyric acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with 4-aminobutyric acid?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with 4-aminobutyric acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with 4-aminobutyric acid?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with 4-aminobutyric acid

Download all related citations
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Authors Title Published Journal PubMed Link
Ylinen A Antiepileptic efficacy of vigabatrin in people with severe epilepsy and intellectual disability. 1998 J Intellect Disabil Res pmid:10030432
Mikati MA et al. Gabapentin in the treatment of refractory partial epilepsy in children with intellectual disability. 1998 J Intellect Disabil Res pmid:10030434
Corrigall WA et al. Electrophysiological studies of fetal mouse olifactory bulb explants during development of synaptic functions in culture. 1976 J. Neurobiol. pmid:1003199
Perry TL and Hansen S Is GABA detectable in human CSF? 1976 J. Neurochem. pmid:1003229
Lodge D et al. The uptake of GABA and beta-alanine in slices of cat and rat CNS tissue: regional differences in susceptibility to inhibitors. 1976 J. Neurochem. pmid:1003233
Lake N and Voaden MJ Exchange versus net uptake of exogenously-applied gamma-aminobutyric acid in retina. 1976 J. Neurochem. pmid:1003234
Dumoulin A et al. Presence of the vesicular inhibitory amino acid transporter in GABAergic and glycinergic synaptic terminal boutons. 1999 J. Cell. Sci. pmid:10036231
Tredway TL et al. N-type voltage-dependent calcium channels mediate the nicotinic enhancement of GABA release in chick brain. 1999 J. Neurophysiol. pmid:10036250
Hirose N et al. Effects of propofol and fentanyl on extracellular levels of gamma-aminobutyric acid in the rat nucleus accumbens: an in vivo microdialysis study. 1998 J Oral Sci pmid:10036830
Sellstrom A et al. Functional assessment of GABA uptake or exchange by synaptosomal fractions. 1976 Nature pmid:1004608