| MeSH term | MeSH ID | Detail |
|---|---|---|
| Uremia | D014511 | 33 associated lipids |
| Stomach Ulcer | D013276 | 75 associated lipids |
| Kidney Failure, Chronic | D007676 | 51 associated lipids |
| Diabetes Mellitus | D003920 | 90 associated lipids |
| Adenocarcinoma | D000230 | 166 associated lipids |
| Lupus Erythematosus, Systemic | D008180 | 43 associated lipids |
| Lung Neoplasms | D008175 | 171 associated lipids |
| Wounds and Injuries | D014947 | 20 associated lipids |
| Burns | D002056 | 34 associated lipids |
| Adenoma, Islet Cell | D007516 | 7 associated lipids |
2,5-diaminopentanoic acid
2,5-diaminopentanoic acid is a lipid of Fatty Acyls (FA) class. The involved functions are known as Vasodilation, Intestinal Absorption and Pinocytosis. 2,5-diaminopentanoic acid often locates in Mitochondria, Microfilaments, NADH dehydrogenase complex and respiratory chain complex III location sensu Eukarya. The associated genes with 2,5-diaminopentanoic acid are GAPDH gene and iberiotoxin.
Cross Reference
Introduction
To understand associated biological information of 2,5-diaminopentanoic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with 2,5-diaminopentanoic acid?
There are no associated biomedical information in the current reference collection.
Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with 2,5-diaminopentanoic acid
PubChem Associated disorders and diseases
What pathways are associated with 2,5-diaminopentanoic acid
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with 2,5-diaminopentanoic acid?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
Loading... please refresh the page if content is not showing up.
What functions are associated with 2,5-diaminopentanoic acid?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with 2,5-diaminopentanoic acid?
There are no associated biomedical information in the current reference collection.
What genes are associated with 2,5-diaminopentanoic acid?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with 2,5-diaminopentanoic acid?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with 2,5-diaminopentanoic acid
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| pmid: | ||||
| Lemieux B et al. | Amino acid metabolism in Friedreich's ataxia. | 1976 | Can J Neurol Sci | pmid:1000424 |
| Weathers PJ et al. | Arginine catabolism in Aphanocapsa 6308. | 1978 | Arch. Microbiol. | pmid:100070 |
| Idle JR et al. | The conjugation of arylacetic acids in the pigeon compared with the hen. | 1976 | Biochem. Soc. Trans. | pmid:1001621 |
| Moroder L et al. | [1-Adamanty fluoroformate, a useful reagent in peptide chemistry (author's transl)]. | 1976 | Hoppe-Seyler's Z. Physiol. Chem. | pmid:1002131 |
| Kawai Y et al. | A typical bacterial ornithine-containing lipid Nalpha-(D)-[3-(hexadecanoyloxy)hexadecanoyl]-ornithine is a strong stimulant for macrophages and a useful adjuvant. | 1999 | FEMS Immunol. Med. Microbiol. | pmid:10030549 |
| Borcić O and Straus B | Separation of arginase isoenzymes from human tissues by agar gel electrophoresis. | 1976 | J. Clin. Chem. Clin. Biochem. | pmid:1003114 |
| Hu CA et al. | Molecular enzymology of mammalian Delta1-pyrroline-5-carboxylate synthase. Alternative splice donor utilization generates isoforms with different sensitivity to ornithine inhibition. | 1999 | J. Biol. Chem. | pmid:10037775 |
| Storch KF et al. | Car: a cytoplasmic sensor responsible for arginine chemotaxis in the archaeon Halobacterium salinarum. | 1999 | EMBO J. | pmid:10064582 |
| Guillén M et al. | Reference values of urinary excretion of cystine and dibasic aminoacids: classification of patients with cystinuria in the Valencian Community, Spain. | 1999 | Clin. Biochem. | pmid:10074888 |
| Jaeken J et al. | On amino acid and ammonia metabolism in childhood hypothyroidism. | 1976 Jul-Sep | Acta Paediatr Belg | pmid:1007917 |
| Briggs S and Freedland RA | Effect of ornithine and lactate on urea synthesis in isolated hepatocytes. | 1976 | Biochem. J. | pmid:1008850 |
| Thoden JB et al. | The structure of carbamoyl phosphate synthetase determined to 2.1 A resolution. | 1999 | Acta Crystallogr. D Biol. Crystallogr. | pmid:10089390 |
| Rosowsky A | PT523 and other aminopterin analogs with a hemiphthaloyl-L-ornithine side chain: exceptionally tight-binding inhibitors of dihydrofolate reductase which are transported by the reduced folate carrier but cannot form polyglutamates. | 1999 | Curr. Med. Chem. | pmid:10101216 |
| Shinners EN and Catlin BW | Arginine biosynthesis in Neisseria gonorrhoeae: enzymes catalyzing the formation of ornithine and citrulline. | 1978 | J. Bacteriol. | pmid:101509 |
| Prins HA et al. | Reduced arginine plasma levels are the drive for arginine production by the kidney in the rat. | 1999 | Shock | pmid:10188773 |
| Bewley MC et al. | Crystal structures of Bacillus caldovelox arginase in complex with substrate and inhibitors reveal new insights into activation, inhibition and catalysis in the arginase superfamily. | 1999 | Structure | pmid:10196128 |
| Kenklies J et al. | Proline biosynthesis from L-ornithine in Clostridium sticklandii: purification of delta1-pyrroline-5-carboxylate reductase, and sequence and expression of the encoding gene, proC. | 1999 | Microbiology (Reading, Engl.) | pmid:10220161 |
| Hayase K and Yoshida A | Role of ornithine in the N-acetylglutamate turnover in the liver of rats. | 1999 | Biosci. Biotechnol. Biochem. | pmid:10227137 |
| Jakoby M et al. | Nitrogen regulation in Corynebacterium glutamicum: isolation of genes involved and biochemical characterization of corresponding proteins. | 1999 | FEMS Microbiol. Lett. | pmid:10227160 |
| Tucker EM | Some physiological aspects of genetic variation in the blood of sheep. | 1976 | Anim Blood Groups Biochem Genet | pmid:1023778 |
| Mergeay M et al. | Expression of Escherichia coli K-12 arginine genes in Pseudomonas fluorescens. | 1978 | J. Bacteriol. | pmid:102635 |
| Uriarte M et al. | The carbamoyl-phosphate synthetase of Pyrococcus furiosus is enzymologically and structurally a carbamate kinase. | 1999 | J. Biol. Chem. | pmid:10347186 |
| Roch-Arveiller M et al. | Ornithine alpha-ketoglutarate counteracts the decrease of liver cytochrome P-450 content in burned rats. | 1999 | Nutrition | pmid:10355851 |
| Bender CL et al. | Pseudomonas syringae phytotoxins: mode of action, regulation, and biosynthesis by peptide and polyketide synthetases. | 1999 | Microbiol. Mol. Biol. Rev. | pmid:10357851 |
| Arena ME et al. | Arginine dihydrolase pathway in Lactobacillus plantarum from orange. | 1999 | Int. J. Food Microbiol. | pmid:10359490 |
| Camacho JA et al. | Hyperornithinaemia-hyperammonaemia-homocitrullinuria syndrome is caused by mutations in a gene encoding a mitochondrial ornithine transporter. | 1999 | Nat. Genet. | pmid:10369256 |
| Moinard C et al. | Phagocyte functions in stressed rats: comparison of modulation by glutamine, arginine and ornithine 2-oxoglutarate. | 1999 | Clin. Sci. | pmid:10369794 |
| Salvatore F and Cimino F | [Biochemical mechanisms of action of catalyzers of ureogenesis and their use in human therapy]. | 1976 | Recenti Prog Med | pmid:1037141 |
| Oya T et al. | Methylglyoxal modification of protein. Chemical and immunochemical characterization of methylglyoxal-arginine adducts. | 1999 | J. Biol. Chem. | pmid:10373458 |
| Cymeryng CB et al. | Effects of L-arginine in rat adrenal cells: involvement of nitric oxide synthase. | 1999 | Endocrinology | pmid:10385387 |
| Jakubowski H | Misacylation of tRNALys with noncognate amino acids by lysyl-tRNA synthetase. | 1999 | Biochemistry | pmid:10387054 |
| Slatter DA et al. | Reactions of lipid-derived malondialdehyde with collagen. | 1999 | J. Biol. Chem. | pmid:10391905 |
| Voellmy R and Leisinger T | Regulation of enzyme synthesis in the arginine biosynthetic pathway of Pseudomonas aeruginosa. | 1978 | J. Gen. Microbiol. | pmid:103997 |
| Yamada K et al. | Preparation and properties of novel gramicidin S analogs possessing a tri-, tetra- or pentamethylene bridge between ornithine side chains. | 1999 | J. Pept. Res. | pmid:10408334 |
| Ushmorov A et al. | Differential reconstitution of mitochondrial respiratory chain activity and plasma redox state by cysteine and ornithine in a model of cancer cachexia. | 1999 | Cancer Res. | pmid:10416620 |
| Indiveri C et al. | The purified and reconstituted ornithine/citrulline carrier from rat liver mitochondria catalyses a second transport mode: ornithine+/H+ exchange. | 1999 | Biochem. J. | pmid:10417335 |
| Yang H et al. | Whole-protein-based enteral formula stimulates intestinal ornithine decarboxylase activity more than single amino acids but does not affect mucosal adenosine triphosphate content in early postsurgical refeeding. | 1999 Jul-Aug | JPEN J Parenter Enteral Nutr | pmid:10421389 |
| Dvorák M et al. | High-molecular weight HPMA copolymer-adriamycin conjugates. | 1999 | J Control Release | pmid:10425337 |
| Takatsuka Y et al. | Novel characteristics of Selenomonas ruminantium lysine decarboxylase capable of decarboxylating both L-lysine and L-ornithine. | 1999 | Biosci. Biotechnol. Biochem. | pmid:10427692 |
| Lederer MO and Bühler HP | Cross-linking of proteins by Maillard processes--characterization and detection of a lysine-arginine cross-link derived from D-glucose. | 1999 | Bioorg. Med. Chem. | pmid:10428377 |
| Peters H et al. | From rats to man: a perspective on dietary L-arginine supplementation in human renal disease. | 1999 | Nephrol. Dial. Transplant. | pmid:10435871 |
| Cynober LA | The use of alpha-ketoglutarate salts in clinical nutrition and metabolic care. | 1999 | Curr Opin Clin Nutr Metab Care | pmid:10453328 |
| Christopher R et al. | Hyperornithinaemia associated with gyrate atrophy of the choroid and retina: two cases from India. | 1999 | Ann. Clin. Biochem. | pmid:10456218 |
| McDuffie JE et al. | 5-hydroxytryptamine evokes endothelial nitric oxide synthase activation in bovine aortic endothelial cell cultures. | 1999 | Proc. Soc. Exp. Biol. Med. | pmid:10460702 |
| Belitsky BR and Sonenshein AL | An enhancer element located downstream of the major glutamate dehydrogenase gene of Bacillus subtilis. | 1999 | Proc. Natl. Acad. Sci. U.S.A. | pmid:10468601 |
| Rosowsky A et al. | 5-deazafolate analogues with a rotationally restricted glutamate or ornithine side chain: synthesis and binding interaction with folylpolyglutamate synthetase. | 1999 | J. Med. Chem. | pmid:10479284 |
| Kayanoki Y et al. | Reduced nitric oxide production by L-arginine deficiency in lysinuric protein intolerance exacerbates intravascular coagulation. | 1999 | Metab. Clin. Exp. | pmid:10484053 |
| Bryk R et al. | Studies of neuronal nitric oxide synthase inactivation by diverse suicide inhibitors. | 1999 | Arch. Biochem. Biophys. | pmid:10486143 |
| Le Boucher J et al. | Modulation of immune response with ornithine A-ketoglutarate in burn injury: an arginine or glutamine dependency? | 1999 | Nutrition | pmid:10501291 |
| Kraus H et al. | Effects of arginine infusion in infants: increased urea synthesis associated with unchanged ammonia blood levels. | 1976 | Metab. Clin. Exp. | pmid:10505 |
| Kobayashi N et al. | Dipeptides containing L-arginine analogs: new isozyme-selective inhibitors of nitric oxide synthase. | 1999 | Biol. Pharm. Bull. | pmid:10513616 |
| Li MX et al. | Aberrations of ammonia metabolism in ornithine carbamoyltransferase-deficient spf-ash mice and their prevention by treatment with urea cycle intermediate amino acids and an ornithine aminotransferase inactivator. | 1999 | Biochim. Biophys. Acta | pmid:10524224 |
| Presle N et al. | Cartilage protection by nitric oxide synthase inhibitors after intraarticular injection of interleukin-1beta in rats. | 1999 | Arthritis Rheum. | pmid:10524680 |
| Thaller MC et al. | Maltose ornithine iron medium: a new diagnostic test for Enterobacteriaceae. | 1976 Nov-Dec | Nuovi Ann Ig Microbiol | pmid:1052788 |
| Tang F and Hughes JA | Synthesis of a single-tailed cationic lipid and investigation of its transfection. | 1999 | J Control Release | pmid:10528072 |
| Chen M and Nuttall KL | Identifying delayed separation in plasma homocysteine specimens. | 1999 Oct-Dec | Ann. Clin. Lab. Sci. | pmid:10528832 |
| Ulhaq S et al. | Heterocyclic analogues of L-citrulline as inhibitors of the isoforms of nitric oxide synthase (NOS) and identification of N(delta)-(4,5-dihydrothiazol-2-yl)ornithine as a potent inhibitor. | 1999 | Bioorg. Med. Chem. | pmid:10530926 |
| Walters JD et al. | Mechanisms of fluoroquinolone transport by human neutrophils. | 1999 | Antimicrob. Agents Chemother. | pmid:10543751 |
| Carvajal N et al. | Chemical modification and site-directed mutagenesis of human liver arginase: evidence that the imidazole group of histidine-141 is not involved in substrate binding. | 1999 | Arch. Biochem. Biophys. | pmid:10545206 |
| Sawada H et al. | Phylogenetic analysis of Pseudomonas syringae pathovars suggests the horizontal gene transfer of argK and the evolutionary stability of hrp gene cluster. | 1999 | J. Mol. Evol. | pmid:10552044 |
| Boschin G et al. | Optimization of the synthesis of the cross-linked amino acid ornithinoalanine and nuclear magnetic resonance characterization of lysinoalanine and ornithinoalanine. | 1999 | J. Agric. Food Chem. | pmid:10552395 |
| Groth I et al. | Ornithinicoccus hortensis gen. nov., sp. nov., a soil actinomycete which contains L-ornithine. | 1999 | Int. J. Syst. Bacteriol. | pmid:10555353 |
| Waterson JG | Potentiation of vascular responses to catecholamines by POR-8. | 1975 | J. Dent. Res. | pmid:1055745 |
| De Bandt JP and Cynober LA | Amino acids with anabolic properties. | 1998 | Curr Opin Clin Nutr Metab Care | pmid:10565359 |
| Oratz M et al. | Protein synthesis in the hepatocyte. | 1975 | Ann. N. Y. Acad. Sci. | pmid:1056737 |
| Salerno C et al. | Determination of urinary orotic acid and uracil by capillary zone electrophoresis. | 1999 | J. Chromatogr. B Biomed. Sci. Appl. | pmid:10574204 |
| Trier K et al. | Biochemical and ultrastructural changes in rabbit sclera after treatment with 7-methylxanthine, theobromine, acetazolamide, or L-ornithine. | 1999 | Br J Ophthalmol | pmid:10574816 |
| Jeevanandam M | Immune modulation with OKG supplementation in burn injury. | 1999 Nov-Dec | Nutrition | pmid:10575679 |
| Jeevanandam M and Petersen SR | Substrate fuel kinetics in enterally fed trauma patients supplemented with ornithine alpha ketoglutarate. | 1999 | Clin Nutr | pmid:10578020 |
| Lundquist JT and Dix TA | Synthesis and human neurotensin receptor binding activities of neurotensin(8-13) analogues containing position 8 alpha-azido-N-alkylated derivatives of ornithine, lysine, and homolysine. | 1999 | J. Med. Chem. | pmid:10579853 |
| Heinänen K et al. | Creatine corrects muscle 31P spectrum in gyrate atrophy with hyperornithinaemia. | 1999 | Eur. J. Clin. Invest. | pmid:10583455 |
| Peterson LJ and Reynolds D | The effectiveness of a synthetic vasopressin analogue as a vasoconstrictor. | 1975 | Pharmacol Ther Dent | pmid:1058502 |
| Renau TE et al. | Inhibitors of efflux pumps in Pseudomonas aeruginosa potentiate the activity of the fluoroquinolone antibacterial levofloxacin. | 1999 | J. Med. Chem. | pmid:10585202 |
| Robinson LE et al. | Amino acid nutrition and immune function in tumour-bearing rats: a comparison of glutamine-, arginine- and ornithine 2-oxoglutarate-supplemented diets. | 1999 | Clin. Sci. | pmid:10585893 |
| Donati L et al. | Nutritional and clinical efficacy of ornithine alpha-ketoglutarate in severe burn patients. | 1999 | Clin Nutr | pmid:10601539 |
| Werneck-Barroso E et al. | Nitric oxide production by BCG-infected pleural macrophages from C57Bl/6 and DBA-2 mice. | 2000 | Int. J. Mol. Med. | pmid:10601581 |
| Sass JO and Skladal D | Plasma concentrations and renal clearance of orotic acid in argininosuccinic acid synthetase deficiency. | 1999 | Pediatr. Nephrol. | pmid:10603147 |
| Valtonen M et al. | Central nervous system involvement in gyrate atrophy of the choroid and retina with hyperornithinaemia. | 1999 | J. Inherit. Metab. Dis. | pmid:10604138 |
| Antoine FR et al. | HPLC method for analysis of free amino acids in fish using o-phthaldialdehyde precolumn derivatization. | 1999 | J. Agric. Food Chem. | pmid:10606579 |
| Napper GA and Kalloniatis M | Neurochemical changes following postmortem ischemia in the rat retina. | 1999 Nov-Dec | Vis. Neurosci. | pmid:10614596 |
| Mashima YG et al. | Genotype-phenotype correlation of a pyridoxine-responsive form of gyrate atrophy. | 1999 | Ophthalmic Genet. | pmid:10617919 |
| Ajmani PS et al. | Enhanced transgene expression in rat brain cell cultures with a disulfide-containing cationic lipid. | 1999 | Neurosci. Lett. | pmid:10626833 |
| Polticelli F et al. | Structural determinants of trypsin affinity and specificity for cationic inhibitors. | 1999 | Protein Sci. | pmid:10631977 |
| Mamont PS et al. | Alpha-methyl ornithine, a potent competitive inhibitor of ornithine decarboxylase, blocks proliferation of rat hepatoma cells in culture. | 1976 | Proc. Natl. Acad. Sci. U.S.A. | pmid:1064034 |
| Lin LI | Total deviation index for measuring individual agreement with applications in laboratory performance and bioequivalence. | 2000 | Stat Med | pmid:10641028 |
| Ando A et al. | Heterogeneity in ornithine cytotoxicity of bovine retinal pigment epithelial cells in primary culture. | 2000 | Exp. Eye Res. | pmid:10644424 |
| Quintero MJ et al. | Arginine catabolism in the cyanobacterium Synechocystis sp. Strain PCC 6803 involves the urea cycle and arginase pathway. | 2000 | J. Bacteriol. | pmid:10648527 |
| Kasson PM et al. | Kinetics of peptide binding to the class II MHC protein I-Ek. | 2000 | Biochemistry | pmid:10653650 |
| Wang T et al. | Correction of ornithine accumulation prevents retinal degeneration in a mouse model of gyrate atrophy of the choroid and retina. | 2000 | Proc. Natl. Acad. Sci. U.S.A. | pmid:10655512 |
| Ascenzi P et al. | Serine proteinase inhibition by the active site titrant N alpha-(N, N-dimethylcarbamoyl)-alpha-azaornithine p-nitrophenyl ester. A comparative study. | 2000 | Eur. J. Biochem. | pmid:10672036 |
| Lindorf HH | [Hemostasis and reactive hypermia in POR-8 and adrenaline infiltration]. | 1976 | Fortschr Kiefer Gesichtschir | pmid:1068104 |
| Ródenas J et al. | Different roles for nitrogen monoxide and peroxynitrite in lipid peroxidation induced by activated neutrophils. | 2000 | Free Radic. Biol. Med. | pmid:10699748 |
| Bergström J et al. | Influence of severe potassium depletion and subsequent repletion with potassium on muscle electrolytes, metabolites and amino acids in man. | 1976 | Clin Sci Mol Med | pmid:1070423 |
| McDuffie JE et al. | 5-hydroxytryptamine stimulates phosphorylation of p44/p42 mitogen-activated protein kinase activation in bovine aortic endothelial cell cultures. | 2000 | J. Cardiovasc. Pharmacol. | pmid:10710124 |
| O'Sullivan D et al. | Catabolism of arginine and ornithine in the perfused rat liver: effect of dietary protein and of glucagon. | 2000 | Am. J. Physiol. Endocrinol. Metab. | pmid:10710507 |
| Chen HP et al. | Purification and properties of ornithine racemase from Clostridium sticklandii. | 2000 | J. Bacteriol. | pmid:10715017 |
| Arena ME et al. | Arginine, citrulline and ornithine metabolism by lactic acid bacteria from wine. | 1999 | Int. J. Food Microbiol. | pmid:10733246 |
| Süer Gökmen S et al. | Arginase and ornithine, as markers in human non-small cell lung carcinoma. | 1999 | Cancer Biochem. Biophys. | pmid:10738908 |
| Rosowsky A et al. | The effect of side-chain, para-aminobenzoyl region, and B-ring modifications on dihydrofolate reductase binding, influx via the reduced folate carrier, and cytotoxicity of the potent nonpolyglutamatable antifolate N(alpha)-(4-amino-4-deoxypteroyl)-N(delta)-hemiphthaloyl-L- ornithine. | 2000 | Pharmacol. Ther. | pmid:10739874 |