Lipoic acid

Lipoic acid is a lipid of Fatty Acyls (FA) class.

Cross Reference

There are no associated biomedical information in the current reference collection.

Current reference collection contains 18962 references associated with Lipoic acid in LipidPedia. Due to lack of full text of references or no associated biomedical terms are recognized in our current text-mining method, we cannot extract any biomedical terms related to diseases, pathways, locations, functions, genes, lipids, and animal models from the associated reference collection.

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Here are additional resources we collected from PubChem and MeSH for Lipoic acid

Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Lipoic acid

MeSH term MeSH ID Detail
Hemolysis D006461 131 associated lipids
Stomach Ulcer D013276 75 associated lipids
Kidney Failure, Chronic D007676 51 associated lipids
Diabetes Mellitus D003920 90 associated lipids
Lead Poisoning D007855 4 associated lipids
Hearing Loss, Sensorineural D006319 8 associated lipids
Hypoxia D000860 23 associated lipids
Arrhythmias, Cardiac D001145 42 associated lipids
Acidosis, Lactic D000140 8 associated lipids
Lung Neoplasms D008175 171 associated lipids
Per page 10 20 50 100 | Total 177

PubChem Biomolecular Interactions and Pathways

NCBI Entrez Crosslinks

All references with Lipoic acid

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Per page 10 20 50 100 | Total 4476
Authors Title Published Journal PubMed Link
Wang J et al. Xenobiotics and loss of tolerance in primary biliary cholangitis. 2016 World J. Gastroenterol. pmid:26755880
Ki SH and Kim SG Phase II enzyme induction by alpha-lipoic acid through phosphatidylinositol 3-kinase-dependent C/EBPs activation. 2008 Xenobiotica pmid:18570160
Wang X et al. Pharmacokinetics of lipoyl vildagliptin, a novel dipeptidyl peptidase IV inhibitor after oral administration in rats. 2010 Xenobiotica pmid:20735236
Meng J et al. [Effects of lipoic acid on cytokines and chemokines in astrocytes stimulated with lipopolysaccharide]. 2014 Xi Bao Yu Fen Zi Mian Yi Xue Za Zhi pmid:24721398
Chen SC et al. [Alpha lipoic acid affect the function of EPCs incubated by high-glucose]. 2012 Xi Bao Yu Fen Zi Mian Yi Xue Za Zhi pmid:22394630
DEGUCHI Y and MIURA K [Studies on the synthesis of thioctic acid and its related compounds. VII. Synthesis of thioctamide. (2)]. 1962 Yakugaku Zasshi pmid:14026471
DEGUCHI Y et al. [Studies on the synthesis of thioctic acid and its related compounds. VI. Synthesis of thioctamide. (1)]. 1962 Yakugaku Zasshi pmid:14026472
Okuda N et al. [Studies on lipoic acid derivatives. I. On the microbiological activity of DL-alpha-lipoic acid derivatives]. 1965 Yakugaku Zasshi pmid:4953470
Okudan N et al. Alpha lipoic acid treatment improved endothelium-dependent relaxation in diabetic rat aorta. 2011 Yakugaku Zasshi pmid:21532270
Kaku H [Thermodynamically controlled deracemization utilizing inclusion complexation]. 2008 Yakugaku Zasshi pmid:18827463
DEGUCHI Y and MIURA K [STUDIES ON THE SYNTHESIS OF THIOCTIC ACID AND ITS RELATED COMPOUNDS. XIV. SYNTHESIS OF (+)-THIOCTAMIDE]. 1964 Yakugaku Zasshi pmid:14207116
IGUCHI S et al. [STUDIES ON MEDICINAL PREPARATIONS BY GAS CHROMATOGRAPHY. 3. GAS CHROMATOGRAPHY OF THIOCTIC ACID AND THIOCTAMIDE]. 1964 Yakugaku Zasshi pmid:14236244
Oshima Y et al. [Studies on DL-alpha-lipoic acid derivatives. II. On the pharmacological activities of 4-(DL-alpha-lipamido)butyric acid (LABA)]. 1965 Yakugaku Zasshi pmid:5318985
DEGUCHI Y and NAKANISHI K [STUDIES ON THE SYNTHESIS OF THIOCTIC ACID AND ITS RELATED COMPOUNDS. IX. SYNTHESIS OF BOUND COMPOUNDS OF THIOCTIC ACID DERIVATIVES AND VITAMIN B1]. 1963 Yakugaku Zasshi pmid:14048372
DEGUCHI Y and NAKANISHI K [STUDIES ON THE SYNTHESIS OF THIOCTIC ACID AND ITS RELATED COMPOUNDS. X. SYNTHESIS OF BOUND COMPOUNDS OF THIOCTIC ACID DERIVATIVES AND VITAMIN B1]. 1963 Yakugaku Zasshi pmid:14048373
DEGUCHI Y and MIURA K [STUDIES ON THE SYNTHESIS OF THIOCTIC ACID AND ITS RELATED COMPOUNDS. XI. SYNTHESIS OF BOUND COMPOUNDS OF THIOCTIC ACID DERIVATIVES AND VITAMIN B1]. 1963 Yakugaku Zasshi pmid:14048374
DEGUCHI Y et al. [STUDIES ON THE SYNTHESIS OF THIOCTIC ACID AND ITS RELATED COMPOUNDS. XII. NEW SYNTHESIS OF 6-ACYLTHIO-8-CHLOROOECTANOIC ESTERS]. 1963 Yakugaku Zasshi pmid:14048375
DEGUCHI Y and MIURA K [STUDIES ON THE SYNTHESIS OF THIOCTIC ACID AND ITS RELATED COMPOUNDS. XIII. SYNTHESIS OF BOUND COMPOUNDS OF THIOCTIC ACID DERIVATIVES AND VITAMIN B1]. 1963 Yakugaku Zasshi pmid:14048376
DEGUCHI Y and MIURA K [STUDIES ON THE SYNTHESIS OF THIOCTIC ACID AND ITS RELATED COMPOUNDS. VIII. SYNTHESIS OF N-THIOCTOYLAMINO ACIDS]. 1963 Yakugaku Zasshi pmid:14048382
Liu RT and Lü QJ [Progress in the research on multi-target-directed drugs against Alzheimer's disease]. 2009 Yao Xue Xue Bao pmid:19449521
Zhu YQ et al. [Study of antiradiation drugs. III. Synthesis of some tertiary amino derivatives of 1,2-dithiolane (author's transl)]. 1980 Yao Xue Xue Bao pmid:6789613
Zhou ZW et al. [Studies on antiradiation drugs: synthesis of amino-lipoates and related compounds]. 1984 Yao Xue Xue Bao pmid:6443334
SHIE CS [STUDIES ON THE ANTIDOTAL EFFECTS OF LIPOIC ACID AGAINST POTASSIUM ANTIMONY TARTRATE]. 1965 Yao Xue Xue Bao pmid:14321747
Hermes FA and Cronan JE The role of the Saccharomyces cerevisiae lipoate protein ligase homologue, Lip3, in lipoic acid synthesis. 2013 Yeast pmid:23960015
Stanchi F et al. Characterization of 16 novel human genes showing high similarity to yeast sequences. 2001 Yeast pmid:11124703
Choi JH et al. α-Lipoic Acid Inhibits Expression of IL-8 by Suppressing Activation of MAPK, Jak/Stat, and NF-κB in H. pylori-Infected Gastric Epithelial AGS Cells. 2016 Yonsei Med. J. pmid:26632410
Atmaca G Antioxidant effects of sulfur-containing amino acids. 2004 Yonsei Med. J. pmid:15515186
Lee EY et al. Blockade of oxidative stress by vitamin C ameliorates albuminuria and renal sclerosis in experimental diabetic rats. 2007 Yonsei Med. J. pmid:17963344
Mittmann W [On the clinical picture and therapy of edible gyromitra poisoning (Gyromitra esculenta)]. 1968 Z Arztl Fortbild (Jena) pmid:4878519
KRUESKEMPER HL and KORUS W [The effect of lipoic acid on degradation of cortisone in experimental fatty liver]. 1961 Z Gesamte Exp Med pmid:13754566
Palyza V et al. [Biochemical findings in Amanita phalloides intoxication]. 1971 Z Gesamte Inn Med pmid:4937104
Kähler W et al. [Diabetes mellitus--a free radical-associated disease. Results of adjuvant antioxidant supplementation]. 1993 Z Gesamte Inn Med pmid:8390768
BALOGH E et al. [ON THIOCTIC ACID THERAPY OF SOME PHOTODERMATOSES]. 1964 Z Haut Geschlechtskr pmid:14224704
Znamenácek K and Pribylová H [Adenosine triphosphoric acid in the treatment of newborn infants of diabetic mothers]. 1966 Z Kinderheilkd pmid:4862093
Mattulat A and Baltes W Determination of lipoic acid in meat of commercial quality. 1992 Z Lebensm Unters Forsch pmid:1598790
Grzycki S and Królikowska-Prasal I Histotopochemical studies on specific dehydrogenases in the liver after thioctacid application. 1972 Z Mikrosk Anat Forsch pmid:4572862
Grzycki S and Królikowska-Prasal I Histochemical studies of specific dehydrogenases in the jejunum after thioctacid application. 1972 Z Mikrosk Anat Forsch pmid:4583756
Diringer H Lipoamidase activity in virus induced tumours and in the corresponding normal tissue. 1971 Z. Naturforsch. B pmid:4400305
Goedde HW et al. [On the effect of substituted alpha-lipoic acids on the lipoamide oxidoreductase reaction]. 1967 Z. Naturforsch. B pmid:4384724
Schempp H et al. Stereospecific reduction of R(+)-thioctic acid by porcine heart lipoamide dehydrogenase/diaphorase. 1994 Sep-Oct Z. Naturforsch., C, J. Biosci. pmid:7945680
Nohl H and Gille L Evaluation of the antioxidant capacity of ubiquinol and dihydrolipoic acid. 1998 Mar-Apr Z. Naturforsch., C, J. Biosci. pmid:9618938
Christow CP [Experiments on the influence of metabolites and antimetabolites on the model of Trichomonas vaginalis. V. Relationship between vitamin-B-complexes and Trichomonas vaginalis]. 1971 Zentralbl Bakteriol Orig A pmid:4403543
Esser G [Peculiarities of the surgical technic in the performance of portocaval anastomoses]. 1967 Zentralbl Chir pmid:4872291
Obeid H [Thioctic acid in liver diseases]. 1979 ZFA (Stuttgart) pmid:43630
Solov'eva EIu et al. [The free-radical processes and antioxidant therapy in brain ischemia]. 2008 Zh Nevrol Psikhiatr Im S S Korsakova pmid:18577933
Kovrazhkina EA et al. [Possibilities and perspectives of berlition usage in the treatment of alcohol polyneuropathy]. 2004 Zh Nevrol Psikhiatr Im S S Korsakova pmid:15002318
Strokov IA et al. [Efficacy of thiolepta in diabetic polyneuropathy: results of the study ETIKA]. 2013 Zh Nevrol Psikhiatr Im S S Korsakova pmid:23739501
Skoromets AA et al. [Complex evaluation of treatment efficacy in diabetic encephalopathy]. 2002 Zh Nevrol Psikhiatr Im S S Korsakova pmid:11957343
Artamonova VG and Lashina EL [Tiolepta (thioctic acid) in the treatment of vibration disease]. 2011 Zh Nevrol Psikhiatr Im S S Korsakova pmid:21434468
Zhivolupov SA et al. [Metabolic therapy in neurology]. 2013 Zh Nevrol Psikhiatr Im S S Korsakova pmid:23994919
Balabolkin MI and Kreminskaia VM [Diabetic neuropathy]. 2000 Zh Nevrol Psikhiatr Im S S Korsakova pmid:11081270
Kovrazhkina EA [Demyelinating polyneuropathies in patients with diabetes mellitus and chronic alcoholic intoxication]. 2012 Zh Nevrol Psikhiatr Im S S Korsakova pmid:22951780
Vorob'eva OV [Thioctic (alpha-lipoic) acid-spectrum of clinical use]. 2011 Zh Nevrol Psikhiatr Im S S Korsakova pmid:22500323
Sergienko VA et al. [The effect of long-chain polyunsaturated higher ω-3 fatty acids, benfotiamine and α-lipoic acid on the lipid metabolism in patients with diabetes mellitus type 2 and cardiovascular autonomic neuropathy]. 2013 Zh Nevrol Psikhiatr Im S S Korsakova pmid:24429949
Baranova OA et al. [A search for new markers of oxidative stress in brain ischemia for the optimization of treatment approaches]. 2011 Zh Nevrol Psikhiatr Im S S Korsakova pmid:22433805
Fedin AI et al. [Pharmacotherapy of endothelial dysfunction in patients with atherosclerotic brain ischemia]. 2013 Zh Nevrol Psikhiatr Im S S Korsakova pmid:24300805
Medvedeva LA et al. [Neurometabolic therapy of diabetic neuropathy]. 2006 Zh Nevrol Psikhiatr Im S S Korsakova pmid:16921725
Al'-Zamil' MKh and Brezheva EV [Implication of alpha-lipoic acid preparations in the treatment of diabetic neuropathy]. 2008 Zh Nevrol Psikhiatr Im S S Korsakova pmid:18427500
Strokov IA et al. [The efficacy of the intravenous administration of the trometamol salt of thioctic (alpha-lipoic) acid in diabetic neuropathy]. 1999 Zh Nevrol Psikhiatr Im S S Korsakova pmid:10441861
Iksanova GR et al. [Assessment of berlition effectiveness in ischemic stroke with CT perfusion imaging of the brain]. 2008 Zh Nevrol Psikhiatr Im S S Korsakova pmid:18427519
Al-Zamil MKh [The use of dipyridamole (curantyl) in combination with alpha-lipoic acid in the treatment of diabetic neuropathy with retinopathy]. 2008 Zh Nevrol Psikhiatr Im S S Korsakova pmid:18833114
Kolesnichenko LS et al. [The blood glutathione system in cerebral vascular diseases and its treatment with alpha-lipoic acid]. 2008 Zh Nevrol Psikhiatr Im S S Korsakova pmid:18833169
Chukanova EI and Sokolova NA [Efficiency of thioctacid in dyscirculatory encephalopathy]. 2001 Zh Nevrol Psikhiatr Im S S Korsakova pmid:11765609
Xia SX et al. [Biochemical mechanism of radioprotection by diethyllipoamide]. 1982 Zhongguo Yao Li Xue Bao pmid:6293249
Wu DZ et al. [Relationship between diethyl lipoamide (DELA) induced tissue hypoxia and radiation-protective effect in mice]. 1983 Zhongguo Yao Li Xue Bao pmid:6230878
Xia SX et al. [Effect of diethyllipoamide on DNA damage and repair of gamma-irradiated mouse bone marrow cells]. 1984 Zhongguo Yao Li Xue Bao pmid:6240902
Xia SX et al. [The in vivo disposition of diethyllipoamide (author's transl)]. 1982 Zhongguo Yao Li Xue Bao pmid:6214148
Yang L et al. [Effect of alpha-lipoic acid combined with transient intensive insulin therapy on adipokine level in patients with type 2 diabetic perineuropathy]. 2013 Zhongguo Yi Xue Ke Xue Yuan Xue Bao pmid:23827078
Li XZ et al. [Extract of Ginkgo biloba and alpha-lipoic acid attenuate advanced glycation end products accumulation and RAGE expression in diabetic nephropathy rats]. 2011 Zhongguo Zhong Xi Yi Jie He Za Zhi pmid:21608227
Zhang YZ et al. [Effect of alpha-lipoic acid on hearing functions after cerebral concussion]. 2010 Zhonghua Er Bi Yan Hou Tou Jing Wai Ke Za Zhi pmid:20398525
Liu CB et al. [Effects of α-lipoic acid and vitamin C on oxidative stress in rat exposed to chronic arsenic toxicity]. 2010 Zhonghua Lao Dong Wei Sheng Zhi Ye Bing Za Zhi pmid:21241596
Huang YD et al. [The effect of oral alpha-lipoic acid in overweight/obese individuals on brachial-ankle pulse wave velocity and supine blood pressure: a randomized, crossover, double-blind, placebo-controlled trial]. 2011 Zhonghua Liu Xing Bing Xue Za Zhi pmid:21457668
Yao LS et al. [Expressions of NOS isoforms in the cavernous tissues of diabetic rat models]. 2009 Zhonghua Nan Ke Xue pmid:20112741
Sun L and Zhang JS [Effects of DL-alpha-lipoic acid on the experimentally induced diabetic cataract in rats]. 2004 Zhonghua Yan Ke Za Zhi pmid:15307993
Gu XM et al. [Efficacy and safety of high-dose α-lipoic acid in the treatment of diabetic polyneuropathy]. 2010 Zhonghua Yi Xue Za Zhi pmid:21092474
Liu F et al. [Curative effect of alpha-lipoic acid on peripheral neuropathy in type 2 diabetes: a clinical study]. 2007 Zhonghua Yi Xue Za Zhi pmid:18167250