Dl-serine

Dl-serine is a lipid of Fatty Acyls (FA) class. Dl-serine is associated with abnormalities such as Spastic syndrome, Machado-Joseph Disease, Huntington Disease, Infection and Gram positive septicemia. The involved functions are known as Lipid Binding, Proteolysis, Protein Processing, Post-Translational, Cytokinesis and Phosphorylation. Dl-serine often locates in Anatomic Site, Membrane, Cytoplasmic Domain, Extracellular and Blood. The associated genes with Dl-serine are polyserine, lipovitellin, Polypeptides, CSNK2A1 wt Allele and Spider Proteins. The related experimental models are Mouse Model.

Cross Reference

Introduction

To understand associated biological information of Dl-serine, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Dl-serine?

Dl-serine is suspected in Huntington Disease, Infection, Spastic syndrome, Machado-Joseph Disease, Gram positive septicemia and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Dl-serine

MeSH term MeSH ID Detail
Kidney Neoplasms D007680 29 associated lipids
Body Weight D001835 333 associated lipids
Spinocerebellar Ataxias D020754 4 associated lipids
Total 3

PubChem Associated disorders and diseases

What pathways are associated with Dl-serine

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Dl-serine?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Dl-serine?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Dl-serine?

There are no associated biomedical information in the current reference collection.

What genes are associated with Dl-serine?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Dl-serine?

Mouse Model

Mouse Model are used in the study 'Polyalanine and polyserine frameshift products in Huntington's disease.' (Davies JE and Rubinsztein DC, 2006).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
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NCBI Entrez Crosslinks

All references with Dl-serine

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Authors Title Published Journal PubMed Link
Lorca RA et al. The unique N-terminal sequence of the BKCa channel α-subunit determines its modulation by β-subunits. 2017 PLoS ONE pmid:28750098
Bañez-Coronel M et al. RAN Translation in Huntington Disease. 2015 Neuron pmid:26590344
Zhao Z et al. Self-assembled micelles of amphiphilic poly(L-phenylalanine)-b-poly(L-serine) polypeptides for tumor-targeted delivery. 2014 Int J Nanomedicine pmid:25540585
Lu Y et al. Self-folded redox/acid dual-responsive nanocarriers for anticancer drug delivery. 2014 Chem. Commun. (Camb.) pmid:25331017
Tian X et al. A conserved extraordinarily long serine homopolymer in Dictyostelid amoebae. 2014 Heredity (Edinb) pmid:24084645
Liu Q et al. Amino acid-based zwitterionic poly(serine methacrylate) as an antifouling material. 2013 Biomacromolecules pmid:23228182
Szczawinska-Poplonyk A An overlapping syndrome of allergy and immune deficiency in children. 2012 J Allergy (Cairo) pmid:21918651
Olma A et al. A convenient route to optically pure α-alkyl-β-(sec-amino)alanines. 2012 Amino Acids pmid:21847610
Havukainen H et al. A vitellogenin polyserine cleavage site: highly disordered conformation protected from proteolysis by phosphorylation. 2012 J. Exp. Biol. pmid:22573762
Geng F et al. Multiple post-translational modifications regulate E-cadherin transport during apoptosis. 2012 J. Cell. Sci. pmid:22375065