L-norvaline is a lipid of Fatty Acyls (FA) class. L-norvaline is associated with abnormalities such as Celiac Disease, Exanthema, Atherosclerosis, Plasmodium falciparum infection and Parasitemia. The involved functions are known as Anabolism, Saturated, Stimulus, Physiologic Organization and arginase activity. L-norvaline often locates in Extracellular, Protoplasm, soluble, viral nucleocapsid location and Cell Wall. The associated genes with L-norvaline are norvaline, Amino Acids, Basic, ARG1 gene, Escherichia coli Proteins and Operon. The related lipids are Lipopolysaccharides.
To understand associated biological information of L-norvaline, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
L-norvaline is suspected in Exanthema, Parasitemia, Celiac Disease, Atherosclerosis, Plasmodium falciparum infection and other diseases in descending order of the highest number of associated sentences.
| Disease | Cross reference | Weighted score | Related literature |
|---|
We collected disease MeSH terms mapped to the references associated with L-norvaline
| MeSH term | MeSH ID | Detail |
|---|---|---|
| Adenocarcinoma | D000230 | 166 associated lipids |
| Carcinoma, Hepatocellular | D006528 | 140 associated lipids |
| Diabetes Mellitus, Experimental | D003921 | 85 associated lipids |
| Liver Neoplasms, Experimental | D008114 | 46 associated lipids |
| Metabolic Syndrome | D024821 | 44 associated lipids |
| Kidney Diseases | D007674 | 29 associated lipids |
| Celiac Disease | D002446 | 16 associated lipids |
| Marek Disease | D008380 | 4 associated lipids |
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
| Location | Cross reference | Weighted score | Related literatures |
|---|
| Function | Cross reference | Weighted score | Related literatures |
|---|
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
| Gene | Cross reference | Weighted score | Related literatures |
|---|
There are no associated biomedical information in the current reference collection.
| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
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| Ohba S et al. | [On the biosynthesis of guanidinosuccinic acid in rat liver. Effect of urea, ornithine and D, L-norvaline]. | 1982 | Nihon Jinzo Gakkai Shi | pmid:7161946 |
| Chen X et al. | Modular pathways for editing non-cognate amino acids by human cytoplasmic leucyl-tRNA synthetase. | 2011 | Nucleic Acids Res. | pmid:20805241 |
| Ji QQ et al. | Self-protective responses to norvaline-induced stress in a leucyl-tRNA synthetase editing-deficient yeast strain. | 2017 | Nucleic Acids Res. | pmid:28575390 |
| Zhou XL et al. | Aminoacylation and translational quality control strategy employed by leucyl-tRNA synthetase from a human pathogen with genetic code ambiguity. | 2013 | Nucleic Acids Res. | pmid:23969415 |
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| Alvarez-Carreño C et al. | Norvaline and norleucine may have been more abundant protein components during early stages of cell evolution. | 2013 | Orig Life Evol Biosph | pmid:24013929 |
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