Malonic acid

Malonic acid is a lipid of Fatty Acyls (FA) class. Malonic acid is associated with abnormalities such as Malonic aciduria. The involved functions are known as Vmax, Regulation, Biochemical Pathway, Citric Acid Cycle and intermediary metabolism. Malonic acid often locates in Body tissue, Mitochondria, soluble and NADH dehydrogenase complex. The associated genes with Malonic acid are ACACA gene, ACSF3 gene, Recombinant Proteins, NKS1 gene and Homologous Gene. The related lipids are Fatty Acids and Butyric Acid.

Cross Reference

Introduction

To understand associated biological information of Malonic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Malonic acid?

Malonic acid is suspected in Malonic aciduria and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Malonic acid

MeSH term MeSH ID Detail
Neoplasms, Muscle Tissue D009379 2 associated lipids
Hemorrhagic Fever with Renal Syndrome D006480 3 associated lipids
Teratoma D013724 4 associated lipids
Neurofibromatosis 1 D009456 4 associated lipids
Hemoglobinopathies D006453 7 associated lipids
Abscess D000038 13 associated lipids
Neoplasms D009369 13 associated lipids
Ischemia D007511 18 associated lipids
Parkinsonian Disorders D020734 20 associated lipids
Brain Edema D001929 20 associated lipids
Bacterial Infections D001424 21 associated lipids
Hyperglycemia D006943 21 associated lipids
Genetic Predisposition to Disease D020022 24 associated lipids
Mitochondrial Diseases D028361 25 associated lipids
Brain Diseases D001927 27 associated lipids
Catalepsy D002375 30 associated lipids
Neurodegenerative Diseases D019636 32 associated lipids
Diarrhea D003967 32 associated lipids
Hypothyroidism D007037 32 associated lipids
Memory Disorders D008569 33 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with Malonic acid

Lipid pathways are not clear in current pathway databases. We organized associated pathways with Malonic acid through full-text articles, including metabolic pathways or pathways of biological mechanisms.

Related references are published most in these journals:

Pathway name Related literatures
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PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Malonic acid?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Malonic acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Malonic acid?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with Malonic acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Malonic acid?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Malonic acid

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Authors Title Published Journal PubMed Link
Hench J et al. A tissue-specific approach to the analysis of metabolic changes in Caenorhabditis elegans. 2011 PLoS ONE pmid:22162770
Paul D et al. Proteome and membrane fatty acid analyses on Oligotropha carboxidovorans OM5 grown under chemolithoautotrophic and heterotrophic conditions. 2011 PLoS ONE pmid:21386900
Lallous N et al. The PHD finger of human UHRF1 reveals a new subgroup of unmethylated histone H3 tail readers. 2011 PLoS ONE pmid:22096602
Bauwens M et al. Radioiodinated phenylalkyl malonic acid derivatives as pH-sensitive SPECT tracers. 2012 PLoS ONE pmid:22719886
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Lim S et al. D-β-hydroxybutyrate is protective in mouse models of Huntington's disease. 2011 PLoS ONE pmid:21931779
Chanumolu SK et al. UniDrug-target: a computational tool to identify unique drug targets in pathogenic bacteria. 2012 PLoS ONE pmid:22431985
Thein M et al. DipA, a pore-forming protein in the outer membrane of Lyme disease spirochetes exhibits specificity for the permeation of dicarboxylates. 2012 PLoS ONE pmid:22590556
Anand K et al. Structural analyses of the Slm1-PH domain demonstrate ligand binding in the non-canonical site. 2012 PLoS ONE pmid:22574179
Trushina E et al. Defects in mitochondrial dynamics and metabolomic signatures of evolving energetic stress in mouse models of familial Alzheimer's disease. 2012 PLoS ONE pmid:22393443
Tran QM et al. Out of plane distortions of the heme b of Escherichia coli succinate dehydrogenase. 2012 PLoS ONE pmid:22393428
Totir M et al. Macro-to-micro structural proteomics: native source proteins for high-throughput crystallization. 2012 PLoS ONE pmid:22393408
Scotti C et al. Cell-cycle inhibition by Helicobacter pylori L-asparaginase. 2010 PLoS ONE pmid:21085483