| MeSH term | MeSH ID | Detail |
|---|---|---|
| Hemolysis | D006461 | 131 associated lipids |
| Stomach Ulcer | D013276 | 75 associated lipids |
| Kidney Failure, Chronic | D007676 | 51 associated lipids |
| Diabetes Mellitus | D003920 | 90 associated lipids |
| Lead Poisoning | D007855 | 4 associated lipids |
| Hearing Loss, Sensorineural | D006319 | 8 associated lipids |
| Hypoxia | D000860 | 23 associated lipids |
| Arrhythmias, Cardiac | D001145 | 42 associated lipids |
| Acidosis, Lactic | D000140 | 8 associated lipids |
| Lung Neoplasms | D008175 | 171 associated lipids |
Lipoic acid
Lipoic acid is a lipid of Fatty Acyls (FA) class.
Cross Reference
There are no associated biomedical information in the current reference collection.
Current reference collection contains 18962 references associated with Lipoic acid in LipidPedia. Due to lack of full text of references or no associated biomedical terms are recognized in our current text-mining method, we cannot extract any biomedical terms related to diseases, pathways, locations, functions, genes, lipids, and animal models from the associated reference collection.
Users can download the reference list at the bottom of this page and read the reference manually to find out biomedical information.
Here are additional resources we collected from PubChem and MeSH for Lipoic acid
Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with Lipoic acid
PubChem Biomolecular Interactions and Pathways
NCBI Entrez Crosslinks
All references with Lipoic acid
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Vacchina P et al. | Lipoic acid metabolism in Trypanosoma cruzi as putative target for chemotherapy. | 2018 | Exp. Parasitol. | pmid:29409741 |
| Fayyaz MH et al. | Survival of buffalo bull spermatozoa: effect on structure and function due to alpha-lipoic acid and cholesterol-loaded cyclodextrin. | 2017 | Andrologia | pmid:27491811 |
| El-Sayed EM et al. | Alpha lipoic acid prevents doxorubicin-induced nephrotoxicity by mitigation of oxidative stress, inflammation, and apoptosis in rats. | 2017 | J. Biochem. Mol. Toxicol. | pmid:28598563 |
| How SC et al. | Cell-targeted, dual reduction- and pH-responsive saccharide/lipoic acid-modified poly(L-lysine) and poly(acrylic acid) polyionic complex nanogels for drug delivery. | 2017 | Colloids Surf B Biointerfaces | pmid:28267669 |
| Bernardinelli E et al. | Mis-targeting of the mitochondrial protein LIPT2 leads to apoptotic cell death. | 2017 | PLoS ONE | pmid:28628643 |
| Cichoń M et al. | [Effect of α-lipoic acid on free radical processes in serum of rats on high fat diet]. | 2017 | Med Pr | pmid:28512366 |
| Al-Ghamdi MA et al. | POTENTIAL ADMINISTRATION OF LIPOIC ACID AND COENZYME Q AGAINST ADIPOGENSIS: TARGET FOR WEIGHT REDUCTION. | 2017 | Afr J Tradit Complement Altern Med | pmid:28480405 |
| Bilska-Wilkosz A et al. | Lipoic Acid as a Possible Pharmacological Source of Hydrogen Sulfide/Sulfane Sulfur. | 2017 | Molecules | pmid:28257119 |
| Luchetti R et al. | Observational multicentric survey on carpal tunnel syndrome: demographic and clinical data from 34 Italian centers. | 2017 | Eur Rev Med Pharmacol Sci | pmid:28239826 |
| Zee T et al. | α-Lipoic acid treatment prevents cystine urolithiasis in a mouse model of cystinuria. | 2017 | Nat. Med. | pmid:28165480 |
| Zhang T et al. | Tang-Luo-Ning Improves Mitochondrial Antioxidase Activity in Dorsal Root Ganglia of Diabetic Rats: A Proteomics Study. | 2017 | Biomed Res Int | pmid:28133612 |
| Takeda T et al. | α-Lipoic acid potentially targets AMP-activated protein kinase and energy production in the fetal brain to ameliorate dioxin-produced attenuation in fetal steroidogenesis. | 2017 | J Toxicol Sci | pmid:28070105 |
| Sun Y et al. | Overproduction of α-Lipoic Acid by Gene Manipulated Escherichia coli. | 2017 | PLoS ONE | pmid:28068366 |
| Kangawa Y et al. | Anti-inflammatory effects of the selective phosphodiesterase 3 inhibitor, cilostazol, and antioxidants, enzymatically-modified isoquercitrin and α-lipoic acid, reduce dextran sulphate sodium-induced colorectal mucosal injury in mice. | 2017 | Exp. Toxicol. Pathol. | pmid:28089463 |
| Polanski JF et al. | Antioxidant therapy in the elderly with tinnitus. | 2016 May-Jun | Braz J Otorhinolaryngol | pmid:26547700 |
| Salvi A et al. | Effect of Hydrogen Sulfide Donors on Intraocular Pressure in Rabbits. | 2016 Jul-Aug | J Ocul Pharmacol Ther | pmid:27092593 |
| Alpay M et al. | Antileukemic effects of piperlongumine and alpha lipoic acid combination on Jurkat, MEC1 and NB4 cells in vitro. | 2016 Apr-Jun | J Cancer Res Ther | pmid:27461609 |
| Rousseau AS et al. | α-Lipoic acid up-regulates expression of peroxisome proliferator-activated receptor β in skeletal muscle: involvement of the JNK signaling pathway. | 2016 | FASEB J. | pmid:26655383 |
| Choi JH et al. | α-Lipoic Acid Inhibits Expression of IL-8 by Suppressing Activation of MAPK, Jak/Stat, and NF-κB in H. pylori-Infected Gastric Epithelial AGS Cells. | 2016 | Yonsei Med. J. | pmid:26632410 |
| Madias JE | A-lipoic acid therapy mediated amelioration of sympathetic heart denervation in patients with takotsubo syndrome. | 2016 | J Cardiol | pmid:26603324 |
| Ali SO et al. | Curcumin, Silybin Phytosome(®) and α-R-Lipoic Acid Mitigate Chronic Hepatitis in Rat by Inhibiting Oxidative Stress and Inflammatory Cytokines Production. | 2016 | Basic Clin. Pharmacol. Toxicol. | pmid:26457982 |
| Liang S et al. | Role of Cyt-C/caspases-9,3, Bax/Bcl-2 and the FAS death receptor pathway in apoptosis induced by zinc oxide nanoparticles in human aortic endothelial cells and the protective effect by alpha-lipoic acid. | 2016 | Chem. Biol. Interact. | pmid:27544635 |
| Marfella R et al. | Effects of α-lipoic acid therapy on sympathetic heart innervation in patients with previous experience of transient takotsubo cardiomyopathy. | 2016 | J Cardiol | pmid:26347218 |
| Hiller S et al. | Alpha-lipoic acid supplementation protects enzymes from damage by nitrosative and oxidative stress. | 2016 | Biochim. Biophys. Acta | pmid:26344063 |
| Cheserek MJ et al. | Cardioprotective effects of lipoic acid, quercetin and resveratrol on oxidative stress related to thyroid hormone alterations in long-term obesity. | 2016 | J. Nutr. Biochem. | pmid:27260466 |
| Fiore E et al. | Effect of combined acetylmethionine, cyanocobalamin and α-lipoic acid on hepatic metabolism in high-yielding dairy cow. | 2016 | J. Dairy Res. | pmid:27845016 |
| Rideout TC et al. | Complementary Cholesterol-Lowering Response of a Phytosterol/α-Lipoic Acid Combination in Obese Zucker Rats. | 2016 | J Diet Suppl | pmid:25664679 |
| Zieleniecki JL et al. | Cell-Free Synthesis of a Functional Membrane Transporter into a Tethered Bilayer Lipid Membrane. | 2016 | Langmuir | pmid:26910192 |
| Harless L and Liang J | Pharmacologic treatment for postviral olfactory dysfunction: a systematic review. | 2016 | Int Forum Allergy Rhinol | pmid:26879592 |
| Hu C et al. | Synergistic effect of reduced polypeptide micelle for co-delivery of doxorubicin and TRAIL against drug-resistance in breast cancer. | 2016 | Oncotarget | pmid:27557520 |
| Becucci L et al. | Channel-forming activity of syringopeptin 25A in mercury-supported lipid bilayers with a phosphatidylcholine distal leaflet. | 2016 | Bioelectrochemistry | pmid:26680109 |
| Aydın A and Yıldırım AM | Effects of alpha lipoic acid on ischemia-reperfusion injury in rat hindlimb ischemia model. | 2016 | Ulus Travma Acil Cerrahi Derg | pmid:28074465 |
| Al-Matubsi HY et al. | Effects of Lipoic Acid Supplementation on Activities of Cyclooxygenases and Levels of Prostaglandins E2 and F2α Metabolites, in the Offspring of Rats with Streptozotocin-Induced Diabetes. | 2016 | J Diabetes Res | pmid:28042582 |
| Moura FA et al. | Colonic and Hepatic Modulation by Lipoic Acid and/or N-Acetylcysteine Supplementation in Mild Ulcerative Colitis Induced by Dextran Sodium Sulfate in Rats. | 2016 | Oxid Med Cell Longev | pmid:27957238 |
| Williams CA | The effect of oxidative stress during exercise in the horse. | 2016 | J. Anim. Sci. | pmid:27898872 |
| Li Y and Monteiro-Riviere NA | Mechanisms of cell uptake, inflammatory potential and protein corona effects with gold nanoparticles. | 2016 | Nanomedicine (Lond) | pmid:27882809 |
| Roberts JD et al. | An Exploratory Investigation of Endotoxin Levels in Novice Long Distance Triathletes, and the Effects of a Multi-Strain Probiotic/Prebiotic, Antioxidant Intervention. | 2016 | Nutrients | pmid:27869661 |
| Tao Y et al. | α-Lipoic Acid Treatment Improves Vision-Related Quality of Life in Patients with Dry Age-Related Macular Degeneration. | 2016 | Tohoku J. Exp. Med. | pmid:27840374 |
| Derosa G et al. | A Clinical Trial about a Food Supplement Containing α-Lipoic Acid on Oxidative Stress Markers in Type 2 Diabetic Patients. | 2016 | Int J Mol Sci | pmid:27801825 |
| Zhang J and McCullough PA | Lipoic Acid in the Prevention of Acute Kidney Injury. | 2016 | Nephron | pmid:27603173 |
| Arikan M et al. | Histomorphometric and Ultrastructural Evaluation of Long-Term Alpha Lipoic Acid and Vitamin B12 Use After Experimental Sciatic Nerve Injury in Rats. | 2016 | Turk Neurosurg | pmid:27476916 |
| Niska K et al. | Capping Agent-Dependent Toxicity and Antimicrobial Activity of Silver Nanoparticles: An In Vitro Study. Concerns about Potential Application in Dental Practice. | 2016 | Int J Med Sci | pmid:27766027 |
| Zhang L et al. | Study on the clinical value of alprostadil combined with α-lipoic acid in treatment of type 2 diabetes mellitus patients with erectile dysfunction. | 2016 | Eur Rev Med Pharmacol Sci | pmid:27735021 |
| Zorzoli A et al. | Staphylococcus aureus Tissue Infection During Sepsis Is Supported by Differential Use of Bacterial or Host-Derived Lipoic Acid. | 2016 | PLoS Pathog. | pmid:27701474 |
| Gao S et al. | Oxidative stress increases the risk of pancreatic β cell damage in chronic renal hypertensive rats. | 2016 | Physiol Rep | pmid:27535482 |
| Güleş Ö and Eren Ü | Protective role of alpha lipoic acid against polychlorobiphenyl (Aroclor 1254)-induced testicular toxicity in rats. | 2016 | Rom J Morphol Embryol | pmid:27516018 |
| Wang Y et al. | Protective Effect of ALA in Crushed Optic Nerve Cat Retinal Ganglion Cells Using a New Marker RBPMS. | 2016 | PLoS ONE | pmid:27504635 |
| Cacciatore I et al. | Novel NSAID-Derived Drugs for the Potential Treatment of Alzheimer's Disease. | 2016 | Int J Mol Sci | pmid:27376271 |
| Ikuta N et al. | Bioavailability of an R-α-Lipoic Acid/γ-Cyclodextrin Complex in Healthy Volunteers. | 2016 | Int J Mol Sci | pmid:27314343 |
| Li D et al. | The Protective Effects of 5-Methoxytryptamine-α-lipoic Acid on Ionizing Radiation-Induced Hematopoietic Injury. | 2016 | Int J Mol Sci | pmid:27314327 |
| Santos V and Hirshfield I | The Physiological and Molecular Characterization of a Small Colony Variant of Escherichia coli and Its Phenotypic Rescue. | 2016 | PLoS ONE | pmid:27310825 |
| Bartkoski S and Day M | Alpha-Lipoic Acid for Treatment of Diabetic Peripheral Neuropathy. | 2016 | Am Fam Physician | pmid:27175957 |
| Costantino M et al. | Resolution of subchorionic hematoma and symptoms of threatened miscarriage using vaginal alpha lipoic acid or progesterone: clinical evidences. | 2016 | Eur Rev Med Pharmacol Sci | pmid:27160142 |
| Cronan JE | Assembly of Lipoic Acid on Its Cognate Enzymes: an Extraordinary and Essential Biosynthetic Pathway. | 2016 | Microbiol. Mol. Biol. Rev. | pmid:27074917 |
| Ying Z et al. | Lipoicmethylenedioxyphenol Reduces Experimental Atherosclerosis through Activation of Nrf2 Signaling. | 2016 | PLoS ONE | pmid:26859892 |
| Moon HS | Chemopreventive Effects of Alpha Lipoic Acid on Obesity-Related Cancers. | 2016 | Ann. Nutr. Metab. | pmid:26829711 |
| Uchida R et al. | Investigation of Enantioselective Membrane Permeability of α-Lipoic Acid in Caco-2 and MDCKII Cell. | 2016 | Int J Mol Sci | pmid:26821014 |
| Abdelkarem HM et al. | Alleviation of bone markers in rats induced nano-zinc oxide by qurecetin and α-lipolic acid. | 2016 | Toxicol. Mech. Methods | pmid:27785948 |
| Gurcay AG et al. | Comparative Biochemical and Motor Function Analysis of Alpha Lipoic Acid and N-Acetyl Cysteine Treatment on Rats with Experimental Spinal Cord Injury. | 2016 | Turk Neurosurg | pmid:26768878 |
| Hwang S et al. | Inhibitory Effects of α-Lipoic Acid on Oxidative Stress-Induced Adipogenesis in Orbital Fibroblasts From Patients With Graves Ophthalmopathy. | 2016 | Medicine (Baltimore) | pmid:26765462 |
| Wang J et al. | Xenobiotics and loss of tolerance in primary biliary cholangitis. | 2016 | World J. Gastroenterol. | pmid:26755880 |
| Ströher E et al. | Glutaredoxin S15 Is Involved in Fe-S Cluster Transfer in Mitochondria Influencing Lipoic Acid-Dependent Enzymes, Plant Growth, and Arsenic Tolerance in Arabidopsis. | 2016 | Plant Physiol. | pmid:26672074 |
| Sun B et al. | Robust, active tumor-targeting and fast bioresponsive anticancer nanotherapeutics based on natural endogenous materials. | 2016 | Acta Biomater | pmid:27576338 |
| Bilska-Wilkosz A et al. | The effect of lipoic acid administration on the urinary excretion of thiocyanate in rats exposed to potassium cyanide. | 2015 Jan-Feb | Acta Pol Pharm | pmid:25850200 |
| Zalejska-Fiolka J et al. | The Influence of α-Lipoic Acid and Garlic Administration on Biomarkers of Oxidative Stress and Inflammation in Rabbits Exposed to Oxidized Nutrition Oils. | 2015 | Biomed Res Int | pmid:26634212 |
| Chaudhary P et al. | Lipoic acid reduces inflammation in a mouse focal cortical experimental autoimmune encephalomyelitis model. | 2015 | J. Neuroimmunol. | pmid:26616873 |
| Nebbioso M et al. | Biomolecular Modulation of Neurodegenerative Events during Ageing. | 2015 | Oxid Med Cell Longev | pmid:26583065 |
| Ke C et al. | Plasma Metabolic Profiles in Women are Menopause Dependent. | 2015 | PLoS ONE | pmid:26580805 |
| Alla AJ et al. | Selective capture of glycoproteins using lectin-modified nanoporous gold monolith. | 2015 | J Chromatogr A | pmid:26554297 |
| Xing ZG et al. | Effects and mechanism of lipoic acid on beta-amyloid-intoxicated C6 glioma cells. | 2015 | Genet. Mol. Res. | pmid:26535703 |
| Favero G et al. | A comparison of melatonin and α-lipoic acid in the induction of antioxidant defences in L6 rat skeletal muscle cells. | 2015 | Age (Dordr) | pmid:26250907 |
| El Batsh MM et al. | Protective effects of alpha-lipoic acid against benzene induced toxicity in experimental rats. | 2015 | Eur Rev Med Pharmacol Sci | pmid:26221905 |
| Scaramuzza A et al. | Alpha-Lipoic Acid and Antioxidant Diet Help to Improve Endothelial Dysfunction in Adolescents with Type 1 Diabetes: A Pilot Trial. | 2015 | J Diabetes Res | pmid:26171398 |
| Zou H et al. | Alpha-lipoic acid protects against cadmium-induced hepatotoxicity via calcium signalling and gap junctional intercellular communication in rat hepatocytes. | 2015 | J Toxicol Sci | pmid:26165643 |
| Çakır T et al. | The effect of alpha lipoic acid on rat kidneys in methotrexate induced oxidative injury. | 2015 | Eur Rev Med Pharmacol Sci | pmid:26125279 |
| Kafara P et al. | Lipoic acid decreases Mcl-1, Bcl-xL and up regulates Bim on ovarian carcinoma cells leading to cell death. | 2015 | J Ovarian Res | pmid:26063499 |
| Santos CL et al. | Lipoic acid and N-acetylcysteine prevent ammonia-induced inflammatory response in C6 astroglial cells: The putative role of ERK and HO1 signaling pathways. | 2015 | Toxicol In Vitro | pmid:26043815 |
| Liu N et al. | Microwave-Assisted Resolution of α-Lipoic Acid Catalyzed by an Ionic Liquid Co-Lyophilized Lipase. | 2015 | Molecules | pmid:26035096 |
| Palacios-Sánchez B et al. | Alpha lipoic acid efficacy in burning mouth syndrome. A controlled clinical trial. | 2015 | Med Oral Patol Oral Cir Bucal | pmid:26034927 |
| Zhao L et al. | Lipoamide Acts as an Indirect Antioxidant by Simultaneously Stimulating Mitochondrial Biogenesis and Phase II Antioxidant Enzyme Systems in ARPE-19 Cells. | 2015 | PLoS ONE | pmid:26030919 |
| Tong X et al. | Activation of hepatic CREBH and Insig signaling in the anti-hypertriglyceridemic mechanism of R-α-lipoic acid. | 2015 | J. Nutr. Biochem. | pmid:26007286 |
| Zehnpfennig B et al. | Interaction of α-Lipoic Acid with the Human Na+/Multivitamin Transporter (hSMVT). | 2015 | J. Biol. Chem. | pmid:25971966 |
| Agostinis C et al. | The combination of N-acetyl cysteine, alpha-lipoic acid, and bromelain shows high anti-inflammatory properties in novel in vivo and in vitro models of endometriosis. | 2015 | Mediators Inflamm. | pmid:25960622 |
| Skibska B and Goraca A | The protective effect of lipoic acid on selected cardiovascular diseases caused by age-related oxidative stress. | 2015 | Oxid Med Cell Longev | pmid:25949771 |
| Uchida R et al. | Effect of γ-Cyclodextrin Inclusion Complex on the Absorption of R-α-Lipoic Acid in Rats. | 2015 | Int J Mol Sci | pmid:25946345 |
| Brandt YI et al. | Quantum dot assisted tracking of the intracellular protein Cyclin E in Xenopus laevis embryos. | 2015 | J Nanobiotechnology | pmid:25925383 |
| Çakır T et al. | Does alfa lipoic acid prevent liver from methotrexate induced oxidative injury in rats? | 2015 | Acta Cir Bras | pmid:25923257 |
| Hackert ML et al. | Lester Reed: A "complex" man who loved science. | 2015 | Proc. Natl. Acad. Sci. U.S.A. | pmid:25901319 |
| Huerta AE et al. | Effects of α-lipoic acid and eicosapentaenoic acid in overweight and obese women during weight loss. | 2015 | Obesity (Silver Spring) | pmid:25594166 |
| Berkowitz BA et al. | Oxidative stress and light-evoked responses of the posterior segment in a mouse model of diabetic retinopathy. | 2015 | Invest. Ophthalmol. Vis. Sci. | pmid:25574049 |
| Ying Z et al. | Alpha-lipoic acid activates eNOS through activation of PI3-kinase/Akt signaling pathway. | 2015 | Vascul. Pharmacol. | pmid:25460366 |
| Ergür BU et al. | The effects of α-lipoic acid on aortic injury and hypertension in the rat remnant kidney (5/6 nephrectomy) model. | 2015 | Anatol J Cardiol | pmid:25430409 |
| Dominguez JM et al. | Combination therapies prevent the neuropathic, proinflammatory characteristics of bone marrow in streptozotocin-induced diabetic rats. | 2015 | Diabetes | pmid:25204979 |
| Veskovic M et al. | Alpha-lipoic acid affects the oxidative stress in various brain structures in mice with methionine and choline deficiency. | 2015 | Exp. Biol. Med. (Maywood) | pmid:25193852 |
| Steliou K et al. | Bioprotective carnitinoids: lipoic acid, butyrate, and mitochondria-targeting to treat radiation injury: mitochondrial drugs come of age. | 2015 | Drug Dev. Res. | pmid:26109467 |
| Kan E et al. | Effects of two antioxidants; α-lipoic acid and fisetin against diabetic cataract in mice. | 2015 | Int Ophthalmol | pmid:25488016 |
| Mirza AZ | A novel drug delivery system of gold nanorods with doxorubicin and study of drug release by single molecule spectroscopy. | 2015 | J Drug Target | pmid:25148611 |
| Li BJ et al. | Effect of lipoic acid combined with paclitaxel on breast cancer cells. | 2015 | Genet. Mol. Res. | pmid:26782439 |
| Ma Q et al. | Molecular Mechanisms of Lipoic Acid Protection against Aflatoxin Bâ‚-Induced Liver Oxidative Damage and Inflammatory Responses in Broilers. | 2015 | Toxins (Basel) | pmid:26694462 |
| Wood SH et al. | Transcriptome analysis in calorie-restricted rats implicates epigenetic and post-translational mechanisms in neuroprotection and aging. | 2015 | Genome Biol. | pmid:26694192 |