MeSH term | MeSH ID | Detail |
---|---|---|
Spinocerebellar Ataxias | D020754 | 4 associated lipids |
Kidney Neoplasms | D007680 | 29 associated lipids |
Body Weight | D001835 | 333 associated lipids |
Dl-serine is a lipid of Fatty Acyls (FA) class. Dl-serine is associated with abnormalities such as Spastic syndrome, Machado-Joseph Disease, Huntington Disease, Infection and Gram positive septicemia. The involved functions are known as Lipid Binding, Proteolysis, Protein Processing, Post-Translational, Cytokinesis and Phosphorylation. Dl-serine often locates in Anatomic Site, Membrane, Cytoplasmic Domain, Extracellular and Blood. The associated genes with Dl-serine are polyserine, lipovitellin, Polypeptides, CSNK2A1 wt Allele and Spider Proteins. The related experimental models are Mouse Model.
To understand associated biological information of Dl-serine, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
Dl-serine is suspected in Huntington Disease, Infection, Spastic syndrome, Machado-Joseph Disease, Gram positive septicemia and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
---|
We collected disease MeSH terms mapped to the references associated with Dl-serine
MeSH term | MeSH ID | Detail |
---|---|---|
Spinocerebellar Ataxias | D020754 | 4 associated lipids |
Kidney Neoplasms | D007680 | 29 associated lipids |
Body Weight | D001835 | 333 associated lipids |
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
---|
Function | Cross reference | Weighted score | Related literatures |
---|
There are no associated biomedical information in the current reference collection.
Gene | Cross reference | Weighted score | Related literatures |
---|
Mouse Model are used in the study 'Polyalanine and polyserine frameshift products in Huntington's disease.' (Davies JE and Rubinsztein DC, 2006).
Model | Cross reference | Weighted score | Related literatures |
---|
Authors | Title | Published | Journal | PubMed Link |
---|---|---|---|---|
Mahmoud SA et al. | Production and chemical studies of protease from Bacillus subtilis (SH-6) Egyptian strain. | 1978 | Zentralbl Bakteriol Naturwiss | pmid:98932 |
Gonsalves KE et al. | Synthesis and surface characterization of functionalized polylactide copolymer microparticles. | 1998 | Biomaterials | pmid:9794526 |
Aoki Y et al. | Anti-proliferative effects of unmodified antisense oligodeoxynucleotides targeted against c-raf mRNA: use of poly (lysine/serine) copolymers or cationic lipopolyamines. | 1998 | Clin. Exp. Pharmacol. Physiol. | pmid:9750959 |
Bates PA and DeLuca NA | The polyserine tract of herpes simplex virus ICP4 is required for normal viral gene expression and growth in murine trigeminal ganglia. | 1998 | J. Virol. | pmid:9696805 |
Doruker P and Bahar I | Role of water on unfolding kinetics of helical peptides studied by molecular dynamics simulations. | 1997 | Biophys. J. | pmid:9168021 |
Evans JS et al. | Prediction of polyelectrolyte polypeptide structures using Monte Carlo conformational search methods with implicit solvation modeling. | 1995 | Protein Sci. | pmid:8535238 |
Joshi SV et al. | Gamma-irradiation studies with synthetic poly-L-serine in the megarad dose range. | 1980 | Cancer Biochem. Biophys. | pmid:7438027 |
Kovác L et al. | Membrane mutants: a yeast mutant with a lesion in phosphatidylserine biosynthesis. | 1980 | Eur. J. Biochem. | pmid:6780341 |
Hiasa Y et al. | DL-Serine: promoting activity on renal tumorigenesis by N-ethyl-N-hydroxyethylnitrosamine in rats. | 1984 | J. Natl. Cancer Inst. | pmid:6429402 |
Nakagawa M and Uchiyama M | Effect of organophosphate pesticides on lecithin-cholesterol acyltransferase in human plasma. | 1974 | Biochem. Pharmacol. | pmid:4847537 |
Janjić TJ and Milovanović GA | New kinetic method for determination of ultramicro quantities of organic substances. Determination of amino acids (glycine, DL-serine, DL-phenylalanine, DL-glutamic acid, and L-arginine). | 1973 | Anal. Chem. | pmid:4762355 |
Wells IC et al. | Experimental study of chronic ambulatory peritoneal dialysis. I. Inhibition of protein and amino acid losses by single amino acids. | 1985 | Clin Physiol Biochem | pmid:3995871 |
Scott TA and Hockney RC | Synthesis of vitamin B6 by a mutant of Escherichia coli K12 and the action of 4'-deoxypyridoxine. | 1979 | J. Gen. Microbiol. | pmid:374679 |
Weber AL | Stereoselective formation of a 2'(3')-aminoacyl ester of a nucleotide. | 1987 | J. Mol. Evol. | pmid:3114501 |
Lorca RA et al. | The unique N-terminal sequence of the BKCa channel α-subunit determines its modulation by β-subunits. | 2017 | PLoS ONE | pmid:28750098 |
pmid:28079384 | ||||
Bañez-Coronel M et al. | RAN Translation in Huntington Disease. | 2015 | Neuron | pmid:26590344 |
Zhao Z et al. | Self-assembled micelles of amphiphilic poly(L-phenylalanine)-b-poly(L-serine) polypeptides for tumor-targeted delivery. | 2014 | Int J Nanomedicine | pmid:25540585 |
Lu Y et al. | Self-folded redox/acid dual-responsive nanocarriers for anticancer drug delivery. | 2014 | Chem. Commun. (Camb.) | pmid:25331017 |
Tian X et al. | A conserved extraordinarily long serine homopolymer in Dictyostelid amoebae. | 2014 | Heredity (Edinb) | pmid:24084645 |
Liu Q et al. | Amino acid-based zwitterionic poly(serine methacrylate) as an antifouling material. | 2013 | Biomacromolecules | pmid:23228182 |
pmid:22961244 | ||||
Tang H et al. | Water-soluble poly(L-serine)s with elongated and charged side-chains: synthesis, conformations, and cell-penetrating properties. | 2012 | Biomacromolecules | pmid:22853191 |
pmid:22747426 | ||||
Watanabe M et al. | Haemodynamic changes in the superior mesenteric artery induced by acupuncture stimulation on the lower limbs. | 2012 | Evid Based Complement Alternat Med | pmid:22675391 |
Li JM and Jin J | CRL Ubiquitin Ligases and DNA Damage Response. | 2012 | Front Oncol | pmid:22655267 |
Brown EC and Brüne M | The role of prediction in social neuroscience. | 2012 | Front Hum Neurosci | pmid:22654749 |
pmid:22652304 | ||||
Rusconi ML and Carelli L | Long-term efficacy of prism adaptation on spatial neglect: preliminary results on different spatial components. | 2012 | ScientificWorldJournal | pmid:22629167 |
pmid:22610678 | ||||
Bandholtz S et al. | Molecular evolution of a peptide GPCR ligand driven by artificial neural networks. | 2012 | PLoS ONE | pmid:22606313 |
Hammouda A et al. | Maternal antibody transmission in relation to mother fluctuating asymmetry in a long-lived colonial seabird: the yellow-legged gull Larus michahellis. | 2012 | PLoS ONE | pmid:22590497 |
Havukainen H et al. | A vitellogenin polyserine cleavage site: highly disordered conformation protected from proteolysis by phosphorylation. | 2012 | J. Exp. Biol. | pmid:22573762 |
Nesta B et al. | FdeC, a novel broadly conserved Escherichia coli adhesin eliciting protection against urinary tract infections. | 2012 | MBio | pmid:22496310 |
Abstracts of the 6th cachexia conference, milan, Italy, december 8-10, 2011. | 2011 | J Cachexia Sarcopenia Muscle | pmid:22476871 | |
pmid:22448784 | ||||
Barrientos R et al. | Wire marking results in a small but significant reduction in avian mortality at power lines: a BACI designed study. | 2012 | PLoS ONE | pmid:22396776 |
Geng F et al. | Multiple post-translational modifications regulate E-cadherin transport during apoptosis. | 2012 | J. Cell. Sci. | pmid:22375065 |
pmid:22339283 | ||||
Tada Y et al. | A 90-day Feeding Toxicity Study of l-Serine in Male and Female Fischer 344 Rats. | 2010 | J Toxicol Pathol | pmid:22272010 |
Ehrlich D et al. | Effects of long-term moderate ethanol and cholesterol on cognition, cholinergic neurons, inflammation, and vascular impairment in rats. | 2012 | Neuroscience | pmid:22244974 |
Cabezón O et al. | Seropositivity and risk factors associated with Toxoplasma gondii infection in wild birds from Spain. | 2011 | PLoS ONE | pmid:22216311 |
Maguinness C et al. | The effect of combined sensory and semantic components on audio-visual speech perception in older adults. | 2011 | Front Aging Neurosci | pmid:22207848 |
Agostinis C et al. | MBL interferes with endovascular trophoblast invasion in pre-eclampsia. | 2012 | Clin. Dev. Immunol. | pmid:22203857 |
Kutyshenko VP et al. | Analyzing and mapping sweat metabolomics by high-resolution NMR spectroscopy. | 2011 | PLoS ONE | pmid:22194922 |
Holmes RS and Cox LA | Comparative Structures and Evolution of Vertebrate Carboxyl Ester Lipase (CEL) Genes and Proteins with a Major Role in Reverse Cholesterol Transport. | 2011 | Cholesterol | pmid:22162806 |
Ishigami Y and Klein RM | Repeated Measurement of the Components of Attention of Older Adults using the Two Versions of the Attention Network Test: Stability, Isolability, Robustness, and Reliability. | 2011 | Front Aging Neurosci | pmid:22110440 |
Valkov A et al. | The prognostic impact of Akt isoforms, PI3K and PTEN related to female steroid hormone receptors in soft tissue sarcomas. | 2011 | J Transl Med | pmid:22107784 |
Lobanov MY and Galzitskaya OV | Disordered patterns in clustered Protein Data Bank and in eukaryotic and bacterial proteomes. | 2011 | PLoS ONE | pmid:22073276 |
Sheikhha MH et al. | Investigating the association between polymorphism of follicle-stimulating hormone receptor gene and ovarian response in controlled ovarian hyperstimulation. | 2011 | J Hum Reprod Sci | pmid:22064672 |