| MeSH term | MeSH ID | Detail |
|---|---|---|
| Body Weight | D001835 | 333 associated lipids |
| Lung Neoplasms | D008175 | 171 associated lipids |
| Edema | D004487 | 152 associated lipids |
| Hemolysis | D006461 | 131 associated lipids |
| Glioma | D005910 | 112 associated lipids |
| Weight Gain | D015430 | 101 associated lipids |
| Insulin Resistance | D007333 | 99 associated lipids |
| Brain Ischemia | D002545 | 89 associated lipids |
| Alzheimer Disease | D000544 | 76 associated lipids |
| Mammary Neoplasms, Experimental | D008325 | 67 associated lipids |
| Parkinson Disease | D010300 | 53 associated lipids |
| Nerve Degeneration | D009410 | 53 associated lipids |
| Metabolism, Inborn Errors | D008661 | 46 associated lipids |
| Zellweger Syndrome | D015211 | 39 associated lipids |
| Nervous System Diseases | D009422 | 37 associated lipids |
| Fever | D005334 | 35 associated lipids |
| Neurotoxicity Syndromes | D020258 | 34 associated lipids |
| Memory Disorders | D008569 | 33 associated lipids |
| Hypothyroidism | D007037 | 32 associated lipids |
| Neurodegenerative Diseases | D019636 | 32 associated lipids |
Malonic acid
Malonic acid is a lipid of Fatty Acyls (FA) class. Malonic acid is associated with abnormalities such as Malonic aciduria. The involved functions are known as Vmax, Regulation, Biochemical Pathway, Citric Acid Cycle and intermediary metabolism. Malonic acid often locates in Body tissue, Mitochondria, soluble and NADH dehydrogenase complex. The associated genes with Malonic acid are ACACA gene, ACSF3 gene, Recombinant Proteins, NKS1 gene and Homologous Gene. The related lipids are Fatty Acids and Butyric Acid.
Cross Reference
Introduction
To understand associated biological information of Malonic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with Malonic acid?
Malonic acid is suspected in Malonic aciduria and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
Loading... please refresh the page if content is not showing up.
Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with Malonic acid
PubChem Associated disorders and diseases
What pathways are associated with Malonic acid
Lipid pathways are not clear in current pathway databases. We organized associated pathways with Malonic acid through full-text articles, including metabolic pathways or pathways of biological mechanisms.
Related references are published most in these journals:
| Pathway name | Related literatures |
|---|
Loading... please refresh the page if content is not showing up.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with Malonic acid?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
Loading... please refresh the page if content is not showing up.
What functions are associated with Malonic acid?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with Malonic acid?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
Loading... please refresh the page if content is not showing up.
What genes are associated with Malonic acid?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with Malonic acid?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with Malonic acid
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| pmid:11931967 | ||||
| pmid:11975518 | ||||
| pmid:11975526 | ||||
| pmid:11978131 | ||||
| Mackler B et al. | Studies of the development of congenital anomalies in rats. III. Effects of inhibition of mitochondrial energy systems on embryonic development. | 1975 | Teratology | pmid:1198336 |
| Maragos WF et al. | Mitochondrial toxin inhibition of [(3)H]dopamine uptake into rat striatal synaptosomes. | 2002 | Biochem. Pharmacol. | pmid:11996892 |
| pmid:12005506 | ||||
| pmid:12007091 | ||||
| pmid:12008022 | ||||
| pmid:12012410 | ||||
| Miki T | [Inhibitors of complex I and II of the mitochondrial respiratory chain]. | 2002 | Nippon Rinsho | pmid:12013844 |
| pmid:12020876 | ||||
| Nørbaek R et al. | Anthocyanins from flowers of Cichorium intybus. | 2002 | Phytochemistry | pmid:12031425 |
| Saito N et al. | Acylated anthocyanins from the blue-violet flowers of Anemone coronaria. | 2002 | Phytochemistry | pmid:12031427 |
| Shin S et al. | Structure of malonamidase E2 reveals a novel Ser-cisSer-Lys catalytic triad in a new serine hydrolase fold that is prevalent in nature. | 2002 | EMBO J. | pmid:12032064 |
| DoganKoruznjak J et al. | Synthesis, photochemical synthesis and antitumor evaluation of novel derivatives of thieno[3',2':4,5]thieno[2,3-c]quinolones. | 2002 | Chem. Pharm. Bull. | pmid:12036023 |
| Uenishi J and Hamada M | Stereospecific substitution of enantiomerically pure 1-(2-pyridinyl)ethyl methanesulfonate with beta-dicarbony compounds. | 2002 | Chem. Pharm. Bull. | pmid:12036035 |
| pmid:12049975 | ||||
| pmid:12051770 | ||||
| pmid:12054936 | ||||
| Ogier de Baulny H and Saudubray JM | Branched-chain organic acidurias. | 2002 | Semin Neonatol | pmid:12069539 |
| Zeevalk GD et al. | Protection of malonate-induced GABA but not dopamine loss by GABA transporter blockade in rat striatum. | 2002 | Exp. Neurol. | pmid:12093096 |
| Dedeoglu A et al. | Mice overexpressing 70-kDa heat shock protein show increased resistance to malonate and 3-nitropropionic acid. | 2002 | Exp. Neurol. | pmid:12093104 |
| Hassel B et al. | Cerebral dicarboxylate transport and metabolism studied with isotopically labelled fumarate, malate and malonate. | 2002 | J. Neurochem. | pmid:12124442 |
| Pain F et al. | In vivo quantification of localized neuronal activation and inhibition in the rat brain using a dedicated high temporal-resolution beta +-sensitive microprobe. | 2002 | Proc. Natl. Acad. Sci. U.S.A. | pmid:12136134 |
| Liang X et al. | Structure and dynamics of metallomacrocycles: recognition of zinc xylyl-bicyclam by an HIV coreceptor. | 2002 | J. Am. Chem. Soc. | pmid:12149014 |
| Saraswathi NT and Vijayan M | X-ray studies on crystalline complexes involving amino acids and peptides. XXXIX. Crystal structures of malonic acid complexes of DL- and L-histidine. Preservation of aggregation pattern on reversal of chirality. | 2002 | Acta Crystallogr., B | pmid:12149565 |
| pmid:12154133 | ||||
| Rancan F et al. | Cytotoxicity and photocytotoxicity of a dendritic C(60) mono-adduct and a malonic acid C(60) tris-adduct on Jurkat cells. | 2002 | J. Photochem. Photobiol. B, Biol. | pmid:12167314 |
| pmid:12182598 | ||||
| Asanuma T et al. | Assessment of neuroprotective ability of a spin trap, alpha-phenyl-N-tert-butylnitrone, against malonate-induced ischemic injury of rat brain by apparent water diffusion coefficient mapping. | 2002 | Neurosci. Lett. | pmid:12183031 |
| pmid:12183100 | ||||
| pmid:12203348 | ||||
| pmid:12206751 | ||||
| Kim YS | Malonate metabolism: biochemistry, molecular biology, physiology, and industrial application. | 2002 | J. Biochem. Mol. Biol. | pmid:12359084 |
| Loopuijt LD | Local application of L- threo-hydroxyaspartate and malonate in rats in vivo induces rigidity and damages neurons of the substantia nigra, pars compacta. | 2002 | J Neural Transm | pmid:12373561 |
| Lash LH et al. | Protection of NRK-52E cells, a rat renal proximal tubular cell line, from chemical-induced apoptosis by overexpression of a mitochondrial glutathione transporter. | 2002 | J. Pharmacol. Exp. Ther. | pmid:12388626 |
| pmid:12392401 | ||||
| Dickins RS et al. | Structural, luminescence, and NMR studies of the reversible binding of acetate, lactate, citrate, and selected amino acids to chiral diaqua ytterbium, gadolinium, and europium complexes. | 2002 | J. Am. Chem. Soc. | pmid:12392417 |
| Burckhardt BC et al. | The renal Na(+)-dependent dicarboxylate transporter, NaDC-3, translocates dimethyl- and disulfhydryl-compounds and contributes to renal heavy metal detoxification. | 2002 | J. Am. Soc. Nephrol. | pmid:12397032 |
| pmid:12434365 | ||||
| An JH et al. | Symbiotic effects of deltamatB Rhizobium leguminosarum bv. trifolii mutant on clovers. | 2002 | Mol. Cells | pmid:12442899 |
| Pomytkin IA and Kolesova OE | Key role of succinate dehydrogenase in insulin-induced inactivation of protein tyrosine phosphatases. | 2002 | Bull. Exp. Biol. Med. | pmid:12447467 |
| Saraswathi NT and Vijayan M | X-ray studies on crystalline complexes involving amino acids and peptides. XL. Conformational variability, recurring and new features of aggregation, and effect of chirality in the malonic acid complexes of DL- and L-arginine. | 2002 | Acta Crystallogr., B | pmid:12456986 |
| Petersén A et al. | Evidence for dysfunction of the nigrostriatal pathway in the R6/1 line of transgenic Huntington's disease mice. | 2002 | Neurobiol. Dis. | pmid:12460553 |
| Cervellati R et al. | Evaluation of antioxidant activity of some natural polyphenolic compounds using the Briggs-Rauscher reaction method. | 2002 | J. Agric. Food Chem. | pmid:12475261 |
| Colsenet R et al. | A straightforward detection of deprotonated conformers of malonic acid by solid-state 13C NMR spectroscopy. | 2002 | Angew. Chem. Int. Ed. Engl. | pmid:12481345 |
| Basak K and Majumdar SK | Effect of some inhibitors on kanamycin formation by Streptomyces kanamyceticus. | 1976 | Folia Microbiol. (Praha) | pmid:1248783 |
| Sweet DH et al. | Organic anion transporter 3 (Slc22a8) is a dicarboxylate exchanger indirectly coupled to the Na+ gradient. | 2003 | Am. J. Physiol. Renal Physiol. | pmid:12488248 |
| Armentero MT et al. | Dopamine receptor agonists mediate neuroprotection in malonate-induced striatal lesion in the rat. | 2002 | Exp. Neurol. | pmid:12504889 |