2-amino-isobutyric acid

2-amino-isobutyric acid is a lipid of Fatty Acyls (FA) class.

Cross Reference

There are no associated biomedical information in the current reference collection.

Current reference collection contains 3622 references associated with 2-amino-isobutyric acid in LipidPedia. Due to lack of full text of references or no associated biomedical terms are recognized in our current text-mining method, we cannot extract any biomedical terms related to diseases, pathways, locations, functions, genes, lipids, and animal models from the associated reference collection.

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Here are additional resources we collected from PubChem and MeSH for 2-amino-isobutyric acid

Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with 2-amino-isobutyric acid

MeSH term MeSH ID Detail
Diabetes Mellitus D003920 90 associated lipids
Lung Neoplasms D008175 171 associated lipids
Colonic Neoplasms D003110 161 associated lipids
Body Weight D001835 333 associated lipids
Hypotension D007022 41 associated lipids
Prostatic Neoplasms D011471 126 associated lipids
Brain Neoplasms D001932 15 associated lipids
Hypothyroidism D007037 32 associated lipids
Leukemia, Erythroblastic, Acute D004915 41 associated lipids
Glioma D005910 112 associated lipids
Per page 10 20 50 | Total 47

PubChem Biomolecular Interactions and Pathways

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All references with 2-amino-isobutyric acid

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Per page 10 20 50 100 | Total 1224
Authors Title Published Journal PubMed Link
Jones JE et al. Length-Dependent Formation of Transmembrane Pores by 310-Helical α-Aminoisobutyric Acid Foldamers. 2016 J. Am. Chem. Soc. pmid:26699898
Tamaki H et al. Targeting Hormone-Related Pathways to Improve Grain Yield in Rice: A Chemical Approach. 2015 PLoS ONE pmid:26098557
Kosinová L et al. Insight into the structural and biological relevance of the T/R transition of the N-terminus of the B-chain in human insulin. 2014 Biochemistry pmid:24819248
Gessmann R et al. The peptide Z-Aib-Aib-Aib-L-Ala-OtBu. 2014 Acta Crystallogr C Struct Chem pmid:24705058
Gozes I et al. NAP alpha-aminoisobutyric acid (IsoNAP). 2014 J. Mol. Neurosci. pmid:24458740
Baird CH et al. L-Threonine induces heat shock protein expression and decreases apoptosis in heat-stressed intestinal epithelial cells. 2013 Nov-Dec Nutrition pmid:24103518
Hentrich M et al. YUCCA8 and YUCCA9 overexpression reveals a link between auxin signaling and lignification through the induction of ethylene biosynthesis. 2013 Plant Signal Behav pmid:24022251
Vogel KR et al. Non-physiological amino acid (NPAA) therapy targeting brain phenylalanine reduction: pilot studies in PAHENU2 mice. 2013 J. Inherit. Metab. Dis. pmid:22976763
Demizu Y et al. Development of stapled short helical peptides capable of inhibiting vitamin D receptor (VDR)-coactivator interactions. 2013 Bioorg. Med. Chem. Lett. pmid:23806555
De Poli M et al. Left-handed helical preference in an achiral peptide chain is induced by an L-amino acid in an N-terminal type II β-turn. 2013 J. Org. Chem. pmid:23316729
Caruso M et al. Fibrils or globules? Tuning the morphology of peptide aggregates from helical building blocks. 2013 J Phys Chem B pmid:23581652
Untiet V et al. ABC transport is inactivated by the PTS(Ntr) under potassium limitation in Rhizobium leguminosarum 3841. 2013 PLoS ONE pmid:23724079
Kaplan JM et al. Conformationally constrained functional peptide monolayers for the controlled display of bioactive carbohydrate ligands. 2013 Langmuir pmid:23782319
Ceccacci F et al. Deracemization and the first CD spectrum of a 3(10)-helical peptide made of achiral α-amino-isobutyric acid residues in a chiral membrane mimetic environment. 2013 Chem. Commun. (Camb.) pmid:24049772
Fremaux J et al. Influence of achiral units with gem-dimethyl substituents on the helical character of aliphatic oligourea foldamers. 2013 Chem. Commun. (Camb.) pmid:23862177
Vogel KR et al. Characterization of 2-(methylamino)alkanoic acid capacity to restrict blood-brain phenylalanine transport in Pah enu2 mice: preliminary findings. 2013 Mol. Genet. Metab. pmid:23999161
Panizel I et al. Eight new peptaibols from sponge-associated Trichoderma atroviride. 2013 Mar Drugs pmid:24335521
Wada S et al. Effect of Ala replacement with Aib in amphipathic cell-penetrating peptide on oligonucleotide delivery into cells. 2013 Bioorg. Med. Chem. pmid:24216093
Parween S et al. Non-natural amino acids containing peptide-capped gold nanoparticles for drug delivery application. 2013 ACS Appl Mater Interfaces pmid:23767970
Islam MS et al. Evaluation of functional groups on amino acids in cyclic tetrapeptides in histone deacetylase inhibition. 2012 Amino Acids pmid:21638021
Sopasis GJ et al. Heptanuclear heterometallic [Cu6Ln] clusters: trapping lanthanides into copper cages with artificial amino acids. 2012 Inorg Chem pmid:22548650
Demizu Y et al. Conformations of helical Aib peptides containing a pair of L-amino acid and D-amino acid. 2012 J. Pept. Sci. pmid:22619002
De Zotti M et al. Antimicrobial lipopeptaibol trichogin GA IV: role of the three Aib residues on conformation and bioactivity. 2012 Amino Acids pmid:22484376
Tsuji AB et al. Comparison of 2-amino-[3-¹¹C]isobutyric acid and 2-deoxy-2-[¹⁸F]fluoro-D-glucose in nude mice with xenografted tumors and acute inflammation. 2012 Nucl Med Commun pmid:22797465
Day JW et al. Optimization of co-agonism at GLP-1 and glucagon receptors to safely maximize weight reduction in DIO-rodents. 2012 Biopolymers pmid:23203689
Demizu Y et al. Twisted structure of a cyclic hexapeptide containing a combination of alternating L-Leu-D-Leu-Aib segments. 2012 J. Org. Chem. pmid:23006337
Huber KL et al. Inhibition of caspase-9 by stabilized peptides targeting the dimerization interface. 2012 Biopolymers pmid:23203690
Mikkola R et al. 20-Residue and 11-residue peptaibols from the fungus Trichoderma longibrachiatum are synergistic in forming Na+/K+ -permeable channels and adverse action towards mammalian cells. 2012 FEBS J. pmid:22994321
Khunweeraphong N et al. Establishment of stable cell lines with high expression of heterodimers of human 4F2hc and human amino acid transporter LAT1 or LAT2 and delineation of their differential interaction with α-alkyl moieties. 2012 J. Pharmacol. Sci. pmid:22850614
Kim GB and Kim YP Analysis of protease activity using quantum dots and resonance energy transfer. 2012 Theranostics pmid:22375154
Chi OZ et al. Effects of GABA(A) receptor blockade on regional cerebral blood flow and blood-brain barrier disruption in focal cerebral ischemia. 2011 J. Neurol. Sci. pmid:21094956
Goj A and Bittner ER Mixed quantum classical simulations of excitons in peptide helices. 2011 J Chem Phys pmid:21639483
Donoli A et al. Charge mapping in 3(10)-helical peptide chains by oxidation of the terminal ferrocenyl group. 2011 Org. Lett. pmid:21341757
Kato K et al. An efficient and expedient method for the synthesis of 11C-labeled α-aminoisobutyric acid: a tumor imaging agent potentially useful for cancer diagnosis. 2011 Bioorg. Med. Chem. Lett. pmid:21392981
Kar S et al. Formation of vesicles through solvent assisted self-assembly of hydrophobic pentapeptides: encapsulation and pH responsive release of dyes by the vesicles. 2011 Protein Pept. Lett. pmid:21443496
Elsila JE et al. Distribution and stable isotopic composition of amino acids from fungal peptaibiotics: assessing the potential for meteoritic contamination. 2011 Astrobiology pmid:21417942
Shennan DB and Thomson J Specificity of the volume-activated amino acid efflux pathway in cultured human breast cancer cells. 2011 Gen. Physiol. Biophys. pmid:21460411
Jacobsen Ø et al. Stapling of a 3(10)-helix with click chemistry. 2011 J. Org. Chem. pmid:21275402
Van den Eynden J et al. Glycine enhances microglial intracellular calcium signaling. A role for sodium-coupled neutral amino acid transporters. 2011 Pflugers Arch. pmid:21350800
Yu M et al. Methyl jasmonate-induced defense responses are associated with elevation of 1-aminocyclopropane-1-carboxylate oxidase in Lycopersicon esculentum fruit. 2011 J. Plant Physiol. pmid:21788095
Carlotto S et al. In silico interpretation of cw-ESR at 9 and 95 GHz of mono- and bis- TOAC-labeled Aib-homopeptides in fluid and frozen acetonitrile. 2011 J Phys Chem B pmid:21970372
Wada S et al. Cellular uptake of Aib-containing amphipathic helix peptide. 2011 Bioorg. Med. Chem. Lett. pmid:21875799
Porth I et al. Defense mechanisms against herbivory in Picea: sequence evolution and expression regulation of gene family members in the phenylpropanoid pathway. 2011 BMC Genomics pmid:22177423
Fletcher SP et al. Synthesis of enantiomerically enriched (R)-C-labelled 2-aminoisobutyric acid (Aib) by conformational memory in the alkylation of a derivative of L-alanine. 2011 Beilstein J Org Chem pmid:22043239
Ramapanicker R et al. Applications of propargyl esters of amino acids in solution-phase Peptide synthesis. 2011 Int J Pept pmid:21760822
Gran P and Cameron-Smith D The actions of exogenous leucine on mTOR signalling and amino acid transporters in human myotubes. 2011 BMC Physiol. pmid:21702994
Nagaraja TN et al. MRI and quantitative autoradiographic studies following bolus injections of unlabeled and (14)C-labeled gadolinium-diethylenetriaminepentaacetic acid in a rat model of stroke yield similar distribution volumes and blood-to-brain influx rate constants. 2011 NMR Biomed pmid:21674656
Lu HL et al. A calcium bioluminescence assay for functional analysis of mosquito (Aedes aegypti) and tick (Rhipicephalus microplus) G protein-coupled receptors. 2011 J Vis Exp pmid:21540818
Gao X et al. Fungal indole alkaloid biosynthesis: genetic and biochemical investigation of the tryptoquialanine pathway in Penicillium aethiopicum. 2011 J. Am. Chem. Soc. pmid:21299212
Mukherjee PK et al. Two classes of new peptaibols are synthesized by a single non-ribosomal peptide synthetase of Trichoderma virens. 2011 J. Biol. Chem. pmid:21123172