Malonic acid

Malonic acid is a lipid of Fatty Acyls (FA) class. Malonic acid is associated with abnormalities such as Malonic aciduria. The involved functions are known as Vmax, Regulation, Biochemical Pathway, Citric Acid Cycle and intermediary metabolism. Malonic acid often locates in Body tissue, Mitochondria, soluble and NADH dehydrogenase complex. The associated genes with Malonic acid are ACACA gene, ACSF3 gene, Recombinant Proteins, NKS1 gene and Homologous Gene. The related lipids are Fatty Acids and Butyric Acid.

Cross Reference

Introduction

To understand associated biological information of Malonic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Malonic acid?

Malonic acid is suspected in Malonic aciduria and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Malonic acid

MeSH term MeSH ID Detail
Mitochondrial Diseases D028361 25 associated lipids
Parkinsonian Disorders D020734 20 associated lipids
Neurotoxicity Syndromes D020258 34 associated lipids
Genetic Predisposition to Disease D020022 24 associated lipids
Neurodegenerative Diseases D019636 32 associated lipids
Weight Gain D015430 101 associated lipids
Zellweger Syndrome D015211 39 associated lipids
Teratoma D013724 4 associated lipids
Parkinson Disease D010300 53 associated lipids
Neurofibromatosis 1 D009456 4 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with Malonic acid

Lipid pathways are not clear in current pathway databases. We organized associated pathways with Malonic acid through full-text articles, including metabolic pathways or pathways of biological mechanisms.

Related references are published most in these journals:

Pathway name Related literatures
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PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Malonic acid?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Malonic acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Malonic acid?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with Malonic acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Malonic acid?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Malonic acid

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Authors Title Published Journal PubMed Link
Demin OV et al. [Kinetic modeling of energy metabolism and generation of active forms of oxygen in hepatocyte mitochondria]. 2001 Nov-Dec Mol. Biol. (Mosk.) pmid:11771135
pmid:11772081
Gorrell A et al. Determinants of L-aspartate and IMP recognition in Escherichia coli adenylosuccinate synthetase. 2002 J. Biol. Chem. pmid:11781326
Ozcan C et al. Potassium channel openers protect cardiac mitochondria by attenuating oxidant stress at reoxygenation. 2002 Am. J. Physiol. Heart Circ. Physiol. pmid:11788400
Janausch IG et al. C4-dicarboxylate carriers and sensors in bacteria. 2002 Biochim. Biophys. Acta pmid:11803016
Cecchini G et al. Succinate dehydrogenase and fumarate reductase from Escherichia coli. 2002 Biochim. Biophys. Acta pmid:11803023
Yang XL et al. Photo-induced cytotoxicity of malonic acid [C(60)]fullerene derivatives and its mechanism. 2002 Toxicol In Vitro pmid:11812638
pmid:11825076
pmid:11841298
Okun JG et al. Neurodegeneration in methylmalonic aciduria involves inhibition of complex II and the tricarboxylic acid cycle, and synergistically acting excitotoxicity. 2002 J. Biol. Chem. pmid:11847233