L-norvaline is a lipid of Fatty Acyls (FA) class. L-norvaline is associated with abnormalities such as Celiac Disease, Exanthema, Atherosclerosis, Plasmodium falciparum infection and Parasitemia. The involved functions are known as Anabolism, Saturated, Stimulus, Physiologic Organization and arginase activity. L-norvaline often locates in Extracellular, Protoplasm, soluble, viral nucleocapsid location and Cell Wall. The associated genes with L-norvaline are norvaline, Amino Acids, Basic, ARG1 gene, Escherichia coli Proteins and Operon. The related lipids are Lipopolysaccharides.
To understand associated biological information of L-norvaline, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
L-norvaline is suspected in Exanthema, Parasitemia, Celiac Disease, Atherosclerosis, Plasmodium falciparum infection and other diseases in descending order of the highest number of associated sentences.
| Disease | Cross reference | Weighted score | Related literature |
|---|
We collected disease MeSH terms mapped to the references associated with L-norvaline
| MeSH term | MeSH ID | Detail |
|---|---|---|
| Marek Disease | D008380 | 4 associated lipids |
| Celiac Disease | D002446 | 16 associated lipids |
| Kidney Diseases | D007674 | 29 associated lipids |
| Metabolic Syndrome | D024821 | 44 associated lipids |
| Liver Neoplasms, Experimental | D008114 | 46 associated lipids |
| Diabetes Mellitus, Experimental | D003921 | 85 associated lipids |
| Carcinoma, Hepatocellular | D006528 | 140 associated lipids |
| Adenocarcinoma | D000230 | 166 associated lipids |
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
| Location | Cross reference | Weighted score | Related literatures |
|---|
| Function | Cross reference | Weighted score | Related literatures |
|---|
| Lipid concept | Cross reference | Weighted score | Related literatures |
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| Gene | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| pmid:20512454 | ||||
| pmid:19489061 | ||||
| pmid:19248796 | ||||
| pmid:19156318 | ||||
| pmid:26857261 | ||||
| pmid:26671005 | ||||
| pmid:26146397 | ||||
| pmid:25841644 | ||||
| pmid:25794326 | ||||
| pmid:25542213 | ||||
| pmid:25251725 | ||||
| pmid:14404270 | ||||
| pmid:25695622 | ||||
| pmid:25267157 | ||||
| pmid:12997134 | ||||
| pmid:15053781 | ||||
| pmid: | ||||
| WELKER NE and CAMPBELL LL | DE NOVO SYNTHESIS OF ALPHA-AMYLASE BY BACILLUS STEAROTHERMOPHILUS. | 1963 | J. Bacteriol. | pmid:14086090 |
| HUNT DE | AMINO ACIDS AS PROTECTIVE COMPOUNDS IN ULTRAVIOLET-IRRADIATED HANSENULA WINGEI. | 1964 | J. Bacteriol. | pmid:14219051 |
| CABELLO J et al. | MOLECULAR CHANGES DURING THE TITRATION OF ALPHA-KETO-DELTA-AMINOVALERIC ACID. | 1964 | Arch. Biochem. Biophys. | pmid:14211565 |
| Marshall M and Cohen PP | Ornithine transcarbamylase from Streptococcus faecalis and bovine liver. II. Multiple binding sites for carbamyl-P and L-norvaline, correlation with steady state kinetics. | 1972 | J. Biol. Chem. | pmid:4622304 |
| Nandi PK | Thermodynamic parameters of transfer of N-acetyl ethyl esters of different amino acids from organic solvents to water. | 1976 | Int. J. Pept. Protein Res. | pmid:1279082 |
| KasafÃrek E et al. | p-Nitroanilides of 3-carboxypropionyl-peptides. Their cleavage by elastase, trypsin, and chymotrypsin. | 1976 | Eur. J. Biochem. | pmid:991849 |
| Arola L et al. | Determination of plasma amino acids in small samples with the use of Dansyl-chloride. | 1976 | Biochimie | pmid:1009175 |
| Vajda T and Szabó T | Specificity of trypsin and alpha-chymotrypsin towards neutral substrates. | 1976 | Acta Biochim. Biophys. Acad. Sci. Hung. | pmid:1026004 |
| Kisumi M et al. | L-Norvaline and L-homoisoleucine formation by Serratia marcescens,. | 1976 | J. Biochem. | pmid:783153 |
| Hinz HJ et al. | Thermodynamic studies on the specificity of L-isoleucine-tRNA ligase of Escherichia coli MRE 600. Calorimetric investigations on binding of amino acids and isoleucinol to the enzyme. | 1976 | Eur. J. Biochem. | pmid:795668 |
| Rognstad R | Sources of ammonia for urea synthesis in isolated rat liver cells. | 1977 | Biochim. Biophys. Acta | pmid:836898 |
| Young JD and Ellory JC | Substrate specificity of amino acid transport in sheep erythrocytes. | 1977 | Biochem. J. | pmid:849280 |
| Nishizawa R et al. | Synthesis and structure-activity relationships of bestatin analogues, inhibitors of aminopeptidase B. | 1977 | J. Med. Chem. | pmid:850237 |
| Pausch J et al. | Protective effect of ammonium ions and L-norvaline on galactosamine induced liver injury. | 1977 | Hoppe-Seyler's Z. Physiol. Chem. | pmid:881166 |
| Pierson DL et al. | Human ornithine transcarbamylase. Purification and characterization of the enzyme from normal liver and the liver of a Reye's syndrome patient. | 1977 | J. Biol. Chem. | pmid:893420 |
| Ivanov CP and Slavcheva NN | Formation of amino acids on heating glycine with alumina. | 1977 | Orig. Life | pmid:896188 |
| Naoi M et al. | Permeability of amino acids into liposomes. | 1977 | Biochim. Biophys. Acta | pmid:21692 |
| Ohshima T et al. | Properties of crystalline leucine dehydrogenase from Bacillus sphaericus. | 1978 | J. Biol. Chem. | pmid:670223 |
| Prokopenko VM et al. | [Biological properties of the modified actinomycins synthesized by the aurantin producer]. | 1978 | Antibiotiki | pmid:75711 |
| Takada S et al. | Studies on rat liver argininosuccinate synthetase. Inhibition by various amino acids. | 1979 | J. Biochem. | pmid:447618 |
| Saheki T et al. | Regulation of urea synthesis in rat liver. Inhibition of urea synthesis by L-norvaline. | 1979 | J. Biochem. | pmid:511845 |
| Rife JE and Cleland WW | Kinetic mechanism of glutamate dehydrogenase. | 1980 | Biochemistry | pmid:7190024 |
| Rife JE and Cleland WW | Determination of the chemical mechanism of glutamate dehydrogenase from pH studies. | 1980 | Biochemistry | pmid:7190025 |
| Marshall M and Cohen PP | Evidence for an exceptionally reactive arginyl residue at the binding site for carbamyl phosphate in bovine ornithine transcarbamylase. | 1980 | J. Biol. Chem. | pmid:7391082 |
| Kazarinoff MN and Snell EE | Some effects of indole on the interaction of amino acids with tryptophanase. | 1980 | J. Biol. Chem. | pmid:6993468 |
| Del Mar EG et al. | Substrate specificity of human pancreatic elastase 2. | 1980 | Biochemistry | pmid:6898442 |
| BelitskiÄ BR and Shakulov RS | [Guanosine polyphosphate concentration and stable RNA synthesis in Bacillus subtilis following suppression of protein synthesis]. | 1980 Nov-Dec | Mol. Biol. (Mosk.) | pmid:6160384 |
| Fortin AF et al. | Comparison of the essential arginine residue in Escherichia coli ornithine and aspartate transcarbamylases. | 1981 | Biochim. Biophys. Acta | pmid:7030401 |
| Weber AL and Miller SL | Reasons for the occurrence of the twenty coded protein amino acids. | 1981 | J. Mol. Evol. | pmid:7277510 |
| Grinde B and Seglen PO | Effects of amino acid analogues on protein degradation in isolated rat hepatocytes. | 1981 | Biochim. Biophys. Acta | pmid:7260111 |
| Sugiura M et al. | beta-methylnorleucine, an antimetabolite produced by Serratia marcescens. | 1981 | J. Antibiot. | pmid:7031030 |
| Sener A et al. | The stimulus-secretion coupling of amino acid-induced insulin release. Biosynthetic and secretory responses of rat pancreatic islet to L-leucine and L-glutamine. | 1981 | Diabetologia | pmid:7021285 |
| Malaisse WJ et al. | The stimulus-secretion coupling of amino acid-induced insulin release. IV. Ionic response to L-Leucine and L-Glutamine. | 1981 | Pflugers Arch. | pmid:7027175 |