Dl-serine

Dl-serine is a lipid of Fatty Acyls (FA) class. Dl-serine is associated with abnormalities such as Spastic syndrome, Machado-Joseph Disease, Huntington Disease, Infection and Gram positive septicemia. The involved functions are known as Lipid Binding, Proteolysis, Protein Processing, Post-Translational, Cytokinesis and Phosphorylation. Dl-serine often locates in Anatomic Site, Membrane, Cytoplasmic Domain, Extracellular and Blood. The associated genes with Dl-serine are polyserine, lipovitellin, Polypeptides, CSNK2A1 wt Allele and Spider Proteins. The related experimental models are Mouse Model.

Cross Reference

Introduction

To understand associated biological information of Dl-serine, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Dl-serine?

Dl-serine is suspected in Huntington Disease, Infection, Spastic syndrome, Machado-Joseph Disease, Gram positive septicemia and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Dl-serine

MeSH term MeSH ID Detail
Kidney Neoplasms D007680 29 associated lipids
Body Weight D001835 333 associated lipids
Spinocerebellar Ataxias D020754 4 associated lipids
Total 3

PubChem Associated disorders and diseases

What pathways are associated with Dl-serine

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Dl-serine?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Dl-serine?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Dl-serine?

There are no associated biomedical information in the current reference collection.

What genes are associated with Dl-serine?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Dl-serine?

Mouse Model

Mouse Model are used in the study 'Polyalanine and polyserine frameshift products in Huntington's disease.' (Davies JE and Rubinsztein DC, 2006).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
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NCBI Entrez Crosslinks

All references with Dl-serine

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Authors Title Published Journal PubMed Link
pmid:
Schöttelndreier H et al. Beta1-integrins mediate Ca2+-signalling and T cell spreading via divergent pathways. 1999 Cell. Signal. pmid:10433522
Hasper A et al. Modification of the N-terminal polyserine cluster alters stability of the plasma membrane H(+)-ATPase from Saccharomyces cerevisiae. 1999 Biochim. Biophys. Acta pmid:10446304
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Esposito A et al. First stereocontrolled synthesis of (S)-cleonin and related cyclopropyl-substituted amino acids. 2001 Org. Lett. pmid:11594812
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Célérier J et al. Angiotensinogen and its cleaved derivatives inhibit angiogenesis. 2002 Hypertension pmid:11847188
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El-Awady RA et al. Radiosensitivity of human tumour cells is correlated with the induction but not with the repair of DNA double-strand breaks. 2003 Br. J. Cancer pmid:12888835
Kimura T et al. Effect of serine residue on the effectiveness of cationic polypeptide-based gene delivery. 2000 Nucleic Acids Symp. Ser. pmid:12903387
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Oliveira MJ et al. Beta-casein-derived peptides, produced by bacteria, stimulate cancer cell invasion and motility. 2003 EMBO J. pmid:14609961
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Almeida L et al. Plasminogen interaction with Trypanosoma cruzi. 2004 Mem. Inst. Oswaldo Cruz pmid:15057349
Howard MB et al. Identification and analysis of polyserine linker domains in prokaryotic proteins with emphasis on the marine bacterium Microbulbifer degradans. 2004 Protein Sci. pmid:15075401
Langenickel TH et al. Rat corin gene: molecular cloning and reduced expression in experimental heart failure. 2004 Am. J. Physiol. Heart Circ. Physiol. pmid:15155264
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Picking WD et al. Fluorescence characterization of the environment encountered by nascent polyalanine and polyserine as they exit Escherichia coli ribosomes during translation. 1992 Biochemistry pmid:1540593
pmid:15498505
Hujová J et al. Characterization of gana-1, a Caenorhabditis elegans gene encoding a single ortholog of vertebrate alpha-galactosidase and alpha-N-acetylgalactosaminidase. 2005 BMC Cell Biol. pmid:15676072
Funding M et al. Proteomic analysis of aqueous humour from patients with acute corneal rejection. 2005 Acta Ophthalmol Scand pmid:15715554
Schmitz KJ et al. High expression of focal adhesion kinase (p125FAK) in node-negative breast cancer is related to overexpression of HER-2/neu and activated Akt kinase but does not predict outcome. 2005 Breast Cancer Res. pmid:15743500
Rementeria A et al. Genes and molecules involved in Aspergillus fumigatus virulence. 2005 Rev Iberoam Micol pmid:15813678
pmid:15822973
Lefebvre-Lavoie J et al. Profiling of differentially expressed genes in wound margin biopsies of horses using suppression subtractive hybridization. 2005 Physiol. Genomics pmid:15870397
Scherübl C et al. Colocalization of endogenous TNF with a functional intracellular splice form of human TNF receptor type 2. 2005 J Inflamm (Lond) pmid:15996269
pmid:16005268
Biro JC Nucleic acid chaperons: a theory of an RNA-assisted protein folding. 2005 Theor Biol Med Model pmid:16137324
Bogár F et al. Density functional study of infinite polyserine chains. 2005 Phys Chem Chem Phys pmid:16189618
Rautengarten C et al. Inferring hypotheses on functional relationships of genes: Analysis of the Arabidopsis thaliana subtilase gene family. 2005 PLoS Comput. Biol. pmid:16193095
Gleeson DJ et al. Genetic covariance between indices of body condition and immunocompetence in a passerine bird. 2005 BMC Evol. Biol. pmid:16274488
Adam P et al. Studies of the intermediary metabolism in cultured cells of the insect Spodoptera frugiperda using 13C- or 15N-labelled tracers. 2005 BMC Biochem. pmid:16285881
pmid:16397121
Nagata H et al. Structural scaffold of 18-crown-6 tetracarboxylic Acid for optical resolution of chiral amino acid: x-ray crystal analyses of complexes of D- and L-isomers of serine and glutamic acid. 2006 Chem. Pharm. Bull. pmid:16595944
pmid:16679602
pmid:16718496
pmid:16787177
Li C Voltammetric determination of tyrosine based on an L-serine polymer film electrode. 2006 Colloids Surf B Biointerfaces pmid:16797945
Davies JE and Rubinsztein DC Polyalanine and polyserine frameshift products in Huntington's disease. 2006 J. Med. Genet. pmid:16801344
pmid:16853971
pmid:16872761
Mizejewski GJ et al. Anticancer versus antigrowth activities of three analogs of the growth-inhibitory peptide: relevance to physicochemical properties. 2006 Jul-Aug Anticancer Res. pmid:16886636
pmid:17156977