MeSH term | MeSH ID | Detail |
---|---|---|
Kidney Neoplasms | D007680 | 29 associated lipids |
Body Weight | D001835 | 333 associated lipids |
Spinocerebellar Ataxias | D020754 | 4 associated lipids |
Dl-serine is a lipid of Fatty Acyls (FA) class. Dl-serine is associated with abnormalities such as Spastic syndrome, Machado-Joseph Disease, Huntington Disease, Infection and Gram positive septicemia. The involved functions are known as Lipid Binding, Proteolysis, Protein Processing, Post-Translational, Cytokinesis and Phosphorylation. Dl-serine often locates in Anatomic Site, Membrane, Cytoplasmic Domain, Extracellular and Blood. The associated genes with Dl-serine are polyserine, lipovitellin, Polypeptides, CSNK2A1 wt Allele and Spider Proteins. The related experimental models are Mouse Model.
To understand associated biological information of Dl-serine, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
Dl-serine is suspected in Huntington Disease, Infection, Spastic syndrome, Machado-Joseph Disease, Gram positive septicemia and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with Dl-serine
MeSH term | MeSH ID | Detail |
---|---|---|
Kidney Neoplasms | D007680 | 29 associated lipids |
Body Weight | D001835 | 333 associated lipids |
Spinocerebellar Ataxias | D020754 | 4 associated lipids |
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
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Function | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Gene | Cross reference | Weighted score | Related literatures |
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Mouse Model are used in the study 'Polyalanine and polyserine frameshift products in Huntington's disease.' (Davies JE and Rubinsztein DC, 2006).
Model | Cross reference | Weighted score | Related literatures |
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Authors | Title | Published | Journal | PubMed Link |
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Perera R et al. | Molecular basis for the inability of an oxygen atom donor ligand to replace the natural sulfur donor heme axial ligand in cytochrome P450 catalysis. Spectroscopic characterization of the Cys436Ser CYP2B4 mutant. | 2011 | Arch. Biochem. Biophys. | pmid:21147058 |
Nakagawa M and Uchiyama M | Effect of organophosphate pesticides on lecithin-cholesterol acyltransferase in human plasma. | 1974 | Biochem. Pharmacol. | pmid:4847537 |
Picking WD et al. | Fluorescence characterization of the environment encountered by nascent polyalanine and polyserine as they exit Escherichia coli ribosomes during translation. | 1992 | Biochemistry | pmid:1540593 |
Hasper A et al. | Modification of the N-terminal polyserine cluster alters stability of the plasma membrane H(+)-ATPase from Saccharomyces cerevisiae. | 1999 | Biochim. Biophys. Acta | pmid:10446304 |
Picking W et al. | The use of synthetic tRNAs as probes for examining nascent peptides on Escherichia coli ribosomes. | 1991 Jul-Aug | Biochimie | pmid:1742354 |
Bauer DC et al. | Sorting the nuclear proteome. | 2011 | Bioinformatics | pmid:21685104 |
Tang H et al. | Water-soluble poly(L-serine)s with elongated and charged side-chains: synthesis, conformations, and cell-penetrating properties. | 2012 | Biomacromolecules | pmid:22853191 |
Liu Q et al. | Amino acid-based zwitterionic poly(serine methacrylate) as an antifouling material. | 2013 | Biomacromolecules | pmid:23228182 |
Gonsalves KE et al. | Synthesis and surface characterization of functionalized polylactide copolymer microparticles. | 1998 | Biomaterials | pmid:9794526 |
Epand RF et al. | Amphipathic helical cationic antimicrobial peptides promote rapid formation of crystalline states in the presence of phosphatidylglycerol: lipid clustering in anionic membranes. | 2010 | Biophys. J. | pmid:20513400 |