Malonic acid

Malonic acid is a lipid of Fatty Acyls (FA) class. Malonic acid is associated with abnormalities such as Malonic aciduria. The involved functions are known as Vmax, Regulation, Biochemical Pathway, Citric Acid Cycle and intermediary metabolism. Malonic acid often locates in Body tissue, Mitochondria, soluble and NADH dehydrogenase complex. The associated genes with Malonic acid are ACACA gene, ACSF3 gene, Recombinant Proteins, NKS1 gene and Homologous Gene. The related lipids are Fatty Acids and Butyric Acid.

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Introduction

To understand associated biological information of Malonic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Malonic acid?

Malonic acid is suspected in Malonic aciduria and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Malonic acid

PubChem Associated disorders and diseases

What pathways are associated with Malonic acid

Lipid pathways are not clear in current pathway databases. We organized associated pathways with Malonic acid through full-text articles, including metabolic pathways or pathways of biological mechanisms.

Related references are published most in these journals:

Pathway name Related literatures
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PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Malonic acid?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Malonic acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Malonic acid?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with Malonic acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Malonic acid?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Malonic acid

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Authors Title Published Journal PubMed Link
Cheng Y et al. pH dependence of specific divalent anion binding to the N-lobe of recombinant human transferrin. 1995 Biochemistry pmid:7578099
Bazzett TJ et al. Chronic administration of malonic acid produces selective neural degeneration and transient changes in calbindin immunoreactivity in rat striatum. 1995 Exp. Neurol. pmid:7556544
Maragos WF and Silverstein FS Inhibition of nitric oxide synthase activity attenuates striatal malonate lesions in rats. 1995 J. Neurochem. pmid:7536812
Greene JG and Greenamyre JT Exacerbation of NMDA, AMPA, and L-glutamate excitotoxicity by the succinate dehydrogenase inhibitor malonate. 1995 J. Neurochem. pmid:7536810
Schmehl I et al. Nature of respiratory stimulation in hyperthyroidism: the redox behaviour of cytochrome c. 1995 FEBS Lett. pmid:7498500
Maragos WF and Silverstein FS The mitochondrial inhibitor malonate enhances NMDA toxicity in the neonatal rat striatum. 1995 Brain Res. Dev. Brain Res. pmid:7493402
Jocelyn PC The reduction of diamide by rat liver mitochondria and the role of glutathione. 1978 Biochem. J. pmid:747642
Ye B et al. L-O-(2-malonyl)tyrosine: a new phosphotyrosyl mimetic for the preparation of Src homology 2 domain inhibitory peptides. 1995 J. Med. Chem. pmid:7473554
Parvin R et al. Inhibition of mitochondrial carnitine-acylcarnitine translocase by sulfobetaines. 1980 Can. J. Biochem. pmid:7459685
Masterson E and Chader GJ Pigment epithelial cells in culture. Metabolic pathways required for phagocytosis. 1981 Invest. Ophthalmol. Vis. Sci. pmid:7451071