MeSH term | MeSH ID | Detail |
---|---|---|
Body Weight | D001835 | 333 associated lipids |
Kidney Neoplasms | D007680 | 29 associated lipids |
Spinocerebellar Ataxias | D020754 | 4 associated lipids |
Dl-serine is a lipid of Fatty Acyls (FA) class. Dl-serine is associated with abnormalities such as Spastic syndrome, Machado-Joseph Disease, Huntington Disease, Infection and Gram positive septicemia. The involved functions are known as Lipid Binding, Proteolysis, Protein Processing, Post-Translational, Cytokinesis and Phosphorylation. Dl-serine often locates in Anatomic Site, Membrane, Cytoplasmic Domain, Extracellular and Blood. The associated genes with Dl-serine are polyserine, lipovitellin, Polypeptides, CSNK2A1 wt Allele and Spider Proteins. The related experimental models are Mouse Model.
To understand associated biological information of Dl-serine, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
Dl-serine is suspected in Huntington Disease, Infection, Spastic syndrome, Machado-Joseph Disease, Gram positive septicemia and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with Dl-serine
MeSH term | MeSH ID | Detail |
---|---|---|
Body Weight | D001835 | 333 associated lipids |
Kidney Neoplasms | D007680 | 29 associated lipids |
Spinocerebellar Ataxias | D020754 | 4 associated lipids |
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
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Function | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Gene | Cross reference | Weighted score | Related literatures |
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Mouse Model are used in the study 'Polyalanine and polyserine frameshift products in Huntington's disease.' (Davies JE and Rubinsztein DC, 2006).
Model | Cross reference | Weighted score | Related literatures |
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Authors | Title | Published | Journal | PubMed Link |
---|---|---|---|---|
Oliveira MJ et al. | Beta-casein-derived peptides, produced by bacteria, stimulate cancer cell invasion and motility. | 2003 | EMBO J. | pmid:14609961 |
Amar J et al. | Intestinal mucosal adherence and translocation of commensal bacteria at the early onset of type 2 diabetes: molecular mechanisms and probiotic treatment. | 2011 | EMBO Mol Med | pmid:21735552 |
Kehe K et al. | Sulfur mustard research--strategies for the development of improved medical therapy. | 2008 | Eplasty | pmid:18615149 |
Kovác L et al. | Membrane mutants: a yeast mutant with a lesion in phosphatidylserine biosynthesis. | 1980 | Eur. J. Biochem. | pmid:6780341 |
Watanabe M et al. | Haemodynamic changes in the superior mesenteric artery induced by acupuncture stimulation on the lower limbs. | 2012 | Evid Based Complement Alternat Med | pmid:22675391 |
Maguinness C et al. | The effect of combined sensory and semantic components on audio-visual speech perception in older adults. | 2011 | Front Aging Neurosci | pmid:22207848 |
Ishigami Y and Klein RM | Repeated Measurement of the Components of Attention of Older Adults using the Two Versions of the Attention Network Test: Stability, Isolability, Robustness, and Reliability. | 2011 | Front Aging Neurosci | pmid:22110440 |
Brown EC and Brüne M | The role of prediction in social neuroscience. | 2012 | Front Hum Neurosci | pmid:22654749 |
Jerse AE et al. | Estradiol-Treated Female Mice as Surrogate Hosts for Neisseria gonorrhoeae Genital Tract Infections. | 2011 | Front Microbiol | pmid:21747807 |
Zhu W et al. | Vaccines for gonorrhea: can we rise to the challenge? | 2011 | Front Microbiol | pmid:21687431 |
van Elk M et al. | Neural evidence for compromised motor imagery in right hemiparetic cerebral palsy. | 2010 | Front Neurol | pmid:21206766 |
Li JM and Jin J | CRL Ubiquitin Ligases and DNA Damage Response. | 2012 | Front Oncol | pmid:22655267 |
Mogensen J | Reorganization of the injured brain: implications for studies of the neural substrate of cognition. | 2011 | Front Psychol | pmid:21713186 |
Jacobs S et al. | Studying Multisensory Processing and Its Role in the Representation of Space through Pathological and Physiological Crossmodal Extinction. | 2011 | Front Psychol | pmid:21687458 |
Cuppini C et al. | Organization, maturation, and plasticity of multisensory integration: insights from computational modeling studies. | 2011 | Front Psychol | pmid:21687448 |
da Silva AC et al. | Spi2 gene polymorphism is not associated with recurrent airway obstruction and inflammatory airway disease in thoroughbred horses. | 2011 | Genet. Mol. Biol. | pmid:21931519 |
Tian X et al. | A conserved extraordinarily long serine homopolymer in Dictyostelid amoebae. | 2014 | Heredity (Edinb) | pmid:24084645 |
Célérier J et al. | Angiotensinogen and its cleaved derivatives inhibit angiogenesis. | 2002 | Hypertension | pmid:11847188 |
Prakash M et al. | Serum paraoxonase activity and protein thiols in chronic renal failure patients. | 2008 | Indian J Nephrol | pmid:20368914 |
Beyer K et al. | Molecular pathology of Lewy body diseases. | 2009 | Int J Mol Sci | pmid:19399218 |
Zhao Z et al. | Self-assembled micelles of amphiphilic poly(L-phenylalanine)-b-poly(L-serine) polypeptides for tumor-targeted delivery. | 2014 | Int J Nanomedicine | pmid:25540585 |
Szczawinska-Poplonyk A | An overlapping syndrome of allergy and immune deficiency in children. | 2012 | J Allergy (Cairo) | pmid:21918651 |
Abstracts of the 6th cachexia conference, milan, Italy, december 8-10, 2011. | 2011 | J Cachexia Sarcopenia Muscle | pmid:22476871 | |
Sheikhha MH et al. | Investigating the association between polymorphism of follicle-stimulating hormone receptor gene and ovarian response in controlled ovarian hyperstimulation. | 2011 | J Hum Reprod Sci | pmid:22064672 |
Scherübl C et al. | Colocalization of endogenous TNF with a functional intracellular splice form of human TNF receptor type 2. | 2005 | J Inflamm (Lond) | pmid:15996269 |
Tada Y et al. | A 90-day Feeding Toxicity Study of l-Serine in Male and Female Fischer 344 Rats. | 2010 | J Toxicol Pathol | pmid:22272010 |
Valkov A et al. | The prognostic impact of Akt isoforms, PI3K and PTEN related to female steroid hormone receptors in soft tissue sarcomas. | 2011 | J Transl Med | pmid:22107784 |
RodrÃguez-González R et al. | Association between neuroserpin and molecular markers of brain damage in patients with acute ischemic stroke. | 2011 | J Transl Med | pmid:21569344 |
Rostelato-Ferreira S et al. | Heparin at low concentration acts as antivenom against Bothrops jararacussu venom and bothropstoxin-I neurotoxic and myotoxic actions. | 2010 | J Venom Res | pmid:21544183 |
Halo TL et al. | Selective recognition of protein tetraserine motifs with a cell-permeable, pro-fluorescent bis-boronic acid. | 2009 | J. Am. Chem. Soc. | pmid:19105691 |
Bauer H et al. | The dual role of zonula occludens (ZO) proteins. | 2010 | J. Biomed. Biotechnol. | pmid:20224657 |
Geng F et al. | Multiple post-translational modifications regulate E-cadherin transport during apoptosis. | 2012 | J. Cell. Sci. | pmid:22375065 |
Havukainen H et al. | A vitellogenin polyserine cleavage site: highly disordered conformation protected from proteolysis by phosphorylation. | 2012 | J. Exp. Biol. | pmid:22573762 |
Scott TA and Hockney RC | Synthesis of vitamin B6 by a mutant of Escherichia coli K12 and the action of 4'-deoxypyridoxine. | 1979 | J. Gen. Microbiol. | pmid:374679 |
Davies JE and Rubinsztein DC | Polyalanine and polyserine frameshift products in Huntington's disease. | 2006 | J. Med. Genet. | pmid:16801344 |
Weber AL | Stereoselective formation of a 2'(3')-aminoacyl ester of a nucleotide. | 1987 | J. Mol. Evol. | pmid:3114501 |
Hiasa Y et al. | DL-Serine: promoting activity on renal tumorigenesis by N-ethyl-N-hydroxyethylnitrosamine in rats. | 1984 | J. Natl. Cancer Inst. | pmid:6429402 |
Bates PA and DeLuca NA | The polyserine tract of herpes simplex virus ICP4 is required for normal viral gene expression and growth in murine trigeminal ganglia. | 1998 | J. Virol. | pmid:9696805 |
Nesta B et al. | FdeC, a novel broadly conserved Escherichia coli adhesin eliciting protection against urinary tract infections. | 2012 | MBio | pmid:22496310 |
Mariani R et al. | Iron metabolism in thalassemia and sickle cell disease. | 2009 | Mediterr J Hematol Infect Dis | pmid:21415988 |
Almeida L et al. | Plasminogen interaction with Trypanosoma cruzi. | 2004 | Mem. Inst. Oswaldo Cruz | pmid:15057349 |
Kedinger V et al. | Targeted expression of tumor necrosis factor-related apoptosis-inducing ligand TRAIL in skin protects mice against chemical carcinogenesis. | 2011 | Mol. Cancer | pmid:21463519 |
Zhou H et al. | Effect of resveratrol on gliotransmitter levels and p38 activities in cultured astrocytes. | 2011 | Neurochem. Res. | pmid:20842424 |
Bañez-Coronel M et al. | RAN Translation in Huntington Disease. | 2015 | Neuron | pmid:26590344 |
Ehrlich D et al. | Effects of long-term moderate ethanol and cholesterol on cognition, cholinergic neurons, inflammation, and vascular impairment in rats. | 2012 | Neuroscience | pmid:22244974 |
Kimura T et al. | Effect of serine residue on the effectiveness of cationic polypeptide-based gene delivery. | 2000 | Nucleic Acids Symp. Ser. | pmid:12903387 |
Cameron D et al. | Lapatinib plus capecitabine in women with HER-2-positive advanced breast cancer: final survival analysis of a phase III randomized trial. | 2010 | Oncologist | pmid:20736298 |
Ortega-Andreu M et al. | Blood loss control with two doses of tranexamic Acid in a multimodal protocol for total knee arthroplasty. | 2011 | Open Orthop J | pmid:21552468 |
Esposito A et al. | First stereocontrolled synthesis of (S)-cleonin and related cyclopropyl-substituted amino acids. | 2001 | Org. Lett. | pmid:11594812 |
Abstracts of the 2008 ISSOL Meeting. August 24-29, 2008. Florence, Italy. | 2009 | Orig Life Evol Biosph | pmid:19468860 |