MeSH term | MeSH ID | Detail |
---|---|---|
Body Weight | D001835 | 333 associated lipids |
Kidney Neoplasms | D007680 | 29 associated lipids |
Spinocerebellar Ataxias | D020754 | 4 associated lipids |
Dl-serine is a lipid of Fatty Acyls (FA) class. Dl-serine is associated with abnormalities such as Spastic syndrome, Machado-Joseph Disease, Huntington Disease, Infection and Gram positive septicemia. The involved functions are known as Lipid Binding, Proteolysis, Protein Processing, Post-Translational, Cytokinesis and Phosphorylation. Dl-serine often locates in Anatomic Site, Membrane, Cytoplasmic Domain, Extracellular and Blood. The associated genes with Dl-serine are polyserine, lipovitellin, Polypeptides, CSNK2A1 wt Allele and Spider Proteins. The related experimental models are Mouse Model.
To understand associated biological information of Dl-serine, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
Dl-serine is suspected in Huntington Disease, Infection, Spastic syndrome, Machado-Joseph Disease, Gram positive septicemia and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with Dl-serine
MeSH term | MeSH ID | Detail |
---|---|---|
Body Weight | D001835 | 333 associated lipids |
Kidney Neoplasms | D007680 | 29 associated lipids |
Spinocerebellar Ataxias | D020754 | 4 associated lipids |
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
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Function | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Gene | Cross reference | Weighted score | Related literatures |
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Mouse Model are used in the study 'Polyalanine and polyserine frameshift products in Huntington's disease.' (Davies JE and Rubinsztein DC, 2006).
Model | Cross reference | Weighted score | Related literatures |
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Authors | Title | Published | Journal | PubMed Link |
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Bogár F et al. | Density functional study of infinite polyserine chains. | 2005 | Phys Chem Chem Phys | pmid:16189618 |
Abstracts of the 2008 ISSOL Meeting. August 24-29, 2008. Florence, Italy. | 2009 | Orig Life Evol Biosph | pmid:19468860 | |
Esposito A et al. | First stereocontrolled synthesis of (S)-cleonin and related cyclopropyl-substituted amino acids. | 2001 | Org. Lett. | pmid:11594812 |
Ortega-Andreu M et al. | Blood loss control with two doses of tranexamic Acid in a multimodal protocol for total knee arthroplasty. | 2011 | Open Orthop J | pmid:21552468 |
Cameron D et al. | Lapatinib plus capecitabine in women with HER-2-positive advanced breast cancer: final survival analysis of a phase III randomized trial. | 2010 | Oncologist | pmid:20736298 |
Kimura T et al. | Effect of serine residue on the effectiveness of cationic polypeptide-based gene delivery. | 2000 | Nucleic Acids Symp. Ser. | pmid:12903387 |
Ehrlich D et al. | Effects of long-term moderate ethanol and cholesterol on cognition, cholinergic neurons, inflammation, and vascular impairment in rats. | 2012 | Neuroscience | pmid:22244974 |
Bañez-Coronel M et al. | RAN Translation in Huntington Disease. | 2015 | Neuron | pmid:26590344 |
Zhou H et al. | Effect of resveratrol on gliotransmitter levels and p38 activities in cultured astrocytes. | 2011 | Neurochem. Res. | pmid:20842424 |
Kedinger V et al. | Targeted expression of tumor necrosis factor-related apoptosis-inducing ligand TRAIL in skin protects mice against chemical carcinogenesis. | 2011 | Mol. Cancer | pmid:21463519 |
Almeida L et al. | Plasminogen interaction with Trypanosoma cruzi. | 2004 | Mem. Inst. Oswaldo Cruz | pmid:15057349 |
Mariani R et al. | Iron metabolism in thalassemia and sickle cell disease. | 2009 | Mediterr J Hematol Infect Dis | pmid:21415988 |
Nesta B et al. | FdeC, a novel broadly conserved Escherichia coli adhesin eliciting protection against urinary tract infections. | 2012 | MBio | pmid:22496310 |
Bates PA and DeLuca NA | The polyserine tract of herpes simplex virus ICP4 is required for normal viral gene expression and growth in murine trigeminal ganglia. | 1998 | J. Virol. | pmid:9696805 |
Hiasa Y et al. | DL-Serine: promoting activity on renal tumorigenesis by N-ethyl-N-hydroxyethylnitrosamine in rats. | 1984 | J. Natl. Cancer Inst. | pmid:6429402 |
Weber AL | Stereoselective formation of a 2'(3')-aminoacyl ester of a nucleotide. | 1987 | J. Mol. Evol. | pmid:3114501 |
Davies JE and Rubinsztein DC | Polyalanine and polyserine frameshift products in Huntington's disease. | 2006 | J. Med. Genet. | pmid:16801344 |
Scott TA and Hockney RC | Synthesis of vitamin B6 by a mutant of Escherichia coli K12 and the action of 4'-deoxypyridoxine. | 1979 | J. Gen. Microbiol. | pmid:374679 |
Havukainen H et al. | A vitellogenin polyserine cleavage site: highly disordered conformation protected from proteolysis by phosphorylation. | 2012 | J. Exp. Biol. | pmid:22573762 |
Geng F et al. | Multiple post-translational modifications regulate E-cadherin transport during apoptosis. | 2012 | J. Cell. Sci. | pmid:22375065 |