4-aminobutyric acid

4-aminobutyric acid is a lipid of Fatty Acyls (FA) class. 4-aminobutyric acid is associated with abnormalities such as Epilepsy and Premenstrual syndrome. The involved functions are known as Binding (Molecular Function), neuron survival, Process, Uptake and physiological aspects. 4-aminobutyric acid often locates in Microglial, Neurofilament, Neuraxis, Brain region and Neurites. The associated genes with 4-aminobutyric acid are arginine methyl ester, SLC33A1 gene, NKS1 gene, P4HTM gene and ITSN2 gene. The related lipids are pregnenolone sulfate, pregnane-20-one, Pregnanes, Steroids and endogenous steroids.

Cross Reference

Introduction

To understand associated biological information of 4-aminobutyric acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with 4-aminobutyric acid?

4-aminobutyric acid is suspected in Premenstrual syndrome, Epilepsy and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
Loading... please refresh the page if content is not showing up.

Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with 4-aminobutyric acid

MeSH term MeSH ID Detail
Hemolysis D006461 131 associated lipids
Uremia D014511 33 associated lipids
Stomach Ulcer D013276 75 associated lipids
Kidney Failure, Chronic D007676 51 associated lipids
Sarcoma, Experimental D012513 13 associated lipids
Arrhythmias, Cardiac D001145 42 associated lipids
Adenocarcinoma D000230 166 associated lipids
Pain D010146 64 associated lipids
Autoimmune Diseases D001327 27 associated lipids
Acidosis, Lactic D000140 8 associated lipids
Per page 10 20 50 100 | Total 280

PubChem Associated disorders and diseases

What pathways are associated with 4-aminobutyric acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with 4-aminobutyric acid?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
Loading... please refresh the page if content is not showing up.

What functions are associated with 4-aminobutyric acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with 4-aminobutyric acid?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
Loading... please refresh the page if content is not showing up.

What genes are associated with 4-aminobutyric acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with 4-aminobutyric acid?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with 4-aminobutyric acid

Download all related citations
Per page 10 20 50 100 | Total 40318
Authors Title Published Journal PubMed Link
Baumann K et al. The impact of oxygen on the transcriptome of recombinant S. cerevisiae and P. pastoris - a comparative analysis. 2011 BMC Genomics pmid:21554735
Zappettini S et al. Presynaptic nicotinic α7 and non-α7 receptors stimulate endogenous GABA release from rat hippocampal synaptosomes through two mechanisms of action. 2011 PLoS ONE pmid:21346795
Conti F et al. A Role for GAT-1 in Presynaptic GABA Homeostasis? 2011 Front Cell Neurosci pmid:21503156
Siggberg L et al. Familial 6p22.2 duplication associates with mild developmental delay and increased SSADH activity. 2011 Am. J. Med. Genet. B Neuropsychiatr. Genet. pmid:21438145
Guo M et al. The bZIP transcription factor MoAP1 mediates the oxidative stress response and is critical for pathogenicity of the rice blast fungus Magnaporthe oryzae. 2011 PLoS Pathog. pmid:21383978
Clausen CA et al. The role of particle size of particulate nano-zinc oxide wood preservatives on termite mortality and leach resistance. 2011 Nanoscale Res Lett pmid:21711491
Yan B and Li P An integrative view of mechanisms underlying generalized spike-and-wave epileptic seizures and its implication on optimal therapeutic treatments. 2011 PLoS ONE pmid:21811612
Schlüter A et al. Phylogenomic evidence for a myxococcal contribution to the mitochondrial fatty acid beta-oxidation. 2011 PLoS ONE pmid:21760940
Brams M et al. A structural and mutagenic blueprint for molecular recognition of strychnine and d-tubocurarine by different cys-loop receptors. 2011 PLoS Biol. pmid:21468359
Cardoso N et al. Probable gamma-aminobutyric acid involvement in bisphenol A effect at the hypothalamic level in adult male rats. 2011 J. Physiol. Biochem. pmid:21656274
Kammerer M et al. Effects of antiepileptic drugs on GABA release from rat and human neocortical synaptosomes. 2011 Naunyn Schmiedebergs Arch. Pharmacol. pmid:21533993
Simeone TA et al. cAMP-dependent protein kinase A activity modulates topiramate potentiation of GABA(A) receptors. 2011 Epilepsy Res. pmid:21665439
Görbitz CH Solid-state phase transitions in DL-norvaline studied by single-crystal X-ray diffraction. 2011 J Phys Chem B pmid:21332110
Coyne L et al. Neuropharmacological properties of neurons derived from human stem cells. 2011 Neurochem. Int. pmid:21315124
Hill MN et al. Recruitment of prefrontal cortical endocannabinoid signaling by glucocorticoids contributes to termination of the stress response. 2011 J. Neurosci. pmid:21775596
Toyokura K et al. Succinic semialdehyde dehydrogenase is involved in the robust patterning of Arabidopsis leaves along the adaxial-abaxial axis. 2011 Plant Cell Physiol. pmid:21690177
Tanabe K et al. Midazolam suppresses interleukin-1β-induced interleukin-6 release from rat glial cells. 2011 J Neuroinflammation pmid:21682888
Yahr P Sex difference and response to testosterone in gabaergic cells of the medial preoptic nucleus and ventral bed nuclei of the stria terminalis in gerbils. 2011 Horm Behav pmid:21281643
de Carvalho LP et al. On the chemical mechanism of succinic semialdehyde dehydrogenase (GabD1) from Mycobacterium tuberculosis. 2011 Arch. Biochem. Biophys. pmid:21303655
Alabed S et al. Gamma-aminobutyric acid agonists for neuroleptic-induced tardive dyskinesia. 2011 Cochrane Database Syst Rev pmid:21491376
Grassl J et al. Matrix-assisted laser desorption/ionisation mass spectrometry imaging and its development for plant protein imaging. 2011 Plant Methods pmid:21726462
Rosell A et al. Brain perihematoma genomic profile following spontaneous human intracerebral hemorrhage. 2011 PLoS ONE pmid:21311749
Kanner AM Are antiepileptic drugs used in the treatment of migraine associated with an increased risk of suicidality? 2011 Curr Pain Headache Rep pmid:21479999
Pizzolato R et al. Efficacy and tolerability of pregabalin as preventive treatment for migraine: a 3-month follow-up study. 2011 J Headache Pain pmid:21479703
Ponnusamy K et al. Microbial community and metabolomic comparison of irritable bowel syndrome faeces. 2011 J. Med. Microbiol. pmid:21330412
Cauli O et al. Differential modulation of the glutamate-nitric oxide-cyclic GMP pathway by distinct neurosteroids in cerebellum in vivo. 2011 Neuroscience pmid:21703332
Gehman LT et al. The splicing regulator Rbfox1 (A2BP1) controls neuronal excitation in the mammalian brain. 2011 Nat. Genet. pmid:21623373
Jacobson SA and Sabbagh MN Investigational drugs for the treatment of AD: what can we learn from negative trials? 2011 Alzheimers Res Ther pmid:21539725
Singh P et al. Transcriptomic analysis in a Drosophila model identifies previously implicated and novel pathways in the therapeutic mechanism in neuropsychiatric disorders. 2011 Front Neurosci pmid:21503142
Xiao X et al. Exploring metabolic pathway disruption in the subchronic phencyclidine model of schizophrenia with the Generalized Singular Value Decomposition. 2011 BMC Syst Biol pmid:21575198
Vicini S The FGIN period: electrophysiological studies. 2011 Pharmacol. Res. pmid:21704166
Li YX et al. Modulation of the assay system for the sensory integration of 2 sensory stimuli that inhibit each other in nematode Caenorhabditis elegans. 2011 Neurosci Bull pmid:21441968
Pizzarelli R and Cherubini E Alterations of GABAergic signaling in autism spectrum disorders. 2011 Neural Plast. pmid:21766041
Baroncelli L et al. Brain plasticity and disease: a matter of inhibition. 2011 Neural Plast. pmid:21766040
Chattopadhyaya B Molecular mechanisms underlying activity-dependent GABAergic synapse development and plasticity and its implications for neurodevelopmental disorders. 2011 Neural Plast. pmid:21826279
Zhang D et al. Microglial MAC1 receptor and PI3K are essential in mediating β-amyloid peptide-induced microglial activation and subsequent neurotoxicity. 2011 J Neuroinflammation pmid:21232086
Hofmann ME et al. Cannabinoid receptor agonists potentiate action potential-independent release of GABA in the dentate gyrus through a CB1 receptor-independent mechanism. 2011 J. Physiol. (Lond.) pmid:21646412
Perret A et al. A novel acyl-CoA beta-transaminase characterized from a metagenome. 2011 PLoS ONE pmid:21826218
Nakamura S and Ohtsubo K Acceleration of germination of super-hard rice cultivar EM10 by soaking with red onion. 2011 Biosci. Biotechnol. Biochem. pmid:21389608
Beaumont M and Maccaferri G Is connexin36 critical for GABAergic hypersynchronization in the hippocampus? 2011 J. Physiol. (Lond.) pmid:21300748
Yakoot M et al. Pilot study of the efficacy and safety of lettuce seed oil in patients with sleep disorders. 2011 Int J Gen Med pmid:21731897
Smith HS et al. Pharmacotherapy for fibromyalgia. 2011 Front Pharmacol pmid:21772818
Wolkowitz OM et al. Of sound mind and body: depression, disease, and accelerated aging. 2011 Dialogues Clin Neurosci pmid:21485744
Cantarín-Extremera V et al. [Clinical, electroencephalographic and genomic characteristics of patients with epilepsy with febrile seizures plus]. 2011 Rev Neurol pmid:21425109
Jiménez-González C et al. Non-neuronal, slow GABA signalling in the ventrobasal thalamus targets δ-subunit-containing GABA(A) receptors. 2011 Eur. J. Neurosci. pmid:21395866
Kortleven C et al. The endocannabinoid 2-arachidonoylglycerol inhibits long-term potentiation of glutamatergic synapses onto ventral tegmental area dopamine neurons in mice. 2011 Eur. J. Neurosci. pmid:21410793
Bubar MJ et al. 5-HT(2C) receptors localize to dopamine and GABA neurons in the rat mesoaccumbens pathway. 2011 PLoS ONE pmid:21687728
Rojas DC et al. Transient and steady-state auditory gamma-band responses in first-degree relatives of people with autism spectrum disorder. 2011 Mol Autism pmid:21729257
Chu LC et al. Chronic intrathecal infusion of gabapentin prevents nerve ligation-induced pain in rats. 2011 Br J Anaesth pmid:21441243
Pearl PL et al. Epilepsy in succinic semialdehyde dehydrogenase deficiency, a disorder of GABA metabolism. 2011 Brain Dev. pmid:21664777
Lund TM et al. β-Hydroxybutyrate is the preferred substrate for GABA and glutamate synthesis while glucose is indispensable during depolarization in cultured GABAergic neurons. 2011 Neurochem. Int. pmid:21684314
Jia P et al. Prioritization of epilepsy associated candidate genes by convergent analysis. 2011 PLoS ONE pmid:21390307
Goldkamp J et al. Stiff person syndrome and pregnancy. 2011 Obstet Gynecol pmid:21768852
Kalhoefer D et al. Comparative genome analysis and genome-guided physiological analysis of Roseobacter litoralis. 2011 BMC Genomics pmid:21693016
El-Ansary AK et al. Plasma fatty acids as diagnostic markers in autistic patients from Saudi Arabia. 2011 Lipids Health Dis pmid:21510882
Vijayalakshmi A et al. Anticonvulsant and neurotoxicity profile of the rhizome of Smilax china Linn. in mice. 2011 Indian J Pharmacol pmid:21455417
Störtkuhl KF and Fiala A The Smell of Blue Light: A New Approach toward Understanding an Olfactory Neuronal Network. 2011 Front Neurosci pmid:21647413
Zschenderlein C et al. Capsaicin-induced changes in LTP in the lateral amygdala are mediated by TRPV1. 2011 PLoS ONE pmid:21249195
Ivanov A et al. Lactate Effectively Covers Energy Demands during Neuronal Network Activity in Neonatal Hippocampal Slices. 2011 Front Neuroenergetics pmid:21602909
Murphy TM et al. Risk and protective genetic variants in suicidal behaviour: association with SLC1A2, SLC1A3, 5-HTR1B &NTRK2 polymorphisms. 2011 Behav Brain Funct pmid:21711518
Sanna E et al. Voluntary Ethanol Consumption Induced by Social Isolation Reverses the Increase of α(4)/δ GABA(A) Receptor Gene Expression and Function in the Hippocampus of C57BL/6J Mice. 2011 Front Neurosci pmid:21347217
Manolakos E et al. Combined 22q11.1-q11.21 deletion with 15q11.2-q13.3 duplication identified by array-CGH in a 6 years old boy. 2011 Mol Cytogenet pmid:21345209
Ha KY et al. Pregabalin as a neuroprotector after spinal cord injury in rats: biochemical analysis and effect on glial cells. 2011 J. Korean Med. Sci. pmid:21394310
Shirmardi SP et al. Preclinical evaluation of a new bombesin analog for imaging of gastrin-releasing peptide receptors. 2011 Cancer Biother. Radiopharm. pmid:21711115
Zaugg J et al. Identification and characterization of GABA(A) receptor modulatory diterpenes from Biota orientalis that decrease locomotor activity in mice. 2011 J. Nat. Prod. pmid:21793559
Kanehira T et al. Relieving occupational fatigue by consumption of a beverage containing γ-amino butyric acid. 2011 J. Nutr. Sci. Vitaminol. pmid:21512285
Chatzi C et al. Retinoic acid functions as a key GABAergic differentiation signal in the basal ganglia. 2011 PLoS Biol. pmid:21532733
Calderón Guzmán D et al. Effect of flutamide and two novel synthetic steroids on GABA, glutamine and some oxidative stress markers in rat brain and prostate. 2011 Andrologia pmid:21486400
Flores A et al. Acute effects of unilateral sectioning the superior ovarian nerve of rats with unilateral ovariectomy on ovarian hormones (progesterone, testosterone and estradiol) levels vary during the estrous cycle. 2011 Reprod. Biol. Endocrinol. pmid:21414235
Wang Z et al. Progesterone administration modulates cortical TLR4/NF-κB signaling pathway after subarachnoid hemorrhage in male rats. 2011 Mediators Inflamm. pmid:21403869
Francke C et al. Comparative analyses imply that the enigmatic Sigma factor 54 is a central controller of the bacterial exterior. 2011 BMC Genomics pmid:21806785
Muthuraman A and Singh N Attenuating effect of Acorus calamus extract in chronic constriction injury induced neuropathic pain in rats: an evidence of anti-oxidative, anti-inflammatory, neuroprotective and calcium inhibitory effects. 2011 BMC Complement Altern Med pmid:21426568
Young RL Sensing via intestinal sweet taste pathways. 2011 Front Neurosci pmid:21519398
Murgatroyd C and Spengler D Epigenetics of early child development. 2011 Front Psychiatry pmid:21647402
Hosoda K et al. Cooperative adaptation to establishment of a synthetic bacterial mutualism. 2011 PLoS ONE pmid:21359225
Bittner S et al. [Pregabalin and gabapentin in multiple sclerosis: clinical experiences and therapeutic implications]. 2011 Nervenarzt pmid:21647743
Jo JY et al. Neurosteroid modulation of benzodiazepine-sensitive GABAA tonic inhibition in supraoptic magnocellular neurons. 2011 Am. J. Physiol. Regul. Integr. Comp. Physiol. pmid:21451144
Tachikawa M and Hosoya K Transport characteristics of guanidino compounds at the blood-brain barrier and blood-cerebrospinal fluid barrier: relevance to neural disorders. 2011 Fluids Barriers CNS pmid:21352605
Thwaites DT and Anderson CM The SLC36 family of proton-coupled amino acid transporters and their potential role in drug transport. 2011 Br. J. Pharmacol. pmid:21501141
Araújo WL et al. Antisense inhibition of the iron-sulphur subunit of succinate dehydrogenase enhances photosynthesis and growth in tomato via an organic acid-mediated effect on stomatal aperture. 2011 Plant Cell pmid:21307286
Bockbrader HN et al. Pregabalin effect on steady-state pharmacokinetics of carbamazepine, lamotrigine, phenobarbital, phenytoin, topiramate, valproate, and tiagabine. 2011 Epilepsia pmid:21314678
Murase S et al. In the newborn hippocampus, neurotrophin-dependent survival requires spontaneous activity and integrin signaling. 2011 J. Neurosci. pmid:21613492
Margalit E et al. Inner and outer retinal mechanisms engaged by epiretinal stimulation in normal and rd mice. 2011 Vis. Neurosci. pmid:21463541
Lacouture ME et al. Clinical practice guidelines for the prevention and treatment of EGFR inhibitor-associated dermatologic toxicities. 2011 Support Care Cancer pmid:21630130
Béracochéa D et al. Interaction between Diazepam and Hippocampal Corticosterone after Acute Stress: Impact on Memory in Middle-Aged Mice. 2011 Front Behav Neurosci pmid:21516247
Ghosh A et al. Newer molecules in the treatment of schizophrenia: A clinical update. 2011 Indian J Pharmacol pmid:21572641
Pey J et al. Path finding methods accounting for stoichiometry in metabolic networks. 2011 Genome Biol. pmid:21619601
Dykman LA and Khlebtsov NG Gold nanoparticles in biology and medicine: recent advances and prospects. 2011 Acta Naturae pmid:22649683
Frye RE et al. Traditional and non-traditional treatments for autism spectrum disorder with seizures: an on-line survey. 2011 BMC Pediatr pmid:21592359
Yang ZZ et al. Effect of ginkgolide B on striatal extracellular amino acids in middle cerebral artery occluded rats. 2011 J Ethnopharmacol pmid:21527331
Vylkova S et al. The fungal pathogen Candida albicans autoinduces hyphal morphogenesis by raising extracellular pH. 2011 MBio pmid:21586647
Cui YF et al. Embryonic stem cell-derived L1 overexpressing neural aggregates enhance recovery after spinal cord injury in mice. 2011 PLoS ONE pmid:21445247
Bonin RP et al. Pharmacological enhancement of δ-subunit-containing GABA(A) receptors that generate a tonic inhibitory conductance in spinal neurons attenuates acute nociception in mice. 2011 Pain pmid:21396779
Chtourou Y et al. Manganese induces oxidative stress, redox state unbalance and disrupts membrane bound ATPases on murine neuroblastoma cells in vitro: protective role of silymarin. 2011 Neurochem. Res. pmid:21533646
Porcu P et al. Genetic analysis of the neurosteroid deoxycorticosterone and its relation to alcohol phenotypes: identification of QTLs and downstream gene regulation. 2011 PLoS ONE pmid:21494628
Kaplan GB and Moore KA The use of cognitive enhancers in animal models of fear extinction. 2011 Pharmacol. Biochem. Behav. pmid:21256147
Zhou JQ et al. Analyzing clinical and electrophysiological characteristics of Paroxysmal Dyskinesia. 2011 J Res Med Sci pmid:21448393
Therisa KK and Desai PV Study of epileptiform activity in cerebral ganglion of mud crab Scylla serrata. 2011 Invert. Neurosci. pmid:21249512
Yang H et al. Comparison of metabolic profiling of cyanidin-3-O-galactoside and extracts from blueberry in aged mice. 2011 J. Agric. Food Chem. pmid:21302942
Cuzon Carlson VC et al. Synaptic and morphological neuroadaptations in the putamen associated with long-term, relapsing alcohol drinking in primates. 2011 Neuropsychopharmacology pmid:21796110