| MeSH term | MeSH ID | Detail |
|---|---|---|
| Infertility, Male | D007248 | 11 associated lipids |
| Mammary Neoplasms, Experimental | D008325 | 67 associated lipids |
| Body Weight | D001835 | 333 associated lipids |
| Precancerous Conditions | D011230 | 48 associated lipids |
| Arthritis, Experimental | D001169 | 24 associated lipids |
| Hypotension | D007022 | 41 associated lipids |
| Trypanosomiasis | D014352 | 5 associated lipids |
| Liver Diseases | D008107 | 31 associated lipids |
| Prostatic Neoplasms | D011471 | 126 associated lipids |
| Hepatic Encephalopathy | D006501 | 9 associated lipids |
2,5-diaminopentanoic acid
2,5-diaminopentanoic acid is a lipid of Fatty Acyls (FA) class. The involved functions are known as Vasodilation, Intestinal Absorption and Pinocytosis. 2,5-diaminopentanoic acid often locates in Mitochondria, Microfilaments, NADH dehydrogenase complex and respiratory chain complex III location sensu Eukarya. The associated genes with 2,5-diaminopentanoic acid are GAPDH gene and iberiotoxin.
Cross Reference
Introduction
To understand associated biological information of 2,5-diaminopentanoic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with 2,5-diaminopentanoic acid?
There are no associated biomedical information in the current reference collection.
Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with 2,5-diaminopentanoic acid
PubChem Associated disorders and diseases
What pathways are associated with 2,5-diaminopentanoic acid
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with 2,5-diaminopentanoic acid?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with 2,5-diaminopentanoic acid?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with 2,5-diaminopentanoic acid?
There are no associated biomedical information in the current reference collection.
What genes are associated with 2,5-diaminopentanoic acid?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with 2,5-diaminopentanoic acid?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with 2,5-diaminopentanoic acid
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Sherwood CL et al. | A highly potent agonist to protease-activated receptor-2 reveals apical activation of the airway epithelium resulting in Ca2+-regulated ion conductance. | 2014 | Am. J. Physiol., Cell Physiol. | pmid:25143347 |
| Dunford LJ et al. | Maternal protein-energy malnutrition during early pregnancy in sheep impacts the fetal ornithine cycle to reduce fetal kidney microvascular development. | 2014 | FASEB J. | pmid:25077559 |
| Guimarães Filho A et al. | Glutamine and ornithine alpha-ketoglutarate supplementation on malate dehydrogenases expression in hepatectomized rats. | 2014 | Acta Cir Bras | pmid:24919044 |
| Miyake M et al. | Randomised controlled trial of the effects of L-ornithine on stress markers and sleep quality in healthy workers. | 2014 | Nutr J | pmid:24889392 |
| Lee HH et al. | Hyperornithinaemia-hyperammonaemia-homocitrullinuria syndrome: a treatable genetic liver disease warranting urgent diagnosis. | 2014 | Hong Kong Med J | pmid:24473688 |
| Döring Y et al. | Neutrophils cast NETs in atherosclerosis: employing peptidylarginine deiminase as a therapeutic target. | 2014 | Circ. Res. | pmid:24625721 |
| Katagiri S et al. | OAT mutations and clinical features in two Japanese brothers with gyrate atrophy of the choroid and retina. | 2014 | Doc Ophthalmol | pmid:24429551 |
| Hwang GH and Cho JY | Enhancement of L-ornithine production by disruption of three genes encoding putative oxidoreductases in Corynebacterium glutamicum. | 2014 | J. Ind. Microbiol. Biotechnol. | pmid:24402505 |
| Ventura-Cots M et al. | Safety of ornithine phenylacetate in cirrhotic decompensated patients: an open-label, dose-escalating, single-cohort study. | 2013 Nov-Dec | J. Clin. Gastroenterol. | pmid:23751856 |
| El-Bassossy HM et al. | Arginase inhibition alleviates hypertension in the metabolic syndrome. | 2013 | Br. J. Pharmacol. | pmid:23441715 |
| Gholami M et al. | Selective regulation of nicotine and polyamines biosynthesis in tobacco cells by enantiomers of ornithine. | 2013 | Chirality | pmid:22996307 |
| Vences-Guzmán Mà et al. | Agrobacteria lacking ornithine lipids induce more rapid tumour formation. | 2013 | Environ. Microbiol. | pmid:22958119 |
| Siamwala JH et al. | L-theanine promotes nitric oxide production in endothelial cells through eNOS phosphorylation. | 2013 | J. Nutr. Biochem. | pmid:22819553 |
| Brahmajosyula M and Miyake M | Role of peptidylarginine deiminase 4 (PAD4) in pig parthenogenetic preimplantation embryonic development. | 2013 | Zygote | pmid:22793990 |
| Newman J et al. | Determination of the structure of the catabolic N-succinylornithine transaminase (AstC) from Escherichia coli. | 2013 | PLoS ONE | pmid:23484010 |
| Hol JW et al. | Effect of major and minor surgery on plasma levels of arginine, citrulline, nitric oxide metabolites, and ornithine in humans. | 2013 | Ann. Surg. | pmid:23470569 |
| North ML et al. | Increased ornithine-derived polyamines cause airway hyperresponsiveness in a mouse model of asthma. | 2013 | Am. J. Respir. Cell Mol. Biol. | pmid:23470627 |
| Zane HK and Butler A | Isolation, structure elucidation, and iron-binding properties of lystabactins, siderophores isolated from a marine Pseudoalteromonas sp. | 2013 | J. Nat. Prod. | pmid:23444833 |
| Jover-Cobos M et al. | Ornithine phenylacetate revisited. | 2013 | Metab Brain Dis | pmid:23456516 |
| Ouchi T et al. | Lysine and arginine biosyntheses mediated by a common carrier protein in Sulfolobus. | 2013 | Nat. Chem. Biol. | pmid:23434852 |
| Elms S et al. | Insights into the arginine paradox: evidence against the importance of subcellular location of arginase and eNOS. | 2013 | Am. J. Physiol. Heart Circ. Physiol. | pmid:23792682 |
| McGee WM and McLuckey SA | The ornithine effect in peptide cation dissociation. | 2013 | J Mass Spectrom | pmid:23832942 |
| Jiang LY et al. | Metabolic engineering of Corynebacterium glutamicum for increasing the production of L-ornithine by increasing NADPH availability. | 2013 | J. Ind. Microbiol. Biotechnol. | pmid:23836141 |
| Gholami M et al. | Differential effects of ornithine enantiomers on the activity of anti-oxidant enzymes, polyamines content, and growth of tobacco cells under osmotic stresses. | 2013 | Chirality | pmid:23836605 |
| Srivastava S and Ratha BK | Unique hepatic cytosolic arginase evolved independently in ureogenic freshwater air-breathing teleost, Heteropneustes fossilis. | 2013 | PLoS ONE | pmid:23840400 |
| Zanatta A et al. | Disturbance of redox homeostasis by ornithine and homocitrulline in rat cerebellum: a possible mechanism of cerebellar dysfunction in HHH syndrome. | 2013 | Life Sci. | pmid:23806752 |
| RamÃrez-Zamora S et al. | Increased erythrocytes by-products of arginine catabolism are associated with hyperglycemia and could be involved in the pathogenesis of type 2 diabetes mellitus. | 2013 | PLoS ONE | pmid:23826148 |
| Horiuchi M et al. | Ornithine ingestion improved sleep disturbances but was not associated with correction of blood tryptophan ratio in Japanese Antarctica expedition members during summer. | 2013 | Nutr Res | pmid:23827130 |
| Sailer M et al. | Increased plasma citrulline in mice marks diet-induced obesity and may predict the development of the metabolic syndrome. | 2013 | PLoS ONE | pmid:23691124 |
| Mochizuki T et al. | Quality of cardiopulmonary resuscitation affects cardioprotection by induced hypothermia at 34 °C against ischemia/reperfusion injury in a rat isolated heart model. | 2013 | Shock | pmid:23680771 |
| Andersen SM et al. | Dietary arginine affects energy metabolism through polyamine turnover in juvenile Atlantic salmon (Salmo salar). | 2013 | Br. J. Nutr. | pmid:23656796 |
| Zunić G et al. | Unilateral nephrectomy causes an early abrupt decrease in plasma arginine and simultaneous reduction in glomerular filtration rate in living kidney donors. | 2013 | Clin. Biochem. | pmid:23669210 |
| Tsiapa I et al. | Biological evaluation of an ornithine-modified (99m)Tc-labeled RGD peptide as an angiogenesis imaging agent. | 2013 | Nucl. Med. Biol. | pmid:23238128 |
| Filosto M et al. | Hyperornithinemia-hyperammonemia-homocitrullinuria (HHH) syndrome in adulthood: a rare recognizable condition. | 2013 | Neurol. Sci. | pmid:23247599 |
| Sánchez-Jiménez F et al. | Pharmacological potential of biogenic amine-polyamine interactions beyond neurotransmission. | 2013 | Br. J. Pharmacol. | pmid:23347064 |
| Romano A et al. | Three-component lysine/ornithine decarboxylation system in Lactobacillus saerimneri 30a. | 2013 | J. Bacteriol. | pmid:23316036 |
| Gu X et al. | Mathematical modelling of polyamine metabolism in bloodstream-form Trypanosoma brucei: an application to drug target identification. | 2013 | PLoS ONE | pmid:23372667 |
| Reimann M et al. | Metabolomic distinction of microvascular effects of lipoprotein apheresis--a pilot study. | 2013 | Atheroscler Suppl | pmid:23357156 |
| Srivastava S and Ratha BK | Unusual hepatic mitochondrial arginase in an Indian air-breathing teleost, Heteropneustes fossilis: purification and characterization. | 2013 | Comp. Biochem. Physiol. B, Biochem. Mol. Biol. | pmid:23195132 |
| Dadsetan S et al. | Interorgan metabolism of ornithine phenylacetate (OP)--a novel strategy for treatment of hyperammonemia. | 2013 | Biochem. Pharmacol. | pmid:23103564 |
| Berthold N et al. | Novel apidaecin 1b analogs with superior serum stabilities for treatment of infections by gram-negative pathogens. | 2013 | Antimicrob. Agents Chemother. | pmid:23114765 |
| Rimaux T et al. | A putative transport protein is involved in citrulline excretion and re-uptake during arginine deiminase pathway activity by Lactobacillus sakei. | 2013 | Res. Microbiol. | pmid:23178175 |
| Araque I et al. | Effect of ethanol and low pH on citrulline and ornithine excretion and arc gene expression by strains of Lactobacillus brevis and Pediococcus pentosaceus. | 2013 | Food Microbiol. | pmid:23122508 |
| Amelio D et al. | Effects of temperature on the nitric oxide-dependent modulation of the Frank-Starling mechanism: the fish heart as a case study. | 2013 | Comp. Biochem. Physiol., Part A Mol. Integr. Physiol. | pmid:23123761 |
| Meiswinkel TM et al. | Accelerated pentose utilization by Corynebacterium glutamicum for accelerated production of lysine, glutamate, ornithine and putrescine. | 2013 | Microb Biotechnol | pmid:23164409 |
| Pigott B et al. | On the selectivity of neuronal NOS inhibitors. | 2013 | Br. J. Pharmacol. | pmid:23072468 |
| De Bruyn T et al. | Structure-based identification of OATP1B1/3 inhibitors. | 2013 | Mol. Pharmacol. | pmid:23571415 |
| Majumdar R et al. | Ornithine: the overlooked molecule in the regulation of polyamine metabolism. | 2013 | Plant Cell Physiol. | pmid:23574701 |
| Milner SJ et al. | Staphyloferrin A as siderophore-component in fluoroquinolone-based Trojan horse antibiotics. | 2013 | Org. Biomol. Chem. | pmid:23575952 |
| LeMoine CM and Walsh PJ | Ontogeny of ornithine-urea cycle gene expression in zebrafish (Danio rerio). | 2013 | Am. J. Physiol. Regul. Integr. Comp. Physiol. | pmid:23576614 |
| El-Gharbawy AH et al. | Elevation of guanidinoacetate in newborn dried blood spots and impact of early treatment in GAMT deficiency. | 2013 | Mol. Genet. Metab. | pmid:23583224 |
| D'Antonio EL et al. | Crystal structure of arginase from Leishmania mexicana and implications for the inhibition of polyamine biosynthesis in parasitic infections. | 2013 | Arch. Biochem. Biophys. | pmid:23583962 |
| Juncosa JI et al. | Two continuous coupled assays for ornithine-δ-aminotransferase. | 2013 | Anal. Biochem. | pmid:23747282 |
| Knight JS et al. | Peptidylarginine deiminase inhibition is immunomodulatory and vasculoprotective in murine lupus. | 2013 | J. Clin. Invest. | pmid:23722903 |
| Jiang LY et al. | Metabolic evolution of Corynebacterium glutamicum for increased production of L-ornithine. | 2013 | BMC Biotechnol. | pmid:23725060 |
| Tamás P et al. | L-arginine metabolism in early-onset and late-onset pre-eclamptic pregnancies. | 2013 | Scand. J. Clin. Lab. Invest. | pmid:23777299 |
| You H et al. | Arginase inhibition mediates renal tissue protection in diabetic nephropathy by a nitric oxide synthase 3-dependent mechanism. | 2013 | Kidney Int. | pmid:23760286 |
| Whidbey C et al. | A hemolytic pigment of Group B Streptococcus allows bacterial penetration of human placenta. | 2013 | J. Exp. Med. | pmid:23712433 |
| Geraths C et al. | Synthesis and characterization of a stimulus-responsive L-ornithine-degrading hydrogel. | 2013 | J Control Release | pmid:23142579 |
| Inoue K et al. | Metabolic profiling of Alzheimer's disease brains. | 2013 | Sci Rep | pmid:23917584 |
| Raimura M et al. | Neuronal nitric oxide synthase-derived nitric oxide is involved in gastric mucosal hyperemic response to capsaicin in rats. | 2013 | Pharmacology | pmid:23920479 |
| Beckmann N et al. | Characterization of the Link between Ornithine, Arginine, Polyamine and Siderophore Metabolism in Aspergillus fumigatus. | 2013 | PLoS ONE | pmid:23825660 |
| Flynn AN et al. | Development of highly potent protease-activated receptor 2 agonists via synthetic lipid tethering. | 2013 | FASEB J. | pmid:23292071 |
| Gomis A et al. | Blockade of nociceptive sensory afferent activity of the rat knee joint by the bradykinin B2 receptor antagonist fasitibant. | 2013 | Osteoarthr. Cartil. | pmid:23973149 |
| De Francesco EM et al. | GPER mediates cardiotropic effects in spontaneously hypertensive rat hearts. | 2013 | PLoS ONE | pmid:23950890 |
| Viau KS et al. | Evidence-based treatment of guanidinoacetate methyltransferase (GAMT) deficiency. | 2013 | Mol. Genet. Metab. | pmid:24071436 |
| Romański J et al. | Selective NaNO2 recognition by a simple heteroditopic salt receptor based on L-ornithine molecular scaffold. | 2013 | Dalton Trans | pmid:24042262 |
| Ishida S et al. | Genotoxicity and subchronic oral toxicity of L-ornithine monohydrochloride. | 2013 | Regul. Toxicol. Pharmacol. | pmid:23994624 |
| Moore EK et al. | Novel mono-, di-, and trimethylornithine membrane lipids in northern wetland planctomycetes. | 2013 | Appl. Environ. Microbiol. | pmid:23995937 |
| Oya M et al. | The G protein-coupled receptor family C group 6 subtype A (GPRC6A) receptor is involved in amino acid-induced glucagon-like peptide-1 secretion from GLUTag cells. | 2013 | J. Biol. Chem. | pmid:23269670 |
| Zhan Y et al. | Biotransformation of L-ornithine from L-arginine using whole-cell recombinant arginase. | 2013 | World J. Microbiol. Biotechnol. | pmid:23700128 |
| Soszynski D et al. | Blockade of nitric oxide formation in the rat brain does not disturb development of endotoxin tolerance. | 2013 | J. Physiol. Pharmacol. | pmid:24388893 |
| Gonzalez-Juarrero M et al. | Polar lipids of Burkholderia pseudomallei induce different host immune responses. | 2013 | PLoS ONE | pmid:24260378 |
| Robinson R et al. | C4a-hydroperoxyflavin formation in N-hydroxylating flavin monooxygenases is mediated by the 2'-OH of the nicotinamide ribose of NADPâº. | 2013 | Biochemistry | pmid:24321106 |
| Jaźwińska-Kozuba A et al. | Opposite associations of plasma homoarginine and ornithine with arginine in healthy children and adolescents. | 2013 | Int J Mol Sci | pmid:24192823 |
| Sharma S et al. | Functional characterization of an ornithine cyclodeaminase-like protein of Arabidopsis thaliana. | 2013 | BMC Plant Biol. | pmid:24237637 |
| Nickla DL et al. | Nitric oxide synthase inhibitors prevent the growth-inhibiting effects of quinpirole. | 2013 | Optom Vis Sci | pmid:24061155 |
| Arinbasarova AIu et al. | [Isolation and Properties of L-Lysine-alpha-Oxidase from the Fungus Trichoderma cf. aureoviride RIFAI VKM F-4268D tion]. | 2012 Sep-Oct | Mikrobiologiia | pmid:23234070 |
| El-Bassossy HM et al. | Arginase inhibition alleviates hypertension associated with diabetes: effect on endothelial dependent relaxation and NO production. | 2012 Nov-Dec | Vascul. Pharmacol. | pmid:22281732 |
| Ferents IV et al. | [The effect of agmatine on L-arginine metabolism in erythrocytes under streptozotocin-induced diabetes in rats]. | 2012 May-Jun | Ukr Biokhim Zh (1999) | pmid:22860402 |
| Lee KS et al. | Differential effects of substrate-analogue inhibitors on nitric oxide synthase dimerization. | 2012 | Biochem. Biophys. Res. Commun. | pmid:22240022 |
| Bosch D and Saiardi A | Arginine transcriptional response does not require inositol phosphate synthesis. | 2012 | J. Biol. Chem. | pmid:22992733 |
| Uchiyama M et al. | Simple and sensitive HPLC method for the fluorometric determination of methotrexate and its major metabolites in human plasma by post-column photochemical reaction. | 2012 | Biomed. Chromatogr. | pmid:21437923 |
| Parajón-Costa BS and Baran EJ | Vibrational and electronic spectra of [Cu(L-ornithinato)2Cl2]·2H2O. | 2012 | Spectrochim Acta A Mol Biomol Spectrosc | pmid:22964244 |
| Tringham M et al. | Exploring the transcriptomic variation caused by the Finnish founder mutation of lysinuric protein intolerance (LPI). | 2012 | Mol. Genet. Metab. | pmid:22221392 |
| Currell K et al. | A-Z of nutritional supplements: dietary supplements, sports nutrition foods and ergogenic aids for health and performance - part 28. | 2012 | Br J Sports Med | pmid:22167717 |
| Knerr I et al. | Advances and challenges in the treatment of branched-chain amino/keto acid metabolic defects. | 2012 | J. Inherit. Metab. Dis. | pmid:21290185 |
| Renner AB et al. | Gyrate atrophy: clinical and genetic findings in a female without arginine-restricted diet during her first 39 years of life and report of a new OAT gene mutation. | 2012 | Doc Ophthalmol | pmid:22674428 |
| Faussner A et al. | Binding characteristics of [3H]-JSM10292: a new cell membrane-permeant non-peptide bradykinin B2 receptor antagonist. | 2012 | Br. J. Pharmacol. | pmid:22646218 |
| Yamaleyeva LM et al. | Amelioration of renal injury and oxidative stress by the nNOS inhibitor L-VNIO in the salt-sensitive mRen2.Lewis congenic rat. | 2012 | J. Cardiovasc. Pharmacol. | pmid:22370956 |
| Bensaci J et al. | An in silico model of enterocytic glutamine to citrulline conversion pathway. | 2012 | Amino Acids | pmid:22399052 |
| Polo LM et al. | New insight into the transcarbamylase family: the structure of putrescine transcarbamylase, a key catalyst for fermentative utilization of agmatine. | 2012 | PLoS ONE | pmid:22363663 |
| Barilli A et al. | Radiochemical high-performance liquid chromatography detection of arginine metabolism in human endothelial cells. | 2012 | Anal. Biochem. | pmid:22381370 |
| Kobayashi K et al. | Synthesis and application of an Nδ-acetyl-Nδ-hydroxyornithine analog: identification of novel metal complexes of deferriferrichrysin. | 2012 | Bioorg. Med. Chem. | pmid:22405596 |
| Hanssen SJ et al. | Hemolysis compromises nitric oxide-dependent vasodilatory responses in patients undergoing major cardiovascular surgery. | 2012 | Thorac Cardiovasc Surg | pmid:22411759 |
| El-Salam OI et al. | Synthesis of new macrocyclic polyamides as antimicrobial agent candidates. | 2012 | Molecules | pmid:23222868 |
| Nagasawa M et al. | Impacts of acute imipramine treatment on plasma and brain amino acid metabolism in mice given graded levels of dietary chicken protein. | 2012 | Anim. Sci. J. | pmid:23216543 |
| Cheung J et al. | Discovery of an iron-regulated citrate synthase in Staphylococcus aureus. | 2012 | Chem. Biol. | pmid:23261600 |
| Tujioka K et al. | Effect of dietary ornithine on the brain protein synthesis rate in hypophysectomized aged rats. | 2012 | J. Nutr. Sci. Vitaminol. | pmid:23327970 |
| Quitterer F et al. | Crystal structure of methylornithine synthase (PylB): insights into the pyrrolysine biosynthesis. | 2012 | Angew. Chem. Int. Ed. Engl. | pmid:22095926 |