Sterculic acid

Sterculic acid is a lipid of Fatty Acyls (FA) class. The involved functions are known as Metabolic Inhibition, Anabolism, Cell secretion, fatty acid desaturation and triglyceride biosynthetic process. Sterculic acid often locates in Protoplasm and Extracellular. The related lipids are Fatty Acids and sterculic acid.

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Introduction

To understand associated biological information of Sterculic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Sterculic acid?

There are no associated biomedical information in the current reference collection.

Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Sterculic acid

MeSH term MeSH ID Detail
Neoplasms D009369 13 associated lipids
Mammary Neoplasms, Experimental D008325 67 associated lipids
Body Weight D001835 333 associated lipids
Total 3

PubChem Associated disorders and diseases

What pathways are associated with Sterculic acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Sterculic acid?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Sterculic acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Sterculic acid?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with Sterculic acid?

There are no associated biomedical information in the current reference collection.

What common seen animal models are associated with Sterculic acid?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Sterculic acid

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Authors Title Published Journal PubMed Link
Hao P et al. Sterculic Acid and Its Analogues Are Potent Inhibitors of Toxoplasma gondii. 2016 Korean J. Parasitol. pmid:27180571
Huang JD et al. 7-Ketocholesterol-induced inflammation signals mostly through the TLR4 receptor both in vitro and in vivo. 2014 PLoS ONE pmid:25036103
Herrera-Meza MS et al. Dietary anhydrous milk fat naturally enriched with conjugated linoleic acid and vaccenic acid modify cardiovascular risk biomarkers in spontaneously hypertensive rats. 2013 Int J Food Sci Nutr pmid:23360131
Kadegowda AK et al. Inhibition of stearoyl-CoA desaturase 1 reduces lipogenesis in primary bovine adipocytes. 2013 Lipids pmid:23929455
Bionaz M et al. A novel dynamic impact approach (DIA) for functional analysis of time-course omics studies: validation using the bovine mammary transcriptome. 2012 PLoS ONE pmid:22438877
Schneider AC et al. Conversion of t11t13 CLA into c9t11 CLA in Caco-2 cells and inhibition by sterculic oil. 2012 PLoS ONE pmid:22427892
Huang JD et al. Sterculic acid antagonizes 7-ketocholesterol-mediated inflammation and inhibits choroidal neovascularization. 2012 Biochim. Biophys. Acta pmid:22342272
Bichi E et al. Inhibition of ∆9-desaturase activity with sterculic acid: effect on the endogenous synthesis of cis-9 18:1 and cis-9, trans-11 18:2 in dairy sheep. 2012 J. Dairy Sci. pmid:22916929
Yu XH et al. Characterization and analysis of the cotton cyclopropane fatty acid synthase family and their contribution to cyclopropane fatty acid synthesis. 2011 BMC Plant Biol. pmid:21612656
Zhang L et al. A multiplexed cell assay in HepG2 cells for the identification of delta-5, delta-6, and delta-9 desaturase and elongase inhibitors. 2010 J Biomol Screen pmid:20086206
Jeyakumar SM et al. Fatty acid desaturation index correlates with body mass and adiposity indices of obesity in Wistar NIN obese mutant rat strains WNIN/Ob and WNIN/GR-Ob. 2009 Nutr Metab (Lond) pmid:19519902
Gratraud P et al. Oleic acid biosynthesis in Plasmodium falciparum: characterization of the stearoyl-CoA desaturase and investigation as a potential therapeutic target. 2009 PLoS ONE pmid:19707292
Bionaz M and Loor JJ Gene networks driving bovine milk fat synthesis during the lactation cycle. 2008 BMC Genomics pmid:18671863
Dillon R et al. Development of a novel LC/MS method to quantitate cellular stearoyl-CoA desaturase activity. 2008 Anal. Chim. Acta pmid:18790132
Soulard P et al. Development of a high-throughput screening assay for stearoyl-CoA desaturase using rat liver microsomes, deuterium labeled stearoyl-CoA and mass spectrometry. 2008 Anal. Chim. Acta pmid:18790133
Obert JC et al. A quantitative method for the determination of cyclopropenoid fatty acids in cottonseed, cottonseed meal, and cottonseed oil (Gossypium hirsutum) by high-performance liquid chromatography. 2007 J. Agric. Food Chem. pmid:17323967
Buist PH Commentary on F.E. Gomez et al., "Effects of sterculic acid on stearoyl-CoA desaturase in differentiating 3T3-L1 adipocytes". 2005 Biochem. Biophys. Res. Commun. pmid:15910739
Phetsuksiri B et al. Unique mechanism of action of the thiourea drug isoxyl on Mycobacterium tuberculosis. 2003 J. Biol. Chem. pmid:14559907
Gomez FE et al. Effects of sterculic acid on stearoyl-CoA desaturase in differentiating 3T3-L1 adipocytes. 2003 Biochem. Biophys. Res. Commun. pmid:12504086
Legrand P et al. Inhibiting delta9-desaturase activity impairs triacylglycerol secretion in cultured chicken hepatocytes. 1997 J. Nutr. pmid:9039824