2,4-diamino-butyric acid

2,4-diamino-butyric acid is a lipid of Fatty Acyls (FA) class.

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There are no associated biomedical information in the current reference collection.

Current reference collection contains 719 references associated with 2,4-diamino-butyric acid in LipidPedia. Due to lack of full text of references or no associated biomedical terms are recognized in our current text-mining method, we cannot extract any biomedical terms related to diseases, pathways, locations, functions, genes, lipids, and animal models from the associated reference collection.

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Here are additional resources we collected from PubChem and MeSH for 2,4-diamino-butyric acid

Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with 2,4-diamino-butyric acid

MeSH term MeSH ID Detail
Carcinoma, Hepatocellular D006528 140 associated lipids
Seizures D012640 87 associated lipids
Leukemia, Experimental D007942 42 associated lipids
Catalepsy D002375 30 associated lipids
Total 4

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All references with 2,4-diamino-butyric acid

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Authors Title Published Journal PubMed Link
Li A et al. New Typical Vector of Neurotoxin β-N-Methylamino-l-Alanine (BMAA) in the Marine Benthic Ecosystem. 2016 Mar Drugs pmid:27827914
Ngo JT et al. Click-EM for imaging metabolically tagged nonprotein biomolecules. 2016 Nat. Chem. Biol. pmid:27110681
Widderich N et al. Biochemistry and Crystal Structure of Ectoine Synthase: A Metal-Containing Member of the Cupin Superfamily. 2016 PLoS ONE pmid:26986827
Clark LC and Hodgkin J Leucobacter musarum subsp. musarum sp. nov., subsp. nov., Leucobacter musarum subsp. japonicus subsp. nov., and Leucobacter celer subsp. astrifaciens subsp. nov., three nematopathogenic bacteria isolated from Caenorhabditis, with an emended description of Leucobacter celer. 2015 Int. J. Syst. Evol. Microbiol. pmid:26275616
He YZ et al. High production of ectoine from aspartate and glycerol by use of whole-cell biocatalysis in recombinant Escherichia coli. 2015 Microb. Cell Fact. pmid:25886618
Al-Sammak MA et al. Co-occurrence of the cyanotoxins BMAA, DABA and anatoxin-a in Nebraska reservoirs, fish, and aquatic plants. 2014 Toxins (Basel) pmid:24476710
Kim SJ et al. Rudaibacter terrae gen. nov., sp. nov., isolated from greenhouse soil. 2013 Int. J. Syst. Evol. Microbiol. pmid:23728372
Jin L et al. Amnibacterium soli sp. nov., an actinobacterium isolated from grass soil. 2013 Int. J. Syst. Evol. Microbiol. pmid:23990652
Al-Sammak MA et al. Methods for simultaneous detection of the cyanotoxins BMAA, DABA, and anatoxin-a in environmental samples. 2013 Toxicon pmid:24140919
Li A et al. Elucidation of matrix effects and performance of solid-phase extraction for LC-MS/MS analysis of β-N-methylamino-L-alanine (BMAA) and 2,4-diaminobutyric acid (DAB) neurotoxins in cyanobacteria. 2012 Analyst pmid:22249403
Hoernke M et al. Binding of cationic pentapeptides with modified side chain lengths to negatively charged lipid membranes: Complex interplay of electrostatic and hydrophobic interactions. 2012 Biochim. Biophys. Acta pmid:22433675
Weon HY et al. Leucobacter denitrificans sp. nov., isolated from cow dung. 2012 J. Microbiol. pmid:22367952
Zhao H et al. In silico insights into the symbiotic nitrogen fixation in Sinorhizobium meliloti via metabolic reconstruction. 2012 PLoS ONE pmid:22319621
Srinivasan S et al. Pseudoclavibacter caeni sp. nov., isolated from sludge of a sewage disposal plant. 2012 Int. J. Syst. Evol. Microbiol. pmid:21571937
Gumpena R et al. Discovery of α,β- and α,γ-diamino acid scaffolds for the inhibition of M1 family aminopeptidases. 2011 ChemMedChem pmid:22025387
Beasley FC et al. Mutation of L-2,3-diaminopropionic acid synthase genes blocks staphyloferrin B synthesis in Staphylococcus aureus. 2011 BMC Microbiol. pmid:21906287
Shaheen M et al. Paenibacillus polymyxa PKB1 produces variants of polymyxin B-type antibiotics. 2011 Chem. Biol. pmid:22195566
Ates O et al. Genome-scale reconstruction of metabolic network for a halophilic extremophile, Chromohalobacter salexigens DSM 3043. 2011 BMC Syst Biol pmid:21251315
Bienfang PK et al. Prominent human health impacts from several marine microbes: history, ecology, and public health implications. 2011 Int J Microbiol pmid:20976073
Yun JH et al. Leucobacter salsicius sp. nov., from a salt-fermented food. 2011 Int. J. Syst. Evol. Microbiol. pmid:20363927
Kim HJ and Lee SS Leucobacter kyeonggiensis sp. nov., a new species isolated from dye waste water. 2011 J. Microbiol. pmid:22203572
Bajerski F et al. Cryobacterium arcticum sp. nov., a psychrotolerant bacterium from an Arctic soil. 2011 Int. J. Syst. Evol. Microbiol. pmid:20817836
Kim SJ and Lee SS Amnibacterium kyonggiense gen. nov., sp. nov., a new member of the family Microbacteriaceae. 2011 Int. J. Syst. Evol. Microbiol. pmid:20173001
Krüger T et al. LC-MS/MS determination of the isomeric neurotoxins BMAA (beta-N-methylamino-L-alanine) and DAB (2,4-diaminobutyric acid) in cyanobacteria and seeds of Cycas revoluta and Lathyrus latifolius. 2010 Feb-Mar Toxicon pmid:19825383
Martin E et al. Leucobacter aerolatus sp. nov., from the air of a duck barn. 2010 Int. J. Syst. Evol. Microbiol. pmid:20081017
Banack SA et al. The cyanobacteria derived toxin Beta-N-methylamino-L-alanine and amyotrophic lateral sclerosis. 2010 Toxins (Basel) pmid:22069578
Oland LA et al. Localization of a GABA transporter to glial cells in the developing and adult olfactory pathway of the moth Manduca sexta. 2010 J. Comp. Neurol. pmid:20058309
Banack SA et al. Distinguishing the cyanobacterial neurotoxin beta-N-methylamino-L-alanine (BMAA) from its structural isomer 2,4-diaminobutyric acid (2,4-DAB). 2010 Toxicon pmid:20561540
Li Q et al. Diastereo- and enantioselective synthesis of alpha,gamma-diaminobutyric acid derivatives via Cu-catalyzed asymmetric Michael reaction. 2010 Org. Lett. pmid:20143857
Prigol M et al. m-Trifluoromethyl-diphenyl diselenide attenuates pentylenetetrazole-induced seizures in mice by inhibiting GABA uptake in cerebral cortex slices. 2009 Nov-Dec Pharmacol Rep pmid:20081248
Gupta S et al. Colistin and polymyxin B: a re-emergence. 2009 Apr-Jun Indian J Crit Care Med pmid:19881183
Kanazawa K et al. Contribution of each amino acid residue in polymyxin B(3) to antimicrobial and lipopolysaccharide binding activity. 2009 Chem. Pharm. Bull. pmid:19252313
Lee J et al. An alternative polyamine biosynthetic pathway is widespread in bacteria and essential for biofilm formation in Vibrio cholerae. 2009 J. Biol. Chem. pmid:19196710
Berti AD and Thomas MG Analysis of achromobactin biosynthesis by Pseudomonas syringae pv. syringae B728a. 2009 J. Bacteriol. pmid:19482931
Craighead D et al. Presence of the neurotoxic amino acids beta-N-methylamino-L-alanine (BMAA) and 2,4-diamino-butyric acid (DAB) in shallow springs from the Gobi Desert. 2009 Amyotroph Lateral Scler pmid:19929740
Cox PA et al. Cyanobacteria and BMAA exposure from desert dust: a possible link to sporadic ALS among Gulf War veterans. 2009 Amyotroph Lateral Scler pmid:19929742
An SY et al. Leifsonia lichenia sp. nov., isolated from lichen in Japan. 2009 J. Gen. Appl. Microbiol. pmid:19940379
Chou CJ et al. Growth arrest of BCR-ABL positive cells with a sequence-specific polyamide-chlorambucil conjugate. 2008 PLoS ONE pmid:18974832
Vargas C et al. Unravelling the adaptation responses to osmotic and temperature stress in Chromohalobacter salexigens, a bacterium with broad salinity tolerance. 2008 Saline Syst. pmid:18793408
Bestvater T et al. Heterologous ectoine production in Escherichia coli: by-passing the metabolic bottle-neck. 2008 Saline Syst. pmid:18759971
Wolthers KR et al. Mechanism of radical-based catalysis in the reaction catalyzed by adenosylcobalamin-dependent ornithine 4,5-aminomutase. 2008 J. Biol. Chem. pmid:18948256
Behrendt U et al. Leucobacter tardus sp. nov., isolated from the phyllosphere of Solanum tuberosum L. 2008 Int. J. Syst. Evol. Microbiol. pmid:18984695
Reddy GS et al. Leifsonia pindariensis sp. nov., isolated from the Pindari glacier of the Indian Himalayas, and emended description of the genus Leifsonia. 2008 Int. J. Syst. Evol. Microbiol. pmid:18768634
Tominaga M et al. Antitumor effects of the MIG and IP-10 genes transferred with poly [D,L-2,4-diaminobutyric acid] on murine neuroblastoma. 2007 Cancer Gene Ther. pmid:17514193
Okimura K et al. Semi-synthesis of polymyxin B (2-10) and colistin (2-10) analogs employing the Trichloroethoxycarbonyl (Troc) group for side chain protection of alpha,gamma-diaminobutyric acid residues. 2007 Chem. Pharm. Bull. pmid:18057747
Bredehöft JH et al. Chiroptical properties of diamino carboxylic acids. 2007 Chirality pmid:17508400
Qiu F et al. Leifsonia ginsengi sp. nov., isolated from ginseng root. 2007 Int. J. Syst. Evol. Microbiol. pmid:17267987
Muir RE and Tan MW Leucobacter chromiireducens subsp. solipictus subsp. nov., a pigmented bacterium isolated from the nematode Caenorhabditis elegans, and emended description of L. chromiireducens. 2007 Int. J. Syst. Evol. Microbiol. pmid:18048723
Farkas ME et al. Alpha-diaminobutyric acid-linked hairpin polyamides. 2007 Bioorg. Med. Chem. pmid:17869122
Tsai SM et al. Unanticipated differences between alpha- and gamma-diaminobutyric acid-linked hairpin polyamide-alkylator conjugates. 2007 Nucleic Acids Res. pmid:17170006
Müller C et al. Sequencing and analysis of the biosynthetic gene cluster of the lipopeptide antibiotic Friulimicin in Actinoplanes friuliensis. 2007 Antimicrob. Agents Chemother. pmid:17220414
Lin YC and Yokota A Plantibacter auratus sp. nov., in the family Microbacteriaceae. 2006 Int. J. Syst. Evol. Microbiol. pmid:17012557
Ge L and Seah SY Heterologous expression, purification, and characterization of an l-ornithine N(5)-hydroxylase involved in pyoverdine siderophore biosynthesis in Pseudomonas aeruginosa. 2006 J. Bacteriol. pmid:17015659
Roviello GN et al. Synthesis, characterization and hybridization studies of new nucleo-gamma-peptides based on diaminobutyric acid. 2006 J. Pept. Sci. pmid:17131297
Bergenheim AT et al. Metabolic manipulation of glioblastoma in vivo by retrograde microdialysis of L-2, 4 diaminobutyric acid (DAB). 2006 J. Neurooncol. pmid:16773220
Roberts MF Organic compatible solutes of halotolerant and halophilic microorganisms. 2005 Saline Syst. pmid:16176595
Reshetnikov AS et al. Cloning, purification, and characterization of diaminobutyrate acetyltransferase from the halotolerant methanotroph Methylomicrobium alcaliphilum 20Z. 2005 Biochemistry Mosc. pmid:16212543
Wang Q and Lawrence DS Phosphorylation-driven protein-protein interactions: a protein kinase sensing system. 2005 J. Am. Chem. Soc. pmid:15913351
Micklefield J Nature's protection racket. 2005 Chem. Biol. pmid:15975504
Li Y et al. Biosynthesis of the unique amino acid side chain of butirosin: possible protective-group chemistry in an acyl carrier protein-mediated pathway. 2005 Chem. Biol. pmid:15975512
Vandenende CS et al. Functional characterization of an aminotransferase required for pyoverdine siderophore biosynthesis in Pseudomonas aeruginosa PAO1. 2004 J. Bacteriol. pmid:15317763
Farrera-Sinfreu J et al. A new class of foldamers based on cis-gamma-amino-L-proline. 2004 J. Am. Chem. Soc. pmid:15137770
Iwashita Y et al. Effective transfer of interleukin-12 gene to solid tumors using a novel gene delivery system, poly [D,L-2,4-diaminobutyric acid]. 2004 Cancer Gene Ther. pmid:14671674
Chen HP et al. Coexpression, purification and characterization of the E and S subunits of coenzyme B(12) and B(6) dependent Clostridium sticklandii D-ornithine aminomutase in Escherichia coli. 2004 Eur. J. Biochem. pmid:15511235
Leal SM et al. GABAergic modulation of motor-driven behaviors in juvenile Drosophila and evidence for a nonbehavioral role for GABA transport. 2004 J. Neurobiol. pmid:15389689
Blind PJ et al. Unique antitumour effects of L-2,4 diaminobutyric acid on cultured hepatoma cells. 2003 Mar-Apr Anticancer Res. pmid:12820378
Pflughoeft KJ et al. Role of ectoine in Vibrio cholerae osmoadaptation. 2003 Appl. Environ. Microbiol. pmid:14532045
Reddy GS et al. Leifsonia rubra sp. nov. and Leifsonia aurea sp. nov., psychrophiles from a pond in Antarctica. 2003 Int. J. Syst. Evol. Microbiol. pmid:12892114
Li WJ et al. Agromyces aurantiacus sp. nov., isolated from a Chinese primeval forest. 2003 Int. J. Syst. Evol. Microbiol. pmid:12656188
Linets'ka MV et al. [Effect of synaptosomal cytosolic [3H]GABA pool depletion on secretory ability of alpha-latrotoxin]. 2002 May-Jun Ukr Biokhim Zh (1999) pmid:12916239
Storchak LG et al. Does extracellular calcium determine what pool of GABA is the target for alpha-latrotoxin? 2002 Neurochem. Int. pmid:11821145
Weiss MA et al. Non-standard insulin design: structure-activity relationships at the periphery of the insulin receptor. 2002 J. Mol. Biol. pmid:11779231
Sitte HH et al. Bi-directional transport of GABA in human embryonic kidney (HEK-293) cells stably expressing the rat GABA transporter GAT-1. 2002 Br. J. Pharmacol. pmid:11786484
Harada K et al. Abnormal elution behavior of ornitine derivatized with 1-fluoro-2,4-dinitrophenyl-5-leucinamide in advanced Marfey's method. 2001 J Chromatogr A pmid:11471802
Huang H et al. Synthesis and evaluation of dipeptide amides containing N omega-nitroarginine and D-2,4-diaminobutyric acids as inhibitors of neuronal nitric oxide synthase. 2001 J. Enzym. Inhib. pmid:11697043
Stolze K et al. Novel spermine-amino acid conjugates and basic tripeptides enhance cleavage of the hairpin ribozyme at low magnesium ion concentration. 2001 Bioorg. Med. Chem. Lett. pmid:11714598
Evtushenko LI et al. Leifsonia poae gen. nov., sp. nov., isolated from nematode galls on Poa annua, and reclassification of 'Corynebacterium aquaticum' Leifson 1962 as Leifsonia aquatica (ex Leifson 1962) gen. nov., nom. rev., comb. nov. and Clavibacter xyli Davis et al. 1984 with two subspecies as Leifsonia xyli (Davis et al. 1984) gen. nov., comb. nov. 2000 Int. J. Syst. Evol. Microbiol. pmid:10826825
Schiller PW et al. Synthesis and in vitro opioid activity profiles of DALDA analogues. 2000 Eur J Med Chem pmid:11121615
Borthwick AD et al. Design and synthesis of pyrrolidine-5,5-trans-lactams (5-oxo-hexahydro-pyrrolo[3,2-b]pyrroles) as novel mechanism-based inhibitors of human cytomegalovirus protease. 1. The alpha-methyl-trans-lactam template. 2000 J. Med. Chem. pmid:11087570
Amabeoku GJ Gamma-aminobutyric acid and glutamic acid receptors may mediate theophylline-induced seizures in mice. 1999 Gen. Pharmacol. pmid:10211593
Ono H et al. Characterization of biosynthetic enzymes for ectoine as a compatible solute in a moderately halophilic eubacterium, Halomonas elongata. 1999 J. Bacteriol. pmid:9864317
Sasaki J et al. Taxonomic significance of 2,4-diaminobutyric acid isomers in the cell wall peptidoglycan of actinomycetes and reclassification of Clavibacter toxicus as Rathayibacter toxicus comb. nov. 1998 Int. J. Syst. Bacteriol. pmid:9731278
Murugaiah KD and Hemmings HC Effects of intravenous general anesthetics on [3H]GABA release from rat cortical synaptosomes. 1998 Anesthesiology pmid:9778010
Seeley MR and Faustman EM Evaluation of P19 cells for studying mechanisms of developmental toxicity: application to four direct-acting alkylating agents. 1998 Toxicology pmid:9699793
Antoni G et al. Synthesis of L-2,4-diamino[4-11C]butyric acid and its use in some in vitro and in vivo tumour models. 1997 Nucl. Med. Biol. pmid:9316090
Suzuki K et al. Cryobacterium psychrophilum gen. nov., sp. nov., nom. rev., comb. nov., an obligately psychrophilic actinomycete to accommodate "Curtobacterium psychrophilum" Inoue and Komagata 1976. 1997 Int. J. Syst. Bacteriol. pmid:9103638
Tung CH et al. Stabilization of DNA triple-helix formation by appended cationic peptides. 1996 Sep-Oct Bioconjug. Chem. pmid:8889011
Kuhn KS et al. Glutamine content of protein and peptide-based enteral products. 1996 Jul-Aug JPEN J Parenter Enteral Nutr pmid:8865112
Pow DV et al. Activity-dependent transport of GABA analogues into specific cell types demonstrated at high resolution using a novel immunocytochemical strategy. 1996 Neuroscience pmid:8809830
Suzuki K et al. Agromyces mediolanus sp. nov., nom. rev., comb. nov., a species for "Corynebacterium mediolanum" Mamoli 1939 and for some aniline-assimilating bacteria which contain 2,4-diaminobutyric acid in the cell wall peptidoglycan. 1996 Int. J. Syst. Bacteriol. pmid:8573525
Takeuchi M et al. Leucobacter komagatae gen. nov., sp. nov., a new aerobic gram-positive, nonsporulating rod with 2,4-diaminobutyric acid in the cell wall. 1996 Int. J. Syst. Bacteriol. pmid:8863425
Amabeoku G and Chikuni O GABAergic and dopaminergic systems may be involved in seizures induced by pyrimethamine in mice. 1994 Gen. Pharmacol. pmid:7875556
Amabeoku GJ and Chikuni O Cimetidine-induced seizures in mice. Antagonism by some GABAergic agents. 1993 Biochem. Pharmacol. pmid:8274150
Amabeoku G Involvement of GABAergic mechanisms in chloroquine-induced seizures in mice. 1992 Gen. Pharmacol. pmid:1639237
Ronquist G et al. Treatment of malignant glioma by a new therapeutic principle. 1992 Acta Neurochir (Wien) pmid:1561943
Amabeoku GJ and Chikuni O Effects of some GABAergic agents on quinine-induced seizures in mice. 1992 Experientia pmid:1322322
Christensen HN and Ronquist G Membrane transport properties of L-2,4-diaminobutyrate revisited. 1992 J. Membr. Biol. pmid:1404338
Krantis A and Clark D Localization of [3H]GABA-labelled nerve fibre networks in the rat intestinal mucosa. 1991 J. Auton. Nerv. Syst. pmid:1655859
Antoni G et al. Synthesis of 11C labeled basic amino acids. 1991 Acta Radiol Suppl pmid:1666803
Gonsalves SF et al. Anticonvulsant activity of intracerebroventricularly administered glial GABA uptake inhibitors and other GABAmimetics in chemical seizure models. 1989 Jul-Aug Epilepsy Res. pmid:2526732