Lipoic acid

Lipoic acid is a lipid of Fatty Acyls (FA) class.

Cross Reference

There are no associated biomedical information in the current reference collection.

Current reference collection contains 18962 references associated with Lipoic acid in LipidPedia. Due to lack of full text of references or no associated biomedical terms are recognized in our current text-mining method, we cannot extract any biomedical terms related to diseases, pathways, locations, functions, genes, lipids, and animal models from the associated reference collection.

Users can download the reference list at the bottom of this page and read the reference manually to find out biomedical information.


Here are additional resources we collected from PubChem and MeSH for Lipoic acid

Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Lipoic acid

MeSH term MeSH ID Detail
Hemolysis D006461 131 associated lipids
Stomach Ulcer D013276 75 associated lipids
Kidney Failure, Chronic D007676 51 associated lipids
Diabetes Mellitus D003920 90 associated lipids
Lead Poisoning D007855 4 associated lipids
Hearing Loss, Sensorineural D006319 8 associated lipids
Hypoxia D000860 23 associated lipids
Arrhythmias, Cardiac D001145 42 associated lipids
Acidosis, Lactic D000140 8 associated lipids
Lung Neoplasms D008175 171 associated lipids
Per page 10 20 50 100 | Total 177

PubChem Biomolecular Interactions and Pathways

NCBI Entrez Crosslinks

All references with Lipoic acid

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Per page 10 20 50 100 | Total 4476
Authors Title Published Journal PubMed Link
Vacchina P et al. Lipoic acid metabolism in Trypanosoma cruzi as putative target for chemotherapy. 2018 Exp. Parasitol. pmid:29409741
Fayyaz MH et al. Survival of buffalo bull spermatozoa: effect on structure and function due to alpha-lipoic acid and cholesterol-loaded cyclodextrin. 2017 Andrologia pmid:27491811
El-Sayed EM et al. Alpha lipoic acid prevents doxorubicin-induced nephrotoxicity by mitigation of oxidative stress, inflammation, and apoptosis in rats. 2017 J. Biochem. Mol. Toxicol. pmid:28598563
How SC et al. Cell-targeted, dual reduction- and pH-responsive saccharide/lipoic acid-modified poly(L-lysine) and poly(acrylic acid) polyionic complex nanogels for drug delivery. 2017 Colloids Surf B Biointerfaces pmid:28267669
Bernardinelli E et al. Mis-targeting of the mitochondrial protein LIPT2 leads to apoptotic cell death. 2017 PLoS ONE pmid:28628643
Cichoń M et al. [Effect of α-lipoic acid on free radical processes in serum of rats on high fat diet]. 2017 Med Pr pmid:28512366
Al-Ghamdi MA et al. POTENTIAL ADMINISTRATION OF LIPOIC ACID AND COENZYME Q AGAINST ADIPOGENSIS: TARGET FOR WEIGHT REDUCTION. 2017 Afr J Tradit Complement Altern Med pmid:28480405
Bilska-Wilkosz A et al. Lipoic Acid as a Possible Pharmacological Source of Hydrogen Sulfide/Sulfane Sulfur. 2017 Molecules pmid:28257119
Luchetti R et al. Observational multicentric survey on carpal tunnel syndrome: demographic and clinical data from 34 Italian centers. 2017 Eur Rev Med Pharmacol Sci pmid:28239826
Zee T et al. α-Lipoic acid treatment prevents cystine urolithiasis in a mouse model of cystinuria. 2017 Nat. Med. pmid:28165480
Zhang T et al. Tang-Luo-Ning Improves Mitochondrial Antioxidase Activity in Dorsal Root Ganglia of Diabetic Rats: A Proteomics Study. 2017 Biomed Res Int pmid:28133612
Takeda T et al. α-Lipoic acid potentially targets AMP-activated protein kinase and energy production in the fetal brain to ameliorate dioxin-produced attenuation in fetal steroidogenesis. 2017 J Toxicol Sci pmid:28070105
Sun Y et al. Overproduction of α-Lipoic Acid by Gene Manipulated Escherichia coli. 2017 PLoS ONE pmid:28068366
Kangawa Y et al. Anti-inflammatory effects of the selective phosphodiesterase 3 inhibitor, cilostazol, and antioxidants, enzymatically-modified isoquercitrin and α-lipoic acid, reduce dextran sulphate sodium-induced colorectal mucosal injury in mice. 2017 Exp. Toxicol. Pathol. pmid:28089463
Polanski JF et al. Antioxidant therapy in the elderly with tinnitus. 2016 May-Jun Braz J Otorhinolaryngol pmid:26547700
Salvi A et al. Effect of Hydrogen Sulfide Donors on Intraocular Pressure in Rabbits. 2016 Jul-Aug J Ocul Pharmacol Ther pmid:27092593
Alpay M et al. Antileukemic effects of piperlongumine and alpha lipoic acid combination on Jurkat, MEC1 and NB4 cells in vitro. 2016 Apr-Jun J Cancer Res Ther pmid:27461609
Rousseau AS et al. α-Lipoic acid up-regulates expression of peroxisome proliferator-activated receptor β in skeletal muscle: involvement of the JNK signaling pathway. 2016 FASEB J. pmid:26655383
Choi JH et al. α-Lipoic Acid Inhibits Expression of IL-8 by Suppressing Activation of MAPK, Jak/Stat, and NF-κB in H. pylori-Infected Gastric Epithelial AGS Cells. 2016 Yonsei Med. J. pmid:26632410
Madias JE A-lipoic acid therapy mediated amelioration of sympathetic heart denervation in patients with takotsubo syndrome. 2016 J Cardiol pmid:26603324
Ali SO et al. Curcumin, Silybin Phytosome(®) and α-R-Lipoic Acid Mitigate Chronic Hepatitis in Rat by Inhibiting Oxidative Stress and Inflammatory Cytokines Production. 2016 Basic Clin. Pharmacol. Toxicol. pmid:26457982
Liang S et al. Role of Cyt-C/caspases-9,3, Bax/Bcl-2 and the FAS death receptor pathway in apoptosis induced by zinc oxide nanoparticles in human aortic endothelial cells and the protective effect by alpha-lipoic acid. 2016 Chem. Biol. Interact. pmid:27544635
Cheserek MJ et al. Cardioprotective effects of lipoic acid, quercetin and resveratrol on oxidative stress related to thyroid hormone alterations in long-term obesity. 2016 J. Nutr. Biochem. pmid:27260466
Fiore E et al. Effect of combined acetylmethionine, cyanocobalamin and α-lipoic acid on hepatic metabolism in high-yielding dairy cow. 2016 J. Dairy Res. pmid:27845016
Zieleniecki JL et al. Cell-Free Synthesis of a Functional Membrane Transporter into a Tethered Bilayer Lipid Membrane. 2016 Langmuir pmid:26910192
Harless L and Liang J Pharmacologic treatment for postviral olfactory dysfunction: a systematic review. 2016 Int Forum Allergy Rhinol pmid:26879592
Becucci L et al. Channel-forming activity of syringopeptin 25A in mercury-supported lipid bilayers with a phosphatidylcholine distal leaflet. 2016 Bioelectrochemistry pmid:26680109
Al-Matubsi HY et al. Effects of Lipoic Acid Supplementation on Activities of Cyclooxygenases and Levels of Prostaglandins E2 and F2α Metabolites, in the Offspring of Rats with Streptozotocin-Induced Diabetes. 2016 J Diabetes Res pmid:28042582
Moura FA et al. Colonic and Hepatic Modulation by Lipoic Acid and/or N-Acetylcysteine Supplementation in Mild Ulcerative Colitis Induced by Dextran Sodium Sulfate in Rats. 2016 Oxid Med Cell Longev pmid:27957238
Williams CA The effect of oxidative stress during exercise in the horse. 2016 J. Anim. Sci. pmid:27898872
Li Y and Monteiro-Riviere NA Mechanisms of cell uptake, inflammatory potential and protein corona effects with gold nanoparticles. 2016 Nanomedicine (Lond) pmid:27882809
Roberts JD et al. An Exploratory Investigation of Endotoxin Levels in Novice Long Distance Triathletes, and the Effects of a Multi-Strain Probiotic/Prebiotic, Antioxidant Intervention. 2016 Nutrients pmid:27869661
Tao Y et al. α-Lipoic Acid Treatment Improves Vision-Related Quality of Life in Patients with Dry Age-Related Macular Degeneration. 2016 Tohoku J. Exp. Med. pmid:27840374
Derosa G et al. A Clinical Trial about a Food Supplement Containing α-Lipoic Acid on Oxidative Stress Markers in Type 2 Diabetic Patients. 2016 Int J Mol Sci pmid:27801825
Zhang J and McCullough PA Lipoic Acid in the Prevention of Acute Kidney Injury. 2016 Nephron pmid:27603173
Arikan M et al. Histomorphometric and Ultrastructural Evaluation of Long-Term Alpha Lipoic Acid and Vitamin B12 Use After Experimental Sciatic Nerve Injury in Rats. 2016 Turk Neurosurg pmid:27476916
Niska K et al. Capping Agent-Dependent Toxicity and Antimicrobial Activity of Silver Nanoparticles: An In Vitro Study. Concerns about Potential Application in Dental Practice. 2016 Int J Med Sci pmid:27766027
Zhang L et al. Study on the clinical value of alprostadil combined with α-lipoic acid in treatment of type 2 diabetes mellitus patients with erectile dysfunction. 2016 Eur Rev Med Pharmacol Sci pmid:27735021
Zorzoli A et al. Staphylococcus aureus Tissue Infection During Sepsis Is Supported by Differential Use of Bacterial or Host-Derived Lipoic Acid. 2016 PLoS Pathog. pmid:27701474
Gao S et al. Oxidative stress increases the risk of pancreatic β cell damage in chronic renal hypertensive rats. 2016 Physiol Rep pmid:27535482
Güleş Ö and Eren Ü Protective role of alpha lipoic acid against polychlorobiphenyl (Aroclor 1254)-induced testicular toxicity in rats. 2016 Rom J Morphol Embryol pmid:27516018
Wang Y et al. Protective Effect of ALA in Crushed Optic Nerve Cat Retinal Ganglion Cells Using a New Marker RBPMS. 2016 PLoS ONE pmid:27504635
Cacciatore I et al. Novel NSAID-Derived Drugs for the Potential Treatment of Alzheimer's Disease. 2016 Int J Mol Sci pmid:27376271
Ikuta N et al. Bioavailability of an R-α-Lipoic Acid/γ-Cyclodextrin Complex in Healthy Volunteers. 2016 Int J Mol Sci pmid:27314343
Li D et al. The Protective Effects of 5-Methoxytryptamine-α-lipoic Acid on Ionizing Radiation-Induced Hematopoietic Injury. 2016 Int J Mol Sci pmid:27314327
Santos V and Hirshfield I The Physiological and Molecular Characterization of a Small Colony Variant of Escherichia coli and Its Phenotypic Rescue. 2016 PLoS ONE pmid:27310825
Hwang S et al. Inhibitory Effects of α-Lipoic Acid on Oxidative Stress-Induced Adipogenesis in Orbital Fibroblasts From Patients With Graves Ophthalmopathy. 2016 Medicine (Baltimore) pmid:26765462
Wang J et al. Xenobiotics and loss of tolerance in primary biliary cholangitis. 2016 World J. Gastroenterol. pmid:26755880
Ströher E et al. Glutaredoxin S15 Is Involved in Fe-S Cluster Transfer in Mitochondria Influencing Lipoic Acid-Dependent Enzymes, Plant Growth, and Arsenic Tolerance in Arabidopsis. 2016 Plant Physiol. pmid:26672074
Sun B et al. Robust, active tumor-targeting and fast bioresponsive anticancer nanotherapeutics based on natural endogenous materials. 2016 Acta Biomater pmid:27576338