| MeSH term | MeSH ID | Detail |
|---|---|---|
| Hemolysis | D006461 | 131 associated lipids |
| Stomach Ulcer | D013276 | 75 associated lipids |
| Kidney Failure, Chronic | D007676 | 51 associated lipids |
| Diabetes Mellitus | D003920 | 90 associated lipids |
| Lead Poisoning | D007855 | 4 associated lipids |
| Hearing Loss, Sensorineural | D006319 | 8 associated lipids |
| Hypoxia | D000860 | 23 associated lipids |
| Arrhythmias, Cardiac | D001145 | 42 associated lipids |
| Acidosis, Lactic | D000140 | 8 associated lipids |
| Lung Neoplasms | D008175 | 171 associated lipids |
Lipoic acid
Lipoic acid is a lipid of Fatty Acyls (FA) class.
Cross Reference
There are no associated biomedical information in the current reference collection.
Current reference collection contains 18962 references associated with Lipoic acid in LipidPedia. Due to lack of full text of references or no associated biomedical terms are recognized in our current text-mining method, we cannot extract any biomedical terms related to diseases, pathways, locations, functions, genes, lipids, and animal models from the associated reference collection.
Users can download the reference list at the bottom of this page and read the reference manually to find out biomedical information.
Here are additional resources we collected from PubChem and MeSH for Lipoic acid
Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with Lipoic acid
PubChem Biomolecular Interactions and Pathways
NCBI Entrez Crosslinks
All references with Lipoic acid
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Leung PS et al. | Environment and primary biliary cirrhosis: electrophilic drugs and the induction of AMA. | 2013 | J. Autoimmun. | pmid:23352659 |
| Prieto-Hontoria PL et al. | Lipoic acid inhibits adiponectin production in 3T3-L1 adipocytes. | 2013 | J. Physiol. Biochem. | pmid:23307774 |
| Dinić S et al. | Decreased O-GlcNAcylation of the key proteins in kinase and redox signalling pathways is a novel mechanism of the beneficial effect of α-lipoic acid in diabetic liver. | 2013 | Br. J. Nutr. | pmid:23312093 |
| Sudheesh NP et al. | Hepatoprotective effects of DL-α-lipoic acid and α-Tocopherol through amelioration of the mitochondrial oxidative stress in acetaminophen challenged rats. | 2013 | Toxicol. Mech. Methods | pmid:23343353 |
| Jaiswal JK and Simon SM | Belling the cat--tagging live cells with quantum dots. | 2013 | Clin. Chem. | pmid:23358412 |
| Micili SC et al. | The effect of lipoic acid on wound healing in a full thickness uterine injury model in rats. | 2013 | J. Mol. Histol. | pmid:23371355 |
| Kim HS et al. | α-Lipoic acid attenuates coxsackievirus B3-induced ectopic calcification in heart, pancreas, and lung. | 2013 | Biochem. Biophys. Res. Commun. | pmid:23357417 |
| Mansoor S et al. | Protective effects of lipoic acid on chrysene-induced toxicity on Müller cells in vitro. | 2013 | Mol. Vis. | pmid:23335848 |
| Kapoor S | Hepato-protective effects of alpha lipoic acid besides its role in preventing fatty liver disease. | 2013 | Liver Int. | pmid:23151269 |
| Mıcılı SC et al. | Effects of lipoic acid in an experimentally induced hypertensive and diabetic rat model. | 2013 | Clin. Exp. Hypertens. | pmid:23072377 |
| Külkamp-Guerreiro IC et al. | Influence of nanoencapsulation on the sensory properties of cosmetic formulations containing lipoic acid. | 2013 | Int J Cosmet Sci | pmid:23075068 |
| Baky NA et al. | Induction of inflammation, DNA damage and apoptosis in rat heart after oral exposure to zinc oxide nanoparticles and the cardioprotective role of α-lipoic acid and vitamin E. | 2013 | Drug Res (Stuttg) | pmid:23532625 |
| Ong SL et al. | The effect of alpha-lipoic acid on mitochondrial superoxide and glucocorticoid-induced hypertension. | 2013 | Oxid Med Cell Longev | pmid:23533693 |
| Zhou L et al. | α-Lipoic acid ameliorates mitochondrial impairment and reverses apoptosis in FABP3-overexpressing embryonic cancer cells. | 2013 | J. Bioenerg. Biomembr. | pmid:23536161 |
| Silva MC et al. | Augmentation therapy with alpha-lipoic acid and desvenlafaxine: a future target for treatment of depression? | 2013 | Naunyn Schmiedebergs Arch. Pharmacol. | pmid:23584634 |
| Hiratsuka T et al. | DHL‑TauZnNa, a newly synthesized α-lipoic acid derivative, induces autophagy in human colorectal cancer cells. | 2013 | Oncol. Rep. | pmid:23588820 |
| Sahli R et al. | Switching on/off the chemisorption of thioctic-based self-assembled monolayers on gold by applying a moderate cathodic/anodic potential. | 2013 | Langmuir | pmid:23540684 |
| Ton T et al. | Dose dependent morphological effects of alpha lipoic acid on vasospastic femoral artery in rats. | 2013 | Turk Neurosurg | pmid:23546899 |
| Singh V et al. | Chemistry of conjugation to gold nanoparticles affects G-protein activity differently. | 2013 | J Nanobiotechnology | pmid:23510390 |
| Okuyan M et al. | Electrophysiological evidence for the anticonvulsant effect of alpha-lipoic acid via indirect antioxidant properties in BALB/c mice. | 2013 | Neurol. Res. | pmid:23562187 |
| Jiang S et al. | α-Lipoic acid attenuates LPS-induced cardiac dysfunction through a PI3K/Akt-dependent mechanism. | 2013 | Int. Immunopharmacol. | pmid:23562296 |
| GorÄ…ca A et al. | Effects of lipoic acid on spleen oxidative stress after LPS administration. | 2013 | Pharmacol Rep | pmid:23563036 |
| Abadi A et al. | Supplementation with α-lipoic acid, CoQ10, and vitamin E augments running performance and mitochondrial function in female mice. | 2013 | PLoS ONE | pmid:23565271 |
| Papadopoulou AA et al. | Enzymatic hybridization of α-lipoic acid with bioactive compounds in ionic solvents. | 2013 | Bioresour. Technol. | pmid:23567667 |
| Wang KC et al. | α-Lipoic acid enhances endogenous peroxisome-proliferator-activated receptor-γ to ameliorate experimental autoimmune encephalomyelitis in mice. | 2013 | Clin. Sci. | pmid:23550596 |
| Ishiki M et al. | Impact of divergent effects of astaxanthin on insulin signaling in L6 cells. | 2013 | Endocrinology | pmid:23715867 |
| Rhoads RP et al. | Nutritional interventions to alleviate the negative consequences of heat stress. | 2013 | Adv Nutr | pmid:23674792 |
| Jin HB et al. | Lipoic acid attenuates the expression of adhesion molecules by increasing endothelial nitric-oxide synthase activity. | 2013 | Mol. Biol. Rep. | pmid:23054010 |
| Karatug A and Bolkent S | The potential role of combined antioxidant treatment on pancreas of STZ-diabetic mice. | 2013 | Exp. Toxicol. Pathol. | pmid:21968281 |
| Zhan N et al. | Multidentate zwitterionic ligands provide compact and highly biocompatible quantum dots. | 2013 | J. Am. Chem. Soc. | pmid:24003892 |
| VolchegorskiÄ IA et al. | [Experimental study of 3-oxypiridine and succinic acid derivates antidepressant activity in mice]. | 2013 | Eksp Klin Farmakol | pmid:24006608 |
| Miao Y et al. | α-Lipoic acid attenuates obesity-associated hippocampal neuroinflammation and increases the levels of brain-derived neurotrophic factor in ovariectomized rats fed a high-fat diet. | 2013 | Int. J. Mol. Med. | pmid:24008266 |
| Capasso I et al. | Combination of inositol and alpha lipoic acid in metabolic syndrome-affected women: a randomized placebo-controlled trial. | 2013 | Trials | pmid:23981814 |
| Shapira R et al. | Multifunctional cyclic D,L-α-peptide architectures stimulate non-insulin dependent glucose uptake in skeletal muscle cells and protect them against oxidative stress. | 2013 | J. Med. Chem. | pmid:23984871 |
| Redmer J et al. | Targeting diabetes: the benefits of an integrative approach. | 2013 | J Fam Pract | pmid:23957026 |
| Zhao L et al. | Oxidative stress impairs IKCa- and SKCa-mediated vasodilatation in mesenteric arteries from diabetic rats. | 2013 | Nan Fang Yi Ke Da Xue Xue Bao | pmid:23895829 |
| Brennan BP et al. | A placebo-controlled trial of acetyl-L-carnitine and α-lipoic acid in the treatment of bipolar depression. | 2013 | J Clin Psychopharmacol | pmid:23948785 |
| Manolescu BN et al. | Effect of the nutritional supplement ALAnerv® on the serum PON1 activity in post-acute stroke patients. | 2013 | Pharmacol Rep | pmid:23950599 |
| Zhivolupov SA et al. | [Metabolic therapy in neurology]. | 2013 | Zh Nevrol Psikhiatr Im S S Korsakova | pmid:23994919 |
| Battisti E et al. | Alpha lipoic acid and superoxide dismutase in the treatment of chronic low back pain. | 2013 | Eur J Phys Rehabil Med | pmid:23860422 |
| Wijayanti HB et al. | Reduction of aggregation of β-lactoglobulin during heating by dihydrolipoic acid. | 2013 | J. Dairy Res. | pmid:23866304 |
| Dudek M et al. | Are anti-inflammatory properties of lipoic acid associated with the formation of hydrogen sulfide? | 2013 | Pharmacol Rep | pmid:24145097 |
| Steele ML et al. | Effect of Nrf2 activators on release of glutathione, cysteinylglycine and homocysteine by human U373 astroglial cells. | 2013 | Redox Biol | pmid:24191238 |
| Usta J et al. | Fragrance chemicals lyral and lilial decrease viability of HaCat cells' by increasing free radical production and lowering intracellular ATP level: protection by antioxidants. | 2013 | Toxicol In Vitro | pmid:22940465 |
| Lu C et al. | Synthesis of lipoic acid-peptide conjugates and their effect on collagen and melanogenesis. | 2013 | Eur J Med Chem | pmid:24090916 |
| Hardas SS et al. | Oxidative modification of lipoic acid by HNE in Alzheimer disease brain. | 2013 | Redox Biol | pmid:24024140 |
| Külkamp-Guerreiro IC et al. | Evaluation of lipoic acid topical application on rats skin wound healing. | 2013 | Acta Cir Bras | pmid:24114299 |
| Parveen R et al. | Selective deposition of dietary α-lipoic acid in mitochondrial fraction and its synergistic effect with α-tocoperhol acetate on broiler meat oxidative stability. | 2013 | Lipids Health Dis | pmid:23617815 |
| McLain AL et al. | Glutathionylation of α-ketoglutarate dehydrogenase: the chemical nature and relative susceptibility of the cofactor lipoic acid to modification. | 2013 | Free Radic. Biol. Med. | pmid:23567190 |
| Feng B et al. | The protective effects of α-lipoic acid on kidneys in type 2 diabetic Goto-Kakisaki rats via reducing oxidative stress. | 2013 | Int J Mol Sci | pmid:23531536 |
| Chan WH et al. | Impact of dihydrolipoic acid on mouse embryonic stem cells and related regulatory mechanisms. | 2013 | Environ. Toxicol. | pmid:21462292 |
| Carmine A et al. | Comparison of lipoic and asparagusic acid for surface-initiated disulfide-exchange polymerization. | 2013 | Chemistry | pmid:23893874 |
| Soreze Y et al. | Mutations in human lipoyltransferase gene LIPT1 cause a Leigh disease with secondary deficiency for pyruvate and alpha-ketoglutarate dehydrogenase. | 2013 | Orphanet J Rare Dis | pmid:24341803 |
| Schwartz L et al. | Tumor regression with a combination of drugs interfering with the tumor metabolism: efficacy of hydroxycitrate, lipoic acid and capsaicin. | 2013 | Invest New Drugs | pmid:22797854 |
| Ide T et al. | Combined effect of sesamin and α-lipoic acid on hepatic fatty acid metabolism in rats. | 2013 | Eur J Nutr | pmid:22752262 |
| Tomassoni D et al. | Neuroprotective activity of thioctic acid in central nervous system lesions consequent to peripheral nerve injury. | 2013 | Biomed Res Int | pmid:24527432 |
| Arshad MS et al. | Wheat germ oil enrichment in broiler feed with α-lipoic acid to enhance the antioxidant potential and lipid stability of meat. | 2013 | Lipids Health Dis | pmid:24499336 |
| Tisato V et al. | Inhibitory effect of natural anti-inflammatory compounds on cytokines released by chronic venous disease patient-derived endothelial cells. | 2013 | Mediators Inflamm. | pmid:24489443 |
| Akman S et al. | Therapeutic effects of alpha lipoic acid and vitamin C on alveolar bone resorption after experimental periodontitis in rats: a biochemical, histochemical, and stereologic study. | 2013 | J. Periodontol. | pmid:22702517 |
| Pashaj A et al. | Characterization of genome-wide transcriptional changes in liver and adipose tissues of ZDF (fa/fa) rats fed R-α-lipoic acid by next-generation sequencing. | 2013 | Physiol. Genomics | pmid:24104204 |
| Polat B et al. | The effect of alpha-lipoic acid in ovariectomy and inflammation-mediated osteoporosis on the skeletal status of rat bone. | 2013 | Eur. J. Pharmacol. | pmid:23911880 |
| Koh G et al. | Alpha-lipoic acid treatment reverses 2-deoxy-D-ribose-induced oxidative damage and suppression of insulin expression in pancreatic beta-cells. | 2013 | Biol. Pharm. Bull. | pmid:23912745 |
| Arshad MS et al. | Wheat germ oil and α-lipoic acid predominantly improve the lipid profile of broiler meat. | 2013 | J. Agric. Food Chem. | pmid:24191686 |
| Cao X et al. | Alpha-lipoic acid protects cardiomyocytes against hypoxia/reoxygenation injury by inhibiting autophagy. | 2013 | Biochem. Biophys. Res. Commun. | pmid:24216106 |
| Moreno JA and Hong E | A single oral dose of fructose induces some features of metabolic syndrome in rats: role of oxidative stress. | 2013 | Nutr Metab Cardiovasc Dis | pmid:22386006 |
| Manning PJ et al. | The effect of lipoic acid and vitamin E therapies in individuals with the metabolic syndrome. | 2013 | Nutr Metab Cardiovasc Dis | pmid:22402059 |
| Kumar P and Dwivedi N | Proline catalyzed α-aminoxylation reaction in the synthesis of biologically active compounds. | 2013 | Acc. Chem. Res. | pmid:23148510 |
| Falkard B et al. | A key role for lipoic acid synthesis during Plasmodium liver stage development. | 2013 | Cell. Microbiol. | pmid:23490300 |
| Zara S et al. | Ibuprofen and lipoic acid conjugate neuroprotective activity is mediated by Ngb/Akt intracellular signaling pathway in Alzheimer's disease rat model. | 2013 | Gerontology | pmid:23428737 |
| Astiz M et al. | Pesticide-induced decrease in rat testicular steroidogenesis is differentially prevented by lipoate and tocopherol. | 2013 | Ecotoxicol. Environ. Saf. | pmid:23465731 |
| Picotti F et al. | Hyaluronic acid lipoate: synthesis and physicochemical properties. | 2013 | Carbohydr Polym | pmid:23465930 |
| Prezzavento O et al. | Design and synthesis of new bifunctional sigma-1 selective ligands with antioxidant activity. | 2013 | J. Med. Chem. | pmid:23470245 |
| Fogarty MC et al. | Effects of α-lipoic acid on mtDNA damage after isolated muscle contractions. | 2013 | Med Sci Sports Exerc | pmid:23470303 |
| Abdel-Zaher AO et al. | Role of oxidative stress and inducible nitric oxide synthase in morphine-induced tolerance and dependence in mice. Effect of alpha-lipoic acid. | 2013 | Behav. Brain Res. | pmid:23470902 |
| Jalali-Nadoushan M and Roghani M | Alpha-lipoic acid protects against 6-hydroxydopamine-induced neurotoxicity in a rat model of hemi-parkinsonism. | 2013 | Brain Res. | pmid:23415934 |
| Georgakouli K et al. | Α-lipoic acid supplementation up-regulates antioxidant capacity in adults with G6PD deficiency. | 2013 | Food Chem. Toxicol. | pmid:23416142 |
| Sozio P et al. | Memantine-sulfur containing antioxidant conjugates as potential prodrugs to improve the treatment of Alzheimer's disease. | 2013 | Eur J Pharm Sci | pmid:23454012 |
| Deng C et al. | α-Lipoic acid reduces infarct size and preserves cardiac function in rat myocardial ischemia/reperfusion injury through activation of PI3K/Akt/Nrf2 pathway. | 2013 | PLoS ONE | pmid:23505496 |
| Longaray-Garcia M et al. | Modulation of antioxidant and detoxifying capacity in fish Cyprinus carpio (Cyprinidae) after treatment with nanocapsules containing lipoic acid. | 2013 | Comp. Biochem. Physiol., Part A Mol. Integr. Physiol. | pmid:23402748 |
| Satsu H et al. | A sphingosine 1-phosphate receptor 2 selective allosteric agonist. | 2013 | Bioorg. Med. Chem. | pmid:23849205 |
| Lakhtin IuV | Comparative evaluation of short- and long-term treatment of periodontitis with alpha-lipoic acid. | 2013 | Georgian Med News | pmid:23787501 |
| Kumar S et al. | Lipoic acid prevents Cr(6+) induced cell transformation and the associated genomic dysregulation. | 2013 | Environ. Toxicol. Pharmacol. | pmid:23608068 |
| Sokołowska M et al. | The effect of lipoic acid on cyanate toxicity in different structures of the rat brain. | 2013 | Neurotox Res | pmid:23625581 |
| Li DW et al. | α-lipoic acid protects dopaminergic neurons against MPP+-induced apoptosis by attenuating reactive oxygen species formation. | 2013 | Int. J. Mol. Med. | pmid:23615851 |
| Kwiecień B et al. | In vivo anti-inflammatory activity of lipoic acid derivatives in mice. | 2013 | Postepy Hig Med Dosw (Online) | pmid:23619233 |
| Cichewicz A et al. | Cutaneous delivery of α-tocopherol and lipoic acid using microemulsions: influence of composition and charge. | 2013 | J. Pharm. Pharmacol. | pmid:23647675 |
| Schloss JM et al. | Nutraceuticals and chemotherapy induced peripheral neuropathy (CIPN): a systematic review. | 2013 | Clin Nutr | pmid:23647723 |
| Kim YS et al. | Cytoprotective effect of alpha-lipoic acid on paraquat-exposed human bronchial epithelial cells via activation of nuclear factor erythroid related factor-2 pathway. | 2013 | Biol. Pharm. Bull. | pmid:23649336 |
| Cicek M et al. | Use of alpha-lipoic acid in prevention of contrast-induced nephropathy in diabetic patients. | 2013 | Ren Fail | pmid:23650950 |
| Tian YF et al. | Lipoic acid suppresses portal endotoxemia-induced steatohepatitis and pancreatic inflammation in rats. | 2013 | World J. Gastroenterol. | pmid:23687413 |
| Ibrahimpasic K | Alpha lipoic acid and glycaemic control in diabetic neuropathies at type 2 diabetes treatment. | 2013 | Med Arch | pmid:23678828 |
| Mérida S et al. | Lipoic acid lessens Th1-mediated inflammation in lipopolysaccharide-induced uveitis reducing selectively Th1 lymphocytes-related cytokines release. | 2013 | Free Radic. Res. | pmid:23678888 |
| Broskova Z et al. | Ischemia-reperfusion injury of the isolated diabetic rat heart: effect of the antioxidant stobadine. | 2013 | Gen. Physiol. Biophys. | pmid:23682019 |
| Al-Rasheed NM et al. | Adverse cardiac responses to alpha-lipoic acid in a rat-diabetic model: possible mechanisms? | 2013 | J. Physiol. Biochem. | pmid:23595962 |
| Yoo TH et al. | α-Lipoic acid prevents p53 degradation in colon cancer cells by blocking NF-κB induction of RPS6KA4. | 2013 | Anticancer Drugs | pmid:23599020 |
| Xu J et al. | Flaxseed oil and alpha-lipoic acid combination ameliorates hepatic oxidative stress and lipid accumulation in comparison to lard. | 2013 | Lipids Health Dis | pmid:23634883 |
| Kursu VA et al. | Defects in mitochondrial fatty acid synthesis result in failure of multiple aspects of mitochondrial biogenesis in Saccharomyces cerevisiae. | 2013 | Mol. Microbiol. | pmid:24102902 |
| Moraes TB et al. | Role of catalase and superoxide dismutase activities on oxidative stress in the brain of a phenylketonuria animal model and the effect of lipoic acid. | 2013 | Cell. Mol. Neurobiol. | pmid:23232760 |
| Khadrawy YA et al. | The anticonvulant effect of cooling in comparison to α-lipoic acid: a neurochemical study. | 2013 | Neurochem. Res. | pmid:23389664 |
| Parsons TB et al. | Total synthesis of kottamide E. | 2013 | Chem. Commun. (Camb.) | pmid:23396320 |