Dl-serine

Dl-serine is a lipid of Fatty Acyls (FA) class. Dl-serine is associated with abnormalities such as Spastic syndrome, Machado-Joseph Disease, Huntington Disease, Infection and Gram positive septicemia. The involved functions are known as Lipid Binding, Proteolysis, Protein Processing, Post-Translational, Cytokinesis and Phosphorylation. Dl-serine often locates in Anatomic Site, Membrane, Cytoplasmic Domain, Extracellular and Blood. The associated genes with Dl-serine are polyserine, lipovitellin, Polypeptides, CSNK2A1 wt Allele and Spider Proteins. The related experimental models are Mouse Model.

Cross Reference

Introduction

To understand associated biological information of Dl-serine, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Dl-serine?

Dl-serine is suspected in Huntington Disease, Infection, Spastic syndrome, Machado-Joseph Disease, Gram positive septicemia and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
Loading... please refresh the page if content is not showing up.

Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Dl-serine

MeSH term MeSH ID Detail
Kidney Neoplasms D007680 29 associated lipids
Body Weight D001835 333 associated lipids
Spinocerebellar Ataxias D020754 4 associated lipids
Total 3

PubChem Associated disorders and diseases

What pathways are associated with Dl-serine

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Dl-serine?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
Loading... please refresh the page if content is not showing up.

What functions are associated with Dl-serine?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Dl-serine?

There are no associated biomedical information in the current reference collection.

What genes are associated with Dl-serine?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Dl-serine?

Mouse Model

Mouse Model are used in the study 'Polyalanine and polyserine frameshift products in Huntington's disease.' (Davies JE and Rubinsztein DC, 2006).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
Loading... please refresh the page if content is not showing up.

NCBI Entrez Crosslinks

All references with Dl-serine

Download all related citations
Per page 10 20 50 100 | Total 191
Authors Title Published Journal PubMed Link
Mahmoud SA et al. Production and chemical studies of protease from Bacillus subtilis (SH-6) Egyptian strain. 1978 Zentralbl Bakteriol Naturwiss pmid:98932
Gonsalves KE et al. Synthesis and surface characterization of functionalized polylactide copolymer microparticles. 1998 Biomaterials pmid:9794526
Aoki Y et al. Anti-proliferative effects of unmodified antisense oligodeoxynucleotides targeted against c-raf mRNA: use of poly (lysine/serine) copolymers or cationic lipopolyamines. 1998 Clin. Exp. Pharmacol. Physiol. pmid:9750959
Bates PA and DeLuca NA The polyserine tract of herpes simplex virus ICP4 is required for normal viral gene expression and growth in murine trigeminal ganglia. 1998 J. Virol. pmid:9696805
Doruker P and Bahar I Role of water on unfolding kinetics of helical peptides studied by molecular dynamics simulations. 1997 Biophys. J. pmid:9168021
Evans JS et al. Prediction of polyelectrolyte polypeptide structures using Monte Carlo conformational search methods with implicit solvation modeling. 1995 Protein Sci. pmid:8535238
Joshi SV et al. Gamma-irradiation studies with synthetic poly-L-serine in the megarad dose range. 1980 Cancer Biochem. Biophys. pmid:7438027
Kovác L et al. Membrane mutants: a yeast mutant with a lesion in phosphatidylserine biosynthesis. 1980 Eur. J. Biochem. pmid:6780341
Hiasa Y et al. DL-Serine: promoting activity on renal tumorigenesis by N-ethyl-N-hydroxyethylnitrosamine in rats. 1984 J. Natl. Cancer Inst. pmid:6429402
Nakagawa M and Uchiyama M Effect of organophosphate pesticides on lecithin-cholesterol acyltransferase in human plasma. 1974 Biochem. Pharmacol. pmid:4847537
Janjić TJ and Milovanović GA New kinetic method for determination of ultramicro quantities of organic substances. Determination of amino acids (glycine, DL-serine, DL-phenylalanine, DL-glutamic acid, and L-arginine). 1973 Anal. Chem. pmid:4762355
Wells IC et al. Experimental study of chronic ambulatory peritoneal dialysis. I. Inhibition of protein and amino acid losses by single amino acids. 1985 Clin Physiol Biochem pmid:3995871
Scott TA and Hockney RC Synthesis of vitamin B6 by a mutant of Escherichia coli K12 and the action of 4'-deoxypyridoxine. 1979 J. Gen. Microbiol. pmid:374679
Weber AL Stereoselective formation of a 2'(3')-aminoacyl ester of a nucleotide. 1987 J. Mol. Evol. pmid:3114501
Lorca RA et al. The unique N-terminal sequence of the BKCa channel α-subunit determines its modulation by β-subunits. 2017 PLoS ONE pmid:28750098
pmid:28079384
Bañez-Coronel M et al. RAN Translation in Huntington Disease. 2015 Neuron pmid:26590344
Zhao Z et al. Self-assembled micelles of amphiphilic poly(L-phenylalanine)-b-poly(L-serine) polypeptides for tumor-targeted delivery. 2014 Int J Nanomedicine pmid:25540585
Lu Y et al. Self-folded redox/acid dual-responsive nanocarriers for anticancer drug delivery. 2014 Chem. Commun. (Camb.) pmid:25331017
Tian X et al. A conserved extraordinarily long serine homopolymer in Dictyostelid amoebae. 2014 Heredity (Edinb) pmid:24084645
Liu Q et al. Amino acid-based zwitterionic poly(serine methacrylate) as an antifouling material. 2013 Biomacromolecules pmid:23228182
pmid:22961244
Tang H et al. Water-soluble poly(L-serine)s with elongated and charged side-chains: synthesis, conformations, and cell-penetrating properties. 2012 Biomacromolecules pmid:22853191
pmid:22747426
Watanabe M et al. Haemodynamic changes in the superior mesenteric artery induced by acupuncture stimulation on the lower limbs. 2012 Evid Based Complement Alternat Med pmid:22675391
Li JM and Jin J CRL Ubiquitin Ligases and DNA Damage Response. 2012 Front Oncol pmid:22655267
Brown EC and Brüne M The role of prediction in social neuroscience. 2012 Front Hum Neurosci pmid:22654749
pmid:22652304
Rusconi ML and Carelli L Long-term efficacy of prism adaptation on spatial neglect: preliminary results on different spatial components. 2012 ScientificWorldJournal pmid:22629167
pmid:22610678
Bandholtz S et al. Molecular evolution of a peptide GPCR ligand driven by artificial neural networks. 2012 PLoS ONE pmid:22606313
Hammouda A et al. Maternal antibody transmission in relation to mother fluctuating asymmetry in a long-lived colonial seabird: the yellow-legged gull Larus michahellis. 2012 PLoS ONE pmid:22590497
Havukainen H et al. A vitellogenin polyserine cleavage site: highly disordered conformation protected from proteolysis by phosphorylation. 2012 J. Exp. Biol. pmid:22573762
Nesta B et al. FdeC, a novel broadly conserved Escherichia coli adhesin eliciting protection against urinary tract infections. 2012 MBio pmid:22496310
Abstracts of the 6th cachexia conference, milan, Italy, december 8-10, 2011. 2011 J Cachexia Sarcopenia Muscle pmid:22476871
pmid:22448784
Barrientos R et al. Wire marking results in a small but significant reduction in avian mortality at power lines: a BACI designed study. 2012 PLoS ONE pmid:22396776
Geng F et al. Multiple post-translational modifications regulate E-cadherin transport during apoptosis. 2012 J. Cell. Sci. pmid:22375065
pmid:22339283
Tada Y et al. A 90-day Feeding Toxicity Study of l-Serine in Male and Female Fischer 344 Rats. 2010 J Toxicol Pathol pmid:22272010
Ehrlich D et al. Effects of long-term moderate ethanol and cholesterol on cognition, cholinergic neurons, inflammation, and vascular impairment in rats. 2012 Neuroscience pmid:22244974
Cabezón O et al. Seropositivity and risk factors associated with Toxoplasma gondii infection in wild birds from Spain. 2011 PLoS ONE pmid:22216311
Maguinness C et al. The effect of combined sensory and semantic components on audio-visual speech perception in older adults. 2011 Front Aging Neurosci pmid:22207848
Agostinis C et al. MBL interferes with endovascular trophoblast invasion in pre-eclampsia. 2012 Clin. Dev. Immunol. pmid:22203857
Kutyshenko VP et al. Analyzing and mapping sweat metabolomics by high-resolution NMR spectroscopy. 2011 PLoS ONE pmid:22194922
Holmes RS and Cox LA Comparative Structures and Evolution of Vertebrate Carboxyl Ester Lipase (CEL) Genes and Proteins with a Major Role in Reverse Cholesterol Transport. 2011 Cholesterol pmid:22162806
Ishigami Y and Klein RM Repeated Measurement of the Components of Attention of Older Adults using the Two Versions of the Attention Network Test: Stability, Isolability, Robustness, and Reliability. 2011 Front Aging Neurosci pmid:22110440
Valkov A et al. The prognostic impact of Akt isoforms, PI3K and PTEN related to female steroid hormone receptors in soft tissue sarcomas. 2011 J Transl Med pmid:22107784
Lobanov MY and Galzitskaya OV Disordered patterns in clustered Protein Data Bank and in eukaryotic and bacterial proteomes. 2011 PLoS ONE pmid:22073276
Sheikhha MH et al. Investigating the association between polymorphism of follicle-stimulating hormone receptor gene and ovarian response in controlled ovarian hyperstimulation. 2011 J Hum Reprod Sci pmid:22064672