MeSH term | MeSH ID | Detail |
---|---|---|
Body Weight | D001835 | 333 associated lipids |
Kidney Neoplasms | D007680 | 29 associated lipids |
Spinocerebellar Ataxias | D020754 | 4 associated lipids |
Dl-serine is a lipid of Fatty Acyls (FA) class. Dl-serine is associated with abnormalities such as Spastic syndrome, Machado-Joseph Disease, Huntington Disease, Infection and Gram positive septicemia. The involved functions are known as Lipid Binding, Proteolysis, Protein Processing, Post-Translational, Cytokinesis and Phosphorylation. Dl-serine often locates in Anatomic Site, Membrane, Cytoplasmic Domain, Extracellular and Blood. The associated genes with Dl-serine are polyserine, lipovitellin, Polypeptides, CSNK2A1 wt Allele and Spider Proteins. The related experimental models are Mouse Model.
To understand associated biological information of Dl-serine, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
Dl-serine is suspected in Huntington Disease, Infection, Spastic syndrome, Machado-Joseph Disease, Gram positive septicemia and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with Dl-serine
MeSH term | MeSH ID | Detail |
---|---|---|
Body Weight | D001835 | 333 associated lipids |
Kidney Neoplasms | D007680 | 29 associated lipids |
Spinocerebellar Ataxias | D020754 | 4 associated lipids |
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
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Function | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Gene | Cross reference | Weighted score | Related literatures |
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Mouse Model are used in the study 'Polyalanine and polyserine frameshift products in Huntington's disease.' (Davies JE and Rubinsztein DC, 2006).
Model | Cross reference | Weighted score | Related literatures |
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Authors | Title | Published | Journal | PubMed Link |
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Zhao Z et al. | Self-assembled micelles of amphiphilic poly(L-phenylalanine)-b-poly(L-serine) polypeptides for tumor-targeted delivery. | 2014 | Int J Nanomedicine | pmid:25540585 |
Szczawinska-Poplonyk A | An overlapping syndrome of allergy and immune deficiency in children. | 2012 | J Allergy (Cairo) | pmid:21918651 |
Abstracts of the 6th cachexia conference, milan, Italy, december 8-10, 2011. | 2011 | J Cachexia Sarcopenia Muscle | pmid:22476871 | |
Sheikhha MH et al. | Investigating the association between polymorphism of follicle-stimulating hormone receptor gene and ovarian response in controlled ovarian hyperstimulation. | 2011 | J Hum Reprod Sci | pmid:22064672 |
Scherübl C et al. | Colocalization of endogenous TNF with a functional intracellular splice form of human TNF receptor type 2. | 2005 | J Inflamm (Lond) | pmid:15996269 |
Tada Y et al. | A 90-day Feeding Toxicity Study of l-Serine in Male and Female Fischer 344 Rats. | 2010 | J Toxicol Pathol | pmid:22272010 |
Valkov A et al. | The prognostic impact of Akt isoforms, PI3K and PTEN related to female steroid hormone receptors in soft tissue sarcomas. | 2011 | J Transl Med | pmid:22107784 |
RodrÃguez-González R et al. | Association between neuroserpin and molecular markers of brain damage in patients with acute ischemic stroke. | 2011 | J Transl Med | pmid:21569344 |
Rostelato-Ferreira S et al. | Heparin at low concentration acts as antivenom against Bothrops jararacussu venom and bothropstoxin-I neurotoxic and myotoxic actions. | 2010 | J Venom Res | pmid:21544183 |
Halo TL et al. | Selective recognition of protein tetraserine motifs with a cell-permeable, pro-fluorescent bis-boronic acid. | 2009 | J. Am. Chem. Soc. | pmid:19105691 |
Bauer H et al. | The dual role of zonula occludens (ZO) proteins. | 2010 | J. Biomed. Biotechnol. | pmid:20224657 |
Geng F et al. | Multiple post-translational modifications regulate E-cadherin transport during apoptosis. | 2012 | J. Cell. Sci. | pmid:22375065 |
Havukainen H et al. | A vitellogenin polyserine cleavage site: highly disordered conformation protected from proteolysis by phosphorylation. | 2012 | J. Exp. Biol. | pmid:22573762 |
Scott TA and Hockney RC | Synthesis of vitamin B6 by a mutant of Escherichia coli K12 and the action of 4'-deoxypyridoxine. | 1979 | J. Gen. Microbiol. | pmid:374679 |
Davies JE and Rubinsztein DC | Polyalanine and polyserine frameshift products in Huntington's disease. | 2006 | J. Med. Genet. | pmid:16801344 |
Weber AL | Stereoselective formation of a 2'(3')-aminoacyl ester of a nucleotide. | 1987 | J. Mol. Evol. | pmid:3114501 |
Hiasa Y et al. | DL-Serine: promoting activity on renal tumorigenesis by N-ethyl-N-hydroxyethylnitrosamine in rats. | 1984 | J. Natl. Cancer Inst. | pmid:6429402 |
Bates PA and DeLuca NA | The polyserine tract of herpes simplex virus ICP4 is required for normal viral gene expression and growth in murine trigeminal ganglia. | 1998 | J. Virol. | pmid:9696805 |
Nesta B et al. | FdeC, a novel broadly conserved Escherichia coli adhesin eliciting protection against urinary tract infections. | 2012 | MBio | pmid:22496310 |
Mariani R et al. | Iron metabolism in thalassemia and sickle cell disease. | 2009 | Mediterr J Hematol Infect Dis | pmid:21415988 |