| MeSH term | MeSH ID | Detail |
|---|---|---|
| Heart Failure, Diastolic | D054144 | 1 associated lipids |
| Paraparesis, Spastic | D020336 | 1 associated lipids |
| Opsoclonus-Myoclonus Syndrome | D053578 | 1 associated lipids |
| Lens Diseases | D007905 | 1 associated lipids |
| Chorioretinitis | D002825 | 1 associated lipids |
| Hyperargininemia | D020162 | 1 associated lipids |
| Myotonia Congenita | D009224 | 1 associated lipids |
| Laurence-Moon Syndrome | D007849 | 1 associated lipids |
| Central Nervous System Bacterial Infections | D020806 | 1 associated lipids |
| Retinal Dysplasia | D015792 | 1 associated lipids |
2,5-diaminopentanoic acid
2,5-diaminopentanoic acid is a lipid of Fatty Acyls (FA) class. The involved functions are known as Vasodilation, Intestinal Absorption and Pinocytosis. 2,5-diaminopentanoic acid often locates in Mitochondria, Microfilaments, NADH dehydrogenase complex and respiratory chain complex III location sensu Eukarya. The associated genes with 2,5-diaminopentanoic acid are GAPDH gene and iberiotoxin.
Cross Reference
Introduction
To understand associated biological information of 2,5-diaminopentanoic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with 2,5-diaminopentanoic acid?
There are no associated biomedical information in the current reference collection.
Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with 2,5-diaminopentanoic acid
PubChem Associated disorders and diseases
What pathways are associated with 2,5-diaminopentanoic acid
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with 2,5-diaminopentanoic acid?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with 2,5-diaminopentanoic acid?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with 2,5-diaminopentanoic acid?
There are no associated biomedical information in the current reference collection.
What genes are associated with 2,5-diaminopentanoic acid?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with 2,5-diaminopentanoic acid?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with 2,5-diaminopentanoic acid
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Bollans L et al. | The acyl nitroso Diels-Alder (ANDA) reaction of sorbate derivatives: an X-ray and 15N NMR study with an application to amino-acid synthesis. | 2009 | Org. Biomol. Chem. | pmid:19830306 |
| Mazzoli R et al. | Influence of ethanol, malate and arginine on histamine production of Lactobacillus hilgardii isolated from an Italian red wine. | 2009 | Amino Acids | pmid:18283413 |
| DomÃnguez-Vega E et al. | Fast derivatization of the non-protein amino acid ornithine with FITC using an ultrasound probe prior to enantiomeric determination in food supplements by EKC. | 2009 | Electrophoresis | pmid:19229843 |
| Martens-Lobenhoffer J et al. | Identification and quantification of the atypical metabolite ornithine-lactam in human plasma by liquid chromatography-tandem mass spectrometry (LC-MS/MS). | 2009 | J. Chromatogr. B Analyt. Technol. Biomed. Life Sci. | pmid:19213615 |
| Chiang HT et al. | Neuronal nitric oxide synthase activation is involved in insulin-mediated cardiovascular effects in the nucleus tractus solitarii of rats. | 2009 | Neuroscience | pmid:19167463 |
| Tessa A et al. | Identification of novel mutations in the SLC25A15 gene in hyperornithinemia-hyperammonemia-homocitrullinuria (HHH) syndrome: a clinical, molecular, and functional study. | 2009 | Hum. Mutat. | pmid:19242930 |
| Liu P et al. | Memory-related changes in L-citrulline and agmatine in the rat brain. | 2009 | Hippocampus | pmid:19173225 |
| Fonknechten N et al. | A conserved gene cluster rules anaerobic oxidative degradation of L-ornithine. | 2009 | J. Bacteriol. | pmid:19251850 |
| Zhang GX et al. | Role of neuronal NO synthase in regulating vascular superoxide levels and mitogen-activated protein kinase phosphorylation. | 2009 | Cardiovasc. Res. | pmid:18987049 |
| Zhang X et al. | Characterization of ornithine and glutamine lipids extracted from cell membranes of Rhodobacter sphaeroides. | 2009 | J. Am. Soc. Mass Spectrom. | pmid:18835523 |
| Becker T et al. | The L-arginine/NO pathway in end-stage liver disease and during orthotopic liver and kidney transplantation: biological and analytical ramifications. | 2009 | Nitric Oxide | pmid:18948222 |
| Morris PG and Fornier MN | Ixabepilone and other epothilones: microtubule-targeting agents for metastatic breast cancer. | 2009 | Clin Adv Hematol Oncol | pmid:19367253 |
| Meneely KM et al. | Kinetic mechanism of ornithine hydroxylase (PvdA) from Pseudomonas aeruginosa: substrate triggering of O2 addition but not flavin reduction. | 2009 | Biochemistry | pmid:19368334 |
| Kalamaki MS et al. | Over-expression of a tomato N-acetyl-L-glutamate synthase gene (SlNAGS1) in Arabidopsis thaliana results in high ornithine levels and increased tolerance in salt and drought stresses. | 2009 | J. Exp. Bot. | pmid:19357433 |
| Lu XM et al. | The opposite roles of nNOS in cardiac ischemia-reperfusion-induced injury and in ischemia preconditioning-induced cardioprotection in mice. | 2009 | J Physiol Sci | pmid:19340535 |
| Steinle A et al. | Metabolic engineering of Saccharomyces cerevisiae for production of novel cyanophycins with an extended range of constituent amino acids. | 2009 | Appl. Environ. Microbiol. | pmid:19346356 |
| Camacho JA and Rioseco-Camacho N | The human and mouse SLC25A29 mitochondrial transporters rescue the deficient ornithine metabolism in fibroblasts of patients with the hyperornithinemia-hyperammonemia-homocitrullinuria (HHH) syndrome. | 2009 | Pediatr. Res. | pmid:19287344 |
| Matsui D et al. | A periplasmic, pyridoxal-5'-phosphate-dependent amino acid racemase in Pseudomonas taetrolens. | 2009 | Appl. Microbiol. Biotechnol. | pmid:19300994 |
| Little JA et al. | Hematologic, biochemical, and cardiopulmonary effects of L-arginine supplementation or phosphodiesterase 5 inhibition in patients with sickle cell disease who are on hydroxyurea therapy. | 2009 | Eur. J. Haematol. | pmid:19215288 |
| Olszewski KL et al. | Host-parasite interactions revealed by Plasmodium falciparum metabolomics. | 2009 | Cell Host Microbe | pmid:19218089 |
| Lee SY et al. | The effect of ArgR-DNA binding affinity on ornithine production in Corynebacterium glutamicum. | 2009 | Curr. Microbiol. | pmid:19688381 |
| Cheung J et al. | Molecular characterization of staphyloferrin B biosynthesis in Staphylococcus aureus. | 2009 | Mol. Microbiol. | pmid:19775248 |
| Heemstra JR et al. | Enzymatic tailoring of ornithine in the biosynthesis of the Rhizobium cyclic trihydroxamate siderophore vicibactin. | 2009 | J. Am. Chem. Soc. | pmid:19778043 |
| Vrancken G et al. | Environmental pH determines citrulline and ornithine release through the arginine deiminase pathway in Lactobacillus fermentum IMDO 130101. | 2009 | Int. J. Food Microbiol. | pmid:19732985 |
| Xue B et al. | Protective actions of estrogen on angiotensin II-induced hypertension: role of central nitric oxide. | 2009 | Am. J. Physiol. Heart Circ. Physiol. | pmid:19734362 |
| Yemisci M et al. | Pericyte contraction induced by oxidative-nitrative stress impairs capillary reflow despite successful opening of an occluded cerebral artery. | 2009 | Nat. Med. | pmid:19718040 |
| Cialdai C et al. | Effect of Intra-articular 4-(S)-amino-5-(4-{4-[2,4-dichloro-3-(2,4-dimethyl-8-quinolyloxymethyl)phenylsulfonamido]-tetrahydro-2H-4-pyranylcarbonyl} piperazino)-5-oxopentyl](trimethyl)ammonium chloride hydrochloride (MEN16132), a kinin B2 receptor antagonist, on nociceptive response in monosodium iodoacetate-induced experimental osteoarthritis in rats. | 2009 | J. Pharmacol. Exp. Ther. | pmid:19745108 |
| Vrancken G et al. | The arginine deiminase pathway of Lactobacillus fermentum IMDO 130101 responds to growth under stress conditions of both temperature and salt. | 2009 | Food Microbiol. | pmid:19747605 |
| Mukai A et al. | Novel siderophore, JBIR-16, isolated from Nocardia tenerifensis NBRC 101015. | 2009 | J. Antibiot. | pmid:19696806 |
| Liu P et al. | Age-related changes in arginine and its metabolites in memory-associated brain structures. | 2009 | Neuroscience | pmid:19699269 |
| Nakadate Y et al. | The formation of argpyrimidine, a methylglyoxal-arginine adduct, in the nucleus of neural cells. | 2009 | Biochem. Biophys. Res. Commun. | pmid:19014907 |
| Balakrishnan T and Ramamurthi K | Crystal growth, structural, optical, mechanical and thermal properties of a new nonlinear optical single crystal: L-Ornithine monohydrochloride. | 2009 | Spectrochim Acta A Mol Biomol Spectrosc | pmid:19046923 |
| Cotton JL et al. | Identification and characterization of the Staphylococcus aureus gene cluster coding for staphyloferrin A. | 2009 | Biochemistry | pmid:19138128 |
| Huntington GB et al. | Urea metabolism in beef steers fed tall fescue, orchardgrass, or gamagrass hays. | 2009 | J. Anim. Sci. | pmid:19098251 |
| MartÃnez-Girón AB et al. | Development of an in-capillary derivatization method by CE for the determination of chiral amino acids in dietary supplements and wines. | 2009 | Electrophoresis | pmid:19156767 |
| Larsen FS and Wendon J | Alternative pathway therapy for hyperammonemia in liver failure. | 2009 | Hepatology | pmid:19441099 |
| Meini S et al. | Pharmacological characterization of the bradykinin B2 receptor antagonist MEN16132 in rat in vitro bioassays. | 2009 | Eur. J. Pharmacol. | pmid:19445925 |
| Bousová I et al. | Glycation of aspartate aminotransferase by methylglyoxal, effect of hydroxycitric and uric acid. | 2009 | Mol. Cell. Biochem. | pmid:19449196 |
| Pereira CI et al. | Weissella halotolerans W22 combines arginine deiminase and ornithine decarboxylation pathways and converts arginine to putrescine. | 2009 | J. Appl. Microbiol. | pmid:19486212 |
| Foster JM et al. | PP2B-dependent NO production in the medullary thick ascending limb during diabetes. | 2009 | Am. J. Physiol. Renal Physiol. | pmid:19458119 |
| Wang W et al. | Chemical and biological characterization of siderophore produced by the marine-derived Aureobasidium pullulans HN6.2 and its antibacterial activity. | 2009 | Biometals | pmid:19459055 |
| Durand JM and Björk GR | Metabolic control through ornithine and uracil of epithelial cell invasion by Shigella flexneri. | 2009 | Microbiology (Reading, Engl.) | pmid:19460819 |
| Tang WH et al. | Diminished global arginine bioavailability and increased arginine catabolism as metabolic profile of increased cardiovascular risk. | 2009 | J. Am. Coll. Cardiol. | pmid:19477356 |
| Ytrebø LM et al. | L-ornithine phenylacetate attenuates increased arterial and extracellular brain ammonia and prevents intracranial hypertension in pigs with acute liver failure. | 2009 | Hepatology | pmid:19554542 |
| Osago H et al. | Precursor ion scanning and sequencing of arginine-ADP-ribosylated peptide by mass spectrometry. | 2009 | Anal. Biochem. | pmid:19560435 |
| Qi L et al. | Chiral ligand-exchange CE assays for separation of amino acid enantiomers and determination of enzyme kinetic constant. | 2009 | Electrophoresis | pmid:19569124 |
| Wang Z et al. | Targeted metabolomic evaluation of arginine methylation and cardiovascular risks: potential mechanisms beyond nitric oxide synthase inhibition. | 2009 | Arterioscler. Thromb. Vasc. Biol. | pmid:19542023 |
| Tanaka R and Oda M | Cyclic dipeptide of D-ornithine obtained from the dobsonfly, Protohermes grandis Thunberg. | 2009 | Biosci. Biotechnol. Biochem. | pmid:19584563 |
| Amaral AU et al. | Evidence that the major metabolites accumulating in hyperornithinemia-hyperammonemia-homocitrullinuria syndrome induce oxidative stress in brain of young rats. | 2009 | Int. J. Dev. Neurosci. | pmid:19683047 |
| Morini C et al. | Retinal degeneration. | 2009 | Ophthalmology | pmid:19651321 |
| Meaume S et al. | Efficacy and safety of ornithine alpha-ketoglutarate in heel pressure ulcers in elderly patients: results of a randomized controlled trial. | 2009 | J Nutr Health Aging | pmid:19621198 |
| Brosnan ME and Brosnan JT | Hepatic glutamate metabolism: a tale of 2 hepatocytes. | 2009 | Am. J. Clin. Nutr. | pmid:19625684 |
| Wang Y et al. | Developing dual and specific inhibitors of dimethylarginine dimethylaminohydrolase-1 and nitric oxide synthase: toward a targeted polypharmacology to control nitric oxide. | 2009 | Biochemistry | pmid:19663506 |
| Viegas CM et al. | Experimental evidence that ornithine and homocitrulline disrupt energy metabolism in brain of young rats. | 2009 | Brain Res. | pmid:19616520 |
| Laberge T et al. | Effects of crowding on ornithine-urea cycle enzyme mRNA expression and activity in gulf toadfish (Opsanus beta). | 2009 | J. Exp. Biol. | pmid:19617432 |
| Beasley FC et al. | Characterization of staphyloferrin A biosynthetic and transport mutants in Staphylococcus aureus. | 2009 | Mol. Microbiol. | pmid:19400778 |
| Davies NA et al. | L-ornithine and phenylacetate synergistically produce sustained reduction in ammonia and brain water in cirrhotic rats. | 2009 | Hepatology | pmid:19437490 |
| O'Rourke DJ et al. | Guanidinoacetate methyltransferase (GAMT) deficiency: late onset of movement disorder and preserved expressive language. | 2009 | Dev Med Child Neurol | pmid:19388150 |
| Reguera RM et al. | Leishmania major lacking arginase (ARG) are auxotrophic for polyamines but retain infectivity to susceptible BALB/c mice. | 2009 | Mol. Biochem. Parasitol. | pmid:19393161 |
| Jin H | Arginine bi-directional translocation and breakdown into ornithine along the arbuscular mycorrhizal mycelium. | 2009 | Sci. China, C, Life Sci. | pmid:19381464 |
| DomÃnguez-Vega E et al. | Development of a CE-ESI-ITMS method for the enantiomeric determination of the non-protein amino acid ornithine. | 2009 | Electrophoresis | pmid:19384985 |
| Naito Y et al. | Impaired gastric ulcer healing in diabetic mice: role of methylglyoxal. | 2009 | J. Physiol. Pharmacol. | pmid:20388955 |
| Kalamaki MS et al. | Can ornithine accumulation modulate abiotic stress tolerance in Arabidopsis? | 2009 | Plant Signal Behav | pmid:19901538 |
| Stevens LA et al. | ADP-ribosylation of human defensin HNP-1 results in the replacement of the modified arginine with the noncoded amino acid ornithine. | 2009 | Proc. Natl. Acad. Sci. U.S.A. | pmid:19897717 |
| Hernández-Morales A et al. | Transcriptional profile of Pseudomonas syringae pv. phaseolicola NPS3121 in response to tissue extracts from a susceptible Phaseolus vulgaris L. cultivar. | 2009 | BMC Microbiol. | pmid:20003402 |
| Bellucci F et al. | Novel effects mediated by bradykinin and pharmacological characterization of bradykinin B2 receptor antagonism in human synovial fibroblasts. | 2009 | Br. J. Pharmacol. | pmid:20050188 |
| Cowled PA et al. | Simvastatin plus nitric oxide synthase inhibition modulates remote organ damage following skeletal muscle ischemia-reperfusion injury. | 2008 May-Jun | J Invest Surg | pmid:18569431 |
| Kocheva KV and Georgiev GI | Changes in foliar proline concentration of osmotically stressed barley. | 2008 Jan-Feb | Z. Naturforsch., C, J. Biosci. | pmid:18386497 |
| Ostera G et al. | Plasmodium falciparum: food vacuole localization of nitric oxide-derived species in intraerythrocytic stages of the malaria parasite. | 2008 | Exp. Parasitol. | pmid:18504040 |
| Moinard C et al. | Dose-ranging effects of citrulline administration on plasma amino acids and hormonal patterns in healthy subjects: the Citrudose pharmacokinetic study. | 2008 | Br. J. Nutr. | pmid:17953788 |
| MartÃnez-Girón AB et al. | Enantiomeric separation of ornithine in complex mixtures of amino acids by EKC with off-line derivatization with 6-aminoquinolyl-N-hydroxysuccinimidyl carbamate. | 2008 | J. Chromatogr. B Analyt. Technol. Biomed. Life Sci. | pmid:18599371 |
| Hwang JH et al. | Effect of increased glutamate availability on L-ornithine production in Corynebacterium glutamicum. | 2008 | J. Microbiol. Biotechnol. | pmid:18467864 |
| Rakonczay Z et al. | A new severe acute necrotizing pancreatitis model induced by L-ornithine in rats. | 2008 | Crit. Care Med. | pmid:18594222 |
| van Westerloo DJ | The better the model, the nearer the cure. | 2008 | Crit. Care Med. | pmid:18594236 |
| Sreejayan N et al. | Antioxidant properties of argpyrimidine. | 2008 | Eur. J. Pharmacol. | pmid:18692042 |
| Yemisci M et al. | Statin potentiates human platelet eNOS activity without enhancing eNOS mRNA and protein levels. | 2008 | Cerebrovasc. Dis. | pmid:18628618 |
| Florian C et al. | Murine Müller cells are progenitor cells for neuronal cells and fibrous tissue cells. | 2008 | Biochem. Biophys. Res. Commun. | pmid:18619415 |
| Sosroseno W et al. | The effect of nitric oxide on the production of cyclic AMP by a human osteoblast (HOS) cell line stimulated with hydroxyapatite. | 2008 | Biomed. Pharmacother. | pmid:17988826 |
| Sosroseno W et al. | The role of nitric oxide on the proliferation of a human osteoblast cell line stimulated with hydroxyapatite. | 2008 | J Oral Implantol | pmid:18780564 |
| Palm F et al. | Reduced nitric oxide in diabetic kidneys due to increased hepatic arginine metabolism: implications for renomedullary oxygen availability. | 2008 | Am. J. Physiol. Renal Physiol. | pmid:17942569 |
| Solomon VR et al. | Synthesis and antimalarial activity of novel side chain modified antimalarial agents derived from 4-aminoquinoline. | 2008 | Med Chem | pmid:18782041 |
| Senger RS and Papoutsakis ET | Genome-scale model for Clostridium acetobutylicum: Part I. Metabolic network resolution and analysis. | 2008 | Biotechnol. Bioeng. | pmid:18767192 |
| Chaitoff KA et al. | Effects of endothelial NOS antagonism within the periaqueductal gray on cardiovascular responses and neurotransmission during mechanical, heat, and cold nociception. | 2008 | Brain Res. | pmid:18725209 |
| Imperi F et al. | Membrane-association determinants of the omega-amino acid monooxygenase PvdA, a pyoverdine biosynthetic enzyme from Pseudomonas aeruginosa. | 2008 | Microbiology (Reading, Engl.) | pmid:18757814 |
| Stuehlinger MC et al. | Letter by Stuehlinger et al regarding article, "Metabolic profiling of arginine and nitric oxide pathways predicts hemodynamic abnormalities and mortality in patients with cardiogenic shock after acute myocardial infarction". | 2008 | Circulation | pmid:18765383 |
| Mohamed SA et al. | Fasciola gigantica: enzymes of the ornithine-proline-glutamate pathway--characterization of delta1-pyrroline-5-carboxylate dehydrogenase. | 2008 | Exp. Parasitol. | pmid:17655846 |
| van de Poll MC et al. | Elevated plasma arginase-1 does not affect plasma arginine in patients undergoing liver resection. | 2008 | Clin. Sci. | pmid:17708746 |
| Al-Hassnan ZN et al. | Hyperornithinemia-hyperammonemia-homocitrullinuria syndrome with stroke-like imaging presentation: clinical, biochemical and molecular analysis. | 2008 | J. Neurol. Sci. | pmid:17825324 |
| Biswas A et al. | Chemical modulation of the chaperone function of human alphaA-crystallin. | 2008 | J. Biochem. | pmid:18344542 |
| Adourian A et al. | Correlation network analysis for data integration and biomarker selection. | 2008 | Mol Biosyst | pmid:18437268 |
| Maarsingh H et al. | Arginase and pulmonary diseases. | 2008 | Naunyn Schmiedebergs Arch. Pharmacol. | pmid:18437360 |
| Funck D et al. | Ornithine-delta-aminotransferase is essential for arginine catabolism but not for proline biosynthesis. | 2008 | BMC Plant Biol. | pmid:18419821 |
| Mengel A et al. | Synthesis and structural study of cyclic 5-aminovaleric acid-linked beta-Ala-beta-Ala dipeptides. | 2008 | Bioorg. Med. Chem. Lett. | pmid:18682325 |
| Barbul A | Proline precursors to sustain Mammalian collagen synthesis. | 2008 | J. Nutr. | pmid:18806118 |
| Okemoto K et al. | The preparation of a lipidic endotoxin affects its biological activities. | 2008 | Biol. Pharm. Bull. | pmid:18827361 |
| Iyamu EW et al. | A colorimetric microplate assay method for high-throughput analysis of arginase activity in vitro. | 2008 | Anal. Biochem. | pmid:18789882 |
| Debray FG et al. | Phenotypic variability among patients with hyperornithinaemia-hyperammonaemia-homocitrullinuria syndrome homozygous for the delF188 mutation in SLC25A15. | 2008 | J. Med. Genet. | pmid:18978333 |
| Sugino T et al. | L-ornithine supplementation attenuates physical fatigue in healthy volunteers by modulating lipid and amino acid metabolism. | 2008 | Nutr Res | pmid:19083482 |
| Scholl-Bürgi S et al. | Amino acids in CSF and plasma in hyperammonaemic coma due to arginase1 deficiency. | 2008 | J. Inherit. Metab. Dis. | pmid:19052914 |
| Alexander JW et al. | Influence of long chain polyunsaturated fatty acids and ornithine concentrations on complications after renal transplant. | 2008 | Exp Clin Transplant | pmid:18816238 |