MeSH term | MeSH ID | Detail |
---|---|---|
Kidney Neoplasms | D007680 | 29 associated lipids |
Body Weight | D001835 | 333 associated lipids |
Spinocerebellar Ataxias | D020754 | 4 associated lipids |
Dl-serine is a lipid of Fatty Acyls (FA) class. Dl-serine is associated with abnormalities such as Spastic syndrome, Machado-Joseph Disease, Huntington Disease, Infection and Gram positive septicemia. The involved functions are known as Lipid Binding, Proteolysis, Protein Processing, Post-Translational, Cytokinesis and Phosphorylation. Dl-serine often locates in Anatomic Site, Membrane, Cytoplasmic Domain, Extracellular and Blood. The associated genes with Dl-serine are polyserine, lipovitellin, Polypeptides, CSNK2A1 wt Allele and Spider Proteins. The related experimental models are Mouse Model.
To understand associated biological information of Dl-serine, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
Dl-serine is suspected in Huntington Disease, Infection, Spastic syndrome, Machado-Joseph Disease, Gram positive septicemia and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with Dl-serine
MeSH term | MeSH ID | Detail |
---|---|---|
Kidney Neoplasms | D007680 | 29 associated lipids |
Body Weight | D001835 | 333 associated lipids |
Spinocerebellar Ataxias | D020754 | 4 associated lipids |
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
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Function | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Gene | Cross reference | Weighted score | Related literatures |
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Mouse Model are used in the study 'Polyalanine and polyserine frameshift products in Huntington's disease.' (Davies JE and Rubinsztein DC, 2006).
Model | Cross reference | Weighted score | Related literatures |
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Authors | Title | Published | Journal | PubMed Link |
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Cabezón O et al. | Seropositivity and risk factors associated with Toxoplasma gondii infection in wild birds from Spain. | 2011 | PLoS ONE | pmid:22216311 |
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Arthur JW and Reichardt JK | Modeling single nucleotide polymorphisms in the human AKR1C1 and AKR1C2 genes: implications for functional and genotyping analyses. | 2010 | PLoS ONE | pmid:21217827 |
Lobsiger CS et al. | Toxicity from different SOD1 mutants dysregulates the complement system and the neuronal regenerative response in ALS motor neurons. | 2007 | Proc. Natl. Acad. Sci. U.S.A. | pmid:17463094 |
Zu T et al. | Non-ATG-initiated translation directed by microsatellite expansions. | 2011 | Proc. Natl. Acad. Sci. U.S.A. | pmid:21173221 |
Howard MB et al. | Identification and analysis of polyserine linker domains in prokaryotic proteins with emphasis on the marine bacterium Microbulbifer degradans. | 2004 | Protein Sci. | pmid:15075401 |