L-norvaline is a lipid of Fatty Acyls (FA) class. L-norvaline is associated with abnormalities such as Celiac Disease, Exanthema, Atherosclerosis, Plasmodium falciparum infection and Parasitemia. The involved functions are known as Anabolism, Saturated, Stimulus, Physiologic Organization and arginase activity. L-norvaline often locates in Extracellular, Protoplasm, soluble, viral nucleocapsid location and Cell Wall. The associated genes with L-norvaline are norvaline, Amino Acids, Basic, ARG1 gene, Escherichia coli Proteins and Operon. The related lipids are Lipopolysaccharides.
To understand associated biological information of L-norvaline, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
L-norvaline is suspected in Exanthema, Parasitemia, Celiac Disease, Atherosclerosis, Plasmodium falciparum infection and other diseases in descending order of the highest number of associated sentences.
| Disease | Cross reference | Weighted score | Related literature |
|---|
We collected disease MeSH terms mapped to the references associated with L-norvaline
| MeSH term | MeSH ID | Detail |
|---|---|---|
| Adenocarcinoma | D000230 | 166 associated lipids |
| Diabetes Mellitus, Experimental | D003921 | 85 associated lipids |
| Kidney Diseases | D007674 | 29 associated lipids |
| Liver Neoplasms, Experimental | D008114 | 46 associated lipids |
| Carcinoma, Hepatocellular | D006528 | 140 associated lipids |
| Celiac Disease | D002446 | 16 associated lipids |
| Metabolic Syndrome | D024821 | 44 associated lipids |
| Marek Disease | D008380 | 4 associated lipids |
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
| Location | Cross reference | Weighted score | Related literatures |
|---|
| Function | Cross reference | Weighted score | Related literatures |
|---|
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
| Gene | Cross reference | Weighted score | Related literatures |
|---|
There are no associated biomedical information in the current reference collection.
| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Kuznetsov NA et al. | Pre-steady-state kinetic and structural analysis of interaction of methionine γ-lyase from Citrobacter freundii with inhibitors. | 2015 | J. Biol. Chem. | pmid:25398880 |
| pmid:25542213 | ||||
| pmid:25695622 | ||||
| pmid:25794326 | ||||
| Veeravalli K and Laird MW | Toward an era of utilizing methionine overproducing hosts for recombinant protein production in Escherichia coli. | 2015 | Bioengineered | pmid:25801611 |
| pmid:25841644 | ||||
| pmid:26146397 | ||||
| Dalal S and Klemba M | Amino acid efflux by asexual blood-stage Plasmodium falciparum and its utility in interrogating the kinetics of hemoglobin endocytosis and catabolism in vivo. | 2015 | Mol. Biochem. Parasitol. | pmid:26215764 |
| Ye Q et al. | Degenerate connective polypeptide 1 (CP1) domain from human mitochondrial leucyl-tRNA synthetase. | 2015 | J. Biol. Chem. | pmid:26272616 |
| pmid:26671005 | ||||
| pmid:26857261 | ||||
| Isozaki K et al. | Synthesis and Applications of (ONO Pincer)Ruthenium-Complex-Bound Norvalines. | 2016 | Chem Asian J | pmid:26879368 |
| Palekar AG et al. | Failure of sodium benzoate to alleviate plasma and liver ammonia in rats. | 1989 | Biochem. Med. Metab. Biol. | pmid:2713151 |
| Arslan M et al. | DL-2-amino-5-phosphonopentanoic acid, a specific N-methyl-D-aspartic acid receptor antagonist, suppresses pulsatile LH release in the rat. | 1988 | Neuroendocrinology | pmid:2840595 |
| Ji QQ et al. | Self-protective responses to norvaline-induced stress in a leucyl-tRNA synthetase editing-deficient yeast strain. | 2017 | Nucleic Acids Res. | pmid:28575390 |
| Wallace CJ and Corthésy BE | Protein engineering of cytochrome c by semisynthesis: substitutions at glutamic acid 66. | 1986 Oct-Nov | Protein Eng. | pmid:2907133 |
| Xiong XF and Anderson PM | Purification and properties of ornithine carbamoyl transferase from liver of Squalus acanthias. | 1989 | Arch. Biochem. Biophys. | pmid:2930186 |
| Juillerat MA and Taniuchi H | A study on the role of evolutionarily invariant leucine 32 of cytochrome c. | 1986 | J. Biol. Chem. | pmid:3005260 |
| Hagberg RC et al. | Comparison of cyclosporin A and G with and without azathioprine regarding immunosuppressive efficacy, toxicity, and pharmacokinetics in Lewis rats. | 1988 Sep-Oct | J Heart Transplant | pmid:3058906 |
| Kuo LC et al. | Site-directed mutagenesis of Escherichia coli ornithine transcarbamoylase: role of arginine-57 in substrate binding and catalysis. | 1988 | Biochemistry | pmid:3072022 |