| MeSH term | MeSH ID | Detail |
|---|---|---|
| Hemolysis | D006461 | 131 associated lipids |
| Stomach Ulcer | D013276 | 75 associated lipids |
| Kidney Failure, Chronic | D007676 | 51 associated lipids |
| Diabetes Mellitus | D003920 | 90 associated lipids |
| Lead Poisoning | D007855 | 4 associated lipids |
| Hearing Loss, Sensorineural | D006319 | 8 associated lipids |
| Hypoxia | D000860 | 23 associated lipids |
| Arrhythmias, Cardiac | D001145 | 42 associated lipids |
| Acidosis, Lactic | D000140 | 8 associated lipids |
| Lung Neoplasms | D008175 | 171 associated lipids |
Lipoic acid
Lipoic acid is a lipid of Fatty Acyls (FA) class.
Cross Reference
There are no associated biomedical information in the current reference collection.
Current reference collection contains 18962 references associated with Lipoic acid in LipidPedia. Due to lack of full text of references or no associated biomedical terms are recognized in our current text-mining method, we cannot extract any biomedical terms related to diseases, pathways, locations, functions, genes, lipids, and animal models from the associated reference collection.
Users can download the reference list at the bottom of this page and read the reference manually to find out biomedical information.
Here are additional resources we collected from PubChem and MeSH for Lipoic acid
Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with Lipoic acid
PubChem Biomolecular Interactions and Pathways
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All references with Lipoic acid
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Arroll MA et al. | Nutritional interventions for the adjunctive treatment of schizophrenia: a brief review. | 2014 | Nutr J | pmid:25228271 |
| Byun E et al. | α-Lipoic acid inhibits Helicobacter pylori-induced oncogene expression and hyperproliferation by suppressing the activation of NADPH oxidase in gastric epithelial cells. | 2014 | Mediators Inflamm. | pmid:25210229 |
| Garcia Lde B et al. | Tissue response evaluation of the mucosa of the tympanic cavity of guinea pigs, when receiving biodegradable implant. | 2014 | Acta Cir Bras | pmid:25185050 |
| Yang Y et al. | Alpha-lipoic acid attenuates insulin resistance and improves glucose metabolism in high fat diet-fed mice. | 2014 | Acta Pharmacol. Sin. | pmid:25152027 |
| Gonzalez P et al. | Bimodal-hybrid heterocyclic amine targeting oxidative pathways and copper mis-regulation in Alzheimer's disease. | 2014 | Metallomics | pmid:25144522 |
| Yang Y et al. | Alpha-lipoic acid improves high-fat diet-induced hepatic steatosis by modulating the transcription factors SREBP-1, FoxO1 and Nrf2 via the SIRT1/LKB1/AMPK pathway. | 2014 | J. Nutr. Biochem. | pmid:25123628 |
| Letizia Mauro G et al. | α-Lipoic acid and superoxide dismutase in the management of chronic neck pain: a prospective randomized study. | 2014 | Drugs R D | pmid:24477618 |
| Todorovic SM and Jevtovic-Todorovic V | Redox regulation of neuronal voltage-gated calcium channels. | 2014 | Antioxid. Redox Signal. | pmid:24161125 |
| Ibrahim S et al. | Selective cytotoxicity and combined effects of camptothecin or paclitaxel with sodium-R-alpha lipoate on A549 human non-small cell lung cancer cells. | 2014 | Nutr Cancer | pmid:24063429 |
| Grasso S et al. | Effect of lipoic acid and α-glyceryl-phosphoryl-choline on astroglial cell proliferation and differentiation in primary culture. | 2014 | J. Neurosci. Res. | pmid:24166560 |
| Kim J et al. | Alpha-lipoic acid protects against cisplatin-induced ototoxicity via the regulation of MAPKs and proinflammatory cytokines. | 2014 | Biochem. Biophys. Res. Commun. | pmid:24796665 |
| Chen C et al. | 4-methylene-2-octyl-5-oxotetrahydrofuran-3-carboxylic acid (C75), an inhibitor of fatty-acid synthase, suppresses the mitochondrial fatty acid synthesis pathway and impairs mitochondrial function. | 2014 | J. Biol. Chem. | pmid:24784139 |
| Nikolai S et al. | R-α lipoic acid γ-cyclodextrin complex increases energy expenditure: a 4-month feeding study in mice. | 2014 | Nutrition | pmid:24377457 |
| Mehrotra A and Sandhir R | Mitochondrial cofactors in experimental Huntington's disease: behavioral, biochemical and histological evaluation. | 2014 | Behav. Brain Res. | pmid:24393741 |
| Andrade AS et al. | Alpha-lipoic acid restores tear production in an animal model of dry eye. | 2014 | Exp. Eye Res. | pmid:24394592 |
| Hahm JR et al. | Alpha-lipoic acid attenuates adipocyte differentiation and lipid accumulation in 3T3-L1 cells via AMPK-dependent autophagy. | 2014 | Life Sci. | pmid:24530288 |
| Biresaw G et al. | Synthesis and tribological investigation of lipoyl glycerides. | 2014 | J. Agric. Food Chem. | pmid:24576015 |
| Meng J et al. | [Effects of lipoic acid on cytokines and chemokines in astrocytes stimulated with lipopolysaccharide]. | 2014 | Xi Bao Yu Fen Zi Mian Yi Xue Za Zhi | pmid:24721398 |
| Dwivedi N et al. | Alpha-lipoic acid protects oxidative stress, changes in cholinergic system and tissue histopathology during co-exposure to arsenic-dichlorvos in rats. | 2014 | Environ. Toxicol. Pharmacol. | pmid:24291368 |
| Gras D et al. | GLUT1 deficiency syndrome: an update. | 2014 | Rev. Neurol. (Paris) | pmid:24269118 |
| Zygmunt M et al. | Anti-inflammatory activity of lipoic acid in mice peritonitis model. | 2013 Sep-Oct | Acta Pol Pharm | pmid:24147369 |
| Koriyama Y et al. | Anti-inflammatory effects of lipoic acid through inhibition of GSK-3β in lipopolysaccharide-induced BV-2 microglial cells. | 2013 Sep-Oct | Neurosci. Res. | pmid:23892131 |
| Sayın M et al. | The dose-dependent neuroprotective effect of alpha-lipoic acid in experimental spinal cord injury. | 2013 Jul-Aug | Neurol. Neurochir. Pol. | pmid:23986424 |
| Durand M and Mach N | [Alpha lipoic acid and its antioxidant against cancer and diseases of central sensitization]. | 2013 Jul-Aug | Nutr Hosp | pmid:23889618 |
| Haber A et al. | Combating diabetes complications by 1-Fe, a corrole-based catalytic antioxidant. | 2013 Jul-Aug | J. Diabetes Complicat. | pmid:23602197 |
| Mitkov MD et al. | Effect of transdermal testosterone or alpha-lipoic acid on erectile dysfunction and quality of life in patients with type 2 diabetes mellitus. | 2013 Jan-Mar | Folia Med (Plovdiv) | pmid:23905488 |
| Nebbioso M et al. | Mechanisms of ocular neuroprotection by antioxidant molecules in animal models. | 2013 Jan-Mar | J. Biol. Regul. Homeost. Agents | pmid:23489699 |
| Leu JG et al. | Epigallocatechin-3-gallate combined with alpha lipoic acid attenuates high glucose-induced receptor for advanced glycation end products (RAGE) expression in human embryonic kidney cells. | 2013 Apr-Jun | An. Acad. Bras. Cienc. | pmid:23780308 |
| Jaiswal JK and Simon SM | Belling the cat--tagging live cells with quantum dots. | 2013 | Clin. Chem. | pmid:23358412 |
| Micili SC et al. | The effect of lipoic acid on wound healing in a full thickness uterine injury model in rats. | 2013 | J. Mol. Histol. | pmid:23371355 |
| Kim HS et al. | α-Lipoic acid attenuates coxsackievirus B3-induced ectopic calcification in heart, pancreas, and lung. | 2013 | Biochem. Biophys. Res. Commun. | pmid:23357417 |
| Mansoor S et al. | Protective effects of lipoic acid on chrysene-induced toxicity on Müller cells in vitro. | 2013 | Mol. Vis. | pmid:23335848 |
| Kapoor S | Hepato-protective effects of alpha lipoic acid besides its role in preventing fatty liver disease. | 2013 | Liver Int. | pmid:23151269 |
| Posner MG et al. | Post-translational modification in the archaea: structural characterization of multi-enzyme complex lipoylation. | 2013 | Biochem. J. | pmid:23116157 |
| Zhu YY et al. | A novel andrographolide derivative AL-1 exerts its cytotoxicity on K562 cells through a ROS-dependent mechanism. | 2013 | Proteomics | pmid:23161516 |
| Jayakar SS and Singhal RS | Kinetic modeling and scale up of lipoic acid (LA) production from Saccharomyces cerevisiae in a stirred tank bioreactor. | 2013 | Bioprocess Biosyst Eng | pmid:23178984 |
| Ferrer-Cortès X et al. | Protein expression profiles in patients carrying NFU1 mutations. Contribution to the pathophysiology of the disease. | 2013 | J. Inherit. Metab. Dis. | pmid:23179554 |
| Zembron-Lacny A et al. | Physical activity and alpha-lipoic acid modulate inflammatory response through changes in thiol redox status. | 2013 | J. Physiol. Biochem. | pmid:23180154 |
| Ton T et al. | Dose dependent morphological effects of alpha lipoic acid on vasospastic femoral artery in rats. | 2013 | Turk Neurosurg | pmid:23546899 |
| Singh V et al. | Chemistry of conjugation to gold nanoparticles affects G-protein activity differently. | 2013 | J Nanobiotechnology | pmid:23510390 |
| Okuyan M et al. | Electrophysiological evidence for the anticonvulsant effect of alpha-lipoic acid via indirect antioxidant properties in BALB/c mice. | 2013 | Neurol. Res. | pmid:23562187 |
| Jiang S et al. | α-Lipoic acid attenuates LPS-induced cardiac dysfunction through a PI3K/Akt-dependent mechanism. | 2013 | Int. Immunopharmacol. | pmid:23562296 |
| GorÄ…ca A et al. | Effects of lipoic acid on spleen oxidative stress after LPS administration. | 2013 | Pharmacol Rep | pmid:23563036 |
| Abadi A et al. | Supplementation with α-lipoic acid, CoQ10, and vitamin E augments running performance and mitochondrial function in female mice. | 2013 | PLoS ONE | pmid:23565271 |
| Papadopoulou AA et al. | Enzymatic hybridization of α-lipoic acid with bioactive compounds in ionic solvents. | 2013 | Bioresour. Technol. | pmid:23567667 |
| Wang KC et al. | α-Lipoic acid enhances endogenous peroxisome-proliferator-activated receptor-γ to ameliorate experimental autoimmune encephalomyelitis in mice. | 2013 | Clin. Sci. | pmid:23550596 |
| Michikoshi H et al. | α-Lipoic acid-induced inhibition of proliferation and met phosphorylation in human non-small cell lung cancer cells. | 2013 | Cancer Lett. | pmid:23507559 |
| Lobato RO et al. | The role of lipoic acid in the protection against of metallic pollutant effects in the shrimp Litopenaeus vannamei (Crustacea, Decapoda). | 2013 | Comp. Biochem. Physiol., Part A Mol. Integr. Physiol. | pmid:23507566 |
| Wu L et al. | Intracellular release of doxorubicin from core-crosslinked polypeptide micelles triggered by both pH and reduction conditions. | 2013 | Biomaterials | pmid:23570719 |
| Yan GR et al. | Protective effects of andrographolide analogue AL-1 on ROS-induced RIN-mβ cell death by inducing ROS generation. | 2013 | PLoS ONE | pmid:23750203 |
| Rokicki W et al. | Effect of selected dietary compounds on extracellular superoxide dismutase in the vitreous of chinchillas. | 2013 | Ophthalmic Res. | pmid:23751285 |
| Spreafico A et al. | Antioxidants inhibit SAA formation and pro-inflammatory cytokine release in a human cell model of alkaptonuria. | 2013 | Rheumatology (Oxford) | pmid:23704321 |
| Capasso I et al. | Combination of inositol and alpha lipoic acid in metabolic syndrome-affected women: a randomized placebo-controlled trial. | 2013 | Trials | pmid:23981814 |
| Shapira R et al. | Multifunctional cyclic D,L-α-peptide architectures stimulate non-insulin dependent glucose uptake in skeletal muscle cells and protect them against oxidative stress. | 2013 | J. Med. Chem. | pmid:23984871 |
| Redmer J et al. | Targeting diabetes: the benefits of an integrative approach. | 2013 | J Fam Pract | pmid:23957026 |
| Zhao L et al. | Oxidative stress impairs IKCa- and SKCa-mediated vasodilatation in mesenteric arteries from diabetic rats. | 2013 | Nan Fang Yi Ke Da Xue Xue Bao | pmid:23895829 |
| Brennan BP et al. | A placebo-controlled trial of acetyl-L-carnitine and α-lipoic acid in the treatment of bipolar depression. | 2013 | J Clin Psychopharmacol | pmid:23948785 |
| Manolescu BN et al. | Effect of the nutritional supplement ALAnerv® on the serum PON1 activity in post-acute stroke patients. | 2013 | Pharmacol Rep | pmid:23950599 |
| Wongmekiat O et al. | Alpha-lipoic acid attenuates renal injury in rats with obstructive nephropathy. | 2013 | Biomed Res Int | pmid:24288661 |
| Bryk R et al. | Lipoamide channel-binding sulfonamides selectively inhibit mycobacterial lipoamide dehydrogenase. | 2013 | Biochemistry | pmid:24251446 |
| Feng B et al. | The protective effects of α-lipoic acid on kidneys in type 2 diabetic Goto-Kakisaki rats via reducing oxidative stress. | 2013 | Int J Mol Sci | pmid:23531536 |
| Deslauriers J et al. | α-Lipoic acid interaction with dopamine D2 receptor-dependent activation of the Akt/GSK-3β signaling pathway induced by antipsychotics: potential relevance for the treatment of schizophrenia. | 2013 | J. Mol. Neurosci. | pmid:22975849 |
| Hermes FA and Cronan JE | The role of the Saccharomyces cerevisiae lipoate protein ligase homologue, Lip3, in lipoic acid synthesis. | 2013 | Yeast | pmid:23960015 |
| Soreze Y et al. | Mutations in human lipoyltransferase gene LIPT1 cause a Leigh disease with secondary deficiency for pyruvate and alpha-ketoglutarate dehydrogenase. | 2013 | Orphanet J Rare Dis | pmid:24341803 |
| Schwartz L et al. | Tumor regression with a combination of drugs interfering with the tumor metabolism: efficacy of hydroxycitrate, lipoic acid and capsaicin. | 2013 | Invest New Drugs | pmid:22797854 |
| Ide T et al. | Combined effect of sesamin and α-lipoic acid on hepatic fatty acid metabolism in rats. | 2013 | Eur J Nutr | pmid:22752262 |
| Tomassoni D et al. | Neuroprotective activity of thioctic acid in central nervous system lesions consequent to peripheral nerve injury. | 2013 | Biomed Res Int | pmid:24527432 |
| Arshad MS et al. | Wheat germ oil enrichment in broiler feed with α-lipoic acid to enhance the antioxidant potential and lipid stability of meat. | 2013 | Lipids Health Dis | pmid:24499336 |
| Prieto-Hontoria PL et al. | Effects of lipoic acid on AMPK and adiponectin in adipose tissue of low- and high-fat-fed rats. | 2013 | Eur J Nutr | pmid:22664981 |
| Tisato V et al. | Inhibitory effect of natural anti-inflammatory compounds on cytokines released by chronic venous disease patient-derived endothelial cells. | 2013 | Mediators Inflamm. | pmid:24489443 |
| Bhadri N et al. | Amelioration of behavioural, biochemical, and neurophysiological deficits by combination of monosodium glutamate with resveratrol/alpha-lipoic acid/coenzyme Q10 in rat model of cisplatin-induced peripheral neuropathy. | 2013 | ScientificWorldJournal | pmid:24489506 |
| Noori N et al. | Effects of combined lipoic acid and pyridoxine on albuminuria, advanced glycation end-products, and blood pressure in diabetic nephropathy. | 2013 | Int J Vitam Nutr Res | pmid:24491880 |
| Maksymiak M et al. | Structural characterization of biocompatible lipoic acid-oligo-(3-hydroxybutyrate) conjugates by electrospray ionization mass spectrometry. | 2013 | Rapid Commun. Mass Spectrom. | pmid:23495024 |
| Cao X et al. | Alpha-lipoic acid protects cardiomyocytes against hypoxia/reoxygenation injury by inhibiting autophagy. | 2013 | Biochem. Biophys. Res. Commun. | pmid:24216106 |
| Moreno JA and Hong E | A single oral dose of fructose induces some features of metabolic syndrome in rats: role of oxidative stress. | 2013 | Nutr Metab Cardiovasc Dis | pmid:22386006 |
| Manning PJ et al. | The effect of lipoic acid and vitamin E therapies in individuals with the metabolic syndrome. | 2013 | Nutr Metab Cardiovasc Dis | pmid:22402059 |
| Fogarty MC et al. | Effects of α-lipoic acid on mtDNA damage after isolated muscle contractions. | 2013 | Med Sci Sports Exerc | pmid:23470303 |
| Abdel-Zaher AO et al. | Role of oxidative stress and inducible nitric oxide synthase in morphine-induced tolerance and dependence in mice. Effect of alpha-lipoic acid. | 2013 | Behav. Brain Res. | pmid:23470902 |
| Jalali-Nadoushan M and Roghani M | Alpha-lipoic acid protects against 6-hydroxydopamine-induced neurotoxicity in a rat model of hemi-parkinsonism. | 2013 | Brain Res. | pmid:23415934 |
| Georgakouli K et al. | Α-lipoic acid supplementation up-regulates antioxidant capacity in adults with G6PD deficiency. | 2013 | Food Chem. Toxicol. | pmid:23416142 |
| Sozio P et al. | Memantine-sulfur containing antioxidant conjugates as potential prodrugs to improve the treatment of Alzheimer's disease. | 2013 | Eur J Pharm Sci | pmid:23454012 |
| Deng C et al. | α-Lipoic acid reduces infarct size and preserves cardiac function in rat myocardial ischemia/reperfusion injury through activation of PI3K/Akt/Nrf2 pathway. | 2013 | PLoS ONE | pmid:23505496 |
| Longaray-Garcia M et al. | Modulation of antioxidant and detoxifying capacity in fish Cyprinus carpio (Cyprinidae) after treatment with nanocapsules containing lipoic acid. | 2013 | Comp. Biochem. Physiol., Part A Mol. Integr. Physiol. | pmid:23402748 |
| Kumazaki M et al. | α-Lipoic acid protects against arsenic trioxide-induced acute QT prolongation in anesthetized guinea pigs. | 2013 | Eur. J. Pharmacol. | pmid:23474023 |
| Trevisan G et al. | Novel therapeutic strategy to prevent chemotherapy-induced persistent sensory neuropathy by TRPA1 blockade. | 2013 | Cancer Res. | pmid:23477783 |
| Nebbioso M et al. | Lipoic acid in animal models and clinical use in diabetic retinopathy. | 2013 | Expert Opin Pharmacother | pmid:23790257 |
| Trivedi PP and Jena GB | Role of α-lipoic acid in dextran sulfate sodium-induced ulcerative colitis in mice: studies on inflammation, oxidative stress, DNA damage and fibrosis. | 2013 | Food Chem. Toxicol. | pmid:23793040 |
| Kim YS et al. | Cytoprotective effect of alpha-lipoic acid on paraquat-exposed human bronchial epithelial cells via activation of nuclear factor erythroid related factor-2 pathway. | 2013 | Biol. Pharm. Bull. | pmid:23649336 |
| Cicek M et al. | Use of alpha-lipoic acid in prevention of contrast-induced nephropathy in diabetic patients. | 2013 | Ren Fail | pmid:23650950 |
| Tian YF et al. | Lipoic acid suppresses portal endotoxemia-induced steatohepatitis and pancreatic inflammation in rats. | 2013 | World J. Gastroenterol. | pmid:23687413 |
| Ibrahimpasic K | Alpha lipoic acid and glycaemic control in diabetic neuropathies at type 2 diabetes treatment. | 2013 | Med Arch | pmid:23678828 |
| Mérida S et al. | Lipoic acid lessens Th1-mediated inflammation in lipopolysaccharide-induced uveitis reducing selectively Th1 lymphocytes-related cytokines release. | 2013 | Free Radic. Res. | pmid:23678888 |
| Broskova Z et al. | Ischemia-reperfusion injury of the isolated diabetic rat heart: effect of the antioxidant stobadine. | 2013 | Gen. Physiol. Biophys. | pmid:23682019 |
| Al-Rasheed NM et al. | Adverse cardiac responses to alpha-lipoic acid in a rat-diabetic model: possible mechanisms? | 2013 | J. Physiol. Biochem. | pmid:23595962 |
| Yoo TH et al. | α-Lipoic acid prevents p53 degradation in colon cancer cells by blocking NF-κB induction of RPS6KA4. | 2013 | Anticancer Drugs | pmid:23599020 |
| Xu J et al. | Flaxseed oil and alpha-lipoic acid combination ameliorates hepatic oxidative stress and lipid accumulation in comparison to lard. | 2013 | Lipids Health Dis | pmid:23634883 |
| Lee SM et al. | Surface-engineered nanomaterials as X-ray absorbing adjuvant agents for Auger-mediated chemo-radiation. | 2013 | Nanoscale | pmid:23657262 |
| Koizumi R et al. | Interaction of 9,10-phenanthraquinone with dithiol causes oxidative modification of Cu,Zn-superoxide dismutase (SOD) through redox cycling. | 2013 | J Toxicol Sci | pmid:23665930 |
| Volchegorskii IA et al. | Cerebroprotective effects of emoxipin, reamberin, and mexidol in alloxan diabetes. | 2013 | Bull. Exp. Biol. Med. | pmid:23667872 |
| Scalia S et al. | Comparative evaluation of different co-antioxidants on the photochemical- and functional-stability of epigallocatechin-3-gallate in topical creams exposed to simulated sunlight. | 2013 | Molecules | pmid:23292326 |