Lipoic acid

Lipoic acid is a lipid of Fatty Acyls (FA) class.

Cross Reference

There are no associated biomedical information in the current reference collection.

Current reference collection contains 18962 references associated with Lipoic acid in LipidPedia. Due to lack of full text of references or no associated biomedical terms are recognized in our current text-mining method, we cannot extract any biomedical terms related to diseases, pathways, locations, functions, genes, lipids, and animal models from the associated reference collection.

Users can download the reference list at the bottom of this page and read the reference manually to find out biomedical information.


Here are additional resources we collected from PubChem and MeSH for Lipoic acid

Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Lipoic acid

MeSH term MeSH ID Detail
Ochronosis D009794 1 associated lipids
Sick Building Syndrome D018877 1 associated lipids
Photophobia D020795 1 associated lipids
Heavy Metal Poisoning, Nervous System D020260 1 associated lipids
Laryngopharyngeal Reflux D057045 1 associated lipids
Binge Drinking D063425 1 associated lipids
Taste Disorders D013651 1 associated lipids
Lead Poisoning, Nervous System D020263 1 associated lipids
Dysgeusia D004408 1 associated lipids
Alkaptonuria D000474 1 associated lipids
Per page 10 20 50 100 | Total 177

PubChem Biomolecular Interactions and Pathways

NCBI Entrez Crosslinks

All references with Lipoic acid

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Per page 10 20 50 100 | Total 4476
Authors Title Published Journal PubMed Link
Vacchina P et al. Lipoic acid metabolism in Trypanosoma cruzi as putative target for chemotherapy. 2018 Exp. Parasitol. pmid:29409741
Fayyaz MH et al. Survival of buffalo bull spermatozoa: effect on structure and function due to alpha-lipoic acid and cholesterol-loaded cyclodextrin. 2017 Andrologia pmid:27491811
El-Sayed EM et al. Alpha lipoic acid prevents doxorubicin-induced nephrotoxicity by mitigation of oxidative stress, inflammation, and apoptosis in rats. 2017 J. Biochem. Mol. Toxicol. pmid:28598563
How SC et al. Cell-targeted, dual reduction- and pH-responsive saccharide/lipoic acid-modified poly(L-lysine) and poly(acrylic acid) polyionic complex nanogels for drug delivery. 2017 Colloids Surf B Biointerfaces pmid:28267669
Bernardinelli E et al. Mis-targeting of the mitochondrial protein LIPT2 leads to apoptotic cell death. 2017 PLoS ONE pmid:28628643
Cichoń M et al. [Effect of α-lipoic acid on free radical processes in serum of rats on high fat diet]. 2017 Med Pr pmid:28512366
Al-Ghamdi MA et al. POTENTIAL ADMINISTRATION OF LIPOIC ACID AND COENZYME Q AGAINST ADIPOGENSIS: TARGET FOR WEIGHT REDUCTION. 2017 Afr J Tradit Complement Altern Med pmid:28480405
Bilska-Wilkosz A et al. Lipoic Acid as a Possible Pharmacological Source of Hydrogen Sulfide/Sulfane Sulfur. 2017 Molecules pmid:28257119
Luchetti R et al. Observational multicentric survey on carpal tunnel syndrome: demographic and clinical data from 34 Italian centers. 2017 Eur Rev Med Pharmacol Sci pmid:28239826
Zee T et al. α-Lipoic acid treatment prevents cystine urolithiasis in a mouse model of cystinuria. 2017 Nat. Med. pmid:28165480
Zhang T et al. Tang-Luo-Ning Improves Mitochondrial Antioxidase Activity in Dorsal Root Ganglia of Diabetic Rats: A Proteomics Study. 2017 Biomed Res Int pmid:28133612
Takeda T et al. α-Lipoic acid potentially targets AMP-activated protein kinase and energy production in the fetal brain to ameliorate dioxin-produced attenuation in fetal steroidogenesis. 2017 J Toxicol Sci pmid:28070105
Sun Y et al. Overproduction of α-Lipoic Acid by Gene Manipulated Escherichia coli. 2017 PLoS ONE pmid:28068366
Kangawa Y et al. Anti-inflammatory effects of the selective phosphodiesterase 3 inhibitor, cilostazol, and antioxidants, enzymatically-modified isoquercitrin and α-lipoic acid, reduce dextran sulphate sodium-induced colorectal mucosal injury in mice. 2017 Exp. Toxicol. Pathol. pmid:28089463
Polanski JF et al. Antioxidant therapy in the elderly with tinnitus. 2016 May-Jun Braz J Otorhinolaryngol pmid:26547700
Salvi A et al. Effect of Hydrogen Sulfide Donors on Intraocular Pressure in Rabbits. 2016 Jul-Aug J Ocul Pharmacol Ther pmid:27092593
Alpay M et al. Antileukemic effects of piperlongumine and alpha lipoic acid combination on Jurkat, MEC1 and NB4 cells in vitro. 2016 Apr-Jun J Cancer Res Ther pmid:27461609
Choi JH et al. α-Lipoic Acid Inhibits Expression of IL-8 by Suppressing Activation of MAPK, Jak/Stat, and NF-κB in H. pylori-Infected Gastric Epithelial AGS Cells. 2016 Yonsei Med. J. pmid:26632410
Madias JE A-lipoic acid therapy mediated amelioration of sympathetic heart denervation in patients with takotsubo syndrome. 2016 J Cardiol pmid:26603324
Ali SO et al. Curcumin, Silybin Phytosome(®) and α-R-Lipoic Acid Mitigate Chronic Hepatitis in Rat by Inhibiting Oxidative Stress and Inflammatory Cytokines Production. 2016 Basic Clin. Pharmacol. Toxicol. pmid:26457982
Liang S et al. Role of Cyt-C/caspases-9,3, Bax/Bcl-2 and the FAS death receptor pathway in apoptosis induced by zinc oxide nanoparticles in human aortic endothelial cells and the protective effect by alpha-lipoic acid. 2016 Chem. Biol. Interact. pmid:27544635
Marfella R et al. Effects of α-lipoic acid therapy on sympathetic heart innervation in patients with previous experience of transient takotsubo cardiomyopathy. 2016 J Cardiol pmid:26347218
Hiller S et al. Alpha-lipoic acid supplementation protects enzymes from damage by nitrosative and oxidative stress. 2016 Biochim. Biophys. Acta pmid:26344063
Fiore E et al. Effect of combined acetylmethionine, cyanocobalamin and α-lipoic acid on hepatic metabolism in high-yielding dairy cow. 2016 J. Dairy Res. pmid:27845016
Rideout TC et al. Complementary Cholesterol-Lowering Response of a Phytosterol/α-Lipoic Acid Combination in Obese Zucker Rats. 2016 J Diet Suppl pmid:25664679
Hu C et al. Synergistic effect of reduced polypeptide micelle for co-delivery of doxorubicin and TRAIL against drug-resistance in breast cancer. 2016 Oncotarget pmid:27557520
Becucci L et al. Channel-forming activity of syringopeptin 25A in mercury-supported lipid bilayers with a phosphatidylcholine distal leaflet. 2016 Bioelectrochemistry pmid:26680109
Aydın A and Yıldırım AM Effects of alpha lipoic acid on ischemia-reperfusion injury in rat hindlimb ischemia model. 2016 Ulus Travma Acil Cerrahi Derg pmid:28074465
Roberts JD et al. An Exploratory Investigation of Endotoxin Levels in Novice Long Distance Triathletes, and the Effects of a Multi-Strain Probiotic/Prebiotic, Antioxidant Intervention. 2016 Nutrients pmid:27869661
Tao Y et al. α-Lipoic Acid Treatment Improves Vision-Related Quality of Life in Patients with Dry Age-Related Macular Degeneration. 2016 Tohoku J. Exp. Med. pmid:27840374
Derosa G et al. A Clinical Trial about a Food Supplement Containing α-Lipoic Acid on Oxidative Stress Markers in Type 2 Diabetic Patients. 2016 Int J Mol Sci pmid:27801825
Zhang J and McCullough PA Lipoic Acid in the Prevention of Acute Kidney Injury. 2016 Nephron pmid:27603173
Arikan M et al. Histomorphometric and Ultrastructural Evaluation of Long-Term Alpha Lipoic Acid and Vitamin B12 Use After Experimental Sciatic Nerve Injury in Rats. 2016 Turk Neurosurg pmid:27476916
Niska K et al. Capping Agent-Dependent Toxicity and Antimicrobial Activity of Silver Nanoparticles: An In Vitro Study. Concerns about Potential Application in Dental Practice. 2016 Int J Med Sci pmid:27766027
Zhang L et al. Study on the clinical value of alprostadil combined with α-lipoic acid in treatment of type 2 diabetes mellitus patients with erectile dysfunction. 2016 Eur Rev Med Pharmacol Sci pmid:27735021
Zorzoli A et al. Staphylococcus aureus Tissue Infection During Sepsis Is Supported by Differential Use of Bacterial or Host-Derived Lipoic Acid. 2016 PLoS Pathog. pmid:27701474
Gao S et al. Oxidative stress increases the risk of pancreatic β cell damage in chronic renal hypertensive rats. 2016 Physiol Rep pmid:27535482
Güleş Ö and Eren Ü Protective role of alpha lipoic acid against polychlorobiphenyl (Aroclor 1254)-induced testicular toxicity in rats. 2016 Rom J Morphol Embryol pmid:27516018
Wang Y et al. Protective Effect of ALA in Crushed Optic Nerve Cat Retinal Ganglion Cells Using a New Marker RBPMS. 2016 PLoS ONE pmid:27504635
Cacciatore I et al. Novel NSAID-Derived Drugs for the Potential Treatment of Alzheimer's Disease. 2016 Int J Mol Sci pmid:27376271
Ikuta N et al. Bioavailability of an R-α-Lipoic Acid/γ-Cyclodextrin Complex in Healthy Volunteers. 2016 Int J Mol Sci pmid:27314343
Li D et al. The Protective Effects of 5-Methoxytryptamine-α-lipoic Acid on Ionizing Radiation-Induced Hematopoietic Injury. 2016 Int J Mol Sci pmid:27314327
Santos V and Hirshfield I The Physiological and Molecular Characterization of a Small Colony Variant of Escherichia coli and Its Phenotypic Rescue. 2016 PLoS ONE pmid:27310825
Bartkoski S and Day M Alpha-Lipoic Acid for Treatment of Diabetic Peripheral Neuropathy. 2016 Am Fam Physician pmid:27175957
Costantino M et al. Resolution of subchorionic hematoma and symptoms of threatened miscarriage using vaginal alpha lipoic acid or progesterone: clinical evidences. 2016 Eur Rev Med Pharmacol Sci pmid:27160142
Cronan JE Assembly of Lipoic Acid on Its Cognate Enzymes: an Extraordinary and Essential Biosynthetic Pathway. 2016 Microbiol. Mol. Biol. Rev. pmid:27074917
Ying Z et al. Lipoicmethylenedioxyphenol Reduces Experimental Atherosclerosis through Activation of Nrf2 Signaling. 2016 PLoS ONE pmid:26859892
Moon HS Chemopreventive Effects of Alpha Lipoic Acid on Obesity-Related Cancers. 2016 Ann. Nutr. Metab. pmid:26829711
Uchida R et al. Investigation of Enantioselective Membrane Permeability of α-Lipoic Acid in Caco-2 and MDCKII Cell. 2016 Int J Mol Sci pmid:26821014
Abdelkarem HM et al. Alleviation of bone markers in rats induced nano-zinc oxide by qurecetin and α-lipolic acid. 2016 Toxicol. Mech. Methods pmid:27785948