Malonic acid

Malonic acid is a lipid of Fatty Acyls (FA) class. Malonic acid is associated with abnormalities such as Malonic aciduria. The involved functions are known as Vmax, Regulation, Biochemical Pathway, Citric Acid Cycle and intermediary metabolism. Malonic acid often locates in Body tissue, Mitochondria, soluble and NADH dehydrogenase complex. The associated genes with Malonic acid are ACACA gene, ACSF3 gene, Recombinant Proteins, NKS1 gene and Homologous Gene. The related lipids are Fatty Acids and Butyric Acid.

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Introduction

To understand associated biological information of Malonic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Malonic acid?

Malonic acid is suspected in Malonic aciduria and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Malonic acid

MeSH term MeSH ID Detail
Neoplasms, Muscle Tissue D009379 2 associated lipids
Hemorrhagic Fever with Renal Syndrome D006480 3 associated lipids
Teratoma D013724 4 associated lipids
Neurofibromatosis 1 D009456 4 associated lipids
Hemoglobinopathies D006453 7 associated lipids
Neoplasms D009369 13 associated lipids
Abscess D000038 13 associated lipids
Ischemia D007511 18 associated lipids
Brain Edema D001929 20 associated lipids
Parkinsonian Disorders D020734 20 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with Malonic acid

Lipid pathways are not clear in current pathway databases. We organized associated pathways with Malonic acid through full-text articles, including metabolic pathways or pathways of biological mechanisms.

Related references are published most in these journals:

Pathway name Related literatures
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PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Malonic acid?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Malonic acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Malonic acid?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with Malonic acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Malonic acid?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Malonic acid

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Authors Title Published Journal PubMed Link
Ghosh SK et al. Highly enantioselective and recyclable organocatalytic Michael addition of malonates to α,β-unsaturated aldehydes in aqueous media. 2012 Org. Biomol. Chem. pmid:22976596
Vujčić M et al. A comparative study of DNA binding and cell cycle phase perturbation by the dinuclear complex of Cd(II) with the condensation product of 2-acetylpyridine and malonic acid dihydrazide N',N'(2) -bis[(1E)-1-(2-pyridyl)ethylidene]propanedihydrazide. 2011 May-Jun J. Biochem. Mol. Toxicol. pmid:21671309
Montavon TJ et al. Three-component reaction discovery enabled by mass spectrometry of self-assembled monolayers. 2011 Nat Chem pmid:22169871
Hench J et al. A tissue-specific approach to the analysis of metabolic changes in Caenorhabditis elegans. 2011 PLoS ONE pmid:22162770
Li C and Zhou HM The role of manganese superoxide dismutase in inflammation defense. 2011 Enzyme Res pmid:21977313
Damrauer SM et al. A20 modulates lipid metabolism and energy production to promote liver regeneration. 2011 PLoS ONE pmid:21437236
Pryde KR and Hirst J Superoxide is produced by the reduced flavin in mitochondrial complex I: a single, unified mechanism that applies during both forward and reverse electron transfer. 2011 J. Biol. Chem. pmid:21393237
Pagani I et al. Complete genome sequence of Marivirga tractuosa type strain (H-43). 2011 Stand Genomic Sci pmid:21677852
Tomasiak TM et al. Geometric restraint drives on- and off-pathway catalysis by the Escherichia coli menaquinol:fumarate reductase. 2011 J. Biol. Chem. pmid:21098488
Kim SH et al. Metabolic profiling and predicting the free radical scavenging activity of guava (Psidium guajava L.) leaves according to harvest time by 1H-nuclear magnetic resonance spectroscopy. 2011 Biosci. Biotechnol. Biochem. pmid:21670527