Lipoic acid is a lipid of Fatty Acyls (FA) class.
We collected disease MeSH terms mapped to the references associated with Lipoic acid
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Burner U et al. | Kinetics of oxidation of aliphatic and aromatic thiols by myeloperoxidase compounds I and II. | 1999 | FEBS Lett. | pmid:10025950 |
Kozlov AV et al. | Dihydrolipoic acid maintains ubiquinone in the antioxidant active form by two-electron reduction of ubiquinone and one-electron reduction of ubisemiquinone. | 1999 | Arch. Biochem. Biophys. | pmid:10049509 |
Anuradha B and Varalakshmi P | Protective role of DL-alpha-lipoic acid against mercury-induced neural lipid peroxidation. | 1999 | Pharmacol. Res. | pmid:10051379 |
Hofmann MA et al. | Peripheral blood mononuclear cells isolated from patients with diabetic nephropathy show increased activation of the oxidative-stress sensitive transcription factor NF-kappaB. | 1999 | Diabetologia | pmid:10064103 |
Traber KE et al. | Anti-rheumatic compound aurothioglucose inhibits tumor necrosis factor-alpha-induced HIV-1 replication in latently infected OM10.1 and Ach2 cells. | 1999 | Int. Immunol. | pmid:10069412 |
Breithaupt-Grögler K et al. | Dose-proportionality of oral thioctic acid--coincidence of assessments via pooled plasma and individual data. | 1999 | Eur J Pharm Sci | pmid:10072479 |
Conlon BJ et al. | Attenuation of aminoglycoside-induced cochlear damage with the metabolic antioxidant alpha-lipoic acid. | 1999 | Hear. Res. | pmid:10082281 |
Dubel L et al. | Autoepitope mapping and reactivity of autoantibodies to the dihydrolipoamide dehydrogenase-binding protein (E3BP) and the glycine cleavage proteins in primary biliary cirrhosis. | 1999 | Hepatology | pmid:10094940 |
Keegan A et al. | Effects of diabetes and treatment with the antioxidant alpha-lipoic acid on endothelial and neurogenic responses of corpus cavernosum in rats. | 1999 | Diabetologia | pmid:10096788 |
Khanna S et al. | Alpha-lipoic acid supplementation: tissue glutathione homeostasis at rest and after exercise. | 1999 | J. Appl. Physiol. | pmid:10194202 |
Fischer S et al. | Hypoxia induces permeability in brain microvessel endothelial cells via VEGF and NO. | 1999 | Am. J. Physiol. | pmid:10199811 |
Khamaisi M et al. | Lipoic acid acutely induces hypoglycemia in fasting nondiabetic and diabetic rats. | 1999 | Metab. Clin. Exp. | pmid:10206446 |
Palmer JM et al. | T cell responses to the putative dominant autoepitope in primary biliary cirrhosis (PBC). | 1999 | Clin. Exp. Immunol. | pmid:10209517 |
Marley R et al. | Lipoic acid prevents development of the hyperdynamic circulation in anesthetized rats with biliary cirrhosis. | 1999 | Hepatology | pmid:10216116 |
Beekman NJ et al. | Highly immunogenic and fully synthetic peptide-carrier constructs targetting GnRH. | 1999 | Vaccine | pmid:10217605 |
Hong YS et al. | The inhibitory effects of lipoic compounds on mammalian pyruvate dehydrogenase complex and its catalytic components. | 1999 | Free Radic. Biol. Med. | pmid:10218658 |
Rybak LP et al. | Dose dependent protection by lipoic acid against cisplatin-induced ototoxicity in rats: antioxidant defense system. | 1999 | Toxicol. Sci. | pmid:10220857 |
Balijepalli S et al. | Inhibition of mitochondrial complex I by haloperidol: the role of thiol oxidation. | 1999 | Neuropharmacology | pmid:10221760 |
Mitsui Y et al. | Alpha-lipoic acid provides neuroprotection from ischemia-reperfusion injury of peripheral nerve. | 1999 | J. Neurol. Sci. | pmid:10223404 |
Novotny L et al. | Polarographic properties and potential carcinogenicity of some natural nucleosides and their synthetic analogues. | 1999 | Bioelectrochem Bioenerg | pmid:10228579 |
Khanna S et al. | Cytokine-induced glucose uptake in skeletal muscle: redox regulation and the role of alpha-lipoic acid. | 1999 | Am. J. Physiol. | pmid:10233023 |
Reche P and Perham RN | Structure and selectivity in post-translational modification: attaching the biotinyl-lysine and lipoyl-lysine swinging arms in multifunctional enzymes. | 1999 | EMBO J. | pmid:10329614 |
Konrad T et al. | alpha-Lipoic acid treatment decreases serum lactate and pyruvate concentrations and improves glucose effectiveness in lean and obese patients with type 2 diabetes. | 1999 | Diabetes Care | pmid:10333946 |
Junquera E and Aicart E | Thermodynamic analysis of the binding of a hepatoprotectant drug, thioctic acid, by beta-cyclodextrin. | 1999 | J Pharm Sci | pmid:10350499 |
Otto DM et al. | Regulation of cytochrome P4501A metabolism by glutathione. | 1999 | Pharmacol. Toxicol. | pmid:10361976 |
Wu L and de Champlain J | Superoxide anion-induced formation of inositol phosphates involves tyrosine kinase activation in smooth muscle cells from rat mesenteric artery. | 1999 | Biochem. Biophys. Res. Commun. | pmid:10362493 |
Vilas GL et al. | Effect of alpha lipoic acid amide on hexachlorobenzene porphyria. | 1999 | Biochem. Mol. Biol. Int. | pmid:10365252 |
Shohami E et al. | Closed head injury in the rat induces whole body oxidative stress: overall reducing antioxidant profile. | 1999 | J. Neurotrauma | pmid:10369557 |
Di Rocco A | A randomized, double-blind, placebo-controlled trial of deprenyl and thiotic acid in HIV-associated cognitive impairment. | 1999 | Neurology | pmid:10371553 |
Roesler R et al. | A randomized, double-blind, placebo-controlled trial of deprenyl and thiotic acid in HIV-associated cognitive impairment. | 1999 | Neurology | pmid:10371554 |
Sen CK et al. | Fas mediated apoptosis of human Jurkat T-cells: intracellular events and potentiation by redox-active alpha-lipoic acid. | 1999 | Cell Death Differ. | pmid:10381641 |
Guilhaudis L et al. | Investigation of the local structure and dynamics of the H subunit of the mitochondrial glycine decarboxylase using heteronuclear NMR spectroscopy. | 1999 | Biochemistry | pmid:10387079 |
Haak ES et al. | The effect of alpha-lipoic acid on the neurovascular reflex arc in patients with diabetic neuropathy assessed by capillary microscopy. | 1999 | Microvasc. Res. | pmid:10388600 |
Rathmann W et al. | [Drug prescriptions and costs in diabetic polyneuropathy]. | 1999 | Dtsch. Med. Wochenschr. | pmid:10394347 |
Roche O et al. | Theoretical study of the conformation of the H-protein lipoamide arm as a function of its terminal group. | 1999 | Proteins | pmid:10398369 |
Tirosh O et al. | Neuroprotective effects of alpha-lipoic acid and its positively charged amide analogue. | 1999 | Free Radic. Biol. Med. | pmid:10401605 |
Borcea V et al. | alpha-Lipoic acid decreases oxidative stress even in diabetic patients with poor glycemic control and albuminuria. | 1999 | Free Radic. Biol. Med. | pmid:10401614 |
Aevarsson A et al. | Crystal structure of 2-oxoisovalerate and dehydrogenase and the architecture of 2-oxo acid dehydrogenase multienzyme complexes. | 1999 | Nat. Struct. Biol. | pmid:10426958 |
Strokov IA et al. | [The efficacy of the intravenous administration of the trometamol salt of thioctic (alpha-lipoic) acid in diabetic neuropathy]. | 1999 | Zh Nevrol Psikhiatr Im S S Korsakova | pmid:10441861 |
Gurer H et al. | Antioxidant role of alpha-lipoic acid in lead toxicity. | 1999 | Free Radic. Biol. Med. | pmid:10443922 |
Reddi AS et al. | Plasma alpha-lipoic acid and total glutathione levels in patients on maintenance hemodialysis. | 1999 | Nephron | pmid:10450040 |
Jacob S et al. | Oral administration of RAC-alpha-lipoic acid modulates insulin sensitivity in patients with type-2 diabetes mellitus: a placebo-controlled pilot trial. | 1999 | Free Radic. Biol. Med. | pmid:10468203 |
Jordan F | Interplay of organic and biological chemistry in understanding coenzyme mechanisms: example of thiamin diphosphate-dependent decarboxylations of 2-oxo acids. | 1999 | FEBS Lett. | pmid:10471796 |
Gueguen V et al. | Structural and functional characterization of H protein mutants of the glycine decarboxylase complex. | 1999 | J. Biol. Chem. | pmid:10473591 |
Ziegler D et al. | Treatment of symptomatic diabetic polyneuropathy with the antioxidant alpha-lipoic acid: a 7-month multicenter randomized controlled trial (ALADIN III Study). ALADIN III Study Group. Alpha-Lipoic Acid in Diabetic Neuropathy. | 1999 | Diabetes Care | pmid:10480774 |
Rudich A et al. | Lipoic acid protects against oxidative stress induced impairment in insulin stimulation of protein kinase B and glucose transport in 3T3-L1 adipocytes. | 1999 | Diabetologia | pmid:10491755 |
Reljanovic M et al. | Treatment of diabetic polyneuropathy with the antioxidant thioctic acid (alpha-lipoic acid): a two year multicenter randomized double-blind placebo-controlled trial (ALADIN II). Alpha Lipoic Acid in Diabetic Neuropathy. | 1999 | Free Radic. Res. | pmid:10499773 |
Kishi Y et al. | Alpha-lipoic acid: effect on glucose uptake, sorbitol pathway, and energy metabolism in experimental diabetic neuropathy. | 1999 | Diabetes | pmid:10512372 |
Anuradha B and Varalakshmi P | Activities of glucose-metabolizing enzymes in experimental neurotoxic models with lipoate as an alleviator. | 1999 Nov-Dec | J Appl Toxicol | pmid:10547622 |