| MeSH term | MeSH ID | Detail |
|---|---|---|
| Kidney Neoplasms | D007680 | 29 associated lipids |
| Body Weight | D001835 | 333 associated lipids |
| Spinocerebellar Ataxias | D020754 | 4 associated lipids |
Total
3
Dl-serine
Dl-serine is a lipid of Fatty Acyls (FA) class. Dl-serine is associated with abnormalities such as Spastic syndrome, Machado-Joseph Disease, Huntington Disease, Infection and Gram positive septicemia. The involved functions are known as Lipid Binding, Proteolysis, Protein Processing, Post-Translational, Cytokinesis and Phosphorylation. Dl-serine often locates in Anatomic Site, Membrane, Cytoplasmic Domain, Extracellular and Blood. The associated genes with Dl-serine are polyserine, lipovitellin, Polypeptides, CSNK2A1 wt Allele and Spider Proteins. The related experimental models are Mouse Model.
Cross Reference
Introduction
To understand associated biological information of Dl-serine, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with Dl-serine?
Dl-serine is suspected in Huntington Disease, Infection, Spastic syndrome, Machado-Joseph Disease, Gram positive septicemia and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with Dl-serine
PubChem Associated disorders and diseases
What pathways are associated with Dl-serine
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with Dl-serine?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
- Proc. Natl. Acad. Sci. U.S.A. (1)
- Am. J. Physiol. Heart Circ. Physiol. (1)
- Dev. Comp. Immunol. (1)
- Others (3)
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with Dl-serine?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with Dl-serine?
There are no associated biomedical information in the current reference collection.
What genes are associated with Dl-serine?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with Dl-serine?
Mouse Model
Mouse Model are used in the study 'Polyalanine and polyserine frameshift products in Huntington's disease.' (Davies JE and Rubinsztein DC, 2006).
Related references are published most in these journals:
| Model | Cross reference | Weighted score | Related literatures |
|---|
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NCBI Entrez Crosslinks
All references with Dl-serine
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Mahmoud SA et al. | Production and chemical studies of protease from Bacillus subtilis (SH-6) Egyptian strain. | 1978 | Zentralbl Bakteriol Naturwiss | pmid:98932 |
| Gonsalves KE et al. | Synthesis and surface characterization of functionalized polylactide copolymer microparticles. | 1998 | Biomaterials | pmid:9794526 |
| Aoki Y et al. | Anti-proliferative effects of unmodified antisense oligodeoxynucleotides targeted against c-raf mRNA: use of poly (lysine/serine) copolymers or cationic lipopolyamines. | 1998 | Clin. Exp. Pharmacol. Physiol. | pmid:9750959 |
| Bates PA and DeLuca NA | The polyserine tract of herpes simplex virus ICP4 is required for normal viral gene expression and growth in murine trigeminal ganglia. | 1998 | J. Virol. | pmid:9696805 |
| Doruker P and Bahar I | Role of water on unfolding kinetics of helical peptides studied by molecular dynamics simulations. | 1997 | Biophys. J. | pmid:9168021 |
| Evans JS et al. | Prediction of polyelectrolyte polypeptide structures using Monte Carlo conformational search methods with implicit solvation modeling. | 1995 | Protein Sci. | pmid:8535238 |
| Joshi SV et al. | Gamma-irradiation studies with synthetic poly-L-serine in the megarad dose range. | 1980 | Cancer Biochem. Biophys. | pmid:7438027 |
| Kovác L et al. | Membrane mutants: a yeast mutant with a lesion in phosphatidylserine biosynthesis. | 1980 | Eur. J. Biochem. | pmid:6780341 |
| Hiasa Y et al. | DL-Serine: promoting activity on renal tumorigenesis by N-ethyl-N-hydroxyethylnitrosamine in rats. | 1984 | J. Natl. Cancer Inst. | pmid:6429402 |
| Nakagawa M and Uchiyama M | Effect of organophosphate pesticides on lecithin-cholesterol acyltransferase in human plasma. | 1974 | Biochem. Pharmacol. | pmid:4847537 |
| Janjić TJ and Milovanović GA | New kinetic method for determination of ultramicro quantities of organic substances. Determination of amino acids (glycine, DL-serine, DL-phenylalanine, DL-glutamic acid, and L-arginine). | 1973 | Anal. Chem. | pmid:4762355 |
| Wells IC et al. | Experimental study of chronic ambulatory peritoneal dialysis. I. Inhibition of protein and amino acid losses by single amino acids. | 1985 | Clin Physiol Biochem | pmid:3995871 |
| Scott TA and Hockney RC | Synthesis of vitamin B6 by a mutant of Escherichia coli K12 and the action of 4'-deoxypyridoxine. | 1979 | J. Gen. Microbiol. | pmid:374679 |
| Weber AL | Stereoselective formation of a 2'(3')-aminoacyl ester of a nucleotide. | 1987 | J. Mol. Evol. | pmid:3114501 |
| Lorca RA et al. | The unique N-terminal sequence of the BKCa channel α-subunit determines its modulation by β-subunits. | 2017 | PLoS ONE | pmid:28750098 |
| pmid:28079384 | ||||
| Bañez-Coronel M et al. | RAN Translation in Huntington Disease. | 2015 | Neuron | pmid:26590344 |
| Zhao Z et al. | Self-assembled micelles of amphiphilic poly(L-phenylalanine)-b-poly(L-serine) polypeptides for tumor-targeted delivery. | 2014 | Int J Nanomedicine | pmid:25540585 |
| Lu Y et al. | Self-folded redox/acid dual-responsive nanocarriers for anticancer drug delivery. | 2014 | Chem. Commun. (Camb.) | pmid:25331017 |
| Tian X et al. | A conserved extraordinarily long serine homopolymer in Dictyostelid amoebae. | 2014 | Heredity (Edinb) | pmid:24084645 |