Lipoic acid

Lipoic acid is a lipid of Fatty Acyls (FA) class.

Cross Reference

There are no associated biomedical information in the current reference collection.

Current reference collection contains 18962 references associated with Lipoic acid in LipidPedia. Due to lack of full text of references or no associated biomedical terms are recognized in our current text-mining method, we cannot extract any biomedical terms related to diseases, pathways, locations, functions, genes, lipids, and animal models from the associated reference collection.

Users can download the reference list at the bottom of this page and read the reference manually to find out biomedical information.


Here are additional resources we collected from PubChem and MeSH for Lipoic acid

Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Lipoic acid

MeSH term MeSH ID Detail
Hemolysis D006461 131 associated lipids
Stomach Ulcer D013276 75 associated lipids
Kidney Failure, Chronic D007676 51 associated lipids
Diabetes Mellitus D003920 90 associated lipids
Lead Poisoning D007855 4 associated lipids
Hearing Loss, Sensorineural D006319 8 associated lipids
Hypoxia D000860 23 associated lipids
Arrhythmias, Cardiac D001145 42 associated lipids
Acidosis, Lactic D000140 8 associated lipids
Lung Neoplasms D008175 171 associated lipids
Per page 10 20 50 100 | Total 177

PubChem Biomolecular Interactions and Pathways

NCBI Entrez Crosslinks

All references with Lipoic acid

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Per page 10 20 50 100 | Total 4476
Authors Title Published Journal PubMed Link
Ma QL et al. Loss of MAP function leads to hippocampal synapse loss and deficits in the Morris Water Maze with aging. 2014 J. Neurosci. pmid:24849348
Macias-Barragan J et al. [Effects of alpha lipoic acid and pirfenidone on liver cells antioxidant modulation against oxidative damage]. 2014 Rev Med Chil pmid:25693438
Mendes PR et al. Effect of alpha lipoic acid on the blood cell count and iron kinetics in hypertensive patients. 2014 Nutr Hosp pmid:25617577
Thakurta IG et al. Combination of N-acetylcysteine, α-lipoic acid and α-tocopherol substantially prevents the brain synaptosomal alterations and memory and learning deficits of aged rats. 2014 Exp. Gerontol. pmid:24291247
Carter SE et al. The role of prostaglandin and antioxidant availability in recovery from forearm ischemia-reperfusion injury in humans. 2014 J. Hypertens. pmid:24296519
Al-Rasheed NM et al. Prophylactic role of α-lipoic acid and vitamin E against zinc oxide nanoparticles induced metabolic and immune disorders in rat's liver. 2014 Eur Rev Med Pharmacol Sci pmid:24992626
Scumpia PO et al. Alpha-lipoic acid effects on brain glial functions accompanying double-stranded RNA antiviral and inflammatory signaling. 2014 Neurochem. Int. pmid:24269587
Thomas S et al. Stability, cutaneous delivery, and antioxidant potential of a lipoic acid and α-tocopherol codrug incorporated in microemulsions. 2014 J Pharm Sci pmid:24961388
Lim KS et al. Effect of polymer-free TiO2 stent coated with abciximab or alpha lipoic acid in porcine coronary restenosis model. 2014 J Cardiol pmid:24852847
Hatami S et al. Total oxidative status of mouse vitrified pre-antral follicles with pre-treatment of alpha lipoic acid. 2014 Iran. Biomed. J. pmid:24842145
Fu Y et al. In vivo detection of a novel endogenous etheno-DNA adduct derived from arachidonic acid and the effects of antioxidants on its formation. 2014 Free Radic. Biol. Med. pmid:24816294
Connell BJ et al. UPEI-300, a conjugate of lipoic acid and edaravone, mediates neuroprotection in ischemia/reperfusion. 2014 Neurosci. Lett. pmid:24394910
Schwartz L et al. Metabolic treatment of cancer: intermediate results of a prospective case series. 2014 Anticancer Res. pmid:24511042
Nicolson GL Mitochondrial dysfunction and chronic disease: treatment with natural supplements. 2014 Altern Ther Health Med pmid:24473982
Ali SO et al. Modulatory effects of curcumin, silybin-phytosome and alpha-R-lipoic acid against thioacetamide-induced liver cirrhosis in rats. 2014 Chem. Biol. Interact. pmid:24704557
He F et al. Comment on Xu et al.: Meta-analysis of methylcobalamin alone and in combination with lipoic acid in patients with diabetic peripheral neuropathy. 2014 Diabetes Res. Clin. Pract. pmid:24602352
Sherif S et al. The clinical efficacy of cosmeceutical application of liquid crystalline nanostructured dispersions of alpha lipoic acid as anti-wrinkle. 2014 Eur J Pharm Biopharm pmid:24056055
Nasole E et al. Effects of alpha lipoic acid and its R+ enantiomer supplemented to hyperbaric oxygen therapy on interleukin-6, TNF-α and EGF production in chronic leg wound healing. 2014 J Enzyme Inhib Med Chem pmid:23360079
Liu J et al. Reloading functionally ameliorates disuse-induced muscle atrophy by reversing mitochondrial dysfunction, and similar benefits are gained by administering a combination of mitochondrial nutrients. 2014 Free Radic. Biol. Med. pmid:24418157
Amin KA et al. Oxidative hepatotoxicity effects of monocrotaline and its amelioration by lipoic acid, S-adenosyl methionine and vitamin E. 2014 J Complement Integr Med pmid:24413220
Zygmunt M et al. Anti-inflammatory activity of lipoic acid in mice peritonitis model. 2013 Sep-Oct Acta Pol Pharm pmid:24147369
Koriyama Y et al. Anti-inflammatory effects of lipoic acid through inhibition of GSK-3β in lipopolysaccharide-induced BV-2 microglial cells. 2013 Sep-Oct Neurosci. Res. pmid:23892131
Sayın M et al. The dose-dependent neuroprotective effect of alpha-lipoic acid in experimental spinal cord injury. 2013 Jul-Aug Neurol. Neurochir. Pol. pmid:23986424
Durand M and Mach N [Alpha lipoic acid and its antioxidant against cancer and diseases of central sensitization]. 2013 Jul-Aug Nutr Hosp pmid:23889618
Haber A et al. Combating diabetes complications by 1-Fe, a corrole-based catalytic antioxidant. 2013 Jul-Aug J. Diabetes Complicat. pmid:23602197
Mitkov MD et al. Effect of transdermal testosterone or alpha-lipoic acid on erectile dysfunction and quality of life in patients with type 2 diabetes mellitus. 2013 Jan-Mar Folia Med (Plovdiv) pmid:23905488
Nebbioso M et al. Mechanisms of ocular neuroprotection by antioxidant molecules in animal models. 2013 Jan-Mar J. Biol. Regul. Homeost. Agents pmid:23489699
Leu JG et al. Epigallocatechin-3-gallate combined with alpha lipoic acid attenuates high glucose-induced receptor for advanced glycation end products (RAGE) expression in human embryonic kidney cells. 2013 Apr-Jun An. Acad. Bras. Cienc. pmid:23780308
Kondo H et al. β-Adrenergic signaling stimulates osteoclastogenesis via reactive oxygen species. 2013 Am. J. Physiol. Endocrinol. Metab. pmid:23169789
Castro MC et al. Lipoic acid prevents liver metabolic changes induced by administration of a fructose-rich diet. 2013 Biochim. Biophys. Acta pmid:23085069
Arambašić J et al. Alpha-lipoic acid upregulates antioxidant enzyme gene expression and enzymatic activity in diabetic rat kidneys through an O-GlcNAc-dependent mechanism. 2013 Eur J Nutr pmid:23064900
Haack TB et al. Homozygous missense mutation in BOLA3 causes multiple mitochondrial dysfunctions syndrome in two siblings. 2013 J. Inherit. Metab. Dis. pmid:22562699
Inui T et al. Clinical experience of integrative cancer immunotherapy with GcMAF. 2013 Anticancer Res. pmid:23780980
Nishino A et al. The role of oxygen intermediates in the retention time of diacetyl adaptation in the nematode Caenorhabditis elegans. 2013 J Exp Zool A Ecol Genet Physiol pmid:23733487
Strokov IA et al. [Efficacy of thiolepta in diabetic polyneuropathy: results of the study ETIKA]. 2013 Zh Nevrol Psikhiatr Im S S Korsakova pmid:23739501
Zhang H et al. Robust and specific ratiometric biosensing using a copper-free clicked quantum dot-DNA aptamer sensor. 2013 Nanoscale pmid:24056667
Jo SH et al. Alpha-lipoic acid for the prevention of contrast-induced nephropathy in patients undergoing coronary angiography: the ALIVE study - a prospective randomized trial. 2013 Cardiology pmid:23988855
Benson A A conversation with Andrew Benson: reflections on the discovery of the Calvin-Benson cycle. 2013 Photosyn. Res. pmid:23269523
Cai X et al. Pre-protective effect of lipoic acid on injury induced by H2O2 in IPEC-J2 cells. 2013 Mol. Cell. Biochem. pmid:23440503
Rocamonde B et al. Lipoic acid treatment after brain injury: study of the glial reaction. 2013 Clin. Dev. Immunol. pmid:24302959
Uyar IS et al. Alpha lipoic acid attenuates inflammatory response during extracorporeal circulation. 2013 Cardiovasc J Afr pmid:24240384
Xu Q et al. Meta-analysis of methylcobalamin alone and in combination with lipoic acid in patients with diabetic peripheral neuropathy. 2013 Diabetes Res. Clin. Pract. pmid:23664235
Ledesma JC and Aragon CM Acquisition and reconditioning of ethanol-induced conditioned place preference in mice is blocked by the Hâ‚‚Oâ‚‚ scavenger alpha lipoic acid. 2013 Psychopharmacology (Berl.) pmid:22885873
Bobermin LD et al. Lipoic acid protects C6 cells against ammonia exposure through Na⁺-K⁺-Cl⁻ co-transporter and PKC pathway. 2013 Toxicol In Vitro pmid:23880158
Ji D et al. α-Lipoic acid attenuates light insults to neurones. 2013 Biol. Pharm. Bull. pmid:23811555
Jiang T et al. Lipoic acid restores age-associated impairment of brain energy metabolism through the modulation of Akt/JNK signaling and PGC1α transcriptional pathway. 2013 Aging Cell pmid:23815272
Li RJ et al. Alpha-lipoic acid ameliorates oxidative stress by increasing aldehyde dehydrogenase-2 activity in patients with acute coronary syndrome. 2013 Tohoku J. Exp. Med. pmid:23238616
Kleinkauf-Rocha J et al. Lipoic acid increases glutamate uptake, glutamine synthetase activity and glutathione content in C6 astrocyte cell line. 2013 Int. J. Dev. Neurosci. pmid:23286972
Panzella L et al. Synthesis and bioactivity profile of 5-s-lipoylhydroxytyrosol-based multidefense antioxidants with a sizeable (poly)sulfide chain. 2013 J. Agric. Food Chem. pmid:23256907
Pinkerton NM et al. Formation of stable nanocarriers by in situ ion pairing during block-copolymer-directed rapid precipitation. 2013 Mol. Pharm. pmid:23259920