Dl-leucine

Dl-leucine is a lipid of Fatty Acyls (FA) class.

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There are no associated biomedical information in the current reference collection.

Current reference collection contains 544 references associated with Dl-leucine in LipidPedia. Due to lack of full text of references or no associated biomedical terms are recognized in our current text-mining method, we cannot extract any biomedical terms related to diseases, pathways, locations, functions, genes, lipids, and animal models from the associated reference collection.

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Here are additional resources we collected from PubChem and MeSH for Dl-leucine

Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Dl-leucine

MeSH term MeSH ID Detail
Nerve Degeneration D009410 53 associated lipids
Myoclonic Epilepsies, Progressive D020191 3 associated lipids
Communicable Diseases, Emerging D021821 3 associated lipids
Influenza in Birds D005585 1 associated lipids
Total 4

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Bañez-Coronel M et al. RAN Translation in Huntington Disease. 2015 Neuron pmid:26590344
Zhang S et al. Design and synthesis of nonionic copolypeptide hydrogels with reversible thermoresponsive and tunable physical properties. 2015 Biomacromolecules pmid:25748800
Chen P et al. pH-Responsive chimaeric pepsomes based on asymmetric poly(ethylene glycol)-b-poly(l-leucine)-b-poly(l-glutamic acid) triblock copolymer for efficient loading and active intracellular delivery of doxorubicin hydrochloride. 2015 Biomacromolecules pmid:25759951
Han SS et al. Dual-pH Sensitive Charge-Reversal Polypeptide Micelles for Tumor-Triggered Targeting Uptake and Nuclear Drug Delivery. 2015 Small pmid:25626995
Ding J et al. Chirality-mediated polypeptide micelles for regulated drug delivery. 2015 Acta Biomater pmid:25278445
Swathi A et al. Homology modeling and structural comparison of leucine rich repeats of Toll like receptors 1-10 of ruminants. 2013 J Mol Model pmid:23812948
Nakano M et al. Study of the aggregation mechanism of polyglutamine peptides using replica exchange molecular dynamics simulations. 2013 J Mol Model pmid:23288093
Choe UJ et al. Endocytosis and intracellular trafficking properties of transferrin-conjugated block copolypeptide vesicles. 2013 Biomacromolecules pmid:23581747
Suzuki Y et al. Increased aggregation of polyleucine compared with that of polyglutamine in dentatorubral-pallidoluysian atrophy protein. 2013 Neurosci. Lett. pmid:23933208
Miranda RA et al. Synthesis and characterization of poly-L-leucine initialized and immobilized by rehydrated hydrotalcite: understanding stability and the nature of interaction. 2013 Phys Chem Chem Phys pmid:23942769
Drummond ML et al. The importance of secondary structure in determining CO2-protein binding patterns. 2012 J Mol Model pmid:22038461
van Eyk CL et al. Comparative toxicity of polyglutamine, polyalanine and polyleucine tracts in Drosophila models of expanded repeat disease. 2012 Hum. Mol. Genet. pmid:22021427
Deng J et al. Self-assembled cationic micelles based on PEG-PLL-PLLeu hybrid polypeptides as highly effective gene vectors. 2012 Biomacromolecules pmid:23013102
Gu PF et al. Polymeric micelles based on poly(ethylene glycol) block poly(racemic amino acids) hybrid polypeptides: conformation-facilitated drug-loading behavior and potential application as effective anticancer drug carriers. 2012 Int J Nanomedicine pmid:22275827
Poreba M et al. Fingerprinting the substrate specificity of M1 and M17 aminopeptidases of human malaria, Plasmodium falciparum. 2012 PLoS ONE pmid:22359643
Dutta P and Dey J Drug solubilization by amino acid based polymeric nanoparticles: Characterization and biocompatibility studies. 2011 Int J Pharm pmid:22001838
Schow EV et al. Arginine in membranes: the connection between molecular dynamics simulations and translocon-mediated insertion experiments. 2011 J. Membr. Biol. pmid:21127848
Sun VZ et al. Intracellular fates of cell-penetrating block copolypeptide vesicles. 2011 Biomacromolecules pmid:21128599
Wang R et al. Preparation and aggregation behavior of mannose-terminated poly(ethylene glycol)-b-poly(L-leucine) in water. 2011 Colloids Surf B Biointerfaces pmid:21144714
Gumbart J et al. Free-energy cost for translocon-assisted insertion of membrane proteins. 2011 Proc. Natl. Acad. Sci. U.S.A. pmid:21317362
Juhász A et al. Role of conserved non-coding regulatory elements in LMW glutenin gene expression. 2011 PLoS ONE pmid:22242127
Wang X et al. Polypeptide grafted hyaluronan: synthesis and characterization. 2010 Biomacromolecules pmid:20690642
Crouzier T et al. Polysaccharide-blend multilayers containing hyaluronan and heparin as a delivery system for rhBMP-2. 2010 Small pmid:20155753
Frost SH et al. In vitro evaluation of avidin antibody pretargeting using 211At-labeled and biotinylated poly-L-lysine as effector molecule. 2010 Cancer pmid:20127953
Dimitrova P and Bart HJ Non-ionic surfactant modified ligand exchange chromatography using copper (II) complex of N,N-dimethyl-L-phenylalanine as the chiral additive for enantioselective amino acids separation. 2010 Anal. Chim. Acta pmid:20172105
Jaud S et al. Insertion of short transmembrane helices by the Sec61 translocon. 2009 Proc. Natl. Acad. Sci. U.S.A. pmid:19581593
Lakkaraju SK and Hwang W Critical buckling length versus persistence length: what governs biofilament conformation? 2009 Phys. Rev. Lett. pmid:19392240
Abstracts of the 2008 ISSOL Meeting. August 24-29, 2008. Florence, Italy. 2009 Orig Life Evol Biosph pmid:19468860
Labonté P and Seidah NG Emerging viruses: risk of pandemic. 2008 Expert Rev Anti Infect Ther pmid:18847397
Kruhlak NL et al. Development of a phospholipidosis database and predictive quantitative structure-activity relationship (QSAR) models. 2008 Toxicol. Mech. Methods pmid:20020916
Lee J and Im W Role of hydrogen bonding and helix-lipid interactions in transmembrane helix association. 2008 J. Am. Chem. Soc. pmid:18422318
Akagawa K et al. Organocatalytic asymmetric transfer hydrogenation in aqueous media using resin-supported peptide having a polyleucine tether. 2008 Org. Lett. pmid:18407642
MacCallum JL et al. Hydrophobic association of alpha-helices, steric dewetting, and enthalpic barriers to protein folding. 2007 Proc. Natl. Acad. Sci. U.S.A. pmid:17404236
Dorairaj S and Allen TW On the thermodynamic stability of a charged arginine side chain in a transmembrane helix. 2007 Proc. Natl. Acad. Sci. U.S.A. pmid:17360368
Singh SK et al. Antidepressant binding site in a bacterial homologue of neurotransmitter transporters. 2007 Nature pmid:17687333
Holowka EP et al. Polyarginine segments in block copolypeptides drive both vesicular assembly and intracellular delivery. 2007 Nat Mater pmid:17143266
Filippou PS et al. Effect of polyamines and synthetic polyamine-analogues on the expression of antizyme (AtoC) and its regulatory genes. 2007 BMC Biochem. pmid:17224065
Lamazière A et al. [Transduction peptides: structural-functional analyses in model membranes]. 2006 J. Soc. Biol. pmid:17417137
Afara MR et al. Rational design of peptide inhibitors of the sarcoplasmic reticulum calcium pump. 2006 Biochemistry pmid:16834336
Mack M et al. 3-Methylglutaconyl-CoA hydratase from Acinetobacter sp. 2006 Arch. Microbiol. pmid:16482430
Orzáez M et al. Influence of hydrophobic matching on association of model transmembrane fragments containing a minimised glycophorin A dimerisation motif. 2005 FEBS Lett. pmid:15757653
Higuchi M et al. pH-induced reversible conformational and morphological regulation of polyleucine grafted polyallylamine assembly in solution. 2005 Langmuir pmid:16285826
Holowka EP et al. Charged polypeptide vesicles with controllable diameter. 2005 J. Am. Chem. Soc. pmid:16131225
Oma Y and Ishiura S [Cytotoxic effects of homopolyamino acids]. 2004 Tanpakushitsu Kakusan Koso pmid:15168547
Kelly DR and Roberts SM The mechanism of polyleucine catalysed asymmetric epoxidation. 2004 Chem. Commun. (Camb.) pmid:15367954
Kelly DR et al. Chiral amplification by polypeptides and its relevance to prebiotic catalysis. 2004 Chem. Commun. (Camb.) pmid:15367955
Ash WL et al. Computer modeling of polyleucine-based coiled coil dimers in a realistic membrane environment: insight into helix-helix interactions in membrane proteins. 2004 Biochemistry pmid:15248762
Caputo GA and London E Position and ionization state of Asp in the core of membrane-inserted alpha helices control both the equilibrium between transmembrane and nontransmembrane helix topography and transmembrane helix positioning. 2004 Biochemistry pmid:15236588
Carrea G et al. Kinetics of chalcone oxidation by peroxide anion catalysed by poly-l-leucine. 2004 Chem. Commun. (Camb.) pmid:15179490
Liu F et al. Effect of variations in the structure of a polyleucine-based alpha-helical transmembrane peptide on its interaction with phosphatidylethanolamine Bilayers. 2004 Biophys. J. pmid:15454444
Okamura TA et al. Right-handed helical structure of expanded oligo(L-leucine) containing [Ru(terpyridine)2]2+ moieties. 2004 J. Am. Chem. Soc. pmid:15584725
Liu F et al. Effect of variations in the structure of a polyleucine-based alpha-helical transmembrane peptide on its interaction with phosphatidylglycerol bilayers. 2004 Biochemistry pmid:15035638
Wang JP et al. Heptaaquatetra-mu3-hydroxy-hexa-mu2-L-leucine-(L-leucine)tetraytterbium(III) tetrachlorozinc(II) trichlorohydroxyzinc(II) tetrachloride octahydrate. 2004 Acta Crystallogr C pmid:15004369
Lazaridis T Effective energy function for proteins in lipid membranes. 2003 Proteins pmid:12833542
Collet O and Chipot C Non-arrhenius behavior in the unfolding of a short, hydrophobic alpha-helix. Complementarity of molecular dynamics and lattice model simulations. 2003 J. Am. Chem. Soc. pmid:12785798
Lew S et al. The effect of interactions involving ionizable residues flanking membrane-inserted hydrophobic helices upon helix-helix interaction. 2003 Biochemistry pmid:12962508
Dean KE et al. A green fluorescent chemosensor for amino acids provides a versatile high-throughput screening (HTS) assay for proteases. 2003 Bioorg. Med. Chem. Lett. pmid:12729634
Hessa T et al. Stop-transfer efficiency of marginally hydrophobic segments depends on the length of the carboxy-terminal tail. 2003 EMBO Rep. pmid:12612608
Friesema EC et al. Identification of monocarboxylate transporter 8 as a specific thyroid hormone transporter. 2003 J. Biol. Chem. pmid:12871948
Nowak AP et al. Unusual salt stability in highly charged diblock co-polypeptide hydrogels. 2003 J. Am. Chem. Soc. pmid:14664616
Lim VS et al. Insulin is protein-anabolic in chronic renal failure patients. 2003 J. Am. Soc. Nephrol. pmid:12937306
Kim DK et al. The human T-type amino acid transporter-1: characterization, gene organization, and chromosomal location. 2002 Genomics pmid:11827462
Swift-Scanlan T et al. Genetic analysis of the (CTG)n NOTCH4 polymorphism in 65 multiplex bipolar pedigrees. 2002 Psychiatr. Genet. pmid:11901359
Pratt LR and Pohorille A Hydrophobic effects and modeling of biophysical aqueous solution interfaces. 2002 Chem. Rev. pmid:12175264
Liu F et al. Effect of variations in the structure of a polyleucine-based alpha-helical transmembrane peptide on its interaction with phosphatidylcholine bilayers. 2002 Biochemistry pmid:12119034
Dorsman JC et al. Strong aggregation and increased toxicity of polyleucine over polyglutamine stretches in mammalian cells. 2002 Hum. Mol. Genet. pmid:12045202
Otsubo E and Takei T Effects of the human pulmonary surfactant protein-C (SP-C), SP-CL16(6-28) on surface activities of surfactants with various phospholipids. 2002 Biol. Pharm. Bull. pmid:12392083
Yan Z et al. Viscosity behavior of some alpha-amino acids and their groups in water-sodium acetate mixtures. 2002 Biophys. Chem. pmid:12408936
Thibodeaux SJ et al. Enantiomeric separations using poly(L-valine) and poly(L-leucine) surfactants. Investigation of steric factors near the chiral center. 2002 J Chromatogr A pmid:12214692
Hosia W et al. Hydrogen/deuterium exchange and aggregation of a polyvaline and a polyleucine alpha-helix investigated by matrix-assisted laser desorption ionization mass spectrometry. 2002 Mol. Cell Proteomics pmid:12376574
Zhou FX et al. Polar residues drive association of polyleucine transmembrane helices. 2001 Proc. Natl. Acad. Sci. U.S.A. pmid:11226225
Liu F et al. A differential scanning calorimetric and 31P NMR spectroscopic study of the effect of transmembrane alpha-helical peptides on the lamellar-reversed hexagonal phase transition of phosphatidylethanolamine model membranes. 2001 Biochemistry pmid:11170393
Dhanda A et al. PaaSiCats: novel polyamino acid catalysts. 2000 Chirality pmid:10824145
Lew S et al. The effects of polar and/or ionizable residues in the core and flanking regions of hydrophobic helices on transmembrane conformation and oligomerization. 2000 Biochemistry pmid:10933779
Chin CN and von Heijne G Charge pair interactions in a model transmembrane helix in the ER membrane. 2000 J. Mol. Biol. pmid:11021965
Kim HJ et al. Possibility of wound dressing using poly(L-leucine)/poly(ethylene glycol)/poly(L-leucine) triblock copolymer. 2000 Biomaterials pmid:10632395
Bonner WA The radiolysis and radioracemization of poly-L-leucines. 1999 Radiat. Res. pmid:10381845
Monné M et al. Turns in transmembrane helices: determination of the minimal length of a "helical hairpin" and derivation of a fine-grained turn propensity scale. 1999 J. Mol. Biol. pmid:10543969
Leser GP et al. The signal for clathrin-mediated endocytosis of the paramyxovirus SV5 HN protein resides at the transmembrane domain-ectodomain boundary region. 1999 Virology pmid:10489343
Braun P and von Heijne G The aromatic residues Trp and Phe have different effects on the positioning of a transmembrane helix in the microsomal membrane. 1999 Biochemistry pmid:10423258
Porter MJ et al. Polyamino acids as catalysts in asymmetric synthesis. 1999 Bioorg. Med. Chem. pmid:10579519
Efremov RG et al. A solvent model for simulations of peptides in bilayers. I. Membrane-promoting alpha-helix formation. 1999 Biophys. J. pmid:10233062
Monné M et al. Positively and negatively charged residues have different effects on the position in the membrane of a model transmembrane helix. 1998 J. Mol. Biol. pmid:9837735
Chipot C and Pohorille A Folding and translocation of the undecamer of poly-L-leucine across the water-hexane interface. A molecular dynamics study. 1998 J. Am. Chem. Soc. pmid:11542762
Lew S and London E Simple procedure for reversed-phase high-performance liquid chromatographic purification of long hydrophobic peptides that form transmembrane helices. 1997 Anal. Biochem. pmid:9300091
Hatsuzawa K et al. The hydrophobic region of signal peptides is a determinant for SRP recognition and protein translocation across the ER membrane. 1997 J. Biochem. pmid:9089400
Takei T et al. Characterization of poly-leucine substituted analogues of the human surfactant protein SP-C. 1996 Biol. Pharm. Bull. pmid:8996637
Whitley P et al. A 12-residue-long polyleucine tail is sufficient to anchor synaptobrevin to the endoplasmic reticulum membrane. 1996 J. Biol. Chem. pmid:8631791
Oliver AE and Deamer DW Alpha-helical hydrophobic polypeptides form proton-selective channels in lipid bilayers. 1994 Biophys. J. pmid:7520289
Lemmon MA et al. A dimerization motif for transmembrane alpha-helices. 1994 Nat. Struct. Biol. pmid:7656033
Vergères G and Waskell L Expression of cytochrome b5 in yeast and characterization of mutants of the membrane-anchoring domain. 1992 J. Biol. Chem. pmid:1618763
Nakajima Y et al. Greatly improved activity of staphylococcal ribosomes in polyadenylate directed polylysine synthesis: as an assay system for investigating their sensitivity to macrolide antibiotics. 1990 J. Pharmacobio-dyn. pmid:2121953
Hirayama C et al. Chromatographic resolution of dipeptide enantiomers and diastereomers on chiral stationary phases from poly(L-leucine) or poly(L-phenylalanine). 1988 J. Chromatogr. pmid:3235592
Hashimura T et al. Soft agar colony formation of bladder cells during carcinogenesis induced by N-butyl-N-(4-hydroxybutyl)nitrosamine and application to detection of bladder cancer promoters. 1987 Jpn. J. Cancer Res. pmid:3112059
Kakhniashvili DG et al. The excess GTP hydrolyzed during mistranslation is expended at the stage of EF-Tu-promoted binding of non-cognate aminoacyl-tRNA. 1986 FEBS Lett. pmid:3510907
Smailov SK and Gavrilova LP Effect of streptomycin on the stoichiometry of GTP hydrolysis in a poly(U)-dependent cell-free translation system. 1985 FEBS Lett. pmid:3902505
Usher DA and Needels MC On the stereoselective aminoacylation of RNA. 1984 Adv Space Res pmid:11537770
J Greenhow E and Viñas P A comparison of cationic polymerization and esterification for end-point detection in the catalytic thermometric titration of organic bases. 1984 Talanta pmid:18963660
Go M and Scheraga HA Molecular theory of the helix-coil transition in polyamino acids. V. Explanation of the different conformational behavior of valine, isoleucine, and leucine in aqueous solution. 1984 Biopolymers pmid:6498288
Gavrilova LP et al. Stoichiometry of GTP hydrolysis in a poly(U)-dependent cell-free translation system. Determination of GTP/peptide bond ratios during codon-specific elongation and misreading. 1984 FEBS Lett. pmid:6391958