| MeSH term | MeSH ID | Detail |
|---|---|---|
| Hemolysis | D006461 | 131 associated lipids |
| Stomach Ulcer | D013276 | 75 associated lipids |
| Kidney Failure, Chronic | D007676 | 51 associated lipids |
| Diabetes Mellitus | D003920 | 90 associated lipids |
| Lead Poisoning | D007855 | 4 associated lipids |
| Hearing Loss, Sensorineural | D006319 | 8 associated lipids |
| Hypoxia | D000860 | 23 associated lipids |
| Arrhythmias, Cardiac | D001145 | 42 associated lipids |
| Acidosis, Lactic | D000140 | 8 associated lipids |
| Lung Neoplasms | D008175 | 171 associated lipids |
Lipoic acid
Lipoic acid is a lipid of Fatty Acyls (FA) class.
Cross Reference
There are no associated biomedical information in the current reference collection.
Current reference collection contains 18962 references associated with Lipoic acid in LipidPedia. Due to lack of full text of references or no associated biomedical terms are recognized in our current text-mining method, we cannot extract any biomedical terms related to diseases, pathways, locations, functions, genes, lipids, and animal models from the associated reference collection.
Users can download the reference list at the bottom of this page and read the reference manually to find out biomedical information.
Here are additional resources we collected from PubChem and MeSH for Lipoic acid
Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with Lipoic acid
PubChem Biomolecular Interactions and Pathways
NCBI Entrez Crosslinks
All references with Lipoic acid
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Posner MG et al. | Post-translational modification in the archaea: structural characterization of multi-enzyme complex lipoylation. | 2013 | Biochem. J. | pmid:23116157 |
| Michikoshi H et al. | α-Lipoic acid-induced inhibition of proliferation and met phosphorylation in human non-small cell lung cancer cells. | 2013 | Cancer Lett. | pmid:23507559 |
| Lobato RO et al. | The role of lipoic acid in the protection against of metallic pollutant effects in the shrimp Litopenaeus vannamei (Crustacea, Decapoda). | 2013 | Comp. Biochem. Physiol., Part A Mol. Integr. Physiol. | pmid:23507566 |
| Wongmekiat O et al. | Alpha-lipoic acid attenuates renal injury in rats with obstructive nephropathy. | 2013 | Biomed Res Int | pmid:24288661 |
| Deslauriers J et al. | α-Lipoic acid interaction with dopamine D2 receptor-dependent activation of the Akt/GSK-3β signaling pathway induced by antipsychotics: potential relevance for the treatment of schizophrenia. | 2013 | J. Mol. Neurosci. | pmid:22975849 |
| Hermes FA and Cronan JE | The role of the Saccharomyces cerevisiae lipoate protein ligase homologue, Lip3, in lipoic acid synthesis. | 2013 | Yeast | pmid:23960015 |
| Prieto-Hontoria PL et al. | Effects of lipoic acid on AMPK and adiponectin in adipose tissue of low- and high-fat-fed rats. | 2013 | Eur J Nutr | pmid:22664981 |
| Bhadri N et al. | Amelioration of behavioural, biochemical, and neurophysiological deficits by combination of monosodium glutamate with resveratrol/alpha-lipoic acid/coenzyme Q10 in rat model of cisplatin-induced peripheral neuropathy. | 2013 | ScientificWorldJournal | pmid:24489506 |
| Lee SM et al. | Surface-engineered nanomaterials as X-ray absorbing adjuvant agents for Auger-mediated chemo-radiation. | 2013 | Nanoscale | pmid:23657262 |
| Tang X et al. | Effects of heat treatment on structural modification and in vivo antioxidant capacity of soy protein. | 2012 Nov-Dec | Nutrition | pmid:22858204 |
| Plotnikov M et al. | Influence of antioxidant complex on the adhesion of leukocytes in chronic venous insufficiency of lower limbs in rats. | 2012 Nov-Dec | Indian J Pharmacol | pmid:23248399 |
| Zur E | Burning mouth syndrome: a discussion of a complex pathology. | 2012 May-Jun | Int J Pharm Compd | pmid:23050296 |
| Campos PM et al. | Efficacy of cosmetic formulations containing dispersion of liposome with magnesium ascorbyl phosphate, alpha-lipoic acid and kinetin. | 2012 May-Jun | Photochem. Photobiol. | pmid:22236139 |
| Lee SG et al. | Effect of lipoic acid on expression of angiogenic factors in diabetic rat retina. | 2012 Jan-Feb | Clin. Experiment. Ophthalmol. | pmid:21902786 |
| Villanueva C and Kross RD | Antioxidant-induced stress. | 2012 | Int J Mol Sci | pmid:22408440 |
| McLean JS et al. | Identifying low pH active and lactate-utilizing taxa within oral microbiome communities from healthy children using stable isotope probing techniques. | 2012 | PLoS ONE | pmid:22403637 |
| Bruin JE et al. | Maternal antioxidants prevent β-cell apoptosis and promote formation of dual hormone-expressing endocrine cells in male offspring following fetal and neonatal nicotine exposure. | 2012 | J Diabetes | pmid:22385833 |
| Rouault TA | Biogenesis of iron-sulfur clusters in mammalian cells: new insights and relevance to human disease. | 2012 | Dis Model Mech | pmid:22382365 |
| Miller SL et al. | Antioxidant therapies: a potential role in perinatal medicine. | 2012 | Neuroendocrinology | pmid:22377769 |
| Ko SH and Cha BY | Diabetic peripheral neuropathy in type 2 diabetes mellitus in Korea. | 2012 | Diabetes Metab J | pmid:22363916 |
| Kim JI et al. | Induction of ER Stress-Mediated Apoptosis by α-Lipoic Acid in A549 Cell Lines. | 2012 | Korean J Thorac Cardiovasc Surg | pmid:22363901 |
| Guerra SM et al. | LAL regulators SCO0877 and SCO7173 as pleiotropic modulators of phosphate starvation response and actinorhodin biosynthesis in Streptomyces coelicolor. | 2012 | PLoS ONE | pmid:22363654 |
| Yeni D et al. | Effect of α-lipoic acid on sperm quality, reproductive tract measures in thinner exposed rats. | 2012 | Andrologia | pmid:21919941 |
| Martins AR et al. | Mechanisms underlying skeletal muscle insulin resistance induced by fatty acids: importance of the mitochondrial function. | 2012 | Lipids Health Dis | pmid:22360800 |
| Galea E et al. | Oxidative stress underlying axonal degeneration in adrenoleukodystrophy: a paradigm for multifactorial neurodegenerative diseases? | 2012 | Biochim. Biophys. Acta | pmid:22353463 |
| Gerlinger I | [Burning sensation in oral cavity--burning mouth syndrome in everyday medical practice]. | 2012 | Ideggyogy Sz | pmid:23126213 |
| Han Z et al. | Robust photogeneration of H2 in water using semiconductor nanocrystals and a nickel catalyst. | 2012 | Science | pmid:23138979 |
| Kaplan KA et al. | Alpha-lipoic acid protects against indomethacin-induced gastric oxidative toxicity by modulating antioxidant system. | 2012 | J. Food Sci. | pmid:23057764 |
| Perluigi M and Butterfield DA | Oxidative Stress and Down Syndrome: A Route toward Alzheimer-Like Dementia. | 2012 | Curr Gerontol Geriatr Res | pmid:22203843 |
| Mazza A et al. | The role of metformin in the management of NAFLD. | 2012 | Exp Diabetes Res | pmid:22194737 |
| Kharbanda KK et al. | Betaine treatment attenuates chronic ethanol-induced hepatic steatosis and alterations to the mitochondrial respiratory chain proteome. | 2012 | Int J Hepatol | pmid:22187660 |
| Liu DS et al. | Diels-Alder cycloaddition for fluorophore targeting to specific proteins inside living cells. | 2012 | J. Am. Chem. Soc. | pmid:22176354 |
| Narisawa A et al. | Mutations in genes encoding the glycine cleavage system predispose to neural tube defects in mice and humans. | 2012 | Hum. Mol. Genet. | pmid:22171071 |
| Sha SH et al. | Antioxidant-enriched diet does not delay the progression of age-related hearing loss. | 2012 | Neurobiol. Aging | pmid:22154190 |
| Othman AI et al. | Alfa-lipoic acid protects testosterone secretion pathway and sperm quality against 4-tert-octylphenol induced reproductive toxicity. | 2012 | Ecotoxicol. Environ. Saf. | pmid:22560493 |
| Degola F et al. | Development of a simple and high-throughput method for detecting aflatoxins production in culture media. | 2012 | Lett. Appl. Microbiol. | pmid:22568641 |
| Shimoda S et al. | The role of natural killer (NK) and NK T cells in the loss of tolerance in murine primary biliary cirrhosis. | 2012 | Clin. Exp. Immunol. | pmid:22519590 |
| Shay KP et al. | Cap-independent Nrf2 translation is part of a lipoic acid-stimulated detoxification stress response. | 2012 | Biochim. Biophys. Acta | pmid:22521877 |
| Yi X et al. | Reduced expression of lipoic acid synthase accelerates diabetic nephropathy. | 2012 | J. Am. Soc. Nephrol. | pmid:22021711 |
| Veskoukis AS et al. | Dietary oxidative stress and antioxidant defense with an emphasis on plant extract administration. | 2012 | Cell Stress Chaperones | pmid:21956695 |
| Askwith T et al. | Taurine reduces nitrosative stress and nitric oxide synthase expression in high glucose-exposed human Schwann cells. | 2012 | Exp. Neurol. | pmid:21952043 |
| Zaitone SA et al. | Acetyl-L-carnitine and α-lipoic acid affect rotenone-induced damage in nigral dopaminergic neurons of rat brain, implication for Parkinson's disease therapy. | 2012 | Pharmacol. Biochem. Behav. | pmid:21958946 |
| Fuchs TM et al. | Toward a Systemic Understanding of Listeria monocytogenes Metabolism during Infection. | 2012 | Front Microbiol | pmid:22347216 |
| He L et al. | Alpha lipoic acid protects heart against myocardial ischemia-reperfusion injury through a mechanism involving aldehyde dehydrogenase 2 activation. | 2012 | Eur. J. Pharmacol. | pmid:22266491 |
| Yao H et al. | Reaction characteristics of andrographolide and its analogue AL-1 with GSH, as a simple chemical simulation of NF-κB inhibition. | 2012 | Molecules | pmid:22241468 |
| Pfeffer G et al. | Treatment for mitochondrial disorders. | 2012 | Cochrane Database Syst Rev | pmid:22513923 |
| Gao J et al. | Colloidal stability of gold nanoparticles modified with thiol compounds: bioconjugation and application in cancer cell imaging. | 2012 | Langmuir | pmid:22276658 |
| Giorgi C et al. | Mitochondrial calcium homeostasis as potential target for mitochondrial medicine. | 2012 | Mitochondrion | pmid:21798374 |
| Connell BJ et al. | UPEI-100, a conjugate of lipoic acid and apocynin, mediates neuroprotection in a rat model of ischemia/reperfusion. | 2012 | Am. J. Physiol. Regul. Integr. Comp. Physiol. | pmid:22277933 |
| Al-Mulla F et al. | A new model for raf kinase inhibitory protein induced chemotherapeutic resistance. | 2012 | PLoS ONE | pmid:22279539 |
| Valdecantos MP et al. | Lipoic acid improves mitochondrial function in nonalcoholic steatosis through the stimulation of sirtuin 1 and sirtuin 3. | 2012 | Obesity (Silver Spring) | pmid:22327056 |
| Bitar MS and Al-Mulla F | ROS constitute a convergence nexus in the development of IGF1 resistance and impaired wound healing in a rat model of type 2 diabetes. | 2012 | Dis Model Mech | pmid:22362362 |
| Cacciatore I et al. | (R)-α-lipoyl-glycyl-L-prolyl-L-glutamyl dimethyl ester codrug as a multifunctional agent with potential neuroprotective activities. | 2012 | ChemMedChem | pmid:22976949 |
| Xie R et al. | Alpha-lipoic acid pre- and post-treatments provide protection against in vitro ischemia-reperfusion injury in cerebral endothelial cells via Akt/mTOR signaling. | 2012 | Brain Res. | pmid:22982730 |
| Chen SA et al. | Topical treatment with anti-oxidants and Au nanoparticles promote healing of diabetic wound through receptor for advance glycation end-products. | 2012 | Eur J Pharm Sci | pmid:22985875 |
| Montero O et al. | Determination of lipoic acid, Trolox methyl ether and tocopherols in human plasma by liquid-chromatography and ion-trap tandem mass spectrometry. | 2012 | Biomed. Chromatogr. | pmid:22222855 |
| Mollo R et al. | Effect of α-lipoic acid on platelet reactivity in type 1 diabetic patients. | 2012 | Diabetes Care | pmid:22228743 |
| Terán R et al. | The life span of Drosophila melanogaster is affected by melatonin and thioctic acid. | 2012 | Invest Clin | pmid:23248969 |
| Palui G et al. | Poly(ethylene glycol)-based multidentate oligomers for biocompatible semiconductor and gold nanocrystals. | 2012 | Langmuir | pmid:22201293 |
| Larkin J et al. | A cost effective complement to managing the vitamin D deficient and anemic dialysis patient in the bundled world. | 2012 | Nephrol News Issues | pmid:22870564 |
| St-Louis R et al. | Reactive oxygen species are required for the hypothalamic osmoregulatory response. | 2012 | Endocrinology | pmid:22202167 |
| Yu AL et al. | TGF-β(2)- and H(2)O(2)-induced biological changes in optic nerve head astrocytes are reduced by the antioxidant alpha-lipoic acid. | 2012 | Ophthalmic Res. | pmid:22710901 |
| Min AK et al. | Alpha-lipoic acid attenuates methionine choline deficient diet-induced steatohepatitis in C57BL/6 mice. | 2012 | Life Sci. | pmid:22154902 |
| Connell BJ and Saleh TM | Co-administration of apocynin with lipoic acid enhances neuroprotection in a rat model of ischemia/reperfusion. | 2012 | Neurosci. Lett. | pmid:22155048 |
| Imik H et al. | Effects of ascorbic acid and α-lipoic acid on performance and meat quality of broilers subjected to heat stress. | 2012 | Br. Poult. Sci. | pmid:23398425 |
| Ahmed HH | Modulatory effects of vitamin E, acetyl-L-carnitine and α-lipoic acid on new potential biomarkers for Alzheimer's disease in rat model. | 2012 | Exp. Toxicol. Pathol. | pmid:21183322 |
| Munasinghe VS et al. | New advances in the in-vitro culture of Dientamoeba fragilis. | 2012 | Parasitology | pmid:22336222 |
| Tsikas D et al. | Antioxidants and endothelial dysfunction in young and elderly people: is flow-mediated dilation useful to assess acute effects? | 2012 | Hypertension | pmid:22665128 |
| DU SC et al. | ROS-mediated lipopolysaccharide-induced apoptosis in INS-1 cells by modulation of Bcl-2 and Bax. | 2012 | Cell. Mol. Biol. (Noisy-le-grand) | pmid:22455982 |
| Chen WL et al. | α-Lipoic acid regulates lipid metabolism through induction of sirtuin 1 (SIRT1) and activation of AMP-activated protein kinase. | 2012 | Diabetologia | pmid:22456698 |
| Shang L et al. | Microwave-assisted rapid synthesis of luminescent gold nanoclusters for sensing Hg2+ in living cells using fluorescence imaging. | 2012 | Nanoscale | pmid:22460520 |
| Nunnery JK et al. | Biosynthetically intriguing chlorinated lipophilic metabolites from geographically distant tropical marine cyanobacteria. | 2012 | J. Org. Chem. | pmid:22489775 |
| Cohen JD et al. | Site-specific protein modification using lipoic acid ligase and bis-aryl hydrazone formation. | 2012 | Chembiochem | pmid:22492621 |
| Galasko DR et al. | Antioxidants for Alzheimer disease: a randomized clinical trial with cerebrospinal fluid biomarker measures. | 2012 | Arch. Neurol. | pmid:22431837 |
| Valdecantos MP et al. | Lipoic acid administration prevents nonalcoholic steatosis linked to long-term high-fat feeding by modulating mitochondrial function. | 2012 | J. Nutr. Biochem. | pmid:22464149 |
| Gokce EH et al. | Resveratrol-loaded solid lipid nanoparticles versus nanostructured lipid carriers: evaluation of antioxidant potential for dermal applications. | 2012 | Int J Nanomedicine | pmid:22605933 |
| Schalkwijk CG and Miyata T | Early- and advanced non-enzymatic glycation in diabetic vascular complications: the search for therapeutics. | 2012 | Amino Acids | pmid:20960212 |
| Henderson LC et al. | A comparative assessment of α-lipoic acid N-phenylamides as non-steroidal androgen receptor antagonists both on and off gold nanoparticles. | 2012 | Bioorg. Chem. | pmid:22196975 |
| Han T et al. | A systematic review and meta-analysis of α-lipoic acid in the treatment of diabetic peripheral neuropathy. | 2012 | Eur. J. Endocrinol. | pmid:22837391 |
| Tournebize J et al. | Impact of gold nanoparticle coating on redox homeostasis. | 2012 | Int J Pharm | pmid:22841848 |
| Jung TS et al. | α-lipoic acid prevents non-alcoholic fatty liver disease in OLETF rats. | 2012 | Liver Int. | pmid:22863080 |
| Macêdo DS et al. | Effects of alpha-lipoic acid in an animal model of mania induced by D-amphetamine. | 2012 | Bipolar Disord | pmid:22897629 |
| Mrakic-Sposta S et al. | Assessment of a standardized ROS production profile in humans by electron paramagnetic resonance. | 2012 | Oxid Med Cell Longev | pmid:22900129 |
| Thakurta IG et al. | Dietary supplementation with N-acetyl cysteine, α-tocopherol and α-lipoic acid reduces the extent of oxidative stress and proinflammatory state in aged rat brain. | 2012 | Biogerontology | pmid:22851277 |
| Colligris B et al. | Recent patents and developments in glaucoma biomarkers. | 2012 | Recent Pat Endocr Metab Immune Drug Discov | pmid:22827637 |
| Kodama S et al. | Direct enantioseparation of lipoic acid in dietary supplements by capillary electrophoresis using trimethyl-β-cyclodextrin as a chiral selector. | 2012 | Electrophoresis | pmid:22887166 |
| Hussein A et al. | Ameliorating effect of DL-α-lipoic acid against cisplatin-induced nephrotoxicity and cardiotoxicity in experimental animals. | 2012 | Drug Discov Ther | pmid:22890205 |
| López-Erauskin J et al. | Oxidative stress modulates mitochondrial failure and cyclophilin D function in X-linked adrenoleukodystrophy. | 2012 | Brain | pmid:23250880 |
| Yi X et al. | Reduced alpha-lipoic acid synthase gene expression exacerbates atherosclerosis in diabetic apolipoprotein E-deficient mice. | 2012 | Atherosclerosis | pmid:22658261 |
| Kim H et al. | α-Lipoic acid attenuates vascular calcification via reversal of mitochondrial function and restoration of Gas6/Axl/Akt survival pathway. | 2012 | J. Cell. Mol. Med. | pmid:21362131 |
| Uzkeser H et al. | Anti-inflammatory and antinociceptive effects of salbutamol on acute and chronic models of inflammation in rats: involvement of an antioxidant mechanism. | 2012 | Mediators Inflamm. | pmid:22665951 |
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| Mishra P and Samanta L | Oxidative stress and heart failure in altered thyroid States. | 2012 | ScientificWorldJournal | pmid:22649319 |
| Rahman ST et al. | The impact of lipoic acid on endothelial function and proteinuria in quinapril-treated diabetic patients with stage I hypertension: results from the QUALITY study. | 2012 | J. Cardiovasc. Pharmacol. Ther. | pmid:21750253 |
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