Malonic acid

Malonic acid is a lipid of Fatty Acyls (FA) class. Malonic acid is associated with abnormalities such as Malonic aciduria. The involved functions are known as Vmax, Regulation, Biochemical Pathway, Citric Acid Cycle and intermediary metabolism. Malonic acid often locates in Body tissue, Mitochondria, soluble and NADH dehydrogenase complex. The associated genes with Malonic acid are ACACA gene, ACSF3 gene, Recombinant Proteins, NKS1 gene and Homologous Gene. The related lipids are Fatty Acids and Butyric Acid.

Cross Reference

Introduction

To understand associated biological information of Malonic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Malonic acid?

Malonic acid is suspected in Malonic aciduria and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
Loading... please refresh the page if content is not showing up.

Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Malonic acid

MeSH term MeSH ID Detail
Neoplasms, Muscle Tissue D009379 2 associated lipids
Hemorrhagic Fever with Renal Syndrome D006480 3 associated lipids
Teratoma D013724 4 associated lipids
Neurofibromatosis 1 D009456 4 associated lipids
Hemoglobinopathies D006453 7 associated lipids
Abscess D000038 13 associated lipids
Neoplasms D009369 13 associated lipids
Ischemia D007511 18 associated lipids
Parkinsonian Disorders D020734 20 associated lipids
Brain Edema D001929 20 associated lipids
Per page 10 20 50 | Total 37

PubChem Associated disorders and diseases

What pathways are associated with Malonic acid

Lipid pathways are not clear in current pathway databases. We organized associated pathways with Malonic acid through full-text articles, including metabolic pathways or pathways of biological mechanisms.

Related references are published most in these journals:

Pathway name Related literatures
Loading... please refresh the page if content is not showing up.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Malonic acid?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
Loading... please refresh the page if content is not showing up.

What functions are associated with Malonic acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Malonic acid?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
Loading... please refresh the page if content is not showing up.

What genes are associated with Malonic acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Malonic acid?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Malonic acid

Download all related citations
Per page 10 20 50 100 | Total 2286
Authors Title Published Journal PubMed Link
Feng LP and Zhao L 2-Amino-anilinium 2-carb-oxy-acetate. 2011 Acta Crystallogr Sect E Struct Rep Online pmid:22090933
Jose DA et al. Allosteric P═O-based receptors for dicarboxylic acids. 2011 Org. Lett. pmid:21667961
Lau SK et al. Transport genes and chemotaxis in Laribacter hongkongensis: a genome-wide analysis. 2011 Cell Biosci pmid:21849034
Lin H et al. The complete genome sequence of 'Candidatus Liberibacter solanacearum', the bacterium associated with potato zebra chip disease. 2011 PLoS ONE pmid:21552483
Ghasemzadeh A and Jaafar HZ Effect of CO(2) enrichment on synthesis of some primary and secondary metabolites in ginger (Zingiber officinale Roscoe). 2011 Int J Mol Sci pmid:21541046
Sloan JL et al. Exome sequencing identifies ACSF3 as a cause of combined malonic and methylmalonic aciduria. 2011 Nat. Genet. pmid:21841779
Alfares A et al. Combined malonic and methylmalonic aciduria: exome sequencing reveals mutations in the ACSF3 gene in patients with a non-classic phenotype. 2011 J. Med. Genet. pmid:21785126
Witkowski A et al. Mammalian ACSF3 protein is a malonyl-CoA synthetase that supplies the chain extender units for mitochondrial fatty acid synthesis. 2011 J. Biol. Chem. pmid:21846720
Kumar P et al. Huntington's disease: pathogenesis to animal models. 2010 Jan-Feb Pharmacol Rep pmid:20360611
Wang Z et al. Photochemical cycling of iron mediated by dicarboxylates: special effect of malonate. 2010 Environ. Sci. Technol. pmid:20000366
Shi T et al. cDNA microarray gene expression profiling of hedgehog signaling pathway inhibition in human colon cancer cells. 2010 PLoS ONE pmid:20957031
George GM et al. Virus-induced gene silencing of plastidial soluble inorganic pyrophosphatase impairs essential leaf anabolic pathways and reduces drought stress tolerance in Nicotiana benthamiana. 2010 Plant Physiol. pmid:20605913
Blum Y et al. A factor model to analyze heterogeneity in gene expression. 2010 BMC Bioinformatics pmid:20598132
Xu H et al. Behavioral and neurobiological changes in C57BL/6 mouse exposed to cuprizone: effects of antipsychotics. 2010 Front Behav Neurosci pmid:20305752
Ruhaak LR et al. Glycan labeling strategies and their use in identification and quantification. 2010 Anal Bioanal Chem pmid:20225063
Smejkalová H et al. Methanol assimilation in Methylobacterium extorquens AM1: demonstration of all enzymes and their regulation. 2010 PLoS ONE pmid:20957036
Xie HZ and Zhang YG μ-Adipato-bis-[chlorido(2,2':6',2''-terpyridine)-copper(II)] tetra-hydrate. 2010 Acta Crystallogr Sect E Struct Rep Online pmid:21588166
Eshtiagh-Hosseini H et al. catena-Poly[diacridinium [zinc(II)-di-μ-pyrazine-2,3-dicarboxyl-ato-κN,O:O;O:N,O]]. 2010 Acta Crystallogr Sect E Struct Rep Online pmid:21588129
Duez S et al. Towards the synthesis of bisubstrate inhibitors of protein farnesyltransferase: Synthesis and biological evaluation of new farnesylpyrophosphate analogues. 2010 Bioorg. Med. Chem. pmid:20036564
Stevens P and van Elsas JD Genetic and phenotypic diversity of Ralstonia solanacearum biovar 2 strains obtained from Dutch waterways. 2010 Antonie Van Leeuwenhoek pmid:19960250