Lipoic acid is a lipid of Fatty Acyls (FA) class.
We collected disease MeSH terms mapped to the references associated with Lipoic acid
Authors | Title | Published | Journal | PubMed Link |
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Vacchina P et al. | Lipoic acid metabolism in Trypanosoma cruzi as putative target for chemotherapy. | 2018 | Exp. Parasitol. | pmid:29409741 |
Fayyaz MH et al. | Survival of buffalo bull spermatozoa: effect on structure and function due to alpha-lipoic acid and cholesterol-loaded cyclodextrin. | 2017 | Andrologia | pmid:27491811 |
El-Sayed EM et al. | Alpha lipoic acid prevents doxorubicin-induced nephrotoxicity by mitigation of oxidative stress, inflammation, and apoptosis in rats. | 2017 | J. Biochem. Mol. Toxicol. | pmid:28598563 |
How SC et al. | Cell-targeted, dual reduction- and pH-responsive saccharide/lipoic acid-modified poly(L-lysine) and poly(acrylic acid) polyionic complex nanogels for drug delivery. | 2017 | Colloids Surf B Biointerfaces | pmid:28267669 |
Bernardinelli E et al. | Mis-targeting of the mitochondrial protein LIPT2 leads to apoptotic cell death. | 2017 | PLoS ONE | pmid:28628643 |
Cichoń M et al. | [Effect of α-lipoic acid on free radical processes in serum of rats on high fat diet]. | 2017 | Med Pr | pmid:28512366 |
Al-Ghamdi MA et al. | POTENTIAL ADMINISTRATION OF LIPOIC ACID AND COENZYME Q AGAINST ADIPOGENSIS: TARGET FOR WEIGHT REDUCTION. | 2017 | Afr J Tradit Complement Altern Med | pmid:28480405 |
Bilska-Wilkosz A et al. | Lipoic Acid as a Possible Pharmacological Source of Hydrogen Sulfide/Sulfane Sulfur. | 2017 | Molecules | pmid:28257119 |
Luchetti R et al. | Observational multicentric survey on carpal tunnel syndrome: demographic and clinical data from 34 Italian centers. | 2017 | Eur Rev Med Pharmacol Sci | pmid:28239826 |
Zee T et al. | α-Lipoic acid treatment prevents cystine urolithiasis in a mouse model of cystinuria. | 2017 | Nat. Med. | pmid:28165480 |
Zhang T et al. | Tang-Luo-Ning Improves Mitochondrial Antioxidase Activity in Dorsal Root Ganglia of Diabetic Rats: A Proteomics Study. | 2017 | Biomed Res Int | pmid:28133612 |
Takeda T et al. | α-Lipoic acid potentially targets AMP-activated protein kinase and energy production in the fetal brain to ameliorate dioxin-produced attenuation in fetal steroidogenesis. | 2017 | J Toxicol Sci | pmid:28070105 |
Sun Y et al. | Overproduction of α-Lipoic Acid by Gene Manipulated Escherichia coli. | 2017 | PLoS ONE | pmid:28068366 |
Kangawa Y et al. | Anti-inflammatory effects of the selective phosphodiesterase 3 inhibitor, cilostazol, and antioxidants, enzymatically-modified isoquercitrin and α-lipoic acid, reduce dextran sulphate sodium-induced colorectal mucosal injury in mice. | 2017 | Exp. Toxicol. Pathol. | pmid:28089463 |
Polanski JF et al. | Antioxidant therapy in the elderly with tinnitus. | 2016 May-Jun | Braz J Otorhinolaryngol | pmid:26547700 |
Salvi A et al. | Effect of Hydrogen Sulfide Donors on Intraocular Pressure in Rabbits. | 2016 Jul-Aug | J Ocul Pharmacol Ther | pmid:27092593 |
Alpay M et al. | Antileukemic effects of piperlongumine and alpha lipoic acid combination on Jurkat, MEC1 and NB4 cells in vitro. | 2016 Apr-Jun | J Cancer Res Ther | pmid:27461609 |
Rousseau AS et al. | α-Lipoic acid up-regulates expression of peroxisome proliferator-activated receptor β in skeletal muscle: involvement of the JNK signaling pathway. | 2016 | FASEB J. | pmid:26655383 |
Choi JH et al. | α-Lipoic Acid Inhibits Expression of IL-8 by Suppressing Activation of MAPK, Jak/Stat, and NF-κB in H. pylori-Infected Gastric Epithelial AGS Cells. | 2016 | Yonsei Med. J. | pmid:26632410 |
Madias JE | A-lipoic acid therapy mediated amelioration of sympathetic heart denervation in patients with takotsubo syndrome. | 2016 | J Cardiol | pmid:26603324 |
Ali SO et al. | Curcumin, Silybin Phytosome(®) and α-R-Lipoic Acid Mitigate Chronic Hepatitis in Rat by Inhibiting Oxidative Stress and Inflammatory Cytokines Production. | 2016 | Basic Clin. Pharmacol. Toxicol. | pmid:26457982 |
Liang S et al. | Role of Cyt-C/caspases-9,3, Bax/Bcl-2 and the FAS death receptor pathway in apoptosis induced by zinc oxide nanoparticles in human aortic endothelial cells and the protective effect by alpha-lipoic acid. | 2016 | Chem. Biol. Interact. | pmid:27544635 |
Marfella R et al. | Effects of α-lipoic acid therapy on sympathetic heart innervation in patients with previous experience of transient takotsubo cardiomyopathy. | 2016 | J Cardiol | pmid:26347218 |
Hiller S et al. | Alpha-lipoic acid supplementation protects enzymes from damage by nitrosative and oxidative stress. | 2016 | Biochim. Biophys. Acta | pmid:26344063 |
Cheserek MJ et al. | Cardioprotective effects of lipoic acid, quercetin and resveratrol on oxidative stress related to thyroid hormone alterations in long-term obesity. | 2016 | J. Nutr. Biochem. | pmid:27260466 |
Fiore E et al. | Effect of combined acetylmethionine, cyanocobalamin and α-lipoic acid on hepatic metabolism in high-yielding dairy cow. | 2016 | J. Dairy Res. | pmid:27845016 |
Rideout TC et al. | Complementary Cholesterol-Lowering Response of a Phytosterol/α-Lipoic Acid Combination in Obese Zucker Rats. | 2016 | J Diet Suppl | pmid:25664679 |
Zieleniecki JL et al. | Cell-Free Synthesis of a Functional Membrane Transporter into a Tethered Bilayer Lipid Membrane. | 2016 | Langmuir | pmid:26910192 |
Harless L and Liang J | Pharmacologic treatment for postviral olfactory dysfunction: a systematic review. | 2016 | Int Forum Allergy Rhinol | pmid:26879592 |
Hu C et al. | Synergistic effect of reduced polypeptide micelle for co-delivery of doxorubicin and TRAIL against drug-resistance in breast cancer. | 2016 | Oncotarget | pmid:27557520 |
Becucci L et al. | Channel-forming activity of syringopeptin 25A in mercury-supported lipid bilayers with a phosphatidylcholine distal leaflet. | 2016 | Bioelectrochemistry | pmid:26680109 |
Aydın A and Yıldırım AM | Effects of alpha lipoic acid on ischemia-reperfusion injury in rat hindlimb ischemia model. | 2016 | Ulus Travma Acil Cerrahi Derg | pmid:28074465 |
Al-Matubsi HY et al. | Effects of Lipoic Acid Supplementation on Activities of Cyclooxygenases and Levels of Prostaglandins E2 and F2α Metabolites, in the Offspring of Rats with Streptozotocin-Induced Diabetes. | 2016 | J Diabetes Res | pmid:28042582 |
Moura FA et al. | Colonic and Hepatic Modulation by Lipoic Acid and/or N-Acetylcysteine Supplementation in Mild Ulcerative Colitis Induced by Dextran Sodium Sulfate in Rats. | 2016 | Oxid Med Cell Longev | pmid:27957238 |
Williams CA | The effect of oxidative stress during exercise in the horse. | 2016 | J. Anim. Sci. | pmid:27898872 |
Li Y and Monteiro-Riviere NA | Mechanisms of cell uptake, inflammatory potential and protein corona effects with gold nanoparticles. | 2016 | Nanomedicine (Lond) | pmid:27882809 |
Roberts JD et al. | An Exploratory Investigation of Endotoxin Levels in Novice Long Distance Triathletes, and the Effects of a Multi-Strain Probiotic/Prebiotic, Antioxidant Intervention. | 2016 | Nutrients | pmid:27869661 |
Tao Y et al. | α-Lipoic Acid Treatment Improves Vision-Related Quality of Life in Patients with Dry Age-Related Macular Degeneration. | 2016 | Tohoku J. Exp. Med. | pmid:27840374 |
Derosa G et al. | A Clinical Trial about a Food Supplement Containing α-Lipoic Acid on Oxidative Stress Markers in Type 2 Diabetic Patients. | 2016 | Int J Mol Sci | pmid:27801825 |
Zhang J and McCullough PA | Lipoic Acid in the Prevention of Acute Kidney Injury. | 2016 | Nephron | pmid:27603173 |
Arikan M et al. | Histomorphometric and Ultrastructural Evaluation of Long-Term Alpha Lipoic Acid and Vitamin B12 Use After Experimental Sciatic Nerve Injury in Rats. | 2016 | Turk Neurosurg | pmid:27476916 |
Niska K et al. | Capping Agent-Dependent Toxicity and Antimicrobial Activity of Silver Nanoparticles: An In Vitro Study. Concerns about Potential Application in Dental Practice. | 2016 | Int J Med Sci | pmid:27766027 |
Zhang L et al. | Study on the clinical value of alprostadil combined with α-lipoic acid in treatment of type 2 diabetes mellitus patients with erectile dysfunction. | 2016 | Eur Rev Med Pharmacol Sci | pmid:27735021 |
Zorzoli A et al. | Staphylococcus aureus Tissue Infection During Sepsis Is Supported by Differential Use of Bacterial or Host-Derived Lipoic Acid. | 2016 | PLoS Pathog. | pmid:27701474 |
Gao S et al. | Oxidative stress increases the risk of pancreatic β cell damage in chronic renal hypertensive rats. | 2016 | Physiol Rep | pmid:27535482 |
Güleş Ö and Eren Ü | Protective role of alpha lipoic acid against polychlorobiphenyl (Aroclor 1254)-induced testicular toxicity in rats. | 2016 | Rom J Morphol Embryol | pmid:27516018 |
Wang Y et al. | Protective Effect of ALA in Crushed Optic Nerve Cat Retinal Ganglion Cells Using a New Marker RBPMS. | 2016 | PLoS ONE | pmid:27504635 |
Cacciatore I et al. | Novel NSAID-Derived Drugs for the Potential Treatment of Alzheimer's Disease. | 2016 | Int J Mol Sci | pmid:27376271 |
Ikuta N et al. | Bioavailability of an R-α-Lipoic Acid/γ-Cyclodextrin Complex in Healthy Volunteers. | 2016 | Int J Mol Sci | pmid:27314343 |
Li D et al. | The Protective Effects of 5-Methoxytryptamine-α-lipoic Acid on Ionizing Radiation-Induced Hematopoietic Injury. | 2016 | Int J Mol Sci | pmid:27314327 |
Santos V and Hirshfield I | The Physiological and Molecular Characterization of a Small Colony Variant of Escherichia coli and Its Phenotypic Rescue. | 2016 | PLoS ONE | pmid:27310825 |
Bartkoski S and Day M | Alpha-Lipoic Acid for Treatment of Diabetic Peripheral Neuropathy. | 2016 | Am Fam Physician | pmid:27175957 |
Costantino M et al. | Resolution of subchorionic hematoma and symptoms of threatened miscarriage using vaginal alpha lipoic acid or progesterone: clinical evidences. | 2016 | Eur Rev Med Pharmacol Sci | pmid:27160142 |
Cronan JE | Assembly of Lipoic Acid on Its Cognate Enzymes: an Extraordinary and Essential Biosynthetic Pathway. | 2016 | Microbiol. Mol. Biol. Rev. | pmid:27074917 |
Ying Z et al. | Lipoicmethylenedioxyphenol Reduces Experimental Atherosclerosis through Activation of Nrf2 Signaling. | 2016 | PLoS ONE | pmid:26859892 |
Moon HS | Chemopreventive Effects of Alpha Lipoic Acid on Obesity-Related Cancers. | 2016 | Ann. Nutr. Metab. | pmid:26829711 |
Uchida R et al. | Investigation of Enantioselective Membrane Permeability of α-Lipoic Acid in Caco-2 and MDCKII Cell. | 2016 | Int J Mol Sci | pmid:26821014 |
Abdelkarem HM et al. | Alleviation of bone markers in rats induced nano-zinc oxide by qurecetin and α-lipolic acid. | 2016 | Toxicol. Mech. Methods | pmid:27785948 |
Gurcay AG et al. | Comparative Biochemical and Motor Function Analysis of Alpha Lipoic Acid and N-Acetyl Cysteine Treatment on Rats with Experimental Spinal Cord Injury. | 2016 | Turk Neurosurg | pmid:26768878 |
Hwang S et al. | Inhibitory Effects of α-Lipoic Acid on Oxidative Stress-Induced Adipogenesis in Orbital Fibroblasts From Patients With Graves Ophthalmopathy. | 2016 | Medicine (Baltimore) | pmid:26765462 |
Wang J et al. | Xenobiotics and loss of tolerance in primary biliary cholangitis. | 2016 | World J. Gastroenterol. | pmid:26755880 |
Ströher E et al. | Glutaredoxin S15 Is Involved in Fe-S Cluster Transfer in Mitochondria Influencing Lipoic Acid-Dependent Enzymes, Plant Growth, and Arsenic Tolerance in Arabidopsis. | 2016 | Plant Physiol. | pmid:26672074 |
Sun B et al. | Robust, active tumor-targeting and fast bioresponsive anticancer nanotherapeutics based on natural endogenous materials. | 2016 | Acta Biomater | pmid:27576338 |
Bilska-Wilkosz A et al. | The effect of lipoic acid administration on the urinary excretion of thiocyanate in rats exposed to potassium cyanide. | 2015 Jan-Feb | Acta Pol Pharm | pmid:25850200 |
Zalejska-Fiolka J et al. | The Influence of α-Lipoic Acid and Garlic Administration on Biomarkers of Oxidative Stress and Inflammation in Rabbits Exposed to Oxidized Nutrition Oils. | 2015 | Biomed Res Int | pmid:26634212 |
Chaudhary P et al. | Lipoic acid reduces inflammation in a mouse focal cortical experimental autoimmune encephalomyelitis model. | 2015 | J. Neuroimmunol. | pmid:26616873 |
Nebbioso M et al. | Biomolecular Modulation of Neurodegenerative Events during Ageing. | 2015 | Oxid Med Cell Longev | pmid:26583065 |
Xiong S et al. | PGC-1α Modulates Telomere Function and DNA Damage in Protecting against Aging-Related Chronic Diseases. | 2015 | Cell Rep | pmid:26299964 |
Okanović A et al. | Alpha-lipoic acid reduces body weight and regulates triglycerides in obese patients with diabetes mellitus. | 2015 | Med Glas (Zenica) | pmid:26276648 |
Verma H and Garg R | Comment on "Alpha-Lipoic Acid and Antioxidant Diet Help to Improve Endothelial Dysfunction in Adolescents with Type 1 Diabetes: A Pilot Trial". | 2015 | J Diabetes Res | pmid:26273673 |
de Queiroz TM et al. | α-Lipoic acid reduces neurogenic hypertension by blunting oxidative stress-mediated increase in ADAM17. | 2015 | Am. J. Physiol. Heart Circ. Physiol. | pmid:26254330 |
Favero G et al. | A comparison of melatonin and α-lipoic acid in the induction of antioxidant defences in L6 rat skeletal muscle cells. | 2015 | Age (Dordr) | pmid:26250907 |
El Batsh MM et al. | Protective effects of alpha-lipoic acid against benzene induced toxicity in experimental rats. | 2015 | Eur Rev Med Pharmacol Sci | pmid:26221905 |
Scaramuzza A et al. | Alpha-Lipoic Acid and Antioxidant Diet Help to Improve Endothelial Dysfunction in Adolescents with Type 1 Diabetes: A Pilot Trial. | 2015 | J Diabetes Res | pmid:26171398 |
Zou H et al. | Alpha-lipoic acid protects against cadmium-induced hepatotoxicity via calcium signalling and gap junctional intercellular communication in rat hepatocytes. | 2015 | J Toxicol Sci | pmid:26165643 |
Çakır T et al. | The effect of alpha lipoic acid on rat kidneys in methotrexate induced oxidative injury. | 2015 | Eur Rev Med Pharmacol Sci | pmid:26125279 |
Kafara P et al. | Lipoic acid decreases Mcl-1, Bcl-xL and up regulates Bim on ovarian carcinoma cells leading to cell death. | 2015 | J Ovarian Res | pmid:26063499 |
Santos CL et al. | Lipoic acid and N-acetylcysteine prevent ammonia-induced inflammatory response in C6 astroglial cells: The putative role of ERK and HO1 signaling pathways. | 2015 | Toxicol In Vitro | pmid:26043815 |
Liu N et al. | Microwave-Assisted Resolution of α-Lipoic Acid Catalyzed by an Ionic Liquid Co-Lyophilized Lipase. | 2015 | Molecules | pmid:26035096 |
Palacios-Sánchez B et al. | Alpha lipoic acid efficacy in burning mouth syndrome. A controlled clinical trial. | 2015 | Med Oral Patol Oral Cir Bucal | pmid:26034927 |
Zhao L et al. | Lipoamide Acts as an Indirect Antioxidant by Simultaneously Stimulating Mitochondrial Biogenesis and Phase II Antioxidant Enzyme Systems in ARPE-19 Cells. | 2015 | PLoS ONE | pmid:26030919 |
Tong X et al. | Activation of hepatic CREBH and Insig signaling in the anti-hypertriglyceridemic mechanism of R-α-lipoic acid. | 2015 | J. Nutr. Biochem. | pmid:26007286 |
Zehnpfennig B et al. | Interaction of α-Lipoic Acid with the Human Na+/Multivitamin Transporter (hSMVT). | 2015 | J. Biol. Chem. | pmid:25971966 |
Agostinis C et al. | The combination of N-acetyl cysteine, alpha-lipoic acid, and bromelain shows high anti-inflammatory properties in novel in vivo and in vitro models of endometriosis. | 2015 | Mediators Inflamm. | pmid:25960622 |
Yildirim CH et al. | Alpha-lipoic acid inhibits peridural fibrosis following laminectomy through the inactivation of TGF-β1, PDGF, PAI-1 and IL-6 expressions. | 2015 | Turk Neurosurg | pmid:25640552 |
Cao X and Cronan JE | The Streptomyces coelicolor lipoate-protein ligase is a circularly permuted version of the Escherichia coli enzyme composed of discrete interacting domains. | 2015 | J. Biol. Chem. | pmid:25631049 |
Huerta AE et al. | Effects of α-lipoic acid and eicosapentaenoic acid in overweight and obese women during weight loss. | 2015 | Obesity (Silver Spring) | pmid:25594166 |
Berkowitz BA et al. | Oxidative stress and light-evoked responses of the posterior segment in a mouse model of diabetic retinopathy. | 2015 | Invest. Ophthalmol. Vis. Sci. | pmid:25574049 |
Ying Z et al. | Alpha-lipoic acid activates eNOS through activation of PI3-kinase/Akt signaling pathway. | 2015 | Vascul. Pharmacol. | pmid:25460366 |
Ergür BU et al. | The effects of α-lipoic acid on aortic injury and hypertension in the rat remnant kidney (5/6 nephrectomy) model. | 2015 | Anatol J Cardiol | pmid:25430409 |
Dominguez JM et al. | Combination therapies prevent the neuropathic, proinflammatory characteristics of bone marrow in streptozotocin-induced diabetic rats. | 2015 | Diabetes | pmid:25204979 |
Steliou K et al. | Bioprotective carnitinoids: lipoic acid, butyrate, and mitochondria-targeting to treat radiation injury: mitochondrial drugs come of age. | 2015 | Drug Dev. Res. | pmid:26109467 |
Parameshwaran K et al. | Antioxidant-mediated reversal of oxidative damage in mouse modeling of complex I inhibition. | 2015 | Drug Dev. Res. | pmid:25847731 |
Pilar Valdecantos M et al. | Essential role of Nrf2 in the protective effect of lipoic acid against lipoapoptosis in hepatocytes. | 2015 | Free Radic. Biol. Med. | pmid:25841776 |
Zhong Y et al. | Reversibly crosslinked hyaluronic acid nanoparticles for active targeting and intelligent delivery of doxorubicin to drug resistant CD44+ human breast tumor xenografts. | 2015 | J Control Release | pmid:25596560 |
Li G et al. | Alpha-lipoic acid exerts anti-inflammatory effects on lipopolysaccharide-stimulated rat mesangial cells via inhibition of nuclear factor kappa B (NF-κB) signaling pathway. | 2015 | Inflammation | pmid:24962643 |
Isaac VL et al. | Rheology as a Tool to Predict the Release of Alpha-Lipoic Acid from Emulsions Used for the Prevention of Skin Aging. | 2015 | Biomed Res Int | pmid:26788510 |
Li BJ et al. | Effect of lipoic acid combined with paclitaxel on breast cancer cells. | 2015 | Genet. Mol. Res. | pmid:26782439 |
Ma Q et al. | Molecular Mechanisms of Lipoic Acid Protection against Aflatoxin Bâ‚-Induced Liver Oxidative Damage and Inflammatory Responses in Broilers. | 2015 | Toxins (Basel) | pmid:26694462 |
Wood SH et al. | Transcriptome analysis in calorie-restricted rats implicates epigenetic and post-translational mechanisms in neuroprotection and aging. | 2015 | Genome Biol. | pmid:26694192 |