| MeSH term | MeSH ID | Detail |
|---|---|---|
| Kidney Calculi | D007669 | 7 associated lipids |
| Weight Gain | D015430 | 101 associated lipids |
| Burning Mouth Syndrome | D002054 | 2 associated lipids |
| Cell Transformation, Neoplastic | D002471 | 126 associated lipids |
| Chemical and Drug Induced Liver Injury | D056486 | 39 associated lipids |
| Obesity | D009765 | 29 associated lipids |
| Peritonitis | D010538 | 38 associated lipids |
| Alzheimer Disease | D000544 | 76 associated lipids |
| Thyroid Neoplasms | D013964 | 33 associated lipids |
| Intervertebral Disc Displacement | D007405 | 2 associated lipids |
Lipoic acid
Lipoic acid is a lipid of Fatty Acyls (FA) class.
Cross Reference
There are no associated biomedical information in the current reference collection.
Current reference collection contains 18962 references associated with Lipoic acid in LipidPedia. Due to lack of full text of references or no associated biomedical terms are recognized in our current text-mining method, we cannot extract any biomedical terms related to diseases, pathways, locations, functions, genes, lipids, and animal models from the associated reference collection.
Users can download the reference list at the bottom of this page and read the reference manually to find out biomedical information.
Here are additional resources we collected from PubChem and MeSH for Lipoic acid
Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with Lipoic acid
PubChem Biomolecular Interactions and Pathways
NCBI Entrez Crosslinks
All references with Lipoic acid
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Ma QL et al. | Loss of MAP function leads to hippocampal synapse loss and deficits in the Morris Water Maze with aging. | 2014 | J. Neurosci. | pmid:24849348 |
| Macias-Barragan J et al. | [Effects of alpha lipoic acid and pirfenidone on liver cells antioxidant modulation against oxidative damage]. | 2014 | Rev Med Chil | pmid:25693438 |
| Mendes PR et al. | Effect of alpha lipoic acid on the blood cell count and iron kinetics in hypertensive patients. | 2014 | Nutr Hosp | pmid:25617577 |
| Thakurta IG et al. | Combination of N-acetylcysteine, α-lipoic acid and α-tocopherol substantially prevents the brain synaptosomal alterations and memory and learning deficits of aged rats. | 2014 | Exp. Gerontol. | pmid:24291247 |
| Carter SE et al. | The role of prostaglandin and antioxidant availability in recovery from forearm ischemia-reperfusion injury in humans. | 2014 | J. Hypertens. | pmid:24296519 |
| Al-Rasheed NM et al. | Prophylactic role of α-lipoic acid and vitamin E against zinc oxide nanoparticles induced metabolic and immune disorders in rat's liver. | 2014 | Eur Rev Med Pharmacol Sci | pmid:24992626 |
| Scumpia PO et al. | Alpha-lipoic acid effects on brain glial functions accompanying double-stranded RNA antiviral and inflammatory signaling. | 2014 | Neurochem. Int. | pmid:24269587 |
| Thomas S et al. | Stability, cutaneous delivery, and antioxidant potential of a lipoic acid and α-tocopherol codrug incorporated in microemulsions. | 2014 | J Pharm Sci | pmid:24961388 |
| Lim KS et al. | Effect of polymer-free TiO2 stent coated with abciximab or alpha lipoic acid in porcine coronary restenosis model. | 2014 | J Cardiol | pmid:24852847 |
| Hatami S et al. | Total oxidative status of mouse vitrified pre-antral follicles with pre-treatment of alpha lipoic acid. | 2014 | Iran. Biomed. J. | pmid:24842145 |
| Fu Y et al. | In vivo detection of a novel endogenous etheno-DNA adduct derived from arachidonic acid and the effects of antioxidants on its formation. | 2014 | Free Radic. Biol. Med. | pmid:24816294 |
| Connell BJ et al. | UPEI-300, a conjugate of lipoic acid and edaravone, mediates neuroprotection in ischemia/reperfusion. | 2014 | Neurosci. Lett. | pmid:24394910 |
| Schwartz L et al. | Metabolic treatment of cancer: intermediate results of a prospective case series. | 2014 | Anticancer Res. | pmid:24511042 |
| Nicolson GL | Mitochondrial dysfunction and chronic disease: treatment with natural supplements. | 2014 | Altern Ther Health Med | pmid:24473982 |
| Ali SO et al. | Modulatory effects of curcumin, silybin-phytosome and alpha-R-lipoic acid against thioacetamide-induced liver cirrhosis in rats. | 2014 | Chem. Biol. Interact. | pmid:24704557 |
| He F et al. | Comment on Xu et al.: Meta-analysis of methylcobalamin alone and in combination with lipoic acid in patients with diabetic peripheral neuropathy. | 2014 | Diabetes Res. Clin. Pract. | pmid:24602352 |
| Sherif S et al. | The clinical efficacy of cosmeceutical application of liquid crystalline nanostructured dispersions of alpha lipoic acid as anti-wrinkle. | 2014 | Eur J Pharm Biopharm | pmid:24056055 |
| Nasole E et al. | Effects of alpha lipoic acid and its R+ enantiomer supplemented to hyperbaric oxygen therapy on interleukin-6, TNF-α and EGF production in chronic leg wound healing. | 2014 | J Enzyme Inhib Med Chem | pmid:23360079 |
| Liu J et al. | Reloading functionally ameliorates disuse-induced muscle atrophy by reversing mitochondrial dysfunction, and similar benefits are gained by administering a combination of mitochondrial nutrients. | 2014 | Free Radic. Biol. Med. | pmid:24418157 |
| Amin KA et al. | Oxidative hepatotoxicity effects of monocrotaline and its amelioration by lipoic acid, S-adenosyl methionine and vitamin E. | 2014 | J Complement Integr Med | pmid:24413220 |
| Zygmunt M et al. | Anti-inflammatory activity of lipoic acid in mice peritonitis model. | 2013 Sep-Oct | Acta Pol Pharm | pmid:24147369 |
| Koriyama Y et al. | Anti-inflammatory effects of lipoic acid through inhibition of GSK-3β in lipopolysaccharide-induced BV-2 microglial cells. | 2013 Sep-Oct | Neurosci. Res. | pmid:23892131 |
| Sayın M et al. | The dose-dependent neuroprotective effect of alpha-lipoic acid in experimental spinal cord injury. | 2013 Jul-Aug | Neurol. Neurochir. Pol. | pmid:23986424 |
| Durand M and Mach N | [Alpha lipoic acid and its antioxidant against cancer and diseases of central sensitization]. | 2013 Jul-Aug | Nutr Hosp | pmid:23889618 |
| Haber A et al. | Combating diabetes complications by 1-Fe, a corrole-based catalytic antioxidant. | 2013 Jul-Aug | J. Diabetes Complicat. | pmid:23602197 |
| Mitkov MD et al. | Effect of transdermal testosterone or alpha-lipoic acid on erectile dysfunction and quality of life in patients with type 2 diabetes mellitus. | 2013 Jan-Mar | Folia Med (Plovdiv) | pmid:23905488 |
| Nebbioso M et al. | Mechanisms of ocular neuroprotection by antioxidant molecules in animal models. | 2013 Jan-Mar | J. Biol. Regul. Homeost. Agents | pmid:23489699 |
| Leu JG et al. | Epigallocatechin-3-gallate combined with alpha lipoic acid attenuates high glucose-induced receptor for advanced glycation end products (RAGE) expression in human embryonic kidney cells. | 2013 Apr-Jun | An. Acad. Bras. Cienc. | pmid:23780308 |
| Kondo H et al. | β-Adrenergic signaling stimulates osteoclastogenesis via reactive oxygen species. | 2013 | Am. J. Physiol. Endocrinol. Metab. | pmid:23169789 |
| Castro MC et al. | Lipoic acid prevents liver metabolic changes induced by administration of a fructose-rich diet. | 2013 | Biochim. Biophys. Acta | pmid:23085069 |
| Arambašić J et al. | Alpha-lipoic acid upregulates antioxidant enzyme gene expression and enzymatic activity in diabetic rat kidneys through an O-GlcNAc-dependent mechanism. | 2013 | Eur J Nutr | pmid:23064900 |
| Villasana LE et al. | Effects of alpha-lipoic acid on associative and spatial memory of sham-irradiated and 56Fe-irradiated C57BL/6J male mice. | 2013 | Pharmacol. Biochem. Behav. | pmid:23051895 |
| Mıcılı SC et al. | Effects of lipoic acid in an experimentally induced hypertensive and diabetic rat model. | 2013 | Clin. Exp. Hypertens. | pmid:23072377 |
| Külkamp-Guerreiro IC et al. | Influence of nanoencapsulation on the sensory properties of cosmetic formulations containing lipoic acid. | 2013 | Int J Cosmet Sci | pmid:23075068 |
| Baky NA et al. | Induction of inflammation, DNA damage and apoptosis in rat heart after oral exposure to zinc oxide nanoparticles and the cardioprotective role of α-lipoic acid and vitamin E. | 2013 | Drug Res (Stuttg) | pmid:23532625 |
| Ong SL et al. | The effect of alpha-lipoic acid on mitochondrial superoxide and glucocorticoid-induced hypertension. | 2013 | Oxid Med Cell Longev | pmid:23533693 |
| Zhou L et al. | α-Lipoic acid ameliorates mitochondrial impairment and reverses apoptosis in FABP3-overexpressing embryonic cancer cells. | 2013 | J. Bioenerg. Biomembr. | pmid:23536161 |
| Haack TB et al. | Homozygous missense mutation in BOLA3 causes multiple mitochondrial dysfunctions syndrome in two siblings. | 2013 | J. Inherit. Metab. Dis. | pmid:22562699 |
| Inui T et al. | Clinical experience of integrative cancer immunotherapy with GcMAF. | 2013 | Anticancer Res. | pmid:23780980 |
| Bérczi A et al. | Dihydrolipoic acid reduces cytochrome b561 proteins. | 2013 | Eur. Biophys. J. | pmid:22526465 |
| Nishino A et al. | The role of oxygen intermediates in the retention time of diacetyl adaptation in the nematode Caenorhabditis elegans. | 2013 | J Exp Zool A Ecol Genet Physiol | pmid:23733487 |
| Strokov IA et al. | [Efficacy of thiolepta in diabetic polyneuropathy: results of the study ETIKA]. | 2013 | Zh Nevrol Psikhiatr Im S S Korsakova | pmid:23739501 |
| El-Beshbishy HA et al. | Lipoic acid mitigates bisphenol A-induced testicular mitochondrial toxicity in rats. | 2013 | Toxicol Ind Health | pmid:22623521 |
| Somi MH et al. | Lipoic acid prevents hepatic and intestinal damage induced by obstruction of the common bile duct in rats. | 2013 | Eur Rev Med Pharmacol Sci | pmid:23740441 |
| Inman DM et al. | α-Lipoic acid antioxidant treatment limits glaucoma-related retinal ganglion cell death and dysfunction. | 2013 | PLoS ONE | pmid:23755225 |
| Karaarslan U et al. | Alpha lipoic acid intoxication, treatment and outcome. | 2013 | Clin Toxicol (Phila) | pmid:23713820 |
| Ishiki M et al. | Impact of divergent effects of astaxanthin on insulin signaling in L6 cells. | 2013 | Endocrinology | pmid:23715867 |
| Rhoads RP et al. | Nutritional interventions to alleviate the negative consequences of heat stress. | 2013 | Adv Nutr | pmid:23674792 |
| Jin HB et al. | Lipoic acid attenuates the expression of adhesion molecules by increasing endothelial nitric-oxide synthase activity. | 2013 | Mol. Biol. Rep. | pmid:23054010 |
| Zhang H et al. | Robust and specific ratiometric biosensing using a copper-free clicked quantum dot-DNA aptamer sensor. | 2013 | Nanoscale | pmid:24056667 |
| Jo SH et al. | Alpha-lipoic acid for the prevention of contrast-induced nephropathy in patients undergoing coronary angiography: the ALIVE study - a prospective randomized trial. | 2013 | Cardiology | pmid:23988855 |
| Chen BY et al. | Dietary α-lipoic acid prevents UVB-induced corneal and conjunctival degeneration through multiple effects. | 2013 | Invest. Ophthalmol. Vis. Sci. | pmid:23989186 |
| Tsai CJ et al. | Dispersive liquid-liquid microextraction combined with microwave-assisted derivatization for determining lipoic acid and its metabolites in human urine. | 2013 | J Chromatogr A | pmid:23993748 |
| Yi X et al. | Reversal of obesity-induced hypertriglyceridemia by (R)-α-lipoic acid in ZDF (fa/fa) rats. | 2013 | Biochem. Biophys. Res. Commun. | pmid:23994635 |
| Zhivolupov SA et al. | [Metabolic therapy in neurology]. | 2013 | Zh Nevrol Psikhiatr Im S S Korsakova | pmid:23994919 |
| Battisti E et al. | Alpha lipoic acid and superoxide dismutase in the treatment of chronic low back pain. | 2013 | Eur J Phys Rehabil Med | pmid:23860422 |
| Wijayanti HB et al. | Reduction of aggregation of β-lactoglobulin during heating by dihydrolipoic acid. | 2013 | J. Dairy Res. | pmid:23866304 |
| Dudek M et al. | Are anti-inflammatory properties of lipoic acid associated with the formation of hydrogen sulfide? | 2013 | Pharmacol Rep | pmid:24145097 |
| Steele ML et al. | Effect of Nrf2 activators on release of glutathione, cysteinylglycine and homocysteine by human U373 astroglial cells. | 2013 | Redox Biol | pmid:24191238 |
| Lu C et al. | Synthesis of lipoic acid-peptide conjugates and their effect on collagen and melanogenesis. | 2013 | Eur J Med Chem | pmid:24090916 |
| Chan WH et al. | Impact of dihydrolipoic acid on mouse embryonic stem cells and related regulatory mechanisms. | 2013 | Environ. Toxicol. | pmid:21462292 |
| Benson A | A conversation with Andrew Benson: reflections on the discovery of the Calvin-Benson cycle. | 2013 | Photosyn. Res. | pmid:23269523 |
| Cai X et al. | Pre-protective effect of lipoic acid on injury induced by H2O2 in IPEC-J2 cells. | 2013 | Mol. Cell. Biochem. | pmid:23440503 |
| Zhang H et al. | Improving development of cloned goat embryos by supplementing α-lipoic acid to oocyte in vitro maturation medium. | 2013 | Theriogenology | pmid:23743066 |
| Huang Z et al. | Short-term continuous subcutaneous insulin infusion combined with insulin sensitizers rosiglitazone, metformin, or antioxidant α-lipoic acid in patients with newly diagnosed type 2 diabetes mellitus. | 2013 | Diabetes Technol. Ther. | pmid:23991629 |
| Carmine A et al. | Comparison of lipoic and asparagusic acid for surface-initiated disulfide-exchange polymerization. | 2013 | Chemistry | pmid:23893874 |
| Rocamonde B et al. | Lipoic acid treatment after brain injury: study of the glial reaction. | 2013 | Clin. Dev. Immunol. | pmid:24302959 |
| Uyar IS et al. | Alpha lipoic acid attenuates inflammatory response during extracorporeal circulation. | 2013 | Cardiovasc J Afr | pmid:24240384 |
| Ahmadi A et al. | Effect of alpha-lipoic acid and vitamin E supplementation on oxidative stress, inflammation, and malnutrition in hemodialysis patients. | 2013 | Iran J Kidney Dis | pmid:24241092 |
| Fedin AI et al. | [Pharmacotherapy of endothelial dysfunction in patients with atherosclerotic brain ischemia]. | 2013 | Zh Nevrol Psikhiatr Im S S Korsakova | pmid:24300805 |
| Akman S et al. | Therapeutic effects of alpha lipoic acid and vitamin C on alveolar bone resorption after experimental periodontitis in rats: a biochemical, histochemical, and stereologic study. | 2013 | J. Periodontol. | pmid:22702517 |
| Maksymiak M et al. | Structural characterization of biocompatible lipoic acid-oligo-(3-hydroxybutyrate) conjugates by electrospray ionization mass spectrometry. | 2013 | Rapid Commun. Mass Spectrom. | pmid:23495024 |
| Xu Q et al. | Meta-analysis of methylcobalamin alone and in combination with lipoic acid in patients with diabetic peripheral neuropathy. | 2013 | Diabetes Res. Clin. Pract. | pmid:23664235 |
| Ledesma JC and Aragon CM | Acquisition and reconditioning of ethanol-induced conditioned place preference in mice is blocked by the Hâ‚‚Oâ‚‚ scavenger alpha lipoic acid. | 2013 | Psychopharmacology (Berl.) | pmid:22885873 |
| Milward MR et al. | Micronutrient modulation of NF-κB in oral keratinocytes exposed to periodontal bacteria. | 2013 | Innate Immun | pmid:22890546 |
| Kumar P and Dwivedi N | Proline catalyzed α-aminoxylation reaction in the synthesis of biologically active compounds. | 2013 | Acc. Chem. Res. | pmid:23148510 |
| Falkard B et al. | A key role for lipoic acid synthesis during Plasmodium liver stage development. | 2013 | Cell. Microbiol. | pmid:23490300 |
| Zara S et al. | Ibuprofen and lipoic acid conjugate neuroprotective activity is mediated by Ngb/Akt intracellular signaling pathway in Alzheimer's disease rat model. | 2013 | Gerontology | pmid:23428737 |
| Bobermin LD et al. | Lipoic acid protects C6 cells against ammonia exposure through Naâº-Kâº-Clâ» co-transporter and PKC pathway. | 2013 | Toxicol In Vitro | pmid:23880158 |
| Ji D et al. | α-Lipoic acid attenuates light insults to neurones. | 2013 | Biol. Pharm. Bull. | pmid:23811555 |
| Jiang T et al. | Lipoic acid restores age-associated impairment of brain energy metabolism through the modulation of Akt/JNK signaling and PGC1α transcriptional pathway. | 2013 | Aging Cell | pmid:23815272 |
| Peana AT et al. | Alpha-lipoic acid reduces ethanol self-administration in rats. | 2013 | Alcohol. Clin. Exp. Res. | pmid:23802909 |
| Yang L et al. | [Effect of alpha-lipoic acid combined with transient intensive insulin therapy on adipokine level in patients with type 2 diabetic perineuropathy]. | 2013 | Zhongguo Yi Xue Ke Xue Yuan Xue Bao | pmid:23827078 |
| Chen CL et al. | Potential of nonoral α-lipoic acid aqueous formulations to reduce ocular microvascular complications in a streptozotocin-induced diabetic rat model. | 2013 | J Ocul Pharmacol Ther | pmid:23848951 |
| Satsu H et al. | A sphingosine 1-phosphate receptor 2 selective allosteric agonist. | 2013 | Bioorg. Med. Chem. | pmid:23849205 |
| Lakhtin IuV | Comparative evaluation of short- and long-term treatment of periodontitis with alpha-lipoic acid. | 2013 | Georgian Med News | pmid:23787501 |
| Kumar S et al. | Lipoic acid prevents Cr(6+) induced cell transformation and the associated genomic dysregulation. | 2013 | Environ. Toxicol. Pharmacol. | pmid:23608068 |
| Sokołowska M et al. | The effect of lipoic acid on cyanate toxicity in different structures of the rat brain. | 2013 | Neurotox Res | pmid:23625581 |
| Li DW et al. | α-lipoic acid protects dopaminergic neurons against MPP+-induced apoptosis by attenuating reactive oxygen species formation. | 2013 | Int. J. Mol. Med. | pmid:23615851 |
| Li RJ et al. | Alpha-lipoic acid ameliorates oxidative stress by increasing aldehyde dehydrogenase-2 activity in patients with acute coronary syndrome. | 2013 | Tohoku J. Exp. Med. | pmid:23238616 |
| Kleinkauf-Rocha J et al. | Lipoic acid increases glutamate uptake, glutamine synthetase activity and glutathione content in C6 astrocyte cell line. | 2013 | Int. J. Dev. Neurosci. | pmid:23286972 |
| Panzella L et al. | Synthesis and bioactivity profile of 5-s-lipoylhydroxytyrosol-based multidefense antioxidants with a sizeable (poly)sulfide chain. | 2013 | J. Agric. Food Chem. | pmid:23256907 |
| Pinkerton NM et al. | Formation of stable nanocarriers by in situ ion pairing during block-copolymer-directed rapid precipitation. | 2013 | Mol. Pharm. | pmid:23259920 |
| Kaya-Dagistanli F et al. | The effects of alpha lipoic acid on liver cells damages and apoptosis induced by polyunsaturated fatty acids. | 2013 | Food Chem. Toxicol. | pmid:23200892 |
| Kursu VA et al. | Defects in mitochondrial fatty acid synthesis result in failure of multiple aspects of mitochondrial biogenesis in Saccharomyces cerevisiae. | 2013 | Mol. Microbiol. | pmid:24102902 |
| Tang G et al. | Hydrogen sulfide-induced inhibition of L-type Ca2+ channels and insulin secretion in mouse pancreatic beta cells. | 2013 | Diabetologia | pmid:23275972 |
| Kawano Y et al. | Increased oxidative stress may lead to impaired adaptive cytoprotection in the gastric mucosa of portal hypertensive rat. | 2013 | J. Gastroenterol. Hepatol. | pmid:23278350 |
| Moraes TB et al. | Role of catalase and superoxide dismutase activities on oxidative stress in the brain of a phenylketonuria animal model and the effect of lipoic acid. | 2013 | Cell. Mol. Neurobiol. | pmid:23232760 |
| Khadrawy YA et al. | The anticonvulant effect of cooling in comparison to α-lipoic acid: a neurochemical study. | 2013 | Neurochem. Res. | pmid:23389664 |
| Parsons TB et al. | Total synthesis of kottamide E. | 2013 | Chem. Commun. (Camb.) | pmid:23396320 |