Lipoic acid

Lipoic acid is a lipid of Fatty Acyls (FA) class.

Cross Reference

There are no associated biomedical information in the current reference collection.

Current reference collection contains 18962 references associated with Lipoic acid in LipidPedia. Due to lack of full text of references or no associated biomedical terms are recognized in our current text-mining method, we cannot extract any biomedical terms related to diseases, pathways, locations, functions, genes, lipids, and animal models from the associated reference collection.

Users can download the reference list at the bottom of this page and read the reference manually to find out biomedical information.


Here are additional resources we collected from PubChem and MeSH for Lipoic acid

Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Lipoic acid

MeSH term MeSH ID Detail
Hemolysis D006461 131 associated lipids
Stomach Ulcer D013276 75 associated lipids
Kidney Failure, Chronic D007676 51 associated lipids
Diabetes Mellitus D003920 90 associated lipids
Lead Poisoning D007855 4 associated lipids
Hearing Loss, Sensorineural D006319 8 associated lipids
Hypoxia D000860 23 associated lipids
Arrhythmias, Cardiac D001145 42 associated lipids
Acidosis, Lactic D000140 8 associated lipids
Lung Neoplasms D008175 171 associated lipids
Per page 10 20 50 100 | Total 177

PubChem Biomolecular Interactions and Pathways

NCBI Entrez Crosslinks

All references with Lipoic acid

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Per page 10 20 50 100 | Total 4476
Authors Title Published Journal PubMed Link
Ikuta N et al. Spectroscopic studies of R(+)-α-lipoic acid--cyclodextrin complexes. 2014 Int J Mol Sci pmid:25387076
Kamarudin MN et al. (R)-(+)-α-lipoic acid protected NG108-15 cells against H₂O₂-induced cell death through PI3K-Akt/GSK-3β pathway and suppression of NF-κβ-cytokines. 2014 Drug Des Devel Ther pmid:25336920
Costantino M et al. Peripheral neuropathy in obstetrics: efficacy and safety of α-lipoic acid supplementation. 2014 Eur Rev Med Pharmacol Sci pmid:25317815
Arroll MA et al. Nutritional interventions for the adjunctive treatment of schizophrenia: a brief review. 2014 Nutr J pmid:25228271
Byun E et al. α-Lipoic acid inhibits Helicobacter pylori-induced oncogene expression and hyperproliferation by suppressing the activation of NADPH oxidase in gastric epithelial cells. 2014 Mediators Inflamm. pmid:25210229
Garcia Lde B et al. Tissue response evaluation of the mucosa of the tympanic cavity of guinea pigs, when receiving biodegradable implant. 2014 Acta Cir Bras pmid:25185050
Yang Y et al. Alpha-lipoic acid attenuates insulin resistance and improves glucose metabolism in high fat diet-fed mice. 2014 Acta Pharmacol. Sin. pmid:25152027
Gonzalez P et al. Bimodal-hybrid heterocyclic amine targeting oxidative pathways and copper mis-regulation in Alzheimer's disease. 2014 Metallomics pmid:25144522
Yang Y et al. Alpha-lipoic acid improves high-fat diet-induced hepatic steatosis by modulating the transcription factors SREBP-1, FoxO1 and Nrf2 via the SIRT1/LKB1/AMPK pathway. 2014 J. Nutr. Biochem. pmid:25123628
Karaytug S et al. Comparison of the protective effects of antioxidant compounds in the liver and kidney of Cd- and Cr-exposed common carp. 2014 Environ. Toxicol. pmid:21987389
Tsou PS et al. Lipoic acid plays a role in scleroderma: insights obtained from scleroderma dermal fibroblasts. 2014 Arthritis Res. Ther. pmid:25123250
Sancheti H et al. Hypermetabolic state in the 7-month-old triple transgenic mouse model of Alzheimer's disease and the effect of lipoic acid: a 13C-NMR study. 2014 J. Cereb. Blood Flow Metab. pmid:25099753
Bharucha AE et al. Effects of aspirin & simvastatin and aspirin, simvastatin, & lipoic acid on heme oxygenase-1 in healthy human subjects. 2014 Neurogastroenterol. Motil. pmid:25093998
Ekinci M et al. Reduction of conjunctival fibrosis after trabeculectomy using topical α-lipoic acid in rabbit eyes. 2014 J. Glaucoma pmid:25055213
Pérez-Rentero S et al. Thioctic acid derivatives as building blocks to incorporate DNA oligonucleotides onto gold nanoparticles. 2014 Molecules pmid:25045890
Fernández-Galilea M et al. α-lipoic acid reduces fatty acid esterification and lipogenesis in adipocytes from overweight/obese subjects. 2014 Obesity (Silver Spring) pmid:25045030
Bassi E et al. Lipoic acid, but not tempol, preserves vascular compliance and decreases medial calcification in a model of elastocalcinosis. 2014 Braz. J. Med. Biol. Res. pmid:24519127
Braakman R and Smith E Metabolic evolution of a deep-branching hyperthermophilic chemoautotrophic bacterium. 2014 PLoS ONE pmid:24516572
Borziak K et al. Comparative genomic analysis reveals 2-oxoacid dehydrogenase complex lipoylation correlation with aerobiosis in archaea. 2014 PLoS ONE pmid:24489835
Letizia Mauro G et al. α-Lipoic acid and superoxide dismutase in the management of chronic neck pain: a prospective randomized study. 2014 Drugs R D pmid:24477618
Todorovic SM and Jevtovic-Todorovic V Redox regulation of neuronal voltage-gated calcium channels. 2014 Antioxid. Redox Signal. pmid:24161125
Ibrahim S et al. Selective cytotoxicity and combined effects of camptothecin or paclitaxel with sodium-R-alpha lipoate on A549 human non-small cell lung cancer cells. 2014 Nutr Cancer pmid:24063429
Grasso S et al. Effect of lipoic acid and α-glyceryl-phosphoryl-choline on astroglial cell proliferation and differentiation in primary culture. 2014 J. Neurosci. Res. pmid:24166560
Kim J et al. Alpha-lipoic acid protects against cisplatin-induced ototoxicity via the regulation of MAPKs and proinflammatory cytokines. 2014 Biochem. Biophys. Res. Commun. pmid:24796665
Huk-Kolega H et al. [Influence of lipoic acid on the level of TNF-alpha in spleen homogenates]. 2014 Pol. Merkur. Lekarski pmid:25095635
Keith D et al. Lipoic acid entrains the hepatic circadian clock and lipid metabolic proteins that have been desynchronized with advanced age. 2014 Biochem. Biophys. Res. Commun. pmid:24944020
Ide T Effect of dietary α-lipoic acid on the mRNA expression of genes involved in drug metabolism and antioxidation system in rat liver. 2014 Br. J. Nutr. pmid:24787548
Ghosal A et al. Biotin uptake by mouse and human pancreatic beta cells/islets: a regulated, lipopolysaccharide-sensitive carrier-mediated process. 2014 Am. J. Physiol. Gastrointest. Liver Physiol. pmid:24904078
Saleh MC et al. Co-administration of resveratrol and lipoic acid, or their synthetic combination, enhances neuroprotection in a rat model of ischemia/reperfusion. 2014 PLoS ONE pmid:24498217
Ledesma JC et al. Reduction in central H2O2 levels prevents voluntary ethanol intake in mice: a role for the brain catalase-H2O2 system in alcohol binge drinking. 2014 Alcohol. Clin. Exp. Res. pmid:24033657
Chen C et al. 4-methylene-2-octyl-5-oxotetrahydrofuran-3-carboxylic acid (C75), an inhibitor of fatty-acid synthase, suppresses the mitochondrial fatty acid synthesis pathway and impairs mitochondrial function. 2014 J. Biol. Chem. pmid:24784139
Nikolai S et al. R-α lipoic acid γ-cyclodextrin complex increases energy expenditure: a 4-month feeding study in mice. 2014 Nutrition pmid:24377457
Mehrotra A and Sandhir R Mitochondrial cofactors in experimental Huntington's disease: behavioral, biochemical and histological evaluation. 2014 Behav. Brain Res. pmid:24393741
Andrade AS et al. Alpha-lipoic acid restores tear production in an animal model of dry eye. 2014 Exp. Eye Res. pmid:24394592
Castro MC et al. Lipoic acid prevents fructose-induced changes in liver carbohydrate metabolism: role of oxidative stress. 2014 Biochim. Biophys. Acta pmid:24361606
Guo Y et al. Oral alpha-lipoic acid to prevent chemotherapy-induced peripheral neuropathy: a randomized, double-blind, placebo-controlled trial. 2014 Support Care Cancer pmid:24362907
Monserrat JM et al. Antioxidant, phase II and III responses induced by lipoic acid in the fish Jenynsia multidentata (Anablapidae) and its influence on endolsulfan accumulation and toxicity. 2014 Pestic Biochem Physiol pmid:24485309
Phillipson OT Management of the aging risk factor for Parkinson's disease. 2014 Neurobiol. Aging pmid:24246717
Stanković MN et al. The effects of α-lipoic acid on liver oxidative stress and free fatty acid composition in methionine-choline deficient diet-induced NAFLD. 2014 J Med Food pmid:24325457
Hahm JR et al. Alpha-lipoic acid attenuates adipocyte differentiation and lipid accumulation in 3T3-L1 cells via AMPK-dependent autophagy. 2014 Life Sci. pmid:24530288
Biresaw G et al. Synthesis and tribological investigation of lipoyl glycerides. 2014 J. Agric. Food Chem. pmid:24576015
Meng J et al. [Effects of lipoic acid on cytokines and chemokines in astrocytes stimulated with lipopolysaccharide]. 2014 Xi Bao Yu Fen Zi Mian Yi Xue Za Zhi pmid:24721398
Deslauriers J et al. Implication of the ERK/MAPK pathway in antipsychotics-induced dopamine D2 receptor upregulation and in the preventive effects of (±)-α-lipoic acid in SH-SY5Y neuroblastoma cells. 2014 J. Mol. Neurosci. pmid:24203573
Weng CY et al. Arsenic trioxide induces unfolded protein response in vascular endothelial cells. 2014 Arch. Toxicol. pmid:23892647
Vidović B et al. Effect of alpha-lipoic acid supplementation on oxidative stress markers and antioxidative defense in patients with schizophrenia. 2014 Psychiatr Danub pmid:25191766
Carrier B et al. Alpha-lipoic acid reduces LDL-particle number and PCSK9 concentrations in high-fat fed obese Zucker rats. 2014 PLoS ONE pmid:24595397
Khalili M et al. Effect of lipoic acid consumption on oxidative stress among multiple sclerosis patients: a randomized controlled clinical trial. 2014 Nutr Neurosci pmid:23485514
Kates SA et al. Lipoic acid analogs with enhanced pharmacological activity. 2014 Bioorg. Med. Chem. pmid:24316353
Dwivedi N et al. Alpha-lipoic acid protects oxidative stress, changes in cholinergic system and tissue histopathology during co-exposure to arsenic-dichlorvos in rats. 2014 Environ. Toxicol. Pharmacol. pmid:24291368
Gras D et al. GLUT1 deficiency syndrome: an update. 2014 Rev. Neurol. (Paris) pmid:24269118